B. Lei

发表

Spectroscopic identification of heme axial ligands in HtsA that are involved in heme acquisition by Streptococcus pyogenes.

Yanchao Ran, Mengyao Liu, Hui Zhu, 2010, Biochemistry.

Direct Hemin Transfer from IsdA to IsdC in the Iron-regulated Surface Determinant (Isd) Heme Acquisition System of Staphylococcus aureus*

Mengyao Liu, Hui Zhu, D. Dooley, 2008, Journal of Biological Chemistry.

Pathway for Heme Uptake from Human Methemoglobin by the Iron-regulated Surface Determinants System of Staphylococcus aureus*

J. Olson, Mengyao Liu, Hui Zhu, 2008, Journal of Biological Chemistry.

The surface protein Shr of Streptococcus pyogenes binds heme and transfers it to the streptococcal heme-binding protein Shp

Mengyao Liu, Hui Zhu, B. Lei, 2008, BMC Microbiology.

The Mechanism of Direct Heme Transfer from the Streptococcal Cell Surface Protein Shp to HtsA of the HtsABC Transporter*

J. Olson, Mengyao Liu, Tyler K. Nygaard, 2006, Journal of Biological Chemistry.

Analysis of a Novel Prophage-encoded Group A Streptococcus Extracellular Phospholipase A2*

Michal J. Nagiec, J. Musser, B. Lei, 2004, Journal of Biological Chemistry.

Genome sequence of a serotype M3 strain of group A Streptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence

Meng-Yao Liu, Todd M. Smith, Benfang Lei, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Isoniazid Activation Defects in Recombinant Mycobacterium tuberculosis Catalase-Peroxidase (KatG) Mutants Evident in InhA Inhibitor Production

J. Musser, B. Lei, S. Tu, 2003, Antimicrobial Agents and Chemotherapy.

Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection.

B. Lei, A. Harmsen, Quinton O King, 2009, The Journal of infectious diseases.

Serotype M3 and M28 Group A Streptococci Have Distinct Capacities to Evade Neutrophil and TNF-α Responses and to Invade Soft Tissues

Mengyao Liu, B. Lei, W. Feng, 2015, PloS one.

Transient weak protein-protein complexes transfer heme across the cell wall of Staphylococcus aureus.

R. Clubb, Mengyao Liu, B. Lei, 2011, Journal of the American Chemical Society.

Direct Heme Transfer Reactions in the Group A Streptococcus Heme Acquisition Pathway

Mengyao Liu, Hui Zhu, B. Lei, 2012, PloS one.

Characterization of Streptococcal Platelet-Activating Factor Acetylhydrolase Variants That Are Involved in Innate Immune Evasion

Mengyao Liu, B. Lei, G. Xie, 2013, Infection and Immunity.

Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

J. Hilmer, B. Bothner, M. Teixeira, 2012, PLoS pathogens.

Group A Streptococcus During Subcutaneous Infection of Mice 2

Mengyao Liu, B. Lei, W. Feng, 2014 .

Opsonophagocytosis-Inhibiting Mac Protein of Group A Streptococcus: Identification and Characteristics of Two Genetic Complexes

J. Musser, Mengyao Liu, B. Lei, 2002, Infection and Immunity.

Identification and Characterization of a Novel Heme-Associated Cell Surface Protein Made by Streptococcus pyogenes

J. Musser, B. Lei, F. DeLeo, 2002, Infection and Immunity.

Identification and Immunogenicity of Group AStreptococcus Culture Supernatant Proteins

J. Musser, B. Lei, S. Mackie, 2000, Infection and Immunity.

Proteins Culture Supernatant Streptococcus A Identification and Immunogenicity of Group

B. Lei, S. Mackie, Stacy M. Mackie, 2000 .

Requirement and Synergistic Contribution of Platelet-Activating Factor Acetylhydrolase Sse and Streptolysin S to Inhibition of Neutrophil Recruitment and Systemic Infection by Hypervirulent emm3 Group A Streptococcus in Subcutaneous Infection of Mice

Mengyao Liu, B. Lei, W. Feng, 2017, Infection and Immunity.

A Neutralizing Monoclonal IgG1 Antibody of Platelet-Activating Factor Acetylhydrolase SsE Protects Mice against Lethal Subcutaneous Group A Streptococcus Infection

Mengyao Liu, Hui Zhu, B. Lei, 2015, Infection and Immunity.

A StreptococcusMurine Infection with Group Regulatory System CovRS in Infiltration by the Two-Component Regulation of Inhibition of Neutrophil

Mengyao Liu, B. Lei, W. Feng, 2014 .

Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis

J. Musser, M. Graham, M. Federle, 2001, Nature Medicine.

Active and Passive Immunizations with the Streptococcal Esterase Sse Protect Mice against Subcutaneous Infection with Group A Streptococci

Mengyao Liu, Hui Zhu, B. Lei, 2007, Infection and Immunity.

A Naturally Occurring Single Nucleotide Mutation Significantly Impairs Necrotizing Fasciitis (“Flesh Eating”) Capacity of Group A Streptococcus (GAS)

Adeline R. Whitney, R. Olsen, J. Musser, 2008 .

