A. Klegeris

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Alpha‐synuclein and its disease‐causing mutants induce ICAM‐1 and IL‐6 in human astrocytes and astrocytoma cells

Andis Klegeris, P. Mcgeer, S. Pelech, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Comparison of student marks obtained by an assessment panel reveals generic problem-solving skills and academic ability as distinct skill sets

A. Klegeris, Emelie Gustafsson, H. Hurren, 2018 .

Non-linear improvement in generic problem-solving skills of university students: a longitudinal study

A. Klegeris, P. Dubois, W. Code, 2019, Higher Education Research & Development.

Impact of problem-based learning in a large classroom setting: student perception and problem-solving skills.

A. Klegeris, H. Hurren, 2011, Advances in physiology education.

Improvement in Generic Problem-Solving Abilities of Students by Use of Tutor-less Problem-Based Learning in a Large Classroom Setting

A. Klegeris, H. Hurren, Manpreet Bahniwal, 2013, CBE life sciences education.

Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases

A. Klegeris, Ellen J. Gates, Anna K. Bernath, 2022, Reviews in the neurosciences.

R-(−)-Deprenyl Inhibits Monocytic THP-1 Cell Neurotoxicity Independently of Monoamine Oxidase Inhibition

P. Mcgeer, A. Klegeris, 2000, Experimental Neurology.

Cobalt(II) β-ketoaminato complexes as novel inhibitors of neuroinflammation.

D. Walker, A. Klegeris, J. Madeira, 2012, European journal of pharmacology.

Extracellular cardiolipin regulates select immune functions of microglia and microglia-like cells

A. Klegeris, Caitlin B. Pointer, Tyler J. Wenzel, 2019, Brain Research Bulletin.

Thrombin and Prothrombin Are Expressed by Neurons and Glial Cells and Accumulate in Neurofibrillary Tangles in Alzheimer Disease Brain

J. Miklossy, P. Mcgeer, A. Klegeris, 2006, Journal of neuropathology and experimental neurology.

Antidepressants inhibit interferon-γ-induced microglial production of IL-6 and nitric oxide

Takahiro A. Kato, S. Kanba, P. Mcgeer, 2007, Experimental Neurology.

Cultured adult porcine astrocytes and microglia express functional interferon-γ receptors and exhibit toxicity towards SH-SY5Y cells

S. Hashioka, A. Klegeris, Manpreet Bahniwal, 2011, Brain Research Bulletin.

Autoxidation of dopamine: a comparison of luminescent and spectrophotometric detection in basic solutions.

S. Greenfield, A. Klegeris, L. Korkina, 1995, Free radical biology & medicine.

Therapeutic approaches to inflammation in neurodegenerative disease

P. Mcgeer, E. Mcgeer, A. Klegeris, 2007, Current opinion in neurology.

Inflammation and insulin/IGF-1 resistance as the possible link between obesity and neurodegeneration

J. Little, A. Klegeris, L. J. Spielman, 2014, Journal of Neuroimmunology.

Globular adiponectin induces a pro-inflammatory response in human astrocytic cells.

J. Little, A. Klegeris, Z. Wan, 2014, Biochemical and biophysical research communications.

Cytochrome c can be released into extracellular space and modulate functions of human astrocytes in a toll-like receptor 4-dependent manner.

A. Klegeris, Tyler J. Wenzel, E. Bajwa, 2019, Biochimica et biophysica acta. General subjects.

Extracellular cytochrome c as an intercellular signaling molecule regulating microglial functions.

A. Klegeris, E. Bajwa, Ayden Gouveia, 2017, Biochimica et biophysica acta. General subjects.

The effects of voluntary wheel running on neuroinflammatory status: Role of monocyte chemoattractant protein-1

Sanjoy Ghosh, A. Klegeris, D. Gibson, 2017, Molecular and Cellular Neuroscience.

