G. Fenzi

发表

Insulin stimulates fibroblast proliferation through calcium-calmodulin-dependent kinase II

M. Illario, M. Vitale, S. Monaco, 2009, Cell cycle.

Neuropsychological assessment in schoolchildren from an area of moderate iodine deficiency

C. Marcocci, A. Pinchera, F. Santini, 1990, Journal of endocrinological investigation.

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes

P. Larsen, C. Missero, A. Bianco, 2007, Proceedings of the National Academy of Sciences.

Detection of RET/PTC, TRK and BRAF mutations in preoperative diagnosis of thyroid nodules with indeterminate cytological findings

G. Troncone, V. Marotta, M. Sapio, 2007, Clinical endocrinology.

Integrin-dependent cell growth and survival are mediated by different signals in thyroid cells.

M. Illario, C. Miele, M. Andreucci, 2003, The Journal of clinical endocrinology and metabolism.

Calcium/Calmodulin-dependent Protein Kinase II Binds to Raf-1 and Modulates Integrin-stimulated ERK Activation*

M. Illario, M. Vitale, G. Fenzi, 2003, Journal of Biological Chemistry.

Analysis of cancer/testis antigens in sporadic medullary thyroid carcinoma: expression and humoral response to NY-ESO-1.

A. Pinchera, M. Maio, M. Vitale, 2003, The Journal of clinical endocrinology and metabolism.

Transcription Factor Nkx-2.5 Induces Sodium/Iodide Symporter Gene Expression and Participates in Retinoic Acid- and Lactation-Induced Transcription in Mammary Cells

M. Vitale, G. Fenzi, G. Rossi, 2004, Molecular and Cellular Biology.

β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells.

P. Larsen, G. Troncone, G. Fenzi, 2012, Gastroenterology.

Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.

V. Stoppioni, P. Macchia, L. Chiovato, 2006, The Journal of clinical endocrinology and metabolism.

The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration.

R. DePinho, P. Larsen, J. Paik, 2010, The Journal of clinical investigation.

Iodide Excess Induces Apoptosis in Thyroid Cells through a p53-Independent Mechanism Involving Oxidative Stress1.

F. Bogazzi, E. Martino, M. Vitale, 2000, Endocrinology.

Transcription Factor Nkx-2.5 Induces Sodium/Iodide Symporter Gene Expression and Participates in Retinoic Acid- and Lactation-Induced Transcription in Mammary Cells

M. Vitale, G. Fenzi, G. Rossi, 2004, Molecular and Cellular Biology.

Activation of the ret oncogene in human thyroid carcinomas

M. Santoro, A. Fusco, G. Salvatore, 1993 .

The primary occurrence of BRAF(V600E) is a rare clonal event in papillary thyroid carcinoma.

V. Marotta, M. Sapio, Anna Guerra, 2012, The Journal of clinical endocrinology and metabolism.

High growth rate of benign thyroid nodules bearing RET/PTC rearrangements.

V. Marotta, M. Sapio, Anna Guerra, 2011, The Journal of clinical endocrinology and metabolism.

Prevalence of RET/PTC rearrangement in benign and malignant thyroid nodules and its clinical application.

V. Marotta, M. Sapio, Anna Guerra, 2011, Endocrine journal.

Mutations in TAZ/WWTR1, a co-activator of NKX2.1 and PAX8 are not a frequent cause of thyroid dysgenesis

P. Macchia, M. Zannini, G. Fenzi, 2009, Journal of endocrinological investigation.

Thyroid autoantigens and their relevance in the pathogenesis of thyroid autoimmunity.

C. Marcocci, A. Pinchera, F. Santini, 1989, Biochimie.

Recent advances in the understanding of humoral and cellular mechanisms implicated in thyroid autoimmune disorders.

C. Marcocci, A. Pinchera, L. Chiovato, 1989, Clinical immunology and immunopathology.

A novel NKX2.1 mutation in a family with hypothyroidism and benign hereditary chorea.

