M. Rudling

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Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice

Eva-Marie Andersson, T. Lundåsen, M. Snaith, 2012, PLoS ONE.

Contrasting Effects of Growth Hormone and Insulin-Like Growth Factor I on the Biological Activities of Endotoxin in the Rat1.

B. Angelin, M. Rudling, W. Liao, 1997, Endocrinology.

Activation of VPAC1 receptors aggravates early atherosclerosis in hypercholesterolemic apolipoprotein E-deficient mice.

M. Rudling, G. Hansson, P. Olofsson, 2010, Biochemical and biophysical research communications.

Disruption of TGF-β signaling in T cells accelerates atherosclerosis

R. Flavell, L. Gorelik, M. Rudling, 2003 .

Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.

J. Baxter, P. Webb, T. Scanlan, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Effects of Cholesteryl Ester Transfer Protein Inhibition on High-Density Lipoprotein Subspecies, Apolipoprotein A-I Metabolism, and Fecal Sterol Excretion

D. Rader, E. Schaefer, B. Angelin, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.

L. Boon, L. Beckers, M. Daemen, 2013, European heart journal.

Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation – a double‐blind study

M. Rudling, M. Simrén, P. Gillberg, 2011, Alimentary pharmacology & therapeutics.

Effects of combined treatment with pravastatin and ursodeoxycholic acid on hepatic cholesterol metabolism

S. Sahlin, B. Nyberg, M. Rudling, 2002, European journal of clinical investigation.

The Liver-Selective Thyromimetic T-0681 Influences Reverse Cholesterol Transport and Atherosclerosis Development in Mice

M. Rudling, C. Fiévet, J. Patsch, 2010, PloS one.

Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone.

B. Angelin, M. Rudling, Y. Bonde, 2008, Gastroenterology.

Reduced plasma high-density lipoprotein cholesterol in hyperthyroid mice coincides with decreased hepatic adenosine 5'-triphosphate-binding cassette transporter 1 expression.

M. Rudling, C. Fiévet, J. Patsch, 2008, Endocrinology.

Critical role of cholic acid for development of hypercholesterolemia and gallstones in diabetic mice.

M. Rudling, I. Björkhem, C. Einarsson, 2006, Biochemical and biophysical research communications.

Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy.

G. Gahrton, G. Juliusson, B. Angelin, 1990, Proceedings of the National Academy of Sciences of the United States of America.

AUTOIMMUNE, CHOLESTATIC AND BILIARY DISEASE Stimulation of Murine Biliary Cholesterol Secretion by Thyroid Hormone is Dependent on a Functional ABCG5/G8 Complex

B. Angelin, M. Rudling, F. Kuipers, 2012 .

Bile acid sequestrants: mechanisms of action on bile acid and cholesterol metabolism

K. Einarsson, B. Angelin, M. Rudling, 2011, European Journal of Clinical Pharmacology.

Influence of pravastatin, a specific inhibitor of HMG-CoA reductase, on hepatic metabolism of cholesterol.

K. Einarsson, B. Angelin, M. Rudling, 1990, The New England journal of medicine.

Delivery of aclacinomycin A to human glioma cells in vitro by the low-density lipoprotein pathway.

V. P. Collins, M. Rudling, C. Peterson, 1983, Cancer research.

A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings

G. Helmlinger, B. Angelin, M. Rudling, 2020, Cellular and Molecular Gastroenterology and Hepatology.

Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS

M. Rudling, H. Törnblom, M. Simrén, 2014, Gut.

Circulating fibroblast growth factors as metabolic regulators--a critical appraisal.

B. Angelin, M. Rudling, T. Larsson, 2012, Cell metabolism.

Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorption

L. Öhman, M. Rudling, P. Stotzer, 2006, European journal of gastroenterology & hepatology.

Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man

T. Lundåsen, B. Angelin, M. Rudling, 2006, Journal of internal medicine.

Role of Dietary Fats in Modulating Cardiometabolic Risk During Moderate Weight Gain: A Randomized Double‐Blind Overfeeding Trial (LIPOGAIN Study)

J. Ärnlöv, A. Larsson, M. Rudling, 2014, Journal of the American Heart Association.

Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders

Hetal N. Patel, E. Levy, S. Islam, 2003, Nature Genetics.

Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol.

B. Angelin, M. Rudling, P. Parini, 2007, American journal of physiology. Endocrinology and metabolism.

Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats.

B. Angelin, M. Rudling, P. Parini, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis.

B. Angelin, M. Rudling, C. Gälman, 2005, Gastroenterology.

Circulating Proprotein Convertase Subtilisin Kexin Type 9 Has a Diurnal Rhythm Synchronous With Cholesterol Synthesis and Is Reduced by Fasting in Humans

M. Eriksson, I. Hafström, B. Angelin, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study.

I. Dahlman, M. Rudling, U. Risérus, 2015, The American journal of clinical nutrition.

Interleukin-10 Deficiency Increases Atherosclerosis, Thrombosis, and Low-density Lipoproteins in Apolipoprotein E Knockout Mice

J. Michel, M. Rudling, G. Hansson, 2003, Molecular medicine.

Endogenous Estrogens Lower Plasma PCSK9 and LDL Cholesterol But Not Lp(a) or Bile Acid Synthesis in Women

B. Angelin, M. Rudling, O. Hovatta, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice.

S. Akira, H. Ljunggren, K. Takeda, 2003, Cardiovascular research.

Impaired Cholesterol Efflux Capacity of High-Density Lipoprotein Isolated From Interstitial Fluid in Type 2 Diabetes Mellitus—Brief Report

B. Angelin, M. Rudling, P. Parini, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Endotoxin suppresses mouse hepatic low‐density lipoprotein–receptor expression via a pathway independent of the toll‐like receptor 4

B. Angelin, M. Rudling, W. Liao, 1999, Hepatology.

Cholesterol Synthesis Inhibition Elicits an Integrated Molecular Response in Human Livers Including Decreased ACAT2

S. Ōmura, M. Eriksson, S. Sahlin, 2008, Arteriosclerosis, thrombosis, and vascular biology.

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.

M. Eriksson, I. Hafström, B. Angelin, 2008, Cell metabolism.

Hepatic cholesterol metabolism in human obesity

K. Einarsson, B. Angelin, M. Rudling, 1997, Hepatology.

Regulation of hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and cholesterol 7alpha-hydroxylase mRNAs in human liver.

S. Sahlin, B. Angelin, M. Rudling, 2002, The Journal of clinical endocrinology and metabolism.

Interstitial fluid lipoproteins

B. Angelin, M. Rudling, J. Lundberg, 2013, Current opinion in lipidology.

CD1d-dependent Activation of NKT Cells Aggravates Atherosclerosis

H. Ljunggren, M. Rudling, G. Hansson, 2004, The Journal of Experimental Medicine.

Leptin Induces the Hepatic High Density Lipoprotein Receptor Scavenger Receptor B Type I (SR-BI) but Not Cholesterol 7α-Hydroxylase (Cyp7a1) in Leptin-deficient (ob/ob) Mice*

T. Lundåsen, B. Angelin, M. Rudling, 2003, Journal of Biological Chemistry.

Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice.

J. Gustafsson, C. Ohlsson, M. Bohlooly-y, 2000, Biochemical and biophysical research communications.

Obesity and Disturbed Lipoprotein Profile in Estrogen Receptor-α-Deficient Male Mice

J. Gustafsson, C. Ohlsson, B. Angelin, 2000 .

Influence of bezafibrate on hepatic cholesterol metabolism in gallstone patients: Reduced activity of cholesterol 7α‐hydroxylase

K. Einarsson, B. Angelin, M. Rudling, 1995, Hepatology.

Lesion Development and Response to Immunization Reveal a Complex Role for CD4 in Atherosclerosis

M. Rudling, G. Hansson, P. Parini, 2005, Circulation research.

PPARα is a key regulator of hepatic FGF21

T. Lundåsen, B. Angelin, M. Rudling, 2007 .

PPARalpha is a key regulator of hepatic FGF21.

