V. Ramesh

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The TSC1 Tumor Suppressor Hamartin Interacts with Neurofilament-L and Possibly Functions as a Novel Integrator of the Neuronal Cytoskeleton*

Mark J. Bowser, Vijaya Ramesh, L. A. Haddad, 2002, The Journal of Biological Chemistry.

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.

T. Jacks, J. Gusella, V. Ramesh, 1997, Genes & development.

Merlin: the neurofibromatosis 2 tumor suppressor.

J. Gusella, V. Ramesh, M. Maccollin, 1999, Biochimica et biophysica acta.

TorsinA in PC12 cells: Localization in the endoplasmic reticulum and response to stress

Vijaya Ramesh, X. Breakefield, P. Hanson, 2003, Journal of neuroscience research.

Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels.

A. Reiner, P. Kwok, D. Reich, 2007, American journal of human genetics.

Functions of MUC16 in corneal epithelial cells.

I. Gipson, V. Ramesh, M. Gilmore, 2007, Investigative ophthalmology & visual science.

Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas.

D. Louis, J. Gusella, A. von Deimling, 1994, Cancer research.

The NF2 Tumor Suppressor Merlin and the ERM Proteins Interact with N-WASP and Regulate Its Actin Polymerization Function*

J. Gusella, S. Snapper, A. Lyubimova, 2005, Journal of Biological Chemistry.

The neurofibromatosis 2 protein product merlin selectively binds F-actin but not G-actin, and stabilizes the filaments through a lateral association.

J. Hartwig, M. James, C. Gonzalez-agosti, 2001, The Biochemical journal.

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2

J. Hartwig, J. Gusella, M. James, 2004, Oncogene.

Phosphorylation of Tuberin as a Novel Mechanism for Somatic Inactivation of the Tuberous Sclerosis Complex Proteins in Brain Lesions

Túlio Marcos Santos, A. Stemmer-Rachamimov, E. Thiele, 2004, Cancer Research.

A 34 bp Deletion Within TSC2 is a Rare Polymorphism, not a Pathogenic Mutation

D. Kwiatkowski, V. Ramesh, P. Roberts, 2003, Annals of human genetics.

Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions.

A. Stemmer-Rachamimov, D. Kwiatkowski, D. Louis, 2001, American journal of human genetics.

Developmental expression of the tuberous sclerosis proteins tuberin and hamartin

D. Louis, A. Stemmer-Rachamimov, R. Beauchamp, 2001, Acta Neuropathologica.

L. A. Haddad, N. Smith, V. Murthy, 2000, American journal of physiology. Renal physiology.

Exon scanning of the entire TSC2 gene for germline mutations in 40 unrelated patients with tuberous sclerosis

L. Ozelius, R. Beauchamp, V. Ramesh, 1998, Human mutation.

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model

A. Stemmer-Rachamimov, X. Breakefield, R. Bronson, 2015, Neurobiology of Disease.

Aberrant Hyperactivation of Akt and Mammalian Target of Rapamycin Complex 1 Signaling in Sporadic Chordomas

G. Nielsen, A. Rosenberg, V. Ramesh, 2009, Clinical Cancer Research.

A region of deletion on chromosome 22q13 is common to human breast and colorectal cancers.

J. Gusella, A. Rustgi, V. Ramesh, 2000, Cancer research.

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

H. Wakimoto, D. Cahill, R. Martuza, 2016, Neuro-oncology.

SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma

Clayton K. Collings, V. Ramesh, W. Bi, 2022, Nature Genetics.

Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.

D. Lenartz, R. Wellenreuther, J. Gusella, 1995, The American journal of pathology.

Regulation of mTOR Complex 2 Signaling in Neurofibromatosis 2–Deficient Target Cell Types

J. Gusella, A. Stemmer-Rachamimov, Hua Li, 2012, Molecular Cancer Research.

Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth

J. Gusella, A. Stemmer-Rachamimov, M. James, 2008, Neurobiology of Disease.

Neurofibromatosis 2 gene in human colorectal cancer.

J. Gusella, A. Rustgi, R. Beauchamp, 1995, Cancer genetics and cytogenetics.

Molecular basis of ornithine aminotransferase deficiency in B-6-responsive and -nonresponsive forms of gyrate atrophy.

