A. Douar

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Reversal of Type 1 Diabetes by Engineering a Glucose Sensor in Skeletal Muscle

F. Bosch, A. Mas, J. Montane, 2006, Diabetes.

Intracellular Trafficking of Adeno-Associated Virus Vectors: Routing to the Late Endosomal Compartment and Proteasome Degradation

O. Danos, A. Douar, K. Poulard, 2001, Journal of Virology.

Gene therapy for rheumatoid arthritis

C. Jorgensen, A. Douar, M. Mezzina, 2002, The journal of gene medicine.

Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons.

J. Fyfe, A. Douar, M. Colle, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus

A. Douar, C. Coutelle, A. Pavirani, 1997, Gene Therapy.

Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B

A. Douar, C. Coutelle, A. Pavirani, 1999, The journal of gene medicine.

Optogenetic therapy: High spatiotemporal resolution and pattern recognition compatible with vision restoration in non-human primates

O. Marre, J. Sahel, F. Arcizet, 2020, bioRxiv.

Comparative efficacy of intratracheal adeno-associated virus administration to newborn rats.

C. Delacourt, O. Danos, A. Douar, 2005, Human gene therapy.

Deleterious effect of peptide insertions in a permissive site of the AAV2 capsid.

O. Danos, A. Douar, K. Poulard, 2003, Virology.

High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson’s disease

B. Bénichou, A. Douar, G. González-Aseguinolaza, 2022, Molecular therapy. Methods & clinical development.

Adrenoleukodystrophy: a complex chromosomal rearrangement in the Xq28 red/green-color-pigment gene region indicates two possible gene localizations.

D. Le Paslier, J. Mosser, J. Mandel, 1991, American journal of human genetics.

Cells for Gene Therapy and Vector Production

A. Douar, M. Chillón, O. Merten, 2007 .

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis

A. Buj-Bello, P. Denéfle, A. Beggs, 2008, Human molecular genetics.

Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice

O. Danos, A. Douar, C. Rivière, 2006, Gene Therapy.

Major Subsets of Human Dendritic Cells Are Efficiently Transduced by Self-Complementary Adeno-Associated Virus Vectors 1 and 2

A. Douar, V. Allo, P. Véron, 2007, Journal of Virology.

Optimising the IgG‐degrading enzyme treatment regimen for enhanced adeno‐associated virus transduction in the presence of neutralising antibodies

B. Bénichou, A. Douar, G. González-Aseguinolaza, 2022, Clinical & translational immunology.

Use of an adeno‐associated virus serotype Anc80 to provide durable cure of phenylketonuria in a mouse model

R. A. Kaiser, A. Douar, G. González-Aseguinolaza, 2021, Journal of inherited metabolic disease.

Use of an AAV serotype Anc80 to provide durable cure of phenylketonuria in a mouse model

R. A. Kaiser, A. Douar, L. Trigueros-Motos, 2021 .

The challenge of fetal gene therapy

W. Colledge, A. Douar, C. Coutelle, 1995, Nature Medicine.

Adeno-associated virus pseudotype 5 vector improves gene transfer in arthritic joints.

P. Tak, P. Tak, O. Danos, 2005, Human gene therapy.

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.

Terence R Flotte, Hiroaki Mizukami, Mauro Giacca, 2010, Human gene therapy.

X-linked adrenoleukodystrophy gene: identification of a candidate gene by positional cloning.

J. Mosser, J. Mandel, A. Douar, 1994, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Current issues in adeno-associated viral vector production

A. Douar, O. Merten, O-W Merten, 2005, Gene Therapy.

Adeno-Associated Virus: A Promising Tool for Gene Delivery

A. Douar, 2000 .

Fetal somatic gene therapy.

A. Douar, C. Coutelle, M. Themis, 1996, Molecular human reproduction.

The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein.

J. Mosser, J. Mandel, A. Douar, 1994, Human molecular genetics.

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

Jean Mosser, Hugo Moser, Jean-Louis Mandel, 1993, Nature.

Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis.

J. Mosser, J. Mandel, A. Douar, 1993, Biochimie.

Abnormal messenger RNA expression and a missense mutation in patients with X-linked adrenoleukodystrophy.

J. Mosser, J. Mandel, A. Douar, 1993, Human molecular genetics.

Gene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model

B. Bénichou, A. Douar, G. González-Aseguinolaza, 2019, Nature Communications.

Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates

O. Marre, J. Sahel, F. Arcizet, 2021, Communications Biology.

Gene Therapy Progress and Prospects – Vectorology: design and production of expression cassettes in AAV vectors

A. Douar, C. L. Bec, AM Douar, 2006, Gene Therapy.

Effect of amniotic fluid on cationic lipid mediated transfection and retroviral infection.

V. Sandig, T. Friedmann, A. Douar, 1996, Gene therapy.

Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for.

C. Rodeck, A. Douar, C. Coutelle, 2001, Ernst Schering Research Foundation workshop.

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.

L. Zentilin, M. Giacca, T. Conlon, 2010, Human gene therapy.