T. Lundåsen, B. Angelin, M. Rudling, 2007, Biochemical and biophysical research communications.

Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors.

B. Angelin, M. Rudling, L. Persson, 2009, Endocrinology.

Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial

J. Borén, M. Orho-Melander, A. Larsson, 2019, The Journal of clinical endocrinology and metabolism.

Effects of food or sleep deprivation during civilian survival training on clinical chemistry variables.

M. Rudling, E. Granström, L. Ståhle, 2013, Wilderness & environmental medicine.

Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma.

M. Eriksson, B. Angelin, M. Rudling, 1989, The Journal of clinical investigation.

Effects of stigmastanyl-phosphocholine (Ro 16-6532) and lovastatin on lipid and lipoprotein levels and lipoprotein metabolism in the hamster on different diets.

M. Rudling, H. Kempen, J. Himber, 1995, Journal of lipid research.

Oestrogen‐induced changes in lipoprotein metabolism: role in prevention of atherosclerosis in the cholesterol‐fed rabbit

M. Eriksson, B. Angelin, M. Rudling, 1989, European journal of clinical investigation.

Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol.

B. Angelin, M. Rudling, C. Gälman, 2002, Endocrinology.

Prolonged Stimulation of the Adrenals by Corticotropin Suppresses Hepatic Low-Density Lipoprotein and High-Density Lipoprotein Receptors and Increases Plasma Cholesterol.

B. Angelin, M. Rudling, Cecilia Ga Lman, 2002, Endocrinology.

1 PPAR α is a key regulator of hepatic FGF 21

T. Lundåsen, B. Angelin, M. Rudling, 2019 .

Monitoring hepatic cholesterol 7α-hydroxylase activity by assay of the stable bile acid intermediate 7α-hydroxy-4-cholesten-3-one in peripheral blood Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.D200043-JLR200

B. Angelin, M. Rudling, C. Gälman, 2003, Journal of Lipid Research.

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

M. Rudling, G. Eggertsen, Y. Bonde, 2014, Journal of internal medicine.

Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease

J. Miquel, F. Nervi, M. Rudling, 2007, Hepatology.

Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood.

B. Angelin, M. Rudling, C. Gälman, 2003, Journal of lipid research.

Cholestyramine treatment of healthy humans rapidly induces transient hypertriglyceridemia when treatment is initiated.

B. Angelin, M. Rudling, S. Straniero, 2017, American journal of physiology. Endocrinology and metabolism.

Specific inhibition of bile acid transport alters plasma lipids and GLP-1

J. Holst, M. Camilleri, M. Rudling, 2015, BMC Cardiovascular Disorders.

Coordinate Regulation of Cholesterol 7α-Hydroxylase and HMG-CoA Reductase in the Liver

M. Rudling, I. Björkhem, E. Lund, 1997 .

Pharmacological interference with intestinal bile acid transport reduces plasma cholesterol in LDL receptor/apoE deficiency

Ann-Margret Östlund-Lindqvist, B. Angelin, M. Rudling, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Regulation of hepatic cholesterol metabolism in humans: stimulatory effects of cholestyramine on HMG-CoA reductase activity and low density lipoprotein receptor expression in gallstone patients.

K. Einarsson, B. Angelin, M. Rudling, 1990, Journal of lipid research.

LDL receptors in bovine tissues assayed as the heparin-sensitive binding of 125I-labeled LDL in homogenates: relation between liver LDL receptors and serum cholesterol in the fetus and post term.

M. Rudling, C. Peterson, 1985, Biochimica et biophysica acta.

A simple binding assay for the determination of low-density lipoprotein receptors in cell homogenates.

M. Rudling, C. Peterson, 1985, Biochimica et biophysica acta.

Biphasic effects of the natural estrogen 17beta-estradiol on hepatic cholesterol metabolism in intact female rats.

B. Angelin, M. Rudling, A. Stavreus-Evers, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Importance of estrogen receptors in hepatic LDL receptor regulation.