Pre-clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review

A. Mohamadkhani, A. Klegeris, M. Kosari, 2022, Frontiers in Aging Neuroscience.

Gold drug auranofin could reduce neuroinflammation by inhibiting microglia cytotoxic secretions and primed respiratory burst

S. Hashioka, A. Klegeris, J. Madeira, 2014, Journal of Neuroimmunology.

α-Synuclein activates stress signaling protein kinases in THP-1 cells and microglia

P. Mcgeer, E. Mcgeer, S. Pelech, 2008, Neurobiology of Aging.

Functional ryanodine receptors are expressed by human microglia and THP‐1 cells: Their possible involvement in modulation of neurotoxicity

Hyun B Choi, P. Mcgeer, A. Klegeris, 2007, Journal of neuroscience research.

Acetylcholinesterase activation of peritoneal macrophages is independent of catalytic activity

S. Greenfield, A. Klegeris, T. Budd, 1994, Cellular and Molecular Neurobiology.

Targeting neuroprotective functions of astrocytes in neuroimmune diseases

A. Klegeris, 2021, Expert opinion on therapeutic targets.

Microglial targets for effective therapies of Alzheimer’s disease

A. Klegeris, 2020, Frontiers in Drug, Chemistry and Clinical Research.

Metabolomics analysis implies noninvolvement of the kynurenine pathway neurotoxins in the interferon-gamma- induced neurotoxicity of adult human astrocytes

Hideyuki Suzuki, S. Hashioka, A. Klegeris, 2017 .

Incretin hormones regulate microglia oxidative stress, survival and expression of trophic factors.

A. Klegeris, D. Gibson, L. J. Spielman, 2017, European journal of cell biology.

The Role of Insulin and Incretins in Neuroinflammation and Neurodegeneration

A. Klegeris, L. J. Spielman, 2014 .

The involvement of glial cell-derived reactive oxygen and nitrogen species in Alzheimer’s disease

L. Lue, D. Walker, P. Mcgeer, 2001 .

Pathological proteins in senile plaques.

D. Walker, P. Mcgeer, E. Mcgeer, 1994, The Tohoku journal of experimental medicine.

Effect of cytotoxic dusts on formation of active forms of oxygen by rat peritoneal macrophages

A. Klegeris, S. Soodaeva, L. Korkina, 1991, Bulletin of Experimental Biology and Medicine.

Policing the Police: Astrocytes Modulate Microglial Activation

Ping Li, C. Cowan, A. Klegeris, 2006, The Journal of Neuroscience.

Acetaminophen metabolites p-aminophenol and AM404 inhibit microglial activation

A. Klegeris, Wyatt T. Slattery, 2018 .

The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation.

J. Little, A. Klegeris, J. Madeira, 2012, Journal of Alzheimer's disease : JAD.

Acetylcholinesterase-induced respiratory burst in macrophages: evidence for the involvement of the macrophage mannose-fucose receptor.

S. Greenfield, A. Klegeris, T. Budd, 1996, Biochimica et biophysica acta.

The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ

P. Mcgeer, A. Klegeris, 2012, Journal of Neuroinflammation.

Severe vascular disturbance in a case of familial brain calcinosis

J. Miklossy, Z. Wszolek, P. Mcgeer, 2005, Acta Neuropathologica.

Potential neurotoxic activity of diverse molecules released by astrocytes

A. Klegeris, Anna K. Bernath, C. Richards, 2022, Brain Research Bulletin.

Extracellular cardiolipin modulates microglial phagocytosis and cytokine secretion in a toll-like receptor (TLR) 4-dependent manner

A. Klegeris, Tyler J. Wenzel, Athena L. Ranger, 2021, Journal of Neuroimmunology.

High Glucose Enhances Neurotoxicity and Inflammatory Cytokine Secretion by Stimulated Human Astrocytes.

