T. Vary

发表

Unilateral Hindlimb Immobilization Decreases Muscle Mass in Part by Proteasome - Dependent Proteolysis but Independent of Protein Synthesis and Translation Initiation Factors

C. Lang, L. Jefferson, B. Krawiec, 2005 .

Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis.

C. Lang, L. Jefferson, B. Krawiec, 2005, American journal of physiology. Endocrinology and metabolism.

Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.

D. Breuillé, C. Buffière, C. Obled, 1999, The Journal of endocrinology.

Hypertrophy of skeletal muscle in diabetic rats in response to chronic resistance exercise.

J. Miller, C. Lang, J. Fluckey, 1999, Journal of applied physiology.

Regulation of TNF‐induced oxygen radical production in human neutrophils: role of δ‐PKC

T. Vary, L. Kilpatrick, Shuang Sun, 2010, Journal of leukocyte biology.

Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice.

Pengxiang She, C. Lynch, T. Vary, 2009, The Journal of nutrition.

Sepsis-induced changes in protein synthesis: differential effects on fast- and slow-twitch muscles.

S. Kimball, T. Vary, 1992, The American journal of physiology.

Insulin stimulation of protein synthesis in rat skeletal muscle following resistance exercise is maintained with advancing age.

W. Evans, J. Fluckey, L. Jefferson, 1996, The journals of gerontology. Series A, Biological sciences and medical sciences.

Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.

O. Ilkayeva, C. Lang, C. Lynch, 2012, Schizophrenia bulletin.

Regulation of protein synthesis by insulin.

S. Kimball, L. Jefferson, T. Vary, 1994, Annual review of physiology.

Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis.

C. Lang, R. Frost, T. Vary, 2003, Endocrinology.

Regulation of skeletal muscle protein turnover during sepsis: mechanisms and mediators.

S. Kimball, T. Vary, R. Cooney, 1997, Shock.

Endotoxin-induced decrease in muscle protein synthesis is associated with changes in eIF2B, eIF4E, and IGF-I.

C. Lang, S. Kimball, L. Jefferson, 2000, American journal of physiology. Endocrinology and metabolism.

Inter-organ protein and carbohydrate metabolic relationships during sepsis: necessary evils or uncanny coincidences?

T. Vary, 1999, Current opinion in clinical nutrition and metabolic care.

Altered expression of eukaryotic initiation factor 2B in skeletal muscle during sepsis.

S. Kimball, L. Jefferson, T. Vary, 1996, The American journal of physiology.

Interleukin-1 receptor antagonist prevents sepsis-induced inhibition of protein synthesis.

T. Vary, R. Cooney, J. Vannice, 1994, The American journal of physiology.

Protection of ischemic myocardium from metabolic products.

T. Vary, K. Ichihara, J. Robishaw, 2009, Acta medica Scandinavica. Supplementum.

Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver.

J. Siegel, T. Vary, 1989, The American journal of physiology.

Regulation of Protein Metabolism in Muscle

S. Kimball, L. Jefferson, T. Vary, 2011 .

Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy

Xueqian Zhang, J. Cheung, C. Caldarera, 2012, Amino Acids.

Relationship between adenine nucleotide metabolism and irreversible ischemic tissue damage in isolated perfused rat heart.

T. Vary, E. Angelakos, S. Schaffer, 1979, Circulation research.

Insulin-like growth factor-2 activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases

T. Vary, Q. Meng, A. Karinch, 2003, Journal of Gastrointestinal Surgery.

Hyperoxia inhibits protein synthesis and increases eIF2α phosphorylation in the newborn rat lung.

T. Vary, J. Shenberger, Lianqin Zhang, 2010, American journal of physiology. Lung cellular and molecular physiology.

Biochemical approaches for nutritional support of skeletal muscle protein metabolism during sepsis

C. Lynch, T. Vary, 2004, Nutrition Research Reviews.

Amrinone prevents the inhibition of muscle pyruvate dehydrogenase complex activity during sepsis.

T. Vary, 1996, Shock.

TNF binding protein prevents hyperlactatemia and inactivation of PDH complex in skeletal muscle during sepsis.

T. Vary, R. Cooney, G. Maish, 1998, The Journal of surgical research.

Sex-dependent differences in the regulation of myocardial protein synthesis following long-term ethanol consumption.