B. Angelin, M. Rudling, P. Parini, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Lipoprotein Metabolism in the Fat Zucker Rat: Reduced Basal Expression but Normal Regulation of Hepatic Low Density Lipoprotein Receptors* Materials and Methods Material Animals and Experimental Procedure

B. Angelin, M. Rudling, W. Liao, 2022 .

Hepatic cholesterol metabolism in estrogen-treated men.

M. Eriksson, K. Einarsson, B. Angelin, 1992, Gastroenterology.

Role of the liver for the receptor-mediated catabolism of low-density lipoprotein in the 17 alpha-ethinylestradiol-treated rat.

M. Rudling, 1987, Biochimica et biophysica acta.

Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel‐filtration system

B. Angelin, M. Rudling, P. Parini, 2006, European journal of clinical investigation.

Effects of growth hormone on hepatic cholesterol metabolism. Lessons from studies in rats and humans.

B. Angelin, M. Rudling, P. Parini, 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat.

B. Angelin, M. Rudling, P. Parini, 1997, The Journal of clinical investigation.

Growth Hormone and Bile Acid Synthesis Key Role for the Activity of Hepatic Microsomal Cholesterol 7 (cid:97) -hydroxylase in the Rat

B. Angelin, M. Rudling, P. Parini, 1997 .

Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells.

B. Angelin, M. Rudling, G. Norstedt, 1995, Endocrinology.

Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism[S]

B. Angelin, M. Rudling, J. Härdfeldt, 2020, Journal of Lipid Research.

Understanding mouse bile acid formation: Is it time to unwind why mice and rats make unique bile acids?1

M. Rudling, 2016, Journal of Lipid Research.

Mice Abundant in Muricholic Bile Acids Show Resistance to Dietary Induced Steatosis, Weight Gain, and to Impaired Glucose Metabolism

M. Rudling, G. Eggertsen, Y. Bonde, 2016, PloS one.

Stimulation of Apical Sodium-Dependent Bile Acid Transporter Expands the Bile Acid Pool and Generates Bile Acids with Positive Feedback Properties

M. Rudling, Y. Bonde, 2015, Digestive Diseases.

HYPOCHOLESTEROLAEMIA AND INCREASED ELIMINATION OF LOW-DENSITY LIPOPROTEINS IN METASTATIC CANCER OF THE PROSTATE

B. Angelin, M. Rudling, P. Henriksson, 1989, The Lancet.

Lipid lowering with thyroid hormone and thyromimetics

B. Angelin, M. Rudling, 2010, Current opinion in lipidology.

Reduced Plasma HDL Cholesterol in Hyperthyroid Mice Coincides with Decreased Hepatic ABCA1 Expression

M. Rudling, C. Fiévet, J. Patsch, 2012 .

Growth hormone potentiates the in vivo biological activities of endotoxin in the rat

B. Angelin, M. Rudling, W. Liao, 1996, European journal of clinical investigation.

Bile acid synthesis is increased in Chilean Hispanics with gallstones and in gallstone high-risk Mapuche Indians.

J. Miquel, F. Nervi, M. Rudling, 2004, Gastroenterology.

Growth hormone reduces plasma cholesterol in LDL receptor‐deficient mice

B. Angelin, M. Rudling, Mats Rudling, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment.

B. Angelin, M. Rudling, P. Parini, 2005, Biochimica et biophysica acta.

Differences in the Regulation of the Classical and the Alternative Pathway for Bile Acid Synthesis in Human Liver

B. Angelin, M. Rudling, I. Björkhem, 2002, The Journal of Biological Chemistry.

Deoxycholic acid treatment in patients with cholesterol gallstones: failure to detect a suppression of cholesterol 7α‐hydroxylase activity

B. Nyberg, B. Angelin, M. Rudling, 1999, Journal of internal medicine.

Bile acid synthesis in primary cultures of rat and human hepatocytes

M. Rudling, A. Mode, I. Björkhem, 1998, Hepatology.

Bile acids and lipoprotein metabolism: a renaissance for bile acids in the post-statin era?

