B. Campanini

发表

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

F. Spyrakis, B. Luisi, L. Lazzarato, 2022, Proceedings of the National Academy of Sciences of the United States of America.

The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase.

F. Spyrakis, A. Mozzarelli, S. Bettati, 2011, Biochimica et biophysica acta.

Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor.

S. Pascarella, S. Maggi, S. Bettati, 2017, Biochimica et biophysica acta. General subjects.

Moonlighting O-acetylserine sulfhydrylase: New functions for an old protein.

A. Mozzarelli, C. Hayes, S. Bettati, 2015, Biochimica et biophysica acta.

Interaction of serine acetyltransferase with O‐acetylserine sulfhydrylase active site: Evidence from fluorescence spectroscopy

A. Mozzarelli, S. Bettati, P. Cook, 2005, Protein science : a publication of the Protein Society.

Iron Metabolism at the Interface between Host and Pathogen: From Nutritional Immunity to Antibacterial Development

F. Spyrakis, L. Ronda, S. Bettati, 2020, International journal of molecular sciences.

Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action

A. Mozzarelli, L. Ronda, S. Bettati, 2019, International journal of molecular sciences.

Enhanced Green Fluorescent Protein (GFP) fluorescence after polyelectrolyte caging.

S. Krol, A. Diaspro, B. Campanini, 2006, Optics express.

A Novel Assay for Phosphoserine Phosphatase Exploiting Serine Acetyltransferase as the Coupling Enzyme

S. Bettati, A. Peracchi, B. Campanini, 2021, Life.

Green fluorescent protein ground states: the influence of a second protonation site near the chromophore.

W. Rocchia, F. Beltram, C. Viappiani, 2007, Biochemistry.

Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant.

A. Mozzarelli, S. Bettati, Marialaura Marchetti, 2021, ACS infectious diseases.

Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight

F. J. Luque, F. Spyrakis, S. Cannistraro, 2019, Scientific Reports.

Expanding the chemical space of human serine racemase inhibitors.

F. Spyrakis, G. Cruciani, A. Mozzarelli, 2015, Bioorganic & medicinal chemistry letters.

Evidence of discrete substates and unfolding pathways in green fluorescent protein.

G. Baldini, A. Mozzarelli, S. Bettati, 2007, Biophysical journal.

Stimulated emission properties of fluorophores by CW-STED single molecule spectroscopy.

G. Cerullo, B. Campanini, L. Sironi, 2013, The journal of physical chemistry. B.

Exploring the chemical space around N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide, a hit compound with Serine Acetyltransferase (SAT) inhibitory properties

E. Carosati, S. Bettati, Marialaura Marchetti, 2022, Results in Chemistry.

Effect of the point mutation H148G on GFPmut2 unfolding kinetics by fluorescence spectroscopy.

S. Bettati, B. Campanini, G. Chirico, 2011, Biophysical chemistry.

Birth of a pathway for sulfur metabolism in early amniote evolution

P. Antin, A. Peracchi, B. Campanini, 2020, Nature Ecology & Evolution.

Revealing the Dynamic Allosteric Changes Required for Formation of the Cysteine Synthase Complex by Hydrogen-Deuterium Exchange MS

S. Bettati, Eleanor R Dickinson, Marialaura Marchetti, 2021, Molecular & cellular proteomics : MCP.

Off to a slow start: Analyzing lag phases and accelerating rates in steady-state enzyme kinetics.

L. Ronda, A. Peracchi, B. Campanini, 2020, Analytical biochemistry.

Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

S. Bettati, Marialaura Marchetti, B. Campanini, 2022, Pharmaceuticals.

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

A. Mozzarelli, A. Jirgensons, S. Bettati, 2018, Journal of Enzyme Inhibition and Medicinal Chemistry.

A Two-step Process Controls the Formation of the Bienzyme Cysteine Synthase Complex*

A. Mozzarelli, S. Bettati, P. Cook, 2010, The Journal of Biological Chemistry.

Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives

A. Mozzarelli, A. Jirgensons, B. Campanini, 2018, Journal of enzyme inhibition and medicinal chemistry.

Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor.

A. Mozzarelli, S. Bettati, B. Campanini, 2020, ACS medicinal chemistry letters.

Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

A. Mozzarelli, S. Bettati, B. Campanini, 2016, Journal of enzyme inhibition and medicinal chemistry.

Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A.

A. Mozzarelli, S. Bettati, P. Cook, 2010, Biochemistry.

Rational Design, Synthesis, and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O-Acetylserine Sulfhydrylase.