S. Kimball, T. Vary, A. Sumner, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Indinavir alters regulators of protein anabolism and catabolism in skeletal muscle.

C. Lang, L. Hong-Brown, R. Frost, 2005, American journal of physiology. Endocrinology and metabolism.

DIMINISHED ERK 1/2 AND p38 MAPK PHOSPHORYLATION IN SKELETAL MUSCLE DURING SEPSIS

C. Lang, T. Vary, G. Deiter, 2004, Shock.

TNF-α impairs heart and skeletal muscle protein synthesis by altering translation initiation

A. Nairn, C. Lang, R. Frost, 2002 .

Regulation of peptide-chain initiation in muscle during sepsis by interleukin-1 receptor antagonist.

T. Vary, L. Voisin, R. Cooney, 1996, The American journal of physiology.

Regulation of eukaryotic initiation factor-2 expression during sepsis.

S. Kimball, T. Vary, A. Karinch, 1994, The American journal of physiology.

Regulation of eukaryotic initiation factor-2B activity in muscle of diabetic rats.

S. Kimball, L. Jefferson, T. Vary, 1993, The American journal of physiology.

Biochemical and Molecular Actions of Nutrients Leucine Regulates Translation Initiation in Rat Skeletal Muscle Via Enhanced eIF 4 G Phosphorylation 1 , 2

D. Bolster, S. Kimball, L. Jefferson, 2004 .

Inhibition of carnitine palmitoyl-CoA transferase activity and fatty acid oxidation by lactate and oxfenicine in cardiac muscle.

T. Vary, D. Bielefeld, J. R. Neely, 1985, Journal of molecular and cellular cardiology.

Nutrient signaling components controlling protein synthesis in striated muscle.

C. Lynch, T. Vary, 2007, The Journal of nutrition.

IGF-I/IGFBP-3 binary complex modulates sepsis-induced inhibition of protein synthesis in skeletal muscle.

C. Lang, S. Kimball, L. Jefferson, 2000, American journal of physiology. Endocrinology and metabolism.

Insulin fails to stimulate muscle protein synthesis in sepsis despite unimpaired signaling to 4E-BP1 and S6K1.

S. Kimball, L. Jefferson, T. Vary, 2001, American journal of physiology. Endocrinology and metabolism.

IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats.

C. Lang, R. Frost, T. Vary, 2004, American journal of physiology. Endocrinology and metabolism.

Regulation of protein synthesis by insulin.

S. Kimball, L. Jefferson, T. Vary, 1994, Annual review of physiology.

Regulation of skeletal muscle protein turnover during sepsis.

T. Vary, 1998, Current opinion in clinical nutrition and metabolic care.

Regulation of Pyruvate and Amino Acid Metabolism

W. Souba, C. Lynch, T. Vary, 2007 .

Down Regulation of Pyruvate Dehydrogenase Complex in Skeletal Muscle during Sepsis: Implications for Sepsis-Induced Hyperlactatemia

T. Vary, 1999 .

Chronic infusion of interleukin 1 induces hyperlactatemia and altered regulation of lactate metabolism in skeletal muscle.

T. Vary, R. Cooney, G. Maish, 1999, JPEN. Journal of parenteral and enteral nutrition.

Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.

S. Kimball, L. Jefferson, T. Anthony, 2000, The Journal of nutrition.

Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats.

C. Lynch, T. Vary, S. Hutson, 2002, American journal of physiology. Endocrinology and metabolism.

from refed, diabetic rats increases in protein synthesis in epitrochlearis muscles Selected Contribution: IGF-I antibody prevents Plasticity in Skeletal, Cardiac, and Smooth Muscle:

M. Fedele, T. Vary, P. Farrell, 2005 .

Selected Contribution: IGF-I antibody prevents increases in protein synthesis in epitrochlearis muscles from refed, diabetic rats.

M. Fedele, T. Vary, P. Farrell, 2001, Journal of applied physiology.

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine.

C. Lang, C. Lynch, R. Frost, 2010, American journal of physiology. Endocrinology and metabolism.

Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle.

C. Lang, R. Frost, T. Vary, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

rats: contribution of hepatic tissue - and endotoxin-treated α Leucine metabolism in TNF-

A. Nairn, C. Lang, R. Frost, 2011 .

Oral leucine enhances myocardial protein synthesis in rats acutely administered ethanol.