M. Eriksson, B. Angelin, M. Rudling, 1999, Current opinion in lipidology.

Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.

B. Angelin, M. Rudling, Johanna Apro, 2015, Biochemical and biophysical research communications.

Bile acid sequestrants: Mechanisms of action on bile acid and cholesterol metabolism

K. Einarsson, B. Angelin, M. Rudling, 2005, European Journal of Clinical Pharmacology.

Requirement for Thyroid Hormone Receptor (cid:1) in T 3 Regulation of Cholesterol Metabolism in Mice

D. Forrest, B. Angelin, M. Rudling, 2002 .

Hepatic metabolism of cholesterol in Crohn's disease. Effect of partial resection of ileum.

K. Einarsson, B. Angelin, M. Rudling, 1991, Gastroenterology.

The genetic background of gallstone formation: an update.

M. Rudling, H. Marschall, C. Einarsson, 2010, Biochemical and Biophysical Research Communications - BBRC.

Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement.

V. P. Collins, B. Angelin, M. Rudling, 1990, Cancer research.

Lipoproteins and microemulsions as carriers of therapeutic and chemical agents.

M. Rudling, S. Vitols, M. Masquelier, 1991 .

Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol

B. Angelin, M. Rudling, M. Ghosh, 2015, Journal of Lipid Research.

Presence of cholesterol 7 alpha-hydroxylase enzyme protein in COS-cells leads to increased HMG CoA reductase activity.

M. Rudling, I. Björkhem, G. Eggertsen, 1994, Biochemical and biophysical research communications.

The thyromimetic T-0681 protects from atherosclerosis.

B. Foeger, M. Rudling, C. Fiévet, 2009, Journal of lipid research.

Osteoprotegerin Promotes Fibrous Cap Formation in Atherosclerotic Lesions of ApoE-Deficient Mice—Brief Report

A. Nordström, P. Nordström, S. Bergström, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Endogenous histamine reduces plasma insulin-like growth factor I via H1 receptor-mediated pathway in the rat.

B. Angelin, M. Rudling, W. Liao, 1999, European journal of pharmacology.

Hepatic cholesterol metabolism in experimental nephrotic syndrome

E. Humble, M. Rudling, L. Berglund, 1998, Lipids.

CD137 Is Expressed in Human Atherosclerosis and Promotes Development of Plaque Inflammation in Hypercholesterolemic Mice

Lieping Chen, U. Hedin, M. Rudling, 2008, Circulation.

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans[S]

B. Angelin, M. Rudling, D. Lütjohann, 2014, Journal of Lipid Research.

Regulation of bile acid metabolism in biliary atresia: reduction of FGF19 by Kasai portoenterostomy and possible relation to early outcome

B. Angelin, M. Rudling, Ewa C. S. Ellis, 2020, Journal of internal medicine.

Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19

B. Angelin, M. Rudling, C. Gälman, 2011, Journal of internal medicine.

Pronouncedvariationinbileacidsynthesisinhumansis relatedtogender,hypertriglyceridaemiaandcirculating levelsoffibroblastgrowthfactor19

B. Angelin, M. Rudling, C. Gälman, 2011 .

Importance of growth hormone for the induction of hepatic low density lipoprotein receptors.

J. Gustafsson, B. Angelin, M. Rudling, 1992, Proceedings of the National Academy of Sciences of the United States of America.

An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers.

B. Angelin, M. Rudling, A. Al-Khaifi, 2018, Gastroenterology.

Loss of resistance to dietary cholesterol in the rat after hypophysectomy: importance of the presence of growth hormone for hepatic low density lipoprotein-receptor expression.

B. Angelin, M. Rudling, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Effect of 3-thiadicarboxylic acid on lipid metabolism in experimental nephrosis.

M. Rudling, R. Berge, L. Berglund, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

Atheroprotective effect of adjuvants in apolipoprotein E knockout mice.