Genome-wide protective response used by group A Streptococcus to evade destruction by human polymorphonuclear leukocytes

J. Musser, B. Lei, D. Sturdevant, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axis

Adeline R. Whitney, R. Olsen, J. Musser, 2010, Proceedings of the National Academy of Sciences.

The Mga Regulon but Not Deoxyribonuclease Sda1 of Invasive M1T1 Group A Streptococcus Contributes to In Vivo Selection of CovRS Mutations and Resistance to Innate Immune Killing Mechanisms

Mengyao Liu, B. Lei, D. Nelson, 2015, Infection and Immunity.

Benfang Lei's research on heme acquisition in Gram-positive pathogens and bacterial pathogenesis.

B. Lei, 2010, World journal of biological chemistry.

Reply to “Streptococcus pyogenes and phagocytic killing”

J. Musser, B. Lei, F. DeLeo, 2002, Nature Medicine.

Identification of new candidate vaccine antigens made by Streptococcus pyogenes: purification and characterization of 16 putative extracellular lipoproteins.

J. Musser, Mengyao Liu, B. Lei, 2004, The Journal of infectious diseases.

Heme Transfer from Streptococcal Cell Surface Protein Shp to HtsA of Transporter HtsABC

Mengyao Liu, B. Lei, 2005, Infection and Immunity.

ABC transporter FtsABCD of Streptococcus pyogenes mediates uptake of ferric ferrichrome

Mengyao Liu, B. Lei, M. J. McClure, 2005, BMC Microbiology.

Identification and Characterization of HtsA, a Second Heme-Binding Protein Made by Streptococcus pyogenes

J. Musser, Mengyao Liu, B. Lei, 2003, Infection and Immunity.

Differential Regulation of Iron- and Manganese-Specific MtsABC and Heme-Specific HtsABC Transporters by the Metalloregulator MtsR of Group A Streptococcus

Mengyao Liu, B. Lei, Maki Fukumura, 2006, Infection and Immunity.

Tissue Tropism in Streptococcal Infection: Wild-Type M1T1 Group A Streptococcus Is Efficiently Cleared by Neutrophils Using an NADPH Oxidase-Dependent Mechanism in the Lung but Not in the Skin

M. Jutila, Mengyao Liu, B. Lei, 2019, Infection and Immunity.

Skin Infection and Dissemination in Mice

Mengyao Liu, Hui Zhu, B. Lei, 2009 .

The Secreted Esterase of Group A Streptococcus Is Important for Invasive Skin Infection and Dissemination in Mice

Mengyao Liu, Hui Zhu, B. Lei, 2009, Infection and Immunity.

IgG Endopeptidase SeMac does not Inhibit Opsonophagocytosis of Streptococcus equi Subspecies equi by Horse Polymorphonuclear Leukocytes

Mengyao Liu, B. Lei, 2010, The open microbiology journal.

Defects in ex vivo and in vivo growth and sensitivity to osmotic stress of group A Streptococcus caused by interruption of response regulator gene vicR.

Mengyao Liu, B. Lei, M. J. McClure, 2006, Microbiology.

Insight of Host Immune Evasion Mediated by Two Variants of Group A Streptococcus Mac Protein*

J. Musser, P. Sun, B. Lei, 2004, Journal of Biological Chemistry.

Histidine and Aspartic Acid Residues Important for Immunoglobulin G Endopeptidase Activity of the Group A Streptococcus Opsonophagocytosis-Inhibiting Mac Protein

Michal J. Nagiec, J. Musser, Mengyao Liu, 2003, Infection and Immunity.

Non-Heme-Binding Domains and Segments of the Staphylococcus aureus IsdB Protein Critically Contribute to the Kinetics and Equilibrium of Heme Acquisition from Methemoglobin

V. Copié, Mengyao Liu, Hui Zhu, 2014, PloS one.

Axial ligand replacement mechanism in heme transfer from streptococcal heme-binding protein Shp to HtsA of the HtsABC transporter.

G. R. Malmirchegini, R. Clubb, Yanchao Ran, 2013, Biochemistry.

Lipid oxidation in trout muscle is strongly inhibited by a protein that specifically binds hemin released from hemoglobin.

M. Richards, B. Lei, H. Cai, 2013, Journal of agricultural and food chemistry.

Bis-methionine Ligation to Heme Iron in the Streptococcal Cell Surface Protein Shp Facilitates Rapid Hemin Transfer to HtsA of the HtsABC Transporter*

J. Olson, G. Phillips, Yanchao Ran, 2007, Journal of Biological Chemistry.

Identification and characterization of the heme-binding proteins SeShp and SeHtsA of Streptococcus equi subspecies equi

Mengyao Liu, Tyler K. Nygaard, B. Lei, 2006, BMC Microbiology.

Hypervirulent Group A Streptococcus of Genotype emm3 Invades the Vascular System in Pulmonary Infection of Mice

Mengyao Liu, B. Lei, W. Feng, 2018, Infection and Immunity.

