G. Kaatz

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Role of Multidrug Efflux Pumps in Gram-Positive Bacteria

G. Kaatz, 2005 .

A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus.

G. Kaatz, S. Gibbons, Moyosoluwa Oluwatuyi, 2003, The Journal of antimicrobial chemotherapy.

A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus.

D. Livermore, S. Neidle, M. Gunaratnam, 2013, International journal of antimicrobial agents.

Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus

G. Kaatz, S. M. Seo, 1997, Antimicrobial agents and chemotherapy.

Effects of NorA Inhibitors on In Vitro Antibacterial Activities and Postantibiotic Effects of Levofloxacin, Ciprofloxacin, and Norfloxacin in Genetically Related Strains ofStaphylococcus aureus

G. Kaatz, J. Aeschlimann, L. Dresser, 1999, Antimicrobial Agents and Chemotherapy.

Inhibition of bacterial efflux pumps: a new strategy to combat increasing antimicrobial agent resistance

G. Kaatz, 2002, Expert opinion on emerging drugs.

Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA.

G. Cruciani, E. Carosati, M. Frosini, 