J. Little, A. Klegeris, Manpreet Bahniwal, 2017, Current Alzheimer research.

Proton pump inhibitors reduce interferon‐γ‐induced neurotoxicity and STAT3 phosphorylation of human astrocytes

P. Mcgeer, S. Hashioka, A. Klegeris, 2011, Glia.

Interaction of various intracellular signaling mechanisms involved in mononuclear phagocyte toxicity toward neuronal cells

P. Mcgeer, A. Klegeris, Patrick L. McGeer, 2000, Journal of leukocyte biology.

Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants

P. Mcgeer, A. Klegeris, 1994, Journal of Neuroimmunology.

A new look at auranofin, dextromethorphan and rosiglitazone for reduction of glia-mediated inflammation in neurodegenerative diseases

A. Klegeris, J. Madeira, Stephanie M. Schindler, 2015, Neural regeneration research.

Differential expression of interferon-γ receptor on human glial cells in vivo and in vitro

P. Mcgeer, S. Hashioka, A. Klegeris, 2010, Journal of Neuroimmunology.

Interferon-γ-dependent cytotoxic activation of human astrocytes and astrocytoma cells

P. Mcgeer, S. Hashioka, A. Klegeris, 2009, Neurobiology of Aging.

Dynamic changes in metabolites of the kynurenine pathway in Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease: A systematic Review and meta-analysis

A. Klegeris, F. Sayehmiri, M. Fathi, 2022, Frontiers in Immunology.

Inhibition of respiratory burst in macrophages by complement receptor blockade.

P. Mcgeer, A. Klegeris, 1994, European journal of pharmacology.

Antitumor activity of asukamycin, a secondary metabolite from the actinomycete bacterium Streptomyces nodosus subspecies asukaensis.

A. Klegeris, P. Shipley, C. Le, 2009, International journal of molecular medicine.

Insulin Modulates In Vitro Secretion of Cytokines and Cytotoxins by Human Glial Cells.

D. Walker, J. Little, A. Klegeris, 2015, Current Alzheimer research.

Immune mechanism in senile plaque formation

D. Walker, P. Mcgeer, E. Mcgeer, 1994 .

Resolution-Associated Molecular Patterns (RAMPs) as Endogenous Regulators of Glia Functions in Neuroinflammatory Disease.

A. Klegeris, Tyler J. Wenzel, E. Bajwa, 2020, CNS & neurological disorders drug targets.

Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease.

P. Mcgeer, A. Klegeris, 2005, Current Alzheimer research.

Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers

P. Mcgeer, S. Hashioka, A. Klegeris, 2012, Neuropharmacology.

Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells

G. Lambeau, J. Little, A. Klegeris, 2012, Molecular and Cellular Neuroscience.

Adhesion of exogenous human microglia and THP-1 cells to amyloid plaques of postmortem Alzheimer's disease brain.

J. Miklossy, P. Mcgeer, S. Hashioka, 2008, Journal of Alzheimer's disease : JAD.

Extracellular histones as damage-associated molecular patterns in neuroinflammatory responses

A. Klegeris, C. Richards, Athena L. Ranger, 2022, Reviews in the neurosciences.

The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production

A. Klegeris, Tyler J. Wenzel, T. Murray, 2020, Molecular and Cellular Neuroscience.

Regulation of neuroimmune processes by damage- and resolution-associated molecular patterns

A. Klegeris, 2020, Neural regeneration research.

Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis.

A. Klegeris, D. Gibson, Ellen J. Gates, 2021, Biochimica et biophysica acta. Molecular basis of disease.

Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity

A. Klegeris, F. Ménard, Edward G. Neeland, 2019, Cells.

Synthesis and biological evaluation of novel pyrazole compounds.

A. Klegeris, B. Patrick, A. Abd-El-Aziz, 2010, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents.

A. Klegeris, I. M. El-Ashmawy, E. Villanueva, 2010, Bioorganic & medicinal chemistry.

Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha.

D. Walker, P. Mcgeer, A. Klegeris, 1997, Brain research.

Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review

A. Mohamadkhani, A. Klegeris, F. Sayehmiri, 2022, Frontiers in Immunology.

The synthesis and characterization of a series of cobalt(II) β-ketoaminato complexes and their cytotoxic activity towards human tumor cell lines.

A. Klegeris, N. Beloukhina, Kalun Boudreau, 2011, Journal of inorganic biochemistry.

Dynamics of undergraduate student generic problem-solving skills captured by a campus-wide study

A. Klegeris, H. Hurren, Manpreet Bahniwal, 2016, Higher Education.

Anti-inflammatory effects of cerebrocrast in a model of rat paw edema and on mononuclear THP-1 cells.