A. Mozzarelli, S. Bettati, B. Campanini, 2016, Journal of medicinal chemistry.

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

A. Mozzarelli, S. Bettati, A. Peracchi, 2014, Amino Acids.

Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase

A. Mozzarelli, B. Campanini, G. Costantino, 2012 .

Pyridoxal 5′-Phosphate-Dependent Enzymes: Catalysis, Conformation, and Genomics

F. Spyrakis, Alessio Amadasi, A. Mozzarelli, 2010 .

Singlet oxygen photosensitisation by GFP mutants: oxygen accessibility to the chromophore

C. Viappiani, S. Abbruzzetti, B. Campanini, 2010, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes.

A. Mozzarelli, P. Burkhard, S. Bettati, 2007, Biochemistry.

Green Fluorescent Protein Photodynamics as a Tool for Fluorescence Correlative Studies and Applications

B. Campanini, G. Chirico, M. Collini, 2011 .

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design

M. Welch, A. Mozzarelli, A. Jirgensons, 2018, Journal of enzyme inhibition and medicinal chemistry.

Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase

A. Mozzarelli, C. Hayes, S. Bettati, 2017, Scientific Reports.

More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function

A. Mozzarelli, C. Viappiani, S. Abbruzzetti, 2019 .

Human kynurenine aminotransferase II – reactivity with substrates and inhibitors

A. Mozzarelli, F. Rossi, M. Rizzi, 2011, The FEBS journal.

A Competitive O-Acetylserine Sulfhydrylase Inhibitor Modulates the Formation of Cysteine Synthase Complex

A. Mozzarelli, S. Cannistraro, L. Ronda, 2021, Catalysts.

Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex

A. Mozzarelli, C. Hayes, S. Bettati, 2017, FEBS letters.

Structural insight into the interaction of O‐acetylserine sulfhydrylase with competitive, peptidic inhibitors by saturation transfer difference‐NMR

F. Spyrakis, A. Mozzarelli, S. Bettati, 2016, FEBS letters.

Isozyme-Specific Ligands for O-acetylserine sulfhydrylase, a Novel Antibiotic Target

Pietro Cozzini, Francesca Spyrakis, Paolo Benedetti, 2013, PloS one.

Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase.

Pietro Cozzini, Glen E Kellogg, Francesca Spyrakis, 2013, Biochimica et biophysica acta.

Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy.

A. Mozzarelli, S. Bettati, P. Cook, 2011, Archives of biochemistry and biophysics.

Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature.

Alexander S. Bayden, F. Spyrakis, Alessio Amadasi, 2010, Journal of medicinal chemistry.

Surface-exposed Tryptophan Residues Are Essential for O-Acetylserine Sulfhydrylase Structure, Function, and Stability*

A. Mozzarelli, S. Bettati, P. Cook, 2003, Journal of Biological Chemistry.

Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence.

E. Gratton, A. Mozzarelli, S. Bettati, 2002, Biochimica et biophysica acta.

Role of Pyridoxal 5′-Phosphate in the Structural Stabilization of O-Acetylserine Sulfhydrylase*

E. Gratton, A. Mozzarelli, S. Bettati, 2000, The Journal of Biological Chemistry.

Functional properties of immobilized pyridoxal 5’-phosphate-dependent enzymes probed by absorption microspectrophotometry

A. Mozzarelli, S. Bettati, A. Peracchi, 2000 .

Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives.

A. Mozzarelli, B. Campanini, S. Bruno, 2016, The Biochemical journal.

The Energy Landscape of Human Serine Racemase

A. Mozzarelli, Marialaura Marchetti, B. Campanini, 2019, Front. Mol. Biosci..

Immobilization of Proteins in Silica Gel: Biochemical and Biophysical Properties

A. Mozzarelli, C. Viappiani, S. Abbruzzetti, 2015 .

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

A. Mozzarelli, S. Bettati, A. Peracchi, 2014, Amino Acids.

Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders

A. Mozzarelli, B. Campanini, S. Bruno, 2003 .

A novel Bim-BH3-derived Bcl-XL inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity

R. Pesenti, G. Damonte, L. Tortolina, 2008, Cell cycle.

Birth of a pathway for sulfur metabolism in early amniote evolution

P. Antin, A. Peracchi, B. Campanini, 2020, Nature Ecology & Evolution.

ATP binding to human serine racemase is cooperative and modulated by glycine

A. Mozzarelli, A. Peracchi, Marialaura Marchetti, 2013, The FEBS journal.

Protonation and conformational dynamics of GFP mutants by two-photon excitation fluorescence correlation spectroscopy.

G. Baldini, S. Bettati, B. Campanini, 2008, The journal of physical chemistry. B.

Role of histidine 148 in stability and dynamics of a highly fluorescent GFP variant.

S. Bettati, B. Campanini, G. Chirico, 2013, Biochimica et biophysica acta.

Tracking unfolding and refolding of single GFPmut2 molecules.

