H. Land

发表

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1

A Sewing, A C Lloyd, A. Lloyd, 1997, Molecular and cellular biology.

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Robert A. Weinberg, Hartmut Land, R. Weinberg, 1983, Nature.

Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype

A. Yakovlev, L. Klebanov, H. McMurray, 2008, Nature.

New Limitation Change to Approved for Public Release, Distribution Unlimited from Authority Signalling Pathways of Cooperative Oncogenes and Their Damd17-93-j-3033 Effects on the Transcriptional Control of Cell Cycle Genes in Schwann Cell Transformation (neurofibromatosis)

H. Land, P. Rinehart, 2022 .

C-MYC: evidence for multiple regulatory functions.

L. Penn, H. Land, E. M. Laufer, 1990, Seminars in cancer biology.

Integrated control of cell proliferation and cell death by the c-myc oncogene.

G. Evan, A. Fanidi, B. Amati, 1994, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Gene network modeling via TopNet reveals robust epistatic interactions between functionally diverse tumor critical mediator genes

M. McCall, H. Stern, H. McMurray, 2020, bioRxiv.

Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts.

R. Weinberg, L. Parada, H. Land, 1985, Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale.

Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression.

A. Hezel, H. Land, C. Kinsey, 2014, Cell reports.

5'-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency.

H. Hauser, G. Schütz, H. Land, 1981, Nucleic acids research.

Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.

A. Zhu, A. Hezel, N. Bardeesy, 2012, Cancer research.

Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.

A. Zhu, A. Hezel, N. Bardeesy, 2012, Cancer research.

Activated oncogenes in Burkitt's lymphoma.

R. Weinberg, J. Cunningham, G. Lenoir, 1984, Current topics in microbiology and immunology.

Deduced amino acid sequence from the bovine oxytocin–neurophysin I precursor cDNA

G. Schütz, H. Land, M. Grez, 1983, Nature.

Oncogenes Cooperate, but How?

H. Land, 1986 .

Choice and manipulation of retroviral vectors.

H. Land, J. Morgenstern, 1991, Methods in molecular biology.

The isolation and characterization of the chicken lysozyme and ovomucoid gene.

A. E. Sippel, H. Hauser, G. Schütz, 1980, Journal of steroid biochemistry.

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.

H. Land, J. Morgenstern, 1990, Nucleic acids research.

Recruitment of TRRAP required for oncogenic transformation by E1A

B. Amati, K. Alevizopoulos, H. Land, 2001, Oncogene.

Expression of cyclin D1 mRNA is not upregulated by Myc in rat fibroblasts.

M. Eilers, A. Philipp, H. Land, 1995, Oncogene.

Induction of apoptosis in fibroblasts by c-myc protein

Gerard I. Evan, Hartmut Land, Linda Z. Penn, 1992, Cell.

Chicken lysozyme gene contains several intervening sequences.

A. E. Sippel, B. Groner, G. Schütz, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Cellular oncogenes and multistep carcinogenesis.

R. Weinberg, L. Parada, H. Land, 1983, Science.

On non-detects in qPCR data

Matthew N. McCall, Anthony Almudevar, Helene R. McMurray, 2014, Bioinform..

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

V. Rotter, R. Weinberg, D. Wolf, 1984, Nature.

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells.

H. Land, J. Morgenstern, Jay P. Morgenstern, 1990, Nucleic acids research.

Anticancer activity of the cholesterol exporter ABCA1 gene.

H. Land, Bradley Smith, 2012, Cell reports.

The c‐Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

G. Evan, T. Littlewood, B. Amati, 1993, The EMBO journal.

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

G. Evan, T. Littlewood, B. Amati, 1992, Nature.

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility

Hartmut Land, Mingxuan Xia, H. Land, 2007, Nature Structural &Molecular Biology.

Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery

H. McMurray, H. Land, E. Sampson, 2013, Oncogene.

Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

John M. Ashton, B. Ebert, D. Root, 2012, Cell stem cell.

Cyclins D1 and D2 mediate Myc‐induced proliferation via sequestration of p27Kip1 and p21Cip1

A. Sewing, H. Land, B. Griffiths, 1999, The EMBO journal.

Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers.

B. Amati, H. Land, H Land, 1993, Nucleic acids research.

Oncogenic activity of the c-Myc protein requires dimerization with Max

Bruno Amati, Gerard I. Evan, Hartmut Land, 1993, Cell.

Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping

G. Evan, T. Littlewood, L. Penn, 1990, Molecular and cellular biology.

Negative autoregulation of c‐myc transcription.

L. Penn, H. Land, M. Brooks, 1990, The EMBO journal.

Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death.

B. Amati, H. Land, H Land, 1994, Current opinion in genetics & development.

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27Kip1 binding to newly formed complexes

Andreas Sewing, Hartmut Land, A. Sewing, 1997, Oncogene.

[3] Transformation of primary rat embryo cells

H. Land, 1995 .

Transformation of primary rat embryo cells.

H. Land, 1995, Methods in enzymology.

Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ

J. Southgate, T. Thompson, H. Land, 1989, Cell.

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

A. Lloyd, M. McMahon, H. Land, 1997, Genes & development.

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts

R. Weinberg, L. Parada, H. Land, 1986, Molecular and cellular biology.

Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

A. Hezel, S. Mello, P. Vertino, 2022, Cell reports.

[20] Synthesis of ds-cDNA involving addition of dCMP tails to allow cloning of 5′-terminal mRNA sequences

H. Hauser, G. Schütz, H. Land, 1983 .

Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells

H. Land, Bradley Smith, J. Munger, 2016, Cell reports.

Multiple mRNAs are generated from the chicken lysozyme gene

A. E. Sippel, G. Schütz, H. Land, 1981, Cell.

Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth

H. Land, Amy Tsurumi, P. Dutta, 2013, Proceedings of the National Academy of Sciences.

The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors.

R. Jaenisch, P. Baldacci, T. Thompson, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin–neurophysin II precursor

G. Schütz, H. Land, D. Richter, 1982, Nature.

The Birt-Hogg-Dubé tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis.

H. Land, Guan Wu, Amy Tsurumi, 2013, Human molecular genetics.

Immortalization and transformation are associated with specific alterations in choline metabolism.

S. Williams, M. Noble, H. Land, 1996, Cancer research.

A four gene signature predictive of recurrent prostate cancer

Wiam Bshara, Carl Morrison, James L Mohler, 2016, Oncotarget.

Max and c-Myc/Max DNA-binding activities in cell extracts.

G. Evan, T. Littlewood, B. Amati, 1992, Oncogene.

Cloning of chicken lysozyme structural gene sequences synthesized in vitro.

A. E. Sippel, G. Schütz, H. Land, 1978, Nucleic acids research.

Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline

J. Friedberg, R. Deshaies, H. Land, 2015, Oncotarget.

Synthesis of ds-cDNA involving addition of dCMP tails to allow cloning of 5'-terminal m RNA sequences.

H. Hauser, G. Schütz, H. Land, 1983, Methods in Enzymology.

Statistical Approaches to Decreasing the Discrepancy of Non-detects in qPCR Data

Matthew N. McCall, Tanzy Love, Helene R. McMurray, 2017, bioRxiv.

Establishment of rat endometrial cell lines by retroviral mediated transfer of immortalizing and transforming oncogenes.

M. Beato, H. Land, G. Helftenbein, 1990, Oncogene.

p19ARF‐independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

F. Watt, H. Land, W. Weinberg, 2001, EMBO reports.

Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes

H. Stern, H. McMurray, H. Land, 2021, Cell reports.

Fitting Boolean Networks from Steady State Perturbation Data

Anthony Almudevar, Hartmut Land, Matthew N. McCall, 2011, Statistical applications in genetics and molecular biology.

Ras‐mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation.

M. Noble, M. Noble, A. Ridley, 1988, The EMBO journal.

An in situ transgenic enzyme marker for the midgestation mouse embryo and the visualization of inner cell mass clones during early organogenesis.

R. Beddington, H. Land, A. Hogan, 1989, Development.

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

O. Bogler, M. Noble, H. Land, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and characterization of the chicken ovomucoid gene.

A. E. Sippel, R. Lurz, G. Schütz, 1979, Nucleic Acids Research.

Structure of the lysozyme gene and expression in the oviduct and macrophages.

T. Graf, H. Beug, H. Hauser, 1981, Haematology and blood transfusion.

Transforming growth factors-beta 1 and beta 2 are mitogens for rat Schwann cells

A. Ridley, H. Land, P. Stroobant, 1989, The Journal of cell biology.

Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.

A. Zhu, A. Hezel, N. Bardeesy, 2012, Cancer research.