P. Mcgeer, A. Klegeris, G. Duburs, 2002, European journal of pharmacology.

The biological activity of auranofin: implications for novel treatment of diseases

A. Klegeris, D. Gibson, W. Kean, 2012, Inflammopharmacology.

In silico design of novel gold-phosphate containing compounds as selective inhibitors of cathepsin B in neuroinflammation

A. Klegeris, M. Sharifi, Alexsey V. Raevsky, 2018, Neuroimmunology and Neuroinflammation.

Effects of C‐reactive protein and pentosan polysulphate on human complement activation

P. Mcgeer, A. Klegeris, E. Singh, 2002, Immunology.

Emerging roles of microglial cathepsins in neurodegenerative disease

A. Klegeris, Jessica R. Lowry, 2018, Brain Research Bulletin.

Inflammation in transgenic mouse models of neurodegenerative disorders.

P. Mcgeer, A. Klegeris, C. Schwab, 2010, Biochimica et biophysica acta.

Characterization of novel kainic acid analogs as inhibitors of select microglial functions

A. Klegeris, F. Ménard, Zhenlin Tian, 2019, European journal of pharmacology.

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

A. Klegeris, Ellen J. Gates, Tyler J. Wenzel, 2020, Molecular and Cellular Neuroscience.

Toxicity of Human Monocytic Thp-1 Cells and Microglia toward Sh-sy5y Neuroblastoma Cells Is Reduced by Inhibitors of 5-lipoxygenase and Its Activating Protein Flap

P. Mcgeer, A. Klegeris, Patrick L. McGeer, 2022 .

Inflammation, the complement system and the diseases of aging

P. Mcgeer, E. Mcgeer, A. Klegeris, 2005, Neurobiology of Aging.

Microparticles: A New Perspective in Central Nervous System Disorders

J. Little, A. Klegeris, Stephanie M. Schindler, 2014, BioMed research international.

Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer’s disease

A. Klegeris, E. Bajwa, 2022, Neural regeneration research.

Novel multi‐target directed ligand‐based strategies for reducing neuroinflammation in Alzheimer's disease

A. Klegeris, Tyler J. Wenzel, 2018, Life sciences.

Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases

A. Klegeris, D. Gibson, L. J. Spielman, 2018, Neurochemistry International.

Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells

P. Mcgeer, A. Klegeris, D. Walker, 1997, Journal of Neuroimmunology.

Therapeutic potential of cannabinoids in the treatment of neuroinflammation associated with Parkinson's disease.

J. Little, A. Klegeris, E. Villanueva, 2011, Mini reviews in medicinal chemistry.

Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid‐type CB2 receptor

P. Mcgeer, A. Klegeris, C. J. Bissonnette, 2003, British journal of pharmacology.

Induction of complement C9 messenger RNAs in human neuronal cells by inflammatory stimuli: relevance to neurodegenerative disorders

P. Mcgeer, A. Klegeris, C. Schwab, 2001, Experimental Gerontology.

β‐Amyloid protein enhances macrophage production of oxygen free radicals and glutamate

P. Mcgeer, A. Klegeris, Patrick L. McGeer, 1997 .

LRRK2 Expression in Normal and Pathologic Human Brain and in Human Cell Lines

Tetsuaki Arai, Patrick L. McGeer, Andis Klegeris, 2006, Journal of neuropathology and experimental neurology.

Microglia secrete distinct sets of neurotoxins in a stimulus-dependent manner

A. Klegeris, J. Gibon, Anna K. Bernath, 2023, Brain Research.

Glia-Driven Neuroinflammation and Systemic Inflammation in Alzheimer’s Disease

S. Hashioka, A. Klegeris, Zhou Wu, 2020, Current neuropharmacology.

Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner

A. Klegeris, J. Gibon, Tyler J. Wenzel, 2022, Mediators of inflammation.

STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes

H. Qing, P. Mcgeer, S. Hashioka, 2011, Neurobiology of Disease.

Expression of complement messenger RNAs by human endothelial cells

P. Mcgeer, A. Klegeris, K. Dorovini‐Zis, 2000, Brain Research.

Activation of Macrophages by Alzheimer β Amyloid Peptide

D. Walker, P. Mcgeer, A. Klegeris, 1994 .

Activation of macrophages by Alzheimer beta amyloid peptide.