T. Vary, 2009, The Journal of nutrition.

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle.

Pengxiang She, C. Lynch, T. Vary, 2007, Cell metabolism.

Acute oral leucine administration stimulates protein synthesis during chronic sepsis through enhanced association of eukaryotic initiation factor 4G with eukaryotic initiation factor 4E in rats.

T. Vary, 2007, The Journal of nutrition.

Amino acids and insulin are both required to regulate assembly of the eIF4E z eIF4G complex in rat skeletal muscle

S. Kimball, L. Jefferson, T. Vary, 2001 .

Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle.

S. Kimball, L. Jefferson, T. Vary, 2001, American journal of physiology. Endocrinology and metabolism.

Regulation of amino acid–sensitive TOR signaling by leucine analogues in adipocytes

S. Kimball, L. Jefferson, C. Lynch, 2000, Journal of cellular biochemistry.

Amino acid-induced stimulation of translation initiation in rat skeletal muscle.

S. Kimball, L. Jefferson, T. Vary, 1999, The American journal of physiology.

Amino acid-induced stimulation of translation initiation in rat skeletal muscle.

S. Kimball, L. Jefferson, T. Vary, 1999, American journal of physiology. Endocrinology and metabolism.

Diazoxide-induced insulin deficiency greatly reduced muscle protein synthesis in rats: involvement of eIF4E.

S. Kimball, L. Jefferson, T. Vary, 1999, The American journal of physiology.

Effect of dietary protein on translation initiation in rat skeletal muscle and liver.

S. Kimball, L. Jefferson, F. Yoshizawa, 1998, The American journal of physiology.

Effect of dietary protein on translation initiation in rat skeletal muscle and liver.

S. Kimball, L. Jefferson, F. Yoshizawa, 1998, American journal of physiology. Endocrinology and metabolism.

Modulation of skeletal muscle protein synthesis by amino acids and insulin during sepsis.

T. Vary, K. Gray, C. Jurasinski, 1995, Metabolism: clinical and experimental.

The effect of ischaemia on the activity of pyruvate dehydrogenase complex in rat heart.

T. Vary, P. J. Randle, 1984, Journal of molecular and cellular cardiology.

Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide- 1-b-D-Ribonucleoside Prevents Leucine- Stimulated Protein Synthesis in Rat

C. Lang, Abid A. Kazi, R. Frost, 2008 .

Regulation of muscle protein synthesis during sepsis and inflammation.

C. Lang, R. Frost, T. Vary, 2007, American journal of physiology. Endocrinology and metabolism.

Long-term alcohol administration inhibits synthesis of both myofibrillar and sarcoplasmic proteins in heart.

T. Vary, G. Deiter, 2005, Metabolism: clinical and experimental.

Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol.

A. Nairn, C. Lang, T. Vary, 2004, Alcoholism, clinical and experimental research.

BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.

C. Lang, C. Lynch, T. Vary, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Sepsis alters pyruvate dehydrogenase kinase activity in skeletal muscle

T. Vary, S. Hazen, 1999, Molecular and Cellular Biochemistry.

Increased pyruvate dehydrogenase kinase activity in response to sepsis.

T. Vary, 1991, The American journal of physiology.

Regulation of glucose metabolism by altered pyruvate dehydrogenase activity. I. Potential site of insulin resistance in sepsis.

J. Siegel, T. Vary, T. Sato, 1986, JPEN. Journal of parenteral and enteral nutrition.

Mechanism of IL-1 induced inhibition of protein synthesis in skeletal muscle.

C. Lang, T. Vary, R. Cooney, 1999, Shock.

Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

S. Kimball, L. Jefferson, T. Anthony, 2000, The Journal of nutrition.

Mechanisms regulating skeletal muscle glucose metabolism in sepsis.

T. Vary, W. A. Brennan, C. Jurasinski, 1995, Shock.

Phosphatidylinositol 3-kinase and p70 s6 kinase participate in the regulation of protein turnover in skeletal muscle by insulin and insulin-like growth factor I.

T. Vary, D. Dardevet, J. Grizard, 1996, Endocrinology.

response to chronic resistance exercise Hypertrophy of skeletal muscle in diabetic rats in

C. Lang, J. Fluckey, M. Fedele, 2015 .

Severe diabetes prohibits elevations in muscle protein synthesis after acute resistance exercise in rats.

