G. Xiao

发表

The Tuberous Sclerosis 2 Gene Product, Tuberin, Functions as a Rab5 GTPase Activating Protein (GAP) in Modulating Endocytosis*

E. Golemis, G. Xiao, F. Shoarinejad, 1997, The Journal of Biological Chemistry.

Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK

S. Jhanwar, J. Testa, P. Poulikakos, 2006, Oncogene.

The NF2 Tumor Suppressor Gene Product, Merlin, Inhibits Cell Proliferation and Cell Cycle Progression by Repressing Cyclin D1 Expression

S. Jhanwar, J. Testa, R. Pestell, 2005, Molecular and Cellular Biology.

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region.

J. Declue, R. Wienecke, G. Xiao, 1996, Proceedings of the National Academy of Sciences of the United States of America.

c-Met Axis − miR-34 a − Mesotheliomas with Enriched Cancer Stem Cells via a p 53 Tumor Suppressor Alterations Cooperate to Drive Aggressive

Yue Wu, J. Testa, V. Kolev, 2014 .

Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis.

Yue Wu, J. Testa, V. Kolev, 2014, Cancer research.

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.

A. Knudson, J. Testa, G. Xiao, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The FHIT gene product is highly expressed in the cytoplasm of renal tubular epithelium and is down-regulated in kidney cancers.

T. Goodrow, G. Xiao, R. Yeung, 1997, The American journal of pathology.

A multi-institutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas.

V. Rusch, J. Testa, K. Khalili, 1998, Cancer research.

A Clue to the Therapy of Neurofibromatosis Type 2: NF2/Merlin Is a PAK1 Inhibitor

J. Testa, M. Giovannini, G. Xiao, 2004, Cancer journal.

Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction Pathway

G. Xiao, A. Cuconati, T. Block, 2007, Journal of Virology.

Activation of p21-Activated Kinase 2 by Human Immunodeficiency Virus Type 1 Nef Induces Merlin Phosphorylation

J. Testa, V. Arora, J. Garcia, 2005, Journal of Virology.

Sustained cardiomyocyte DNA synthesis in whole embryo cultures lacking the TSC2 gene product.

G. Xiao, R. Yeung, M. Soonpaa, 1997, The American journal of physiology.

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways.

G. V. Vande Woude, J. Testa, G. Woude, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the FHIT gene and its product in squamous cell carcinomas of the head and neck

K. Bleicher, T. Goodrow, S. C. Liu, 1998, Oncogene.

Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer

Yue Wu, Y. Liu, G. Xiao, 2017, Oncotarget.

Inhibition of mesothelioma cancer stem‐like cells with adenovirus‐mediated NK4 gene therapy

Yue Wu, J. Testa, G. Xiao, 2015, International journal of cancer.

Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

G. Xiao, K. Yao, Qiu-zhen Liu, 2013, Journal of Translational Medicine.

Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer.

T. Zhu, G. Xiao, Qiuzhen Liu, 2015, The American journal of Chinese medicine.

Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat

G. Xiao, F. Jin, R. Yeung, 1995, Molecular carcinogenesis.

AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.

J. Testa, Y. Mitsuuchi, G. Xiao, 2001, Cancer research.

NF2: The wizardry of merlin

Jonathan Chernoff, J. Testa, J. Chernoff, 2003, Genes, chromosomes & cancer.

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth

S. Jhanwar, J. Testa, A. Kane, 2005, Oncogene.

Protein expression and functional analysis of the FHIT gene in human tumor cells.

F. Kaye, G. Otterson, W. Niklińska, 1998, Journal of the National Cancer Institute.

p21-activated Kinase Links Rac/Cdc42 Signaling to Merlin*

J. Testa, J. Chernoff, G. Xiao, 2002, The Journal of Biological Chemistry.

Cancer stem‐like cell properties are regulated by EGFR/AKT/β–catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

Ying Liu, Gong Zhang, Kai-Tai Yao, 2013, The FEBS journal.

“Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury”

Shidan Wang, Tao Wang, Y. Hoshida, 2022 .

Identification of tuberous sclerosis 2 messenger RNA splice variants that are conserved and differentially expressed in rat and human tissues.

G. Xiao, R. Yeung, F. Jin, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Germ-line Tsc2 mutation in a dominantly inherited cancer model defines a novel family of rat intracisternal-A particle elements.

G. Xiao, R. Yeung, F. Jin, 1995, Oncogene.

Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction Pathway

G. Xiao, A. Cuconati, T. Block, 2007, Journal of Virology.