J. Gusella, E. Berson, V. Ramesh, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The E3 Ubiquitin Ligase Protein Associated with Myc (Pam) Regulates Mammalian/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling in Vivo through N- and C-terminal Domains*

P. Bhide, M. James, S. Bahl, 2012, The Journal of Biological Chemistry.

Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2

A. Stemmer-Rachamimov, D. Welling, M. Giovannini, 2022, Molecular therapy. Methods & clinical development.

An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin).

J. Gusella, V. Ramesh, H. Maruta, 1994, The Journal of biological chemistry.

Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin.

T. Jacks, R. Hynes, V. Ramesh, 2005, Experimental cell research.

Mutational analysis of patients with neurofibromatosis 2.

D. Louis, M. Short, V. Ramesh, 1994, American journal of human genetics.

DNA diagnosis of neurofibromatosis 2. Altered coding sequence of the merlin tumor suppressor in an extended pedigree.

J. Gusella, V. Ramesh, J. Trofatter, 1993, JAMA.

Chromosomal localization of the gene for human B-cell antigen CD40

J. Gusella, R. Geha, V. Ramesh, 1993, Somatic cell and molecular genetics.

Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma

R. Beauchamp, Lei Xu, V. Ramesh, 2020, Scientific Reports.

Role of Merlin/NF2 in mTOR Signaling and Meningioma Growth

A. Stemmer-Rachamimov, V. Ramesh, 2012 .

Signaling and Regulation Regulation of mTOR Complex 2 Signaling in Neuro fi bromatosis 2 – De fi cient Target Cell Types

J. Gusella, A. Stemmer-Rachamimov, Hua Li, 2012 .

Back to the future: Proceedings from the 2010 NF Conference

Karlyne M. Reilly, B. Korf, K. Reilly, 2011, American journal of medical genetics. Part A.

Sacrococcygeal chordomas in patients with tuberous sclerosis complex show somatic loss of TSC1 or TSC2

A. Stemmer-Rachamimov, J. Sampson, V. Ramesh, 2004, Genes, chromosomes & cancer.

Alternative splicing of the tuberous sclerosis 2 (TSC2) gene in human and mouse tissues.

J. Haines, M. Nellist, J. Sampson, 1995, Genomics.

NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins*

J. Gusella, C. Gonzalez-agosti, V. Ramesh, 1998, The Journal of Biological Chemistry.

Inactivation patterns of NF2 and DAL-1/4.1B (EPB41L3) in sporadic meningioma.

Yiping Shen, J. Gusella, A. Stemmer-Rachamimov, 2005, Cancer genetics and cytogenetics.

The merlin tumor suppressor localizes preferentially in membrane ruffles.

J. Gusella, R. Beauchamp, C. Gonzalez-agosti, 1996, Oncogene.

Universal absence of merlin, but not other ERM family members, in schwannomas.

D. Louis, J. Gusella, A. Stemmer-Rachamimov, 1997, The American journal of pathology.

Role of NHERF1, Cystic Fibrosis Transmembrane Conductance Regulator, and cAMP in the Regulation of Aquaporin 9*

M. James, Dennis Brown, N. Pastor-Soler, 2008, Journal of Biological Chemistry.

The B1 Subunit of the H+ATPase Is a PDZ Domain-binding Protein

Dennis Brown, V. Ramesh, V. Marshansky, 2000, The Journal of Biological Chemistry.

Exon scanning for mutation of the NF2 gene in schwannomas.

J. Gusella, B. Seizinger, N. Kley, 1994, Human molecular genetics.

Pain correlates with germline mutation in schwannomatosis how this access benefits you. Your story matters

M. Talkowski, V. Ramesh, J. Jordan, 2018 .

Analysis of molecular domains of epitope-tagged merlin isoforms in Cos-7 cells and primary rat Schwann cells.

R. Beauchamp, C. Gonzalez-agosti, V. Ramesh, 1998, Experimental cell research.

Preclinical Evaluation of Gene Therapy for NF2 Lesions in Mouse Models Using Amplicon Vectors and Prodrug Activation

X. Breakefield, M. Giovannini, Yi Tang, 2001 .

A Close Association of TorsinA and α-Synuclein in Lewy Bodies

B. Hyman, X. Breakefield, P. McLean, 2001 .

Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation.