Reply to Eisenhut

B. Lei, A. Harmsen, Quinton O. King, 2010 .

Esterase SeE of Streptococcus equi ssp. equi is a novel nonspecific carboxylic ester hydrolase.

Mengyao Liu, Hui Zhu, B. Lei, 2008, FEMS microbiology letters.

A Streptococcus Contributes to in vivo Selection of CovRS Mutations and

Mengyao Liu, B. Lei, D. Nelson, 2015 .

Pathogenesis of Hypervirulent Group A Streptococcus.

Mengyao Liu, B. Lei, 2018, Japan journal of medicine.

Pneumococcal Surface Protein A Contributes to Secondary Streptococcus pneumoniae Infection following Influenza Infection influenza pneumococcal NanA cleaves terminal acid residues on respiratory-surface glycoconjugates promoting adhesion and

B. Lei, A. Harmsen, Quinton O. King, 2009 .

The Two-Component Regulatory System VicRK is Important to Virulence of Streptococcus equi Subspecies equi

Mengyao Liu, Hui Zhu, B. Lei, 2008, The open microbiology journal.

The sagA/pel locus does not regulate the expression of the M protein of the M1T1 lineage of group A Streptococcus

Mengyao Liu, B. Lei, W. Feng, 2013, Virulence.

Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription

J. Musser, B. Lei, N. Green, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A periplasmic arsenite-binding protein involved in regulating arsenite oxidation.

Guanghui Liu, Walid Maaty, B. Bothner, 2012, Environmental microbiology.

Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X‐linked agammaglobulinemia

Benfang Lei, S. Tzeng, P. Roller, 2000, Protein science : a publication of the Protein Society.

Complete Genome Sequence of Hypervirulent Streptococcus pyogenes emm3 Strain 1838

C. Yeoman, Mengyao Liu, B. Lei, 2019, Microbiology Resource Announcements.

Characterization of an Extracellular Virulence FactorMade by Group A Streptococcus with Homology to theListeria monocytogenes Internalin Family ofProteins

J. Musser, Mengyao Liu, B. Lei, 2003, Infection and Immunity.

Toward a genome-scale understanding of group A Streptococcus pathogenesis.

J. Musser, M. Graham, B. Lei, 2001, Current opinion in microbiology.

Host-to-Host Group A Streptococcus Transmission Causes Infection of the Lamina Propria but Not Epithelium of the Upper Respiratory Tract in MyD88-Deficient Mice

B. Lei, M. Quinn, Dylan Minor, 2021, Infection and immunity.

Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice

F. Fang, Mengyao Liu, B. Lei, 2016, PloS one.

Neutrophils Select Hypervirulent CovRS Mutants of M1T1 Group A Streptococcus during Subcutaneous Infection of Mice

Mengyao Liu, B. Lei, W. Feng, 2014, Infection and Immunity.

Staphylococcus aureus Uses a Novel Multidomain Receptor to Break Apart Human Hemoglobin and Steal Its Heme*

D. Gell, G. R. Malmirchegini, R. Clubb, 2012, The Journal of Biological Chemistry.

Neutrophil isolation from nonhuman species.

Adeline R. Whitney, B. Lei, F. DeLeo, 2014, Methods in molecular biology.

Neutrophil isolation from nonhuman species.

Benfang Lei, B. Lei, M. Quinn, 2007, Methods in molecular biology.

Isolation of Neutrophils from Nonhuman Species.

B. Lei, F. DeLeo, Natalia Małachowa, 2020, Methods in molecular biology.

Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus

Rebecca Moore, Brittany A. Fonner, Brian P. Tripet, 2014, Biochemistry.

1H, 13C, 15N backbone and side chain NMR resonance assignments of the N-terminal NEAr iron transporter domain 1 (NEAT 1) of the hemoglobin receptor IsdB of Staphylococcus aureus

Brittany A. Fonner, V. Copié, Hui Zhu, 2014, Biomolecular NMR assignments.

Bis-methionyl coordination in the crystal structure of the heme-binding domain of the streptococcal cell surface protein Shp.

G. Phillips, J. Olson, Mengyao Liu, 2007, Journal of molecular biology.

Prophage Induction and Expression of Prophage-EncodedVirulence Factors in Group A Streptococcus Serotype M3 StrainMGAS315

James M. Musser, Benfang Lei, J. Musser, 2003, Infection and Immunity.

Slipped-strand mispairing within a polycytidine tract in transcriptional regulator mga leads to M protein phase variation and Mga length polymorphism in Group A Streptococcus

Mengyao Liu, B. Lei, Yunjuan Bao, 2023, Frontiers in Microbiology.

Regulation of Inhibition of Neutrophil Infiltration by the Two-Component Regulatory System CovRS in Subcutaneous Murine Infection with Group A Streptococcus

Mengyao Liu, B. Lei, Weicheng Bei, 2013, Infection and Immunity.

Null Mutations of Group A Streptococcus Orphan Kinase RocA: Selection in Mouse Infection and Comparison with CovS Mutations in Alteration of In Vitro and In Vivo Protease SpeB Expression and Virulence

C. Yeoman, Mengyao Liu, B. Lei, 2016, Infection and Immunity.