P. Macchia, G. De Michele, A. Filla, 2008, Thyroid : official journal of the American Thyroid Association.

Increased level of thyroglobulin mRNA in a human familial goiter

C. Marcocci, A. Pinchera, L. Chiovato, 1987, Journal of endocrinological investigation.

Long-Term Interferon-α Therapy Does Not Affect Sex Hormones in Males with Chronic Hepatitis C

A. Mariano, M. Vitale, G. Fenzi, 1997 .

A new case of familial nonautoimmune hyperthyroidism caused by the M463V mutation in the TSH receptor with anticipation of the disease across generations: a possible role of iodine supplementation.

P. Macchia, G. Fenzi, M. Salerno, 2007, Thyroid : official journal of the American Thyroid Association.

Screening for mutations in the ISL1 gene in patients with thyroid dysgenesis

P. Macchia, I. C. Nettore, G. Fenzi, 2011, Journal of endocrinological investigation.

Prenyltransferase Inhibitors Induce Apoptosis in Proliferating Thyroid Cells through a p53-Independent, CrmA-Sensitive, and Caspase-3-Like Protease- Dependent Mechanism.

M. Vitale, G. Fenzi, G. Rossi, 1999, Endocrinology.

Assays of TSH-receptor antibodies in 576 patients with various thyroid disorders: their incidence, significance and clinical usefulness.

F. Cetani, A. Pinchera, G. Fenzi, 1989, Autoimmunity.

Thyroid-stimulating antibody mimics thyrotropin in its ability to desensitize the adenosine 3',5'-monophosphate response to acute stimulation in continuously cultured rat thyroid cells (FRT-L5).

A. Pinchera, L. Chiovato, P. Vitti, 1986, The Journal of clinical endocrinology and metabolism.

T cell subsets and thyroid-stimulating antibodies in patients with Graves’ disease in clinical remission

G. Fenzi, G. Ciprandi, M. Bagnasco, 1986, Journal of endocrinological investigation.

The HMG-CoA reductase inhibitor lovastatin induces apoptosis in proliferating human thyroid cells.

M. Vitale, G. Fenzi, G. Rossi, 1998 .

[Treatment of hot thyroid nodule with percutaneous ethanol injection. Our experience].

G. Lupoli, G. Fenzi, G. Lombardi, 1993, Minerva endocrinologica.

Combined analysis of galectin-3 and BRAFV600E improves the accuracy of fine-needle aspiration biopsy with cytological findings suspicious for papillary thyroid carcinoma.

G. Troncone, M. Sapio, Anna Guerra, 2007, Endocrine-related cancer.

Screening of thyrotropin receptor mutations by fine-needle aspiration biopsy in autonomous functioning thyroid nodules in multinodular goiters.

E. Papini, A. Porcellini, A. Pizzuti, 1999, Thyroid : official journal of the American Thyroid Association.

Orbital scintigraphy with [111In-diethylenetriamine pentaacetic acid-D-phe1]-octreotide predicts the clinical response to corticosteroid therapy in patients with Graves' ophthalmopathy.

P. Macchia, A. Colao, G. Fenzi, 1998, The Journal of clinical endocrinology and metabolism.

Intercellular adhesion molecule-1 is upregulated via the protein kinase C pathway in human thyroid carcinoma cell lines.

G. Fenzi, G. Rossi, M. Altomonte, 1998, Thyroid : official journal of the American Thyroid Association.

Retinoic acid induces intercellular adhesion molecule-1 hyperexpression in human thyroid carcinoma cell lines.

M. Vitale, G. Fenzi, G. Rossi, 1995, The Journal of clinical endocrinology and metabolism.

Thyroglobulin inhibition of thyrotropin binding to thyroid plasma membrane.

G. Fenzi, K. Hashizume, L. Degroot, 1978, The Journal of clinical endocrinology and metabolism.

Cell-to-cell contact modulates the expression of the beta 1 family of integrins in primary cultures of thyroid cells.

M. Illario, M. Vitale, G. Fenzi, 1995, Experimental cell research.

Mutations in the gene encoding thyroid transcription factor-1 (TTF-1) are not a frequent cause of congenital hypothyroidism (CH) with thyroid dysgenesis.