C. Lang, M. Fedele, S. Kimball, 2000, Journal of applied physiology.

Reduced 40S initiation complex formation in skeletal muscle during sepsis

S. Kimball, T. Vary, C. Jurasinski, 2004, Molecular and Cellular Biochemistry.

Differential Phosphorylation of Translation Initiation Regulators 4EBP1, S6k1, and Erk 1/2 Following Inhibition of Alcohol Metabolism in Mouse Heart

C. Lang, T. Vary, 2008, Cardiovascular Toxicology.

Skeletal muscle protein synthesis and degradation exhibit sexual dimorphism after chronic alcohol consumption but not acute intoxication.

C. Lang, R. Frost, T. Vary, 2007, American journal of physiology. Endocrinology and metabolism.

Alcohol intoxication impairs phosphorylation of S6K1 and S6 in skeletal muscle independently of ethanol metabolism.

C. Lang, R. Frost, T. Vary, 2004, Alcoholism, clinical and experimental research.

Thermal injury impairs cardiac protein synthesis and is associated with alterations in translation initiation.

C. Lang, R. Frost, T. Vary, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

IGF-I induced phosphorylation of S6K1 and 4E-BP1 in heart is impaired by acute alcohol intoxication.

C. Lang, R. Frost, T. Vary, 2003, Alcoholism, clinical and experimental research.

Eukaryotic initiation factors and protein synthesis after resistance exercise in rats.

M. Fedele, S. Kimball, L. Jefferson, 2000, Journal of applied physiology.

Effect of sepsis on eIE4E availability in skeletal muscle.

S. Kimball, T. Vary, 2000, American journal of physiology. Endocrinology and metabolism.

Castration differentially alters basal and leucine-stimulated tissue protein synthesis in skeletal muscle and adipose tissue.

C. Lang, T. Vary, A. Pruznak, 2009, American journal of physiology. Endocrinology and metabolism.

Carbonic anhydrase III in obese Zucker rats.

C. Lynch, T. Vary, S. Dodgson, 1993, The American journal of physiology.

Acute alcohol intoxication increases REDD1 in skeletal muscle.

C. Lang, R. Frost, T. Vary, 2008, Alcoholism, clinical and experimental research.

of protein synthesis in moderately diabetic rats Effects of intensity of acute-resistance exercise on rates

B. Macias, J. Fluckey, M. Fedele, 2015 .

Effects of intensity of acute-resistance exercise on rates of protein synthesis in moderately diabetic rats.

M. Fedele, S. Kimball, L. Jefferson, 1998, Journal of applied physiology.

Inhibition of muscle protein synthesis by alcohol is associated with modulation of eIF2B and eIF4E.

C. Lang, S. Kimball, L. Jefferson, 1999, American journal of physiology. Endocrinology and metabolism.

Oxygen and Substrate Supply of the Myocardium

F. Prinzen, R. Reneman, D. Lübbers, 1982 .

IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis.

C. Lang, T. Vary, R. Cooney, 1996, The American journal of physiology.

Amrinone prevents muscle protein wasting during chronic sepsis.

T. Vary, L. Kilpatrick, C. Jurasinski, 1995, American Journal of Physiology.

Role of central IL-1 in regulating peripheral IGF-I during endotoxemia and sepsis.

C. Lang, T. Vary, R. Cooney, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Insulin-like growth factor I accelerates protein synthesis in skeletal muscle during sepsis.

T. Vary, C. Jurasinski, 1995, The American journal of physiology.

Leucine in food mediates some of the postprandial rise in plasma leptin concentrations.

C. Lynch, T. Vary, S. Hutson, 2006, American journal of physiology. Endocrinology and metabolism.

Alcohol myopathy: impairment of protein synthesis and translation initiation.

C. Lang, S. Kimball, R. Frost, 2001, The international journal of biochemistry & cell biology.

Effects of cardiac work on electrical potential gradient across mitochondrial membrane in perfused rat hearts.

G. Salama, J. Duszyński, T. Vary, 1993, The American journal of physiology.

Differential regulation of skeletal muscle protein turnover by insulin and IGF-I after bacteremia.