D. Walker, P. Mcgeer, A. Klegeris, 1994, Biochemical and biophysical research communications.

Actions of the anti-angiogenic compound angiostatin in an animal model of Alzheimer's disease.

J. Ryu, J. Little, A. Klegeris, 2013, Current Alzheimer research.

Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs

P. Mcgeer, A. Klegeris, M. Hosokawa, 2004, Journal of Neuroinflammation.

Expression of complement messenger RNAs and proteins by human oligodendroglial cells

P. Mcgeer, A. Klegeris, J. Maguire, 2003, Glia.

Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes

Hyun B Choi, P. Mcgeer, S. Hashioka, 2014, BMC Neuroscience.

Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes

P. Mcgeer, S. Hashioka, J. Little, 2014, BMC Neuroscience.

Modifiable risk factors of Alzheimer's disease and neuroinflammation: what are the links?

A. Klegeris, Caitlin B. Pointer, E. Bajwa, 2016 .

Elucidating the link between the modifiable risk factors of Alzheimer's disease and neuroinflammation.

A. Klegeris, Stephanie M. Schindler, 2016, Neurodegenerative disease management.

Physical activity and exercise attenuate neuroinflammation in neurological diseases

J. Little, A. Klegeris, L. J. Spielman, 2016, Brain Research Bulletin.

Complement activation by islet amyloid polypeptide (IAPP) and α-synuclein 112

P. Mcgeer, A. Klegeris, 2007 .

Complement activation by islet amyloid polypeptide (IAPP) and alpha-synuclein 112.

P. Mcgeer, A. Klegeris, 2007, Biochemical and biophysical research communications.

Increase in Core Body Temperature of Alzheimer’s Disease Patients as a Possible Indicator of Chronic Neuroinflammation: A Meta-Analysis

P. Mcgeer, A. Klegeris, M. Schulzer, 2006, Gerontology.

Neuroinflammation as a Common Mechanism Associated with the Modifiable Risk Factors for Alzheimer's and Parkinson's Diseases.

A. Klegeris, Caitlin B. Pointer, L. J. Spielman, 2017, Current aging science.

Toxicity of human THP-1 monocytic cells towards neuron-like cells is reduced by non-steroidal anti-inflammatory drugs (NSAIDs)

D. Walker, P. Mcgeer, A. Klegeris, 1999, Neuropharmacology.

S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP-1 cell neurotoxicity

P. Mcgeer, A. Klegeris, J. Maguire, 2004, Journal of Neuroimmunology.

Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxam ide (PK 11195) on some mononuclear phagocyte functions.

P. Mcgeer, E. Mcgeer, A. Klegeris, 2000, Biochemical pharmacology.

Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α

D. Walker, P. Mcgeer, A. Klegeris, 1997, Brain Research.

Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders

A. Klegeris, Ellen J. Gates, Tyler J. Wenzel, 2019, Expert opinion on therapeutic targets.

Possible role of microparticles in neuroimmune signaling of microglial cells

J. Little, A. Klegeris, E. Bajwa, 2016 .

Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system

P. Mcgeer, A. Klegeris, C. J. Bissonnette, 2005, Neurobiology of Aging.

PROBLEM-BASED LEARNING IN A LARGE CLASSROOM SETTING: METHODOLOGY, STUDENT PERCEPTION AND PROBLEM-SOLVING SKILLS

A. Klegeris, H. Hurren, 2011 .

Cardiolipin in Central Nervous System Physiology and Pathology

A. Klegeris, Caitlin B. Pointer, 2017, Cellular and Molecular Neurobiology.

Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia

D. Walker, J. Little, A. Klegeris, 2014, Molecular and Cellular Neuroscience.

Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity

P. Mcgeer, S. Hashioka, A. Klegeris, 2009, Experimental Neurology.

Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status, and ion transporter gene expression.