P. Macchia, D. Larizza, R. Lauro, 1997, Thyroid : official journal of the American Thyroid Association.

Expression of integrins of the β1 family in thyroid cells from patients with Graves' disease in vivo and in vitro

M. Vitale, S. Salzano, G. Fenzi, 1999 .

Loss of polarity and De novo expression of the β1 family of integrins in thyroid tumors

M. Illario, M. Vitale, G. Fenzi, 1994, International journal of cancer.

Graves’ IgG stimulation of continuously cultured rat thyroid cells: a sensitive and potentially useful clinical assay

A. Pinchera, P. Vitti, G. Fenzi, 1982, Journal of endocrinological investigation.

COMPARISON BETWEEN THYROID STIMULATING AND TSH‐BINDING INHIBITING IMMUNOGLOBULINS OF GRAVES' DISEASE

A. Pinchera, P. Vitti, L. Bartalena, 1981, Clinical endocrinology.

Effects of antithyroid therapy on the long-acting thyroid stimulator and the antithyroglobulin antibodies.

A. Pinchera, E. Martino, G. Fenzi, 1969, The Journal of clinical endocrinology and metabolism.

Recombinant thyrotropin-induced orbital uptake of [111In-diethylenetriamine-pentacetic acid-D-Phe1]octreotide in a patient with inactive Graves' ophthalmopathy.

M. Salvatore, A. Colao, G. Fenzi, 2005, The Journal of clinical endocrinology and metabolism.

The different cardiac expression of the type 2 iodothyronine deiodinase gene between human and rat is related to the differential response of the Dio2 genes to Nkx-2.5 and GATA-4 transcription factors.

C. Morisco, M. Vitale, G. Fenzi, 2003, Molecular endocrinology.

Fibronectin-Induced Proliferation in Thyroid Cells Is Mediated by αvβ3 Integrin through Ras/Raf-1/MEK/ERK and Calcium/CaMKII Signals

Maddalena Illario, Mario Vitale, Giancarlo Troncone, 2005 .

Graves’ disease and Turner’s syndrome

Elena S. Di Martino, C. Marcocci, A. Pinchera, 1980, Journal of endocrinological investigation.

Serum thyroglobulin in newborns’ cord blood, in childhood and adolescence: a physiological indicator of thyroidal status

A. Pinchera, G. Fenzi, F. Pacini, 1984, Journal of endocrinological investigation.

Serum thyroglobulin determinations in the differential diagnosis of congenital hypothyroidism

A. Pinchera, G. Fenzi, F. Pacini, 1984, Journal of endocrinological investigation.

RECIPROCAL CHANGES OF SERUM THYROGLOBULIN AND TSH IN RESIDENTS OF A MODERATE ENDEMIC GOITRE AREA

A. Pinchera, L. Bartalena, G. Fenzi, 1985, Clinical endocrinology.

Immunoglobulin binding of thyroid hormones in a case of Waldenstrom's macroglobulinemia.

F. Trimarchi, S. Mariotti, S. Benvenga, 1982, The Journal of clinical endocrinology and metabolism.

Expression of thyrotropin-receptor mRNA in healthy and Graves' disease retro-orbital tissue

A. Porcellini, G. Fenzi, A. Feliciello, 1993, The Lancet.

Thyroid function and morphology after a successful kidney transplantation

M. Sabbatini, S. Federico, F. Orio, 2006, Journal of endocrinological investigation.

Mutations of thyrotropin receptor gene

A. Porcellini, E. Avvedimento, G. Fenzi, 1997, Journal of Molecular Medicine.

A reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of Graves’ hyperthyroidism

C. Marcocci, G. Fenzi, C. Ceccarelli, 1990, Journal of endocrinological investigation.

Cardiovascular safety of acute recombinant human thyrotropin administration to patients monitored for differentiated thyroid cancer.