D. Breuillé, C. Buffière, C. Obled, 1998, American journal of physiology. Endocrinology and metabolism.

Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues.

S. Kimball, L. Jefferson, T. Vary, 1992, The Biochemical journal.

Sepsis inhibits synthesis of myofibrillar and sarcoplasmic proteins: modulation by interleukin-1 receptor antagonist.

T. Vary, R. Cooney, J. Beers, 1996, Shock.

Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle.

C. Lang, S. Kimball, L. Jefferson, 2003, American journal of physiology. Endocrinology and metabolism.

Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver.

C. Lang, R. Frost, T. Vary, 2000, Alcoholism, clinical and experimental research.

Chronic alcohol feeding impairs hepatic translation initiation by modulating eIF2 and eIF4E.

C. Lang, S. Kimball, L. Jefferson, 1999, American journal of physiology. Endocrinology and metabolism.

Phosphorylation of eukaryotic initiation factor eIF2Bepsilon in skeletal muscle during sepsis.

S. Kimball, T. Vary, G. Deiter, 2002, American journal of physiology. Endocrinology and metabolism.

Phosphorylation of eukaryotic initiation factor eIF2Bepsilon in skeletal muscle during sepsis.

S. Kimball, T. Vary, G. Deiter, 2002, American journal of physiology. Endocrinology and metabolism.

Effects of chronic alcohol consumption on regulation of myocardial protein synthesis.

C. Lang, C. Lynch, T. Vary, 2001, American journal of physiology. Heart and circulatory physiology.

Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis.

S. Kimball, L. Jefferson, T. Vary, 2010, American journal of physiology. Endocrinology and metabolism.

Ectopic expression of eIF2B ε in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis

S. Kimball, L. Jefferson, T. Vary, 2010 .

Ectopic expression of eIF 2 B ε in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis

S. Kimball, L. Jefferson, T. Vary, 2010 .

Properties of Carnitine Incorporation in Working Swine Hearts: Effects of Coronary Flow, Ischemia, and Excess Fatty Acids

T. Vary, A. Liedtke, S. Nellis, 1982, Circulation research.

Alcohol impairs leucine-mediated phosphorylation of 4 EBP 1 , S 6 K 1 , eIF 4 G , and mTOR in skeletal muscle

C. Lang, S. Kimball, L. Jefferson, 2003 .

IGF-I in perfused rat skeletal muscle Role of eIF4E in stimulation of protein synthesis by

Guoyao Wu, K. Shah, Wence Wang, 2011 .

Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F.

C. Lang, R. Frost, T. Vary, 2000, American journal of physiology. Endocrinology and metabolism.

Role of eIF4E in stimulation of protein synthesis by IGF-I in perfused rat skeletal muscle.

S. Kimball, L. Jefferson, T. Vary, 2000, American journal of physiology. Endocrinology and metabolism.

Role of eIF 4 E in stimulation of protein synthesis by IGF-I in perfused rat skeletal muscle

S. Kimball, L. Jefferson, T. Vary, 1999 .

Biochemical and Molecular Action of Nutrients Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway 1

S. Kimball, L. Jefferson, T. Anthony, 2000 .

Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase.

C. Lang, C. Lynch, T. Vary, 2010, The Journal of nutrition.

Assessing effects of alcohol consumption on protein synthesis in striated muscles.

C. Lang, T. Vary, 2008, Methods in molecular biology.

Chronic alcohol feeding impairs mTOR(Ser 2448) phosphorylation in rat hearts.

T. Vary, G. Deiter, Rachel Lantry, 2007, Alcoholism, clinical and experimental research.

54 – Models of Endocrine Insufficiency

T. Vary, 2001 .

Effects of tumor necrosis factor-binding protein on hepatic protein synthesis during chronic sepsis.

S. Kimball, T. Vary, R. Cooney, 2000, The Journal of surgical research.

TNF-binding protein ameliorates inhibition of skeletal muscle protein synthesis during sepsis.

S. Kimball, T. Vary, R. Cooney, 1999, American journal of physiology. Endocrinology and metabolism.

TNF-binding protein ameliorates inhibition of skeletal muscle protein synthesis during sepsis.

S. Kimball, T. Vary, R. Cooney, 1999, The American journal of physiology.

Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle.