Sanjoy Ghosh, S. Halder, A. Klegeris, 2011, American journal of physiology. Gastrointestinal and liver physiology.

The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation

A. Klegeris, Caitlin B. Pointer, E. Bajwa, 2019, Mediators of inflammation.

Potential neurotoxic activity of diverse molecules released by microglia

A. Klegeris, C. Richards, T. Murray, 2021, Neurochemistry International.

The subthalamo-nigral pathway regulates movement and concomitant acetylcholinesterase release from the substantia nigra

S. Greenfield, B. Dickie, A. Klegeris, 2005, Journal of Neural Transmission / General Section JNT.

Chymotrypsin‐like proteases contribute to human monocytic THP‐1 cell as well as human microglial neurotoxicity

P. Mcgeer, A. Klegeris, 2005, Glia.

Interleukin 1α and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage

P. Mcgeer, E. Mcgeer, A. Klegeris, 2004, Neuroscience Letters.

Mitochondrial transcription factor a (TFAM): a novel brain intercellular signaling molecule and microglial activator

J. Little, A. Klegeris, Stephanie M. Schindler, 2014 .

Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)

D. Mousseau, A. Klegeris, J. Gibon, 2022, Molecular and Cellular Neuroscience.

The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ

P. Mcgeer, S. Hashioka, A. Klegeris, 2012, Journal of Neuroinflammation.

Novel protective properties of auranofin: inhibition of human astrocyte cytotoxic secretions and direct neuroprotection.

S. Hashioka, A. Klegeris, D. Gibson, 2013, Life sciences.

Moderate increase in temperature may exacerbate neuroinflammatory processes in the brain: Human cell culture studies

A. Klegeris, Manpreet Bahniwal, E. Villanueva, 2011, Journal of Neuroimmunology.

Inflammatory cytokine levels are influenced by interactions between THP-1 monocytic, U-373 MG astrocytic, and SH-SY5Y neuronal cell lines of human origin

P. Mcgeer, A. Klegeris, 2001, Neuroscience Letters.

The biological activity of auranofin: implications for novel treatment of diseases

A. Klegeris, D. Gibson, W. Kean, 2012, Inflammopharmacology.

LACK OF CORRELATION BETWEEN DISTINCT UNIVERSITY S TUDENT SKILL SETS IDENTIFIED BY USING A PANEL OF ASSESSMENTS: A TWO YEAR STUDY

A. Klegeris, H. Hurren, Manpreet Bahniwal, 2012 .

Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide.

Takahiro A. Kato, S. Kanba, P. Mcgeer, 2007, Experimental neurology.

Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP‐1 cell neurotoxicity

P. Mcgeer, Sheng Pan, S. Hashioka, 2008, Glia.

Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity

Andis Klegeris, P. Mcgeer, A. Klegeris, 2002, Neurobiology of Aging.

Pattern recognition receptors mediate pro-inflammatory effects of extracellular mitochondrial transcription factor A (TFAM)

S. Maier, A. Klegeris, M. Frank, 2018, Molecular and Cellular Neuroscience.

The relationship between visual stimulation, behaviour and continous release of protein in the substantia nigra

S. Greenfield, A. Klegeris, S. Jones, 1991, Brain Research.

Regulation of the phagocytic activity of astrocytes by neuroimmune mediators endogenous to the central nervous system

A. Klegeris, J. Gibon, Svetlana Simtchouk, 2023, PloS one.

A possible interaction between acetylcholinesterase and dopamine molecules during autoxidation of the amine.

S. Greenfield, A. Klegeris, L. Korkina, 1995, Free radical biology & medicine.

Toxicity of human monocytic THP‐1 cells and microglia toward SH‐SY5Y neuroblastoma cells is reduced by inhibitors of 5‐lipoxygenase and its activating protein FLAP

P. Mcgeer, A. Klegeris, 2003, Journal of leukocyte biology.

beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate.

P. Mcgeer, A. Klegeris, 1997, Journal of Neuroscience Research.

Mixed-mode instruction using active learning in small teams improves generic problem-solving skills of university students

A. Klegeris, 2020 .