S. Kaveri, M. Rudling, A. Tchapla, 2006, Atherosclerosis.

Erratum to “Obesity and disturbed lipoprotein profile in estrogen receptor-α-deficient male mice” [Biochem. Biophys. Res. Commun. 278 (2000) 640–645]

J. Gustafsson, C. Ohlsson, M. Bohlooly-y, 2006 .

Sphingosine-1-Phosphate Analogue FTY720 Causes Lymphocyte Redistribution and Hypercholesterolemia in ApoE-Deficient Mice

H. Katus, R. Klingenberg, J. Nofer, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Sphingosine-1-Phosphate Analogue FTY 720 Causes Lymphocyte Redistribution and Hypercholesterolemia in ApoE-Deficient Mice

H. Katus, R. Klingenberg, J. Nofer, 2007 .

Effects of fermented, ropy, non-dairy, oat-based products on serum lipids and the faecal excretion of cholesterol and short chain fatty acids in germfree and conventional rats

M. Rudling, R. Öste, T. Midtvedt, 2002 .

Gallbladder bile supersaturated with cholesterol in gallstone patients preferentially develops from shortage of bile acids

M. Rudling, S. Straniero, Amit Laskar, 2019, Journal of Lipid Research.

Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial ﬂ uid from type 2 diabetes patients patient-oriented and epidemiological research

B. Angelin, M. Rudling, P. Parini, 2015 .

In vitro studies of lipid metabolism in human liver.

K. Einarsson, B. Angelin, M. Rudling, 1987, American heart journal.

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.

T. Lüscher, M. Jauhiainen, R. Klingenberg, 2013, The Journal of clinical investigation.

Pituitary control of lipoprotein and bile acid metabolism in male rats: growth hormone effects are not mediated by prolactin.

B. Angelin, M. Rudling, M. Matasconi, 2004, American journal of physiology. Endocrinology and metabolism.

Studies on lipoprotein metabolism in a family with jejunal chylomicron retention

B. Angelin, M. Rudling, B. Veress, 1995, European journal of clinical investigation.

Content of low density lipoprotein receptors in breast cancer tissue related to survival of patients.

L. Skoog, M. Rudling, C. Peterson, 1986, British medical journal.

Transport and Storage of Anthracyclines in Experimental Systems and Human Leukemia

G. Gahrton, M. Rudling, S. Vitols, 1982 .

CD1d-dependent activation of NKT cells aggravates atherosclerosis.

H. Ljunggren, M. Rudling, G. Hansson, 2004, The Journal of experimental medicine.

Biliary sphincterotomy does not relate to diarrhoea or major changes in bile acid synthesis or plasma lipids

M. Rudling, K. Ung, A. Bajor, 2009, Scandinavian journal of gastroenterology.

Interleukin-6-deficient mice develop mature-onset obesity

C. Ohlsson, J. Jansson, M. Rudling, 2002, Nature Medicine.

The Arachidonic Acid Metabolome Serves as a Conserved Regulator of Cholesterol Metabolism

A. Moschen, W. März, M. Kleber, 2014, Cell metabolism.

Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.

D. Forrest, B. Angelin, M. Rudling, 2000, Molecular endocrinology.

Stimulation of rat hepatic low density lipoprotein receptors by glucagon. Evidence of a novel regulatory mechanism in vivo.

B. Angelin, M. Rudling, J. Clin, 1993, The Journal of clinical investigation.

Growth Hormone Induces Low-Density Lipoprotein Clearance but not Bile Acid Synthesis in Humans

Mats Eriksson, Lars Berglund, M. Eriksson, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.

J. Gustafsson, S. Alberti, B. Angelin, 2001, The Journal of clinical investigation.

Ablation of the very‐long‐chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet‐induced obesity

J. Borén, H. Guillou, M. Rudling, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis

R. Klingenberg, M. Rudling, G. Hansson, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Disruption of TGF-beta signaling in T cells accelerates atherosclerosis.