A. Diaspro, A. Mozzarelli, S. Bettati, 2005, Biophysical journal.

Unfolding of Green Fluorescent Protein mut2 in wet nanoporous silica gels

A. Mozzarelli, S. Bettati, B. Campanini, 2005, Protein science : a publication of the Protein Society.

Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form.

A. Mozzarelli, L. Ronda, B. Campanini, 2017, Biochimica et biophysica acta. Proteins and proteomics.

Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase.

A. Mozzarelli, S. Bettati, B. Campanini, 2020, Biochimica et biophysica acta. Proteins and proteomics.

Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution

A. Mozzarelli, S. Bettati, B. Campanini, 2013, BioMed research international.

Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP

A. Mozzarelli, S. Bettati, Marialaura Marchetti, 2018, Scientific Reports.

Kinetics of acid-induced spectral changes in the GFPmut2 chromophore.

A. Mozzarelli, C. Viappiani, S. Abbruzzetti, 2005, Journal of the American Chemical Society.

L‐serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase

A. Mozzarelli, G. Murtas, L. Pollegioni, 2023, Protein science : a publication of the Protein Society.

Dynamics of green fluorescent protein mutant2 in solution, on spin‐coated glasses, and encapsulated in wet silica gels

A. Diaspro, A. Mozzarelli, S. Bettati, 2002, Protein science : a publication of the Protein Society.

Human serine racemase is nitrosylated at multiple sites.

A. Mozzarelli, B. Campanini, S. Bruno, 2018, Biochimica et biophysica acta. Proteins and proteomics.

Single amino acid replacement makes Aequorea victoria fluorescent proteins reversibly photoswitchable.

F. Beltram, C. Viappiani, S. Abbruzzetti, 2010, Journal of the American Chemical Society.

Structure and single crystal spectroscopy of Green Fluorescent Proteins.

S. Bettati, B. Campanini, R. Battistutta, 2011, Biochimica et biophysica acta.

The allosteric interplay between S‐nitrosylation and glycine binding controls the activity of human serine racemase

F. Spyrakis, A. Mozzarelli, S. Bettati, 2020, The FEBS journal.

GFP-mut2 proteins in trehalose-water matrixes: spatially heterogeneous protein-water-sugar structures.

G. Cottone, L. Cordone, B. Campanini, 2007, Biophysical journal.

Sulfur Mobilization in Cyanobacteria

A. Mozzarelli, S. Abbruzzetti, B. Campanini, 2006, Journal of Biological Chemistry.

Voltage regulation of single green fluorescent protein mutants.

S. Krol, A. Diaspro, B. Campanini, 2007, Biophysical chemistry.

The human phosphorylated pathway: a multienzyme metabolic assembly for l‐serine biosynthesis

A. Mozzarelli, G. Murtas, L. Pollegioni, 2023, The FEBS journal.

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

A. Mozzarelli, S. Bettati, B. Campanini, 2021, Pharmaceuticals.

Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets

Marco Pieroni, Gabriele Costantino, Agostino Bruno, 2018, J. Chem. Inf. Model..

Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase

A. Mozzarelli, C. Hayes, S. Bettati, 2017, Scientific Reports.

Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy.

A. Mozzarelli, S. Bettati, B. Campanini, 2014, Current medicinal chemistry.

Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography.

A. Mozzarelli, L. Ronda, S. Bettati, 2018, The journal of physical chemistry. B.

Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95

A. Mozzarelli, S. Bettati, B. Campanini, 2022, International journal of molecular sciences.

Structural stability of green fluorescent proteins entrapped in polyelectrolyte nanocapsules

S. Krol, A. Diaspro, B. Campanini, 2008, Journal of biophotonics.

Environment effects on the oscillatory unfolding kinetics of GFP

Giuseppe Chirico, Fabio Cannone, Andrea Mozzarelli, 2007, European Biophysics Journal.

WHO Library Cataloguing-in-Publication Data

C. Mathers, G. Stevens, Doris Ma Fat, 2009 .

WHO Library Cataloguing-in-Publication Data

C. Mathers, G. Stevens, Doris Ma Fat, 2001 .

Gender and Health Gender in Tuberculosis Research Department of Gender, Women and Health Family and Community Health World Health Organization Gender in Lung Cancer and Smoking Research Who Library Cataloguing-in-publication Data Acknowledgments

Malawi, C. Mathers, R. Sadana, 2022 .

Biochemical and cellular studies of three human 3-phosphoglycerate dehydrogenase variants responsible for pathological reduced L-serine levels.

G. Murtas, L. Pollegioni, B. Campanini, 2023, BioFactors.

Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target

A. Mozzarelli, Marialaura Marchetti, B. Campanini, 2016, Journal of enzyme inhibition and medicinal chemistry.