J. Gusella, R. Beauchamp, Ming-Fen Lee, 2006, Biochemical and biophysical research communications.

What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: New Frontiers

J. Kissil, S. Huson, F. McCormick, 2010, American journal of medical genetics. Part A.

Splicing defect at the ornithine aminotransferase (OAT) locus in gyrate atrophy.

J. Gusella, A. Tobin, E. Berson, 1990, American journal of human genetics.

Molecular basis of cystathionine beta-synthase deficiency in pyridoxine responsive and nonresponsive homocystinuria.

V. Ramesh, J. Kraus, V. Shih, 1993, Human molecular genetics.

Frequency and distribution of NF2 mutations in schwannomas

J. Gusella, V. Ramesh, M. Maccollin, 1996, Genes, chromosomes & cancer.

Reversal of learning deficits in a Tsc2+/− mouse model of tuberous sclerosis

Alcino J. Silva, D. Kwiatkowski, V. Ramesh, 2008, Nature Medicine.

Molecular analysis and prenatal diagnosis of human fumarase deficiency.

V. Ramesh, E. Christensen, O. Elpeleg, 1998, Molecular genetics and metabolism.

Novel mutations detected in the TSC2 gene from both sporadic and familial TSC patients.

M. Short, S. Jóźwiak, V. Ramesh, 1996, Human molecular genetics.

A NHERF binding site links the βPDGFR to the cytoskeleton and regulates cell spreading and migration

M. James, R. Beauchamp, A. Kazlauskas, 2004, Journal of Cell Science.

Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder

M. Daly, B. Neale, J. Gusella, 2013, Molecular Autism.

TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling

S. Haggarty, S. Erdin, M. Talkowski, 2020, Molecular Autism.

Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency

K. Hochedlinger, J. Gusella, M. James, 2015, PloS one.

Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?

Brijesh K. Garg, V. Ramesh, R. Loring, 2020, Biomolecules.

Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer.

D. Louis, J. Gusella, A. Rustgi, 1999, Gastroenterology.

Neuropathology and Molecular Genetics of Neurofibromatosis 2 and Related Tumors

J. Gusella, V. Ramesh, David N. Louis, 1995, Brain pathology.

Analysis of both TSC1 and TSC2 for germline mutations in 126 unrelated patients with tuberous sclerosis

Janine Lewis, L. Ozelius, R. Beauchamp, 1999, Human mutation.

TorsinB – perinuclear location and association with torsinA

X. Breakefield, P. Hanson, R. Beauchamp, 2004, Journal of neurochemistry.

Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin

A. Stemmer-Rachamimov, X. Breakefield, R. Bronson, 2021, Science Advances.

Eighth International Workshop on Human Gene Mapping

K. O. Elliston, D. Cox, K. Kidd, 1984 .

Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer.

E. Chiocca, C. Gonzalez-agosti, V. Ramesh, 1999, Journal of neurosurgery.

Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells.

X. Breakefield, C. Gonzalez-agosti, V. Ramesh, 2000, Human molecular genetics.

NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth

J. Gusella, A. Stemmer-Rachamimov, B. Manning, 2009, Molecular and Cellular Biology.

MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p.

D. Louis, J. Gusella, A. von Deimling, 1994, Human molecular genetics.

Pain correlates with germline mutation in schwannomatosis

S. Erdin, J. Gusella, W. Cai, 2018, Medicine.

Tenth International Workshop on Human Gene Mapping

K. O. Elliston, D. Cox, K. Kidd, 1988 .

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

J. Gusella, B. Seizinger, N. Kley, 1994, Nature Genetics.

The murine NF2 homologue encodes a highly conserved merlin protein with alternative forms.

J. Gusella, V. Ramesh, V. Haase, 1994, Human molecular genetics.

mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition

S. Erdin, J. Gusella, R. Beauchamp, 2020, The Journal of biological chemistry.

EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma

Robert J. Allaway, Steven P. Angus, S. Haggarty, 2018, Neuro-oncology.

Aspects of tuberous sclerosis complex (TSC) protein function in the brain.

V. Ramesh, 2003, Biochemical Society transactions.

The NF2 gene and merlin protein in human osteosarcomas

J. Gusella, A. Stemmer-Rachamimov, G. Nielsen, 1998, Neurogenetics.

Mediator Subunit MED28 (Magicin) Is a Repressor of Smooth Muscle Cell Differentiation*

J. Gusella, A. Näär, R. Beauchamp, 2007, Journal of Biological Chemistry.

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies

Michael Fisher, B. Korf, J. Kissil, 2014, American journal of medical genetics. Part A.

Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF*

Yufang Tang, V. Flockerzi, M. Zhu, 2000, The Journal of Biological Chemistry.

A missense mutation (I278T) in the cystathionine beta-synthase gene prevalent in pyridoxine-responsive homocystinuria and associated with mild clinical phenotype.

V. Ramesh, J. Fringer, G. Berry, 1995, American journal of human genetics.

Pam (Protein associated with Myc) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling.

Rochelle M. Witt, B. Sabatini, Túlio Marcos Santos, 2008, Cellular signalling.

Pam and Its Ortholog Highwire Interact with and May Negatively Regulate the TSC1·TSC2 Complex*

R. Beauchamp, L. A. Haddad, N. Smith, 2004, Journal of Biological Chemistry.

Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma

R. Beauchamp, Lei Xu, V. Ramesh, 2020, Scientific Reports.

The B1 Subunit of the HATPase Is a PDZ Domain-binding Protein COLOCALIZATION WITH NHE-RF IN RENAL B-INTERCALATED CELLS*

Dennis Brown, V. Ramesh, V. Marshansky, 2000 .

Superiority of Denaturing High Performance Liquid Chromatography over single‐stranded conformation and conformation‐sensitive gel electrophoresis for mutation detection in TSC2

D. Kwiatkowski, M. Reeve, Y. Niida, 1999, Annals of human genetics.

Advances in Neurofibromatosis 2 (NF2): A Workshop Report

E. A. Chiocca, W. J. Ramsey, S. Pulst, 2000, Journal of neurogenetics.

Neurofibromatosis 2: loss of merlin's protective spell.

J. Gusella, V. Ramesh, M. Maccollin, 1996, Current opinion in genetics & development.

Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2.

J. Gusella, A. Stemmer-Rachamimov, D. Louis, 1998, Journal of neuropathology and experimental neurology.

A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas

S. Haggarty, Wen-Ning Zhao, J. Gusella, 2015, Oncotarget.

Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system.

A. Stemmer-Rachamimov, D. Louis, R. Beauchamp, 1997, Journal of neuropathology and experimental neurology.

Alternative splicing in protein associated with Myc (Pam) influences its binding to c‐Myc

Mark J. Bowser, Túlio Marcos Santos, P. Bhide, 2006, Journal of neuroscience research.

NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas.

A. Stemmer-Rachamimov, M. James, D. Louis, 2001, The American journal of pathology.

The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

S. C. Liu, P. Bryant, P. Low, 1998 .

Detection of point mutations associated with genetic diseases by an exon scanning technique.

A. Tobin, V. Ramesh, D. Kaufman, 1990, Genomics.

Evidence for Subarachnoid Spread in the Development of Multiple Meningiomas

D. Louis, D. Lenartz, R. Wellenreuther, 1995, Brain pathology.

Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas

Yiping Shen, J. Gusella, A. Stemmer-Rachamimov, 2009, BMC Medical Genomics.

Merlin and the ERM proteins in Schwann cells, neurons and growth cones

V. Ramesh, 2004, Nature Reviews Neuroscience.

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

Robert J. Allaway, Steven P. Angus, S. Haggarty, 2018, PloS one.

Mapping of ornithine aminotransferase gene sequences to mouse Chromosomes 7, X, and 3

J. Gusella, B. Taylor, C. Kozak, 2004, Mammalian Genome.

Localization of the ornithine aminotransferase gene and related sequences on two human chromosomes

R. Eddy, T. Shows, J. Gusella, 1987, Human Genetics.

The ornithine aminotransferase (OAT) locus: analysis of RFLPs in gyrate atrophy.

T. Shows, J. Gusella, V. Ramesh, 1988, American journal of human genetics.

Investigation of gyrate atrophy using a cDNA clone for human ornithine aminotransferase.

J. Gusella, V. Ramesh, J. Allaire, 1986, DNA.

TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion

S. Augood, J. Hedreen, X. Breakefield, 2003, Neurobiology of Disease.

High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy

Eric T. Wang, Steven P. Angus, M. Sur, 2021, Scientific Reports.