C. Lynch, T. Vary, L. Kilpatrick, 2005, American journal of physiology. Endocrinology and metabolism.

Fraction of hepatic cytosolic acetyl-CoA derived from glucose in vivo: relation to PDH phosphorylation state.

T. Vary, M. Hellerstein, M. Christiansen, 1991, The American journal of physiology.

Inhibition of muscle protein synthesis by alcohol is associated with modulation of eIF2B and eIF4E.

C. Lang, S. Kimball, L. Jefferson, 1999, The American journal of physiology.

Molecular mechanisms responsible for alcohol-induced myopathy in skeletal muscle and heart.

C. Lang, R. Frost, T. Vary, 2005, The international journal of biochemistry & cell biology.

Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and plasma triacylglycerols. Abolition by prior fasting.

O. Park, T. Vary, M. Hellerstein, 1992, The Biochemical journal.

Regulation of amino acid arginine transport by lipopolysaccharide and nitric oxide in intestinal epithelial IEC-6 cells

W. Souba, T. Vary, H. Choudry, 2005, Journal of Gastrointestinal Surgery.

Analysis of physiological amino acids using dabsyl derivatization and reversed-phase liquid chromatography.

T. Vary, D. Drnevich, 1993, Journal of chromatography.

Regulation of hepatic protein synthesis in chronic inflammation and sepsis.

S. Kimball, T. Vary, 1992, The American journal of physiology.

Pharmacological reversal of abnormal glucose regulation, BCAA utilization, and muscle catabolism in sepsis by dichloroacetate.

J. Siegel, T. Vary, B. Tall, 1987, The Journal of trauma.

Metabolic effects of partial reversal of pyruvate dehydrogenase activity by dichloroacetate in sepsis.

J. Siegel, T. Vary, B. Tall, 1988, Circulatory shock.

Role of central IL-1 in regulating peripheral IGF-I during endotoxemia and sepsis.

C. Lang, T. Vary, R. Cooney, 1998, The American journal of physiology.

Regulation of protein synthesis after acute resistance exercise in diabetic rats.

C. Lang, M. Fedele, S. Kimball, 1999, American journal of physiology. Endocrinology and metabolism.

Interleukin-1 receptor antagonist attenuates tumor necrosis factor-induced alterations in wound breaking strength.

T. Vary, R. Cooney, H. Ehrlich, 1999, The Journal of trauma.

Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n-octanoate.

T. Vary, P. J. Randle, H. Fatania, 1986, The Biochemical journal.

Augmented insulin action on rates of protein synthesis after resistance exercise in rats.

J. Fluckey, L. Jefferson, T. Vary, 1996, The American journal of physiology.

Growth hormone does not attenuate the inhibitory effects of sepsis on wound healing

C. Lang, T. Vary, R. Cooney, 2000, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Molecular mechanisms regulating myocardial glucose oxidation.

A. L. Kerbey, T. Vary, P. J. Randle, 1985, Basic research in cardiology.

Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis.

T. Vary, Jonathan H. Martin, A. Karinch, 2008, American journal of physiology. Endocrinology and metabolism.

TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation.

A. Nairn, C. Lang, R. Frost, 2002, American journal of physiology. Endocrinology and metabolism.

Chronic alcohol feeding impairs hepatic translation initiation by modulating eIF2 and eIF4E.

C. Lang, S. Kimball, L. Jefferson, 1999, The American journal of physiology.

Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver.

J. Siegel, T. Vary, T. Sato, 1986, The American journal of physiology.

Oxygen debt and metabolic acidemia as quantitative predictors of mortality and the severity of the ischemic insult in hemorrhagic shock

J. Siegel, T. Vary, C. Dunham, 1991, Critical care medicine.

SEPSIS‐INDUCED ALTERATIONS IN PYRUVATE DEHYDROGENASE COMPLEX ACTIVITY IN RAT SKELETAL MUSCLE: EFFECTS ON PLASMA LACTATE

T. Vary, 1996, Shock.

Central interleukin-1 partially mediates endotoxin-induced changes in glucose metabolism.

C. Lang, T. Vary, R. Cooney, 1996, The American journal of physiology.

A biochemical basis for depressed ketogenesis in sepsis.

J. Siegel, T. Vary, T. Sato, 1986, The Journal of trauma.

Capsaicin-sensitive nerves regulate the metabolic response to abdominal sepsis.