R. Flavell, L. Gorelik, M. Rudling, 2003, The Journal of clinical investigation.

Budesonide treatment is associated with increased bile acid absorption in collagenous colitis

M. Rudling, K. Ung, A. Kilander, 2006, Alimentary pharmacology & therapeutics.

Growth hormone-mediated alteration of fuel metabolism in the aged rat as determined from transcript profiles.

N. Lee, Ingrid Lönnstedt, M. Rudling, 2004, Physiological genomics.

Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo.

M. Rudling, 1992, Journal of lipid research.

Novel effects of histamine on lipoprotein metabolism: suppression of hepatic low density lipoprotein receptor expression and reduction of plasma high density lipoprotein cholesterol in the rat.

B. Angelin, M. Rudling, W. Liao, 1997, Endocrinology.

R educed atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

S. Akira, H. Ljunggren, K. Takeda, 2003 .

Inhibition of five lipoxygenase activating protein (FLAP) by MK‐886 decreases atherosclerosis in apoE/LDLR‐double knockout mice

M. Rudling, R. Olszanecki, R. Korbut, 2006, European journal of clinical investigation.

Effects of growth hormone on low-density lipoprotein metabolism.

B. Angelin, M. Rudling, H. Olivecrona, 1992, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Regulation of rat hepatic low density lipoprotein receptors. In vivo stimulation by growth hormone is not mediated by insulin-like growth factor I.

B. Angelin, M. Rudling, H. Olivecrona, 1996, The Journal of clinical investigation.

Growth hormone and hepatic lipoprotein metabolism.

B. Angelin, M. Rudling, 1994, Current opinion in lipidology.

Growth Hormone and Bile Acid Synthesis Key Role for the Activity of Hepatic Microsomal Cholesterol 7 a-hydroxylase in the Rat

B. Angelin, M. Rudling, P. Parini, 2013 .

Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity

J. Kullberg, H. Ahlström, M. Rudling, 2017, Journal of internal medicine.

Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial.

M. Uusitupa, J. Kullberg, H. Ahlström, 2012, The American journal of clinical nutrition.

Circulating human hepcidin-25 concentrations display a diurnal rhythm, increase with prolonged fasting, and are reduced by growth hormone administration.

B. Angelin, M. Rudling, L. Ståhle, 2012, Clinical chemistry.

Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements

J. Kullberg, H. Ahlström, M. Rudling, 2019, Nutrition & Diabetes.

Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans

B. Angelin, M. Rudling, M. Lehtihet, 2016, PloS one.

Endotoxin suppresses rat hepatic low-density lipoprotein receptor expression

B. Angelin, M. Rudling, W. Liao, 1996 .

Cryopreserve LDL in the presence of sucrose to protect the biologic properties.

M. Rudling, S. Vitols, M. Masquelier, 1996, Journal of lipid research.

Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.

D. Forrest, B. Angelin, M. Rudling, 2002, Molecular endocrinology.

Autosomal recessive hypercholesterolaemia: normalization of plasma LDL cholesterol by ezetimibe in combination with statin treatment

M. Eriksson, B. Angelin, M. Rudling, 2004, Journal of internal medicine.

Effects of n 2 6 PUFAs compared with SFAs on liver fat , lipoproteins , and inflammation in abdominal obesity : a randomized controlled trial 1 – 4

M. Uusitupa, J. Kullberg, H. Ahlström, 2012 .

Lipoprotein receptors in acute myelogenous leukemia: failure to detect increased low-density lipoprotein (LDL) receptor numbers in cell membranes despite increased cellular LDL degradation.

G. Gahrton, B. Angelin, M. Rudling, 1998, The American journal of pathology.

Long-term GH treatment of GH-deficient adults: Comparison between one and two daily injections

M. Rudling, C. Höybye, 2006, Journal of endocrinological investigation.

The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans

A. Berkenstam, J. Baxter, K. Mellström, 2008, Proceedings of the National Academy of Sciences.

Low density lipoprotein receptor-binding activity in human tissues: quantitative importance of hepatic receptors and evidence for regulation of their expression in vivo.

K. Einarsson, B. Angelin, M. Rudling, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Thyromimetics: a journey from bench to bed-side.