A 15‐bp deletion in exon 5 of the ornithine aminotransferase (OAT) locus associated with gyrate atrophy

J. Gusella, V. Ramesh, V. Shih, 1992, Human mutation.

Molecular pathology of gyrate atrophy of the choroid and retina due to ornithine aminotransferase deficiency.

J. Gusella, V. Ramesh, V. Shih, 1991, Molecular biology & medicine.

The ornithine aminotransferase (OAT) locus is linked and distal to D10S20 on the long arm of chromosome 10.

K. Kidd, J. Kidd, N. Simpson, 1988, Cytogenetics and Cell Genetics.

Three novel mutations of the ornithine aminotransferase (OAT) gene in gyrate atrophy.

V. Ramesh, V. Shih, B. Herron, 1992, Genomics.

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

Steven P. Angus, David C. Jones, M. Ferrer, 2021, PloS one.

The Early Onset Dystonia Protein TorsinA Interacts with Kinesin Light Chain 1*

D. Corey, X. Breakefield, P. Hanson, 2004, Journal of Biological Chemistry.

Translatome analysis of Tuberous Sclerosis Complex-1 patient-derived neural progenitor cells reveal rapamycin-dependent and independent alterations

Krzysztof J. Szkop, J. Pelletier, O. Larsson, 2023, Research square.

Interdomain Interaction of Merlin Isoforms and Its Influence on Intermolecular Binding to NHE-RF*

C. Gonzalez-agosti, V. Ramesh, M. Herndon, 1999, The Journal of Biological Chemistry.

Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain

S. Augood, X. Breakefield, D. Standaert, 2003, Brain Research.

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study.

B. Hyman, X. Breakefield, L. Ozelius, 2001, The American journal of pathology.

Neurofibromatosis 2 Tumor Suppressor Protein, Merlin, in Cellular Signaling to Actin Cytoskeleton

V. Ramesh, 2000 .

Prospective phase II trial of the dual mTORC1/2 inhibitor vistusertib for progressive or symptomatic meningiomas in persons with neurofibromatosis 2

A. Stemmer-Rachamimov, M. Giovannini, A. Muzikansky, 2023, Neuro-oncology advances.

Cloning and characterization of a novel human clathrin heavy chain gene (CLTCL).

A. Buckler, V. Ramesh, M. K. McCormick, 1996, Genomics.

Adenosine, prolonged wakefulness, and A1-activated NF-κB DNA binding in the basal forebrain of the rat

R. McCarley, T. Porkka-Heiskanen, R. Basheer, 2001, Neuroscience.

A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas

S. Haggarty, Wen-Ning Zhao, J. Gusella, 2015, Oncotarget.

Extracellular histamine levels in the feline preoptic/anterior hypothalamic area during natural sleep–wakefulness and prolonged wakefulness: An in vivo microdialysis study

R. McCarley, R. Strecker, V. Ramesh, 2002, Neuroscience.

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

H. Wakimoto, D. Cahill, R. Martuza, 2016, Neuro-oncology.

The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis

A. Lloyd, A. Stemmer-Rachamimov, J. Kissil, 2017, American journal of medical genetics. Part A.

Title The path forward : 2015 International Children ' s Tumor Foundation conference on neurofibromatosis type 1 , type 2 , and schwannomatosis Permalink

A. Lloyd, A. Stemmer-Rachamimov, J. Kissil, 2017 .

Aberrant Hyperactivation of Akt and Mammalian Target of Rapamycin Complex 1 Signaling in Sporadic Chordomas

G. Nielsen, A. Rosenberg, V. Ramesh, 2009, Clinical Cancer Research.

Preclinical evaluation of the third-generation, bi-steric mechanistic target of rapamycin complex 1-selective inhibitor RMC-6272 in NF2-deficient models

R. Beauchamp, V. Ramesh, S. Plotkin, 2024, Neuro-oncology advances.

Proteasomal pathway inhibition as a potential therapy for NF2-associated meningioma and schwannoma.

R. Beauchamp, Long-Sheng Chang, V. Ramesh, 2023, Neuro-Oncology.

Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations

Krzysztof J. Szkop, R. Beauchamp, V. Ramesh, 2023, Molecular Autism.

Evolving concepts in meningioma management in the era of genomics.

P. Brastianos, V. Ramesh, S. Plotkin, 2024, Cancer.

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model

A. Stemmer-Rachamimov, X. Breakefield, R. Bronson, 2015, Neurobiology of Disease.