J. A. Newitt

发表

Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form

Micah T. Nelp, J. Groves, J. Hunt, 2018, Proceedings of the National Academy of Sciences.

Discovery of novel P1 groups for coagulation factor VIIa inhibition using fragment-based screening.

L. Mueller, D. Cheney, W. Metzler, 2015, Journal of medicinal chemistry.

Native mass spectrometry and gas-phase fragmentation provide rapid and in-depth topological characterization of a PROTAC ternary complex.

M. Gross, J. A. Newitt, A. Balog, 2021, Cell chemical biology.

Assessing compound binding to the Eg5 motor domain using a thermal shift assay.

M. Doyle, V. Goldfarb, W. Metzler, 2009, Analytical biochemistry.

The E. coli Signal Recognition Particle Is Required for the Insertion of a Subset of Inner Membrane Proteins

J. A. Newitt, H. Bernstein, N. Ulbrandt, 1997, Cell.

Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors.

A. Doweyko, K. McIntyre, D. Shuster, 2011, Bioorganic & medicinal chemistry letters.

5-amino-pyrazoles as potent and selective p38α inhibitors.

A. Doweyko, R. Moquin, K. McIntyre, 2010, Bioorganic & medicinal chemistry letters.

The Structure of Multiple Polypeptide Domains Determines the Signal Recognition Particle Targeting Requirement ofEscherichia coli Inner Membrane Proteins

J. A. Newitt, H. Bernstein, N. Ulbrandt, 1999, Journal of bacteriology.

The N-domain of the signal recognition particle 54-kDa subunit promotes efficient signal sequence binding.

J. A. Newitt, H. Bernstein, J. Newitt, 1997, European journal of biochemistry.

Development of a Model Protein Interaction Pair as a Benchmarking Tool for the Quantitative Analysis of 2-Site Protein-Protein Interactions.

A. Yamniuk, M. Doyle, E. Eisenstein, 2015, Journal of biomolecular techniques : JBT.

Native Mass Spectrometry and Gas-Phase Fragmentation Provide Rapid and In-Depth Topological Characterization of a PROTAC Ternary Complex

M. Gross, J. A. Newitt, A. Balog, 2021, Cell chemical biology.