Barbora Mrázová

Optimalization of preparation of apo-cytochrome b5 utilizing apo-myoglobin

Barbora Mrázová, M. Martínková, Václav Martínek, 2008, Interdisciplinary toxicology.

Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney.

Barbora Mrázová, E. Frei, M. Stiborová, 2010, Neuro endocrinology letters.

The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism

R. Vaclavikova, L. Svobodová, J. Hudeček, 2007, Drug Metabolism and Disposition.

Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy.

J. Hudeček, Barbora Mrázová, Václav Martínek, 2011, Biochemical pharmacology.

Preparation of apo-cytochrome b5 utilizing heme transfer to apo-myoglobin.

Barbora Mrázová, M. Martínková, Václav Martínek, 2009, Neuro endocrinology letters.