C. Lang, T. Vary, R. Cooney, 2003, The Journal of surgical research.

Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside prevents leucine-stimulated protein synthesis in rat skeletal muscle.

C. Lang, Abid A. Kazi, R. Frost, 2008, The Journal of nutrition.

Rapamycin limits formation of active eukaryotic initiation factor 4F complex following meal feeding in rat hearts.

C. Lynch, T. Vary, G. Deiter, 2007, The Journal of nutrition.

Control of energy metabolism of heart muscle.

T. Vary, D. Reibel, J. R. Neely, 1981, Annual review of physiology.

A mechanism for reduced myocardial carnitine levels in diabetic animals.

T. Vary, J. R. Neely, 1982, The American journal of physiology.

Sodium dependence of carnitine transport in isolated perfused adult rat hearts.

T. Vary, J. R. Neely, 1983, The American journal of physiology.

Characterization of carnitine transport in isolated perfused adult rat hearts.

T. Vary, J. R. Neely, 1982, The American journal of physiology.

Control of myocardial levels of CoA and carnitine.

T. Vary, J. Robishaw, J. R. Neely, 1982, Journal of molecular and cellular cardiology.

Rapamycin blunts nutrient stimulation of eIF4G, but not PKCε phosphorylation, in skeletal muscle

S. Kimball, L. Jefferson, C. Lynch, 2007 .

Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

C. Lynch, T. Vary, 2006, American journal of physiology. Endocrinology and metabolism.

Nutrient regulation of PKCε is mediated by leucine, not insulin, in skeletal muscle

C. Lynch, T. Vary, L. Kilpatrick, 2005 .

Nutrient signaling to muscle and adipose tissue by leucine.

J. Zempleni, K. Dakshinamurti, C. Lynch, 2005 .

Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR.

C. Lynch, T. Vary, S. Hutson, 2003, American journal of physiology. Endocrinology and metabolism.

Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue.

L. Jefferson, C. Lynch, T. Vary, 2002, American journal of physiology. Endocrinology and metabolism.

Deleterious effects of alcohol intoxication on the heart: arrhythmias to cardiomyopathies.

V. Preedy, R. Watson, T. Vary, 2004 .

Activation of pyruvate dehydrogenase improves heart function and metabolism after hemorrhagic shock.

J. Kline, T. Vary, P. Maiorano, 1997, Journal of molecular and cellular cardiology.

Effect of dichloroacetate on plasma and hepatic amino acids in sterile inflammation and sepsis.

J. Siegel, T. Vary, B. Tall, 1989, Archives of surgery.

Intravascular plastic catheters. How they potentiate tumor necrosis factor release and exacerbate complications associated with sepsis.

B. Munger, D. Remick, P. K. Davis, 1991, Archives of surgery.

Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases

T. Vary, Q. Meng, A. Karinch, 2003, Journal of Gastrointestinal Surgery.

Protein kinase C activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases.

W. Souba, T. Vary, Q. Meng, 2002, The Journal of surgical research.

Metabolic acidosis stimulates intestinal glutamine absorption

W. Souba, T. Vary, Q. Meng, 2003, Journal of Gastrointestinal Surgery.

Activation of intestinal arginine transport by protein kinase c is mediated by mitogen-activated protein kinases

W. Souba, T. Vary, Q. Meng, 2002, Journal of Gastrointestinal Surgery.

Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy

Xueqian Zhang, J. Cheung, C. Caldarera, 2012, Amino Acids.

Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats

C. Lang, T. Vary, G. Nystrom, 2009, Nutrition & metabolism.

Regulation of protein synthesis after acute resistance exercise in diabetic rats.

C. Lang, M. Fedele, S. Kimball, 1999, American Journal of Physiology.

Cellular energy status modulates translational control mechanisms in ischemic-reperfused rat hearts.

S. Kimball, L. Jefferson, T. Vary, 2005, American journal of physiology. Heart and circulatory physiology.

Acute alcohol intoxication enhances myocardial eIF4G phosphorylation despite reducing mTOR signaling.

T. Vary, S. Goodman, G. Deiter, 2005, American journal of physiology. Heart and circulatory physiology.

Skeletal and cardiac myopathy in HIV-1 transgenic rats.