M. Salvatore, L. Pagano, B. Biondi, 2003, The Journal of clinical endocrinology and metabolism.

Calcium-calmodulin-dependent kinase II (CaMKII) mediates insulin-stimulated proliferation and glucose uptake.

M. Illario, B. Trimarco, P. Formisano, 2009, Cellular signalling.

Pendrin Is a Novel In Vivo Downstream Target Gene of the TTF-1/Nkx-2.1 Homeodomain Transcription Factor in Differentiated Thyroid Cells

M. Zannini, R. Nitsch, R. di Lauro, 2005, Molecular and Cellular Biology.

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

Luca Chiovato, P. Macchia, R. Lauro, 1998, Nature Genetics.

Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA).

G. Troncone, M. Sapio, M. Vitale, 2006, European journal of endocrinology.

Laminin receptors in differentiated thyroid tumors: restricted expression of the 67-kilodalton laminin receptor in follicular carcinoma cells.

M. Vitale, G. Fenzi, G. Rossi, 1999, The Journal of clinical endocrinology and metabolism.

Chapter 94 – Genetic Defects in Thyroid Hormone Synthesis and Action∗

P. Macchia, G. Fenzi, 2016 .

GENETIC DEFECTS IN THYROID HORMONE SUPPLY

P. Macchia, I. C. Nettore, G. Fenzi, 2014 .

Cloning, chromosomal localization and identification of polymorphisms in the human thyroid transcription factor 2 gene (TITF2).

P. Macchia, M. Mattei, R. di Lauro, 1999, Biochimie.

Thyroid autoimmunity and thyroid autonomy.

C. Marcocci, A. Pinchera, L. Chiovato, 1990, Acta medica Austriaca.

Role of autoimmune and familial factors in goiter prevalence. Studies performed in a moderately endemic area

A. Pinchera, P. Vitti, L. Bartalena, 1986, Journal of endocrinological investigation.

Revised Guidelines for Neonatal Screening Programmes for Primary Congenital Hypothyroidism

R. Fahlbusch, N. Skakkebæk, H. Dörr, 1999, Hormone Research in Paediatrics.

Studies on thyroid cell surface antigens using cultured human thyroid cells.

C. Marcocci, A. Pinchera, L. Chiovato, 1982, Clinical and experimental immunology.

The Ca2+-calmodulin-dependent kinase II is activated in papillary thyroid carcinoma (PTC) and mediates cell proliferation stimulated by RET/PTC.

M. Illario, M. Santoro, P. Campiglia, 2010, Endocrine-related cancer.

GENETIC DEFECTS IN THYROID HORMONE SUPPLY Immacolata

P. Macchia, G. Fenzi, Cristina Nettore, 2018 .

High-dose intravenous corticosteroid therapy for Graves’ ophthalmopathy

P. Macchia, G. Vitale, M. Vitale, 2001, Journal of endocrinological investigation.

Novel mutations of thyrotropin receptor gene in thyroid hyperfunctioning adenomas. Rapid identification by fine needle aspiration biopsy.

A. Porcellini, L. Laviola, G. Fenzi, 1994, The Journal of clinical endocrinology and metabolism.

Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells

A. Porcellini, E. Avvedimento, G. Fenzi, 1997, Oncogene.

DEMONSTRATION OF BLOCKING IMMUNOGLOBULINS G, HAVING A HETEROGENEOUS BEHAVIOUR, IN SERA OF PATIENTS WITH GRAVES' DISEASE: POSSIBLE COEXISTENCE OF DIFFERENT AUTOANTIBODIES DIRECTED TO THE TSH RECEPTOR

A. Pinchera, G. Fenzi, G. Carone, 1988, Clinical endocrinology.

Iodized salt prophylaxis of endemic goiter: an experience in Toscana (Italy).

A. Pinchera, T. Rago, P. Vitti, 1993, Acta endocrinologica.

Clinical implications of somatostatin-receptor scintigraphy in ophthalmic Graves' disease.

A. Faggiano, A. Colao, G. Fenzi, 2000, European journal of endocrinology.

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins.

