S. Ghanem

发表

A Role for CEACAM2 protein in Insulin Secretion, Clearance and Action

S. Ghanem, 2017 .

Reduced Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Level in Obesity

L. Yin, S. Najjar, R. Garofalo, 2017, Front. Endocrinol..

Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis[S]

L. Yin, S. Najjar, X. Tong, 2016, Journal of Lipid Research.

Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance

S. Najjar, S. Ghanem, A. Giacca, 2021, International journal of molecular sciences.

Exenatide induces carcinoembryonic antigen‐related cell adhesion molecule 1 expression to prevent hepatic steatosis

S. Najjar, S. Ghanem, V. Puri, 2017, Hepatology communications.

Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases

D. Erskine, J. Attems, C. Morris, 2020, Brain pathology.

Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene

Jiang Hu, R. Kulkarni, S. Najjar, 2017, Diabetologia.

Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2)*

R. Kulkarni, T. Kitamura, S. Ramakrishnan, 2015, The Journal of Biological Chemistry.

Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity*

S. Ramakrishnan, S. Najjar, S. Ghanem, 2016, The Journal of Biological Chemistry.

CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.

D. Jackson, S. Najjar, S. Ghanem, 2014, Blood.

Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue

W. Philbrick, S. Najjar, S. Ghanem, 2015, Front. Endocrinol..

S. Ghanem, O. El‐Agnaf, Ilham Y Abdi, 2022, Neurobiology of Disease.

STAT5A/5B-specific expansion and transformation of hematopoietic stem cells

R. Moriggl, F. Gouilleux, V. Gouilleux-Gruart, 2017, Blood Cancer Journal.

Novel engineered nanobodies specific for N‐terminal region of alpha‐synuclein recognize Lewy‐body pathology and inhibit in‐vitro seeded aggregation and toxicity

D. Erskine, P. Kolatkar, S. Ghanem, 2022, The FEBS journal.

FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway.

W. Shou, T. Hinds, S. Najjar, 2014, Molecular endocrinology.

PLATELETS AND THROMBOPOIESIS CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo

D. Jackson, S. Najjar, S. Ghanem, 2014 .

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

D. Erskine, J. Attems, R. Guerreiro, 2022, Brain : a journal of neurology.

Prion-like α-synuclein pathology in the brains of infants: Krabbe disease as a novel seed-competent α-synucleinopathy

D. Erskine, J. Attems, R. Guerreiro, 2021, bioRxiv.

Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage

D. Erskine, S. Ghanem, W. V. D. van de Berg, 2022, Neurology.

RYR2, PTDSS1 and AREG genes are implicated in a Lebanese population-based study of copy number variation in autism

F. Kobeissy, S. Ghanem, Joelle Makoukji, 2016, Scientific Reports.

Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver Disease

L. Yin, S. Najjar, R. Garofalo, 2017, Front. Endocrinol..

Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.

S. Najjar, S. Ghanem, Jason K. Kim, 2019, Metabolism: clinical and experimental.

Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers

S. Ghanem, N. Vaikath, O. El‐Agnaf, 2022, International journal of molecular sciences.

Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity

S. Ghanem, N. Vaikath, O. El‐Agnaf, 2021, Molecules.

α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

I. McKeith, D. Erskine, J. Attems, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice

S. Najjar, S. Ghanem, G. Dogbey, 2017, Diabetologia.

Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein Fibrils.

S. Ghanem, N. Vaikath, O. El‐Agnaf, 2022, ACS chemical neuroscience.

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts

D. Eliezer, S. Ghanem, N. Vaikath, 2020, BMC Complementary Medicine and Therapies.

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity

D. Erskine, S. Ghanem, N. Vaikath, 2020, Scientific Reports.

Leptin Resistance Contributes to Obesity in Mice with Null Mutation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1*

S. Ergün, S. Najjar, S. Ghanem, 2016, The Journal of Biological Chemistry.

Screening for Novel Inhibitors of Amyloid Beta Aggregation and Toxicity as Potential Drugs for Alzheimer’s Disease

S. Ghanem, N. Vaikath, K. Vekrellis, 2023, International journal of molecular sciences.

Rapid Assessment of CRISPR Transfection Efficiency and Enrichment of CRISPR Induced Mutations Using a Dual-Fluorescent Stable Reporter System

S. Ghanem, O. El‐Agnaf, Mustapha Aouida, 2022, Frontiers in Genome Editing.