C. Lang, L. Hong-Brown, Pengxiang She, 2008, American journal of physiology. Endocrinology and metabolism.

Functional proteomic analysis reveals sex-dependent differences in structural and energy-producing myocardial proteins in rat model of alcoholic cardiomyopathy.

C. Hollenbeak, S. Kimball, C. Lynch, 2011, Physiological genomics.

CYTOKINE-TRIGGERED DECREASES IN LEVELS OF PHOSPHORYLATED EUKARYOTIC INITIATION FACTOR 4G IN SKELETAL MUSCLE DURING SEPSIS

C. Lang, T. Vary, G. Deiter, 2006, Shock.

IGF-I stimulates protein synthesis in skeletal muscle through multiple signaling pathways during sepsis.

T. Vary, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Effect of central administration of interleukin-1 receptor antagonist on protein synthesis in skeletal muscle, kidney, and liver during sepsis.

T. Vary, Mary Palopoli, C. Lloyd, 2003, Metabolism: clinical and experimental.

Inhibition of skeletal muscle protein synthesis in septic intra-abdominal abscess.

J. Siegel, J. A. Smith, T. Vary, 1987, The Journal of trauma.

Inhibition of Glycogen Synthase Kinase 3&bgr; Activity with Lithium In Vitro Attenuates Sepsis-Induced Changes in Muscle Protein Turnover

C. Lang, T. Vary, Stephen Bertsch, 2011, Shock.

Meal feeding stimulates phosphorylation of multiple effector proteins regulating protein synthetic processes in rat hearts.

C. Lynch, T. Vary, 2006, The Journal of nutrition.

Potentiation of decreased pyruvate dehydrogenase activity by inflammatory stimuli in sepsis.

T. Vary, L. F. Martin, L. Martin, 1993, Circulatory shock.

Impact of chronic alcohol ingestion on cardiac muscle protein expression.

C. Lynch, T. Vary, B. Stanley, 2010, Alcoholism, clinical and experimental research.

Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver.

A. Nairn, C. Lang, T. Vary, 2002, Alcoholism, clinical and experimental research.

Alcohol-induced increases in insulin-like growth factor binding protein-1 are partially mediated by TNF.

C. Lang, R. Frost, T. Vary, 2002, Alcoholism, clinical and experimental research.

Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

T. Gardner, T. Vary, Eun-Gyoung Hong, 2007, American journal of physiology. Endocrinology and metabolism.

MODULATION OF SKELETAL MUSCLE LACTATE METABOLISM FOLLOWING BACTEREMIA BY INSULIN OR INSULIN‐LIKE GROWTH FACTOR‐I: EFFECTS OF PENTOXIFYLLINE

T. Vary, D. Dardevet, C. Pouyet, 1997, Shock.

Insulin-induced activation of pyruvate dehydrogenase complex in skeletal muscle of diabetic rats.

T. Vary, P. Feldhoff, J. Arnold, 1993, Metabolism: clinical and experimental.

IGF-I activates the eIF4F system in cardiac muscle in vivo

C. Lang, T. Vary, 2005, Molecular and Cellular Biochemistry.

Fatty acid and glucose utilization in isolated, working newborn pig hearts.

T. Vary, H. Schuler, J. C. Werner, 1983, American Journal of Physiology.

Abnormal metabolic control in the septic multiple organ failure syndrome: pharmacotherapy for altered fuel control mechanisms.

J. Siegel, T. Vary, A. Rivkind, 1989, Progress in clinical and biological research.

BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.

C. Lang, C. Lynch, T. Vary, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.

O. Ilkayeva, C. Lang, C. Lynch, 2012, Schizophrenia bulletin.

Impact of chronic alcohol ingestion on cardiac muscle protein expression.

C. Lynch, T. Vary, B. Stanley, 2010, Alcoholism, clinical and experimental research.

Effect of dietary protein on translation initiation in rat skeletal muscle and liver.

S. Kimball, L. Jefferson, F. Yoshizawa, 1998, American journal of physiology. Endocrinology and metabolism.

Prevention of skeletal muscle catabolism in sepsis does not impair visceral protein metabolism.

T. Vary, R. Cooney, E. Owens, 1996, The American journal of physiology.

Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis.

T. Vary, Jonathan H. Martin, A. Karinch, 2008, American journal of physiology. Endocrinology and metabolism.