G. Chiappetta, M. Barone, M. Santoro, 2000, The Journal of clinical endocrinology and metabolism.

Increased prevalence of thyroid autoimmunity in patients successfully treated for Cushing's disease

P. Marzullo, A. Faggiano, G. Fenzi, 2000, Clinical endocrinology.

Identification and functional characterization of a novel mutation in the NKX2-1 gene: comparison with the data in the literature.

P. Macchia, I. C. Nettore, F. Beguinot, 2013, Thyroid : official journal of the American Thyroid Association.

Percutaneous ethanol injection under Power Doppler ultrasound assistance in the treatment of autonomously functioning thyroid nodules

P. Marzullo, A. Colao, G. Fenzi, 1999, Journal of endocrinological investigation.

Power Doppler Improves the Diagnostic Accuracy of Color Doppler Ultrasonography in Cold Thyroid Nodules: Follow-Up Results

A. Colao, G. Fenzi, G. Lombardi, 1999, Hormone Research in Paediatrics.

Incidence of antibodies blocking thyrotropin effect in vitro in patients with euthyroid or hypothyroid autoimmune thyroiditis.

A. Pinchera, F. Santini, L. Chiovato, 1990, The Journal of clinical endocrinology and metabolism.

Do glucocorticoids affect outcome in Graves' disease following radioiodine therapy?

G. Fenzi, D. Salvatore, 2006, Nature Clinical Practice Endocrinology &Metabolism.

TSH-Blocking Antibodies and Congenital Hypothyroidism

C. Marcocci, A. Pinchera, F. Santini, 1989 .

SIGNIFICANCE OF THYROID AUTOANTIBODIES IN AUTOIMMUNE THYROID DISEASES

A. Pinchera, L. Chiovato, P. Vitti, 1985 .

Radio-receptor assay of TSH: its use to detect thyroid-stimulating immunoglobulins

L. Bartalena, G. Fenzi, L. Degroot, 1978, Journal of endocrinological investigation.

A sensitive method for assaying thyroid stimulating immunoglobulins of Graves' disease: use of the guanyl nucleotide-amplified thyroid adenylate cyclase assay.

A. Pinchera, G. Fenzi, P. Carayon, 1983, Acta endocrinologica.

Incidence of TSH Receptor Antibodies in Patients with Toxic Diffuse

A. Pinchera, G. Fenzi, G. Carone, 1987 .

Radioimmunological studies on the long-acting thyroid stimulator.

A. Pinchera, E. Martino, G. Fenzi, 1970, Endocrinology.

TSH-displacing activity versus TSH-binding inhibiting activity of immunoglobulins from patients with Graves’ disease

A. Pinchera, L. Bartalena, G. Fenzi, 1983, Journal of endocrinological investigation.

Thyroid-stimulating immunoglobulins.

A. Pinchera, L. Bartalena, S. Mariotti, 1982, Hormone research.

Predictive Use of Tsh-Receptor Antibodies Assay as a Prognostic Index in Graves’ Patients Treated with Antithyroid Drugs or Radioactive-Iodine

A. Pinchera, G. Fenzi, G. Carone, 1987 .

Clinical approach to goitre.

C. Marcocci, A. Pinchera, F. Aghini‐Lombardi, 1988, Bailliere's clinical endocrinology and metabolism.

Autoantibodies Stimulating Thyroid Growth and Adenylate Cyclase Cannot be Separated in IgGs From Patients with Active Graves’ Disease

C. Marcocci, A. Pinchera, L. Chiovato, 1987 .

Role of the adenylate cyclase-cAMP system on TSH-stimulated thyroid cell growth.

C. Marcocci, G. Fenzi, E. Grollman, 1987, Acta endocrinologica. Supplementum.

SCREENING FOR RISK OF DELIVERY OF A HYPOTHYROID BABY

C. Marcocci, A. Pinchera, L. Chiovato, 1986, The Lancet.

Interaction of the thyrotropin receptor on rat FRTL-5 thyroid cells with thyrotropin and a thyrotropin-stimulating autoantibody from Graves' patients.