M. Rudling, P. Eller, I. Tancevski, 2011, Pharmacology & therapeutics.

The Bile Acid Turnover Rate Assessed with the 75SeHCAT Test Is Stable in Chronic Diarrhoea but Slightly Decreased in Healthy Subjects After a Long Period of Time

M. Rudling, K. Ung, A. Kilander, 2008, Digestive Diseases and Sciences.

Asynchronous rhythms of circulating conjugated and unconjugated bile acids in the modulation of human metabolism

B. Angelin, M. Rudling, S. Straniero, 2018, Journal of internal medicine.

Observations suggesting bioactive Fgf15 is not present in mouse blood

M. Rudling, 2013, Gut.

Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C‐III

M. Eriksson, B. Angelin, M. Rudling, 2017, Journal of internal medicine.

Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial fluid from type 2 diabetes patients[S]

B. Angelin, M. Rudling, P. Parini, 2015, Journal of Lipid Research.

Increased synthesis of bile acids in gallstone disease is a global finding and not a “peculiar condition” solely in Chile

M. Rudling, 2008, Hepatology.

Coordinate regulation of cholesterol 7 alpha-hydroxylase and HMG-CoA reductase in the liver.

M. Rudling, I. Björkhem, E. Lund, 1997, Sub-cellular biochemistry.

Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels are coordinately reduced in human renal cell carcinoma.

M. Rudling, V. Collins, Mats Rudling, 1996, Biochimica et biophysica acta.

Insulin-like growth factor I for growth hormone therapy

B. Angelin, M. Rudling, W. Liao, 2000, The Lancet.

Authors’ response: Bile acids are important in the pathophysiology of IBS

M. Rudling, H. Törnblom, M. Simrén, 2014, Gut.

Endotoxin suppresses rat hepatic low-density lipoprotein receptor expression.

B. Angelin, M. Rudling, W. Liao, 1995, The Biochemical journal.

Influence of bezafibrate on hepatic cholesterol metabolism in gallstone patients: Reduced activity of cholesterol 7α‐hydroxylase

K. Einarsson, B. Angelin, M. Rudling, 1995, Hepatology.

Growth hormone and low-density lipoproteins.

B. Angelin, M. Rudling, H. Olivecrona, 1993, Acta Endocrinologica.

Circulating fibroblast growth factors as metabolic regulators--a critical appraisal.

B. Angelin, M. Rudling, T. Larsson, 2012, Cell metabolism.

Hypocholesterolemia in cancer patients may be caused by elevated LDL receptor activities in malignant cells

H. Blomgren, L. Skoog, M. Rudling, 1985, Medical oncology and tumor pharmacotherapy.

Effects of Cholesteryl Ester Transfer Protein Inhibition on High-Density Lipoprotein Subspecies, Apolipoprotein A-I Metabolism, and Fecal Sterol Excretion

D. Rader, E. Schaefer, B. Angelin, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Contrasting effects of growth hormone and insulin-like growth factor I on the biological activities of endotoxin in the rat.

B. Angelin, M. Rudling, W. Liao, 1997, Endocrinology.

Cholesterol Synthesis Inhibition Elicits an Integrated Molecular Response in Human Livers Including Decreased ACAT2

S. Ōmura, M. Eriksson, S. Sahlin, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Lipid lowering with thyroid hormone and thyromimetics

B. Angelin, M. Rudling, 2010, Current opinion in lipidology.

Thyromimetics: a journey from bench to bed-side.

M. Rudling, P. Eller, I. Tancevski, 2011, Pharmacology & therapeutics.

Brief Definitive Report Cd1d-dependent Activation of Nkt Cells Aggravates Atherosclerosis

H. Ljunggren, M. Rudling, G. Hansson, 2022 .

CD1d-dependent Activation of NKT Cells Aggravates Atherosclerosis

H. Ljunggren, M. Rudling, G. Hansson, 2004, The Journal of experimental medicine.

Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol.

B. Angelin, M. Rudling, Cecilia Gälman, 2002, Endocrinology.