A. Pinchera, L. Chiovato, P. Vitti, 1987, Biochemical and biophysical research communications.

Blocking-Antibodies Apparently Without Any Stimulatory Activity are Present in Sera of Patients with Graves’ Disease

A. Pinchera, G. Fenzi, G. Carone, 1987 .

Interference of thyroglobulin in TSAb detection by radio-receptor assay

L. Bartalena, G. Fenzi, F. Monzani, 1979, Journal of endocrinological investigation.

Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B.

M. Santoro, A. Fusco, R. Melillo, 2001, Cancer research.

Can the inhibition of prostaglandin synthesis affect the adenylate cyclase response to thyroid stimulating antibodies?

A. Pinchera, G. Fenzi, E. Macchia, 1985, Journal of endocrinological investigation.

Free thyroxine values in dried blood spots on filter paper in newborns are related to both gestational age and birth body weight

A. Pinchera, L. Chiovato, L. Bartalena, 1988, Journal of endocrinological investigation.

Reply: Letters to the Editors

A. Faggiano, A. Colao, G. Fenzi, 2001 .

Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression

M. Vitale, G. Fenzi, G. Rossi, 1999, FEBS letters.

[Widespread endemic goiter and iodine deficiency in the province of Avellino].

P. Macchia, M. Vitale, G. Fenzi, 1998, Annali dell'Istituto superiore di sanita.

Long-term interferon-alpha therapy does not affect sex hormones in males with chronic hepatitis C.

A. Mariano, M. Vitale, G. Fenzi, 1997, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Somatic mutations in the VI transmembrane segment of the thyrotropin receptor constitutively activate cAMP signalling in thyroid hyperfunctioning adenomas.

A. Porcellini, G. Fenzi, S. Pannain, 1995, Oncogene.

CLINICAL CASE SEMINAR Recombinant Thyrotropin-Induced Orbital Uptake of [ 111 In-Diethylenetriamine-Pentacetic Acid- D Phe 1 ]Octreotide in a Patient with Inactive Graves’ Ophthalmopathy

M. Salvatore, A. Colao, G. Fenzi, 2005 .

Evaluation of L-thyroxine replacement therapy in children with congenital hypothyroidism

A. Pinchera, L. Chiovato, M. Tonacchera, 1991, Journal of endocrinological investigation.

Fibronectin-induced proliferation in thyroid cells is mediated by alphavbeta3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals.

Maddalena Illario, Mario Vitale, Giancarlo Troncone, 2005, The Journal of clinical endocrinology and metabolism.

Measurement of TSAb directly in serum using FRTL-5 cells

A. Pinchera, F. Santini, L. Chiovato, 1988, Journal of endocrinological investigation.

Amiodarone induces cytochrome c release and apoptosis through an iodine-independent mechanism.

F. Bogazzi, E. Martino, M. Vitale, 2000, The Journal of clinical endocrinology and metabolism.

European Thyroid Association: 2006 in Naples.

G. Fenzi, G. Vecchio, 2006, Thyroid : official journal of the American Thyroid Association.

Integrin binding to immobilized collagen and fibronectin stimulates the proliferation of human thyroid cells in culture.

M. Illario, M. Vitale, G. Fenzi, 1997, Endocrinology.

The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Serum Withdrawal-Induced Apoptosis in Thyroid Cells Is Caused by Loss of Fibronectin-Integrin Interaction*

M. Vitale, G. Fenzi, G. Rossi, 2022 .

Fibronectin is required to prevent thyroid cell apoptosis through an integrin-mediated adhesion mechanism.

M. Illario, M. Vitale, G. Fenzi, 1998, The Journal of clinical endocrinology and metabolism.

The primary occurrence of BRAF(V600E) is a rare clonal event in papillary thyroid carcinoma.

V. Marotta, M. Sapio, Anna Guerra, 2012, The Journal of clinical endocrinology and metabolism.

Growing thyroid nodules with benign histology and RET rearrangement.

V. Marotta, M. Sapio, Anna Guerra, 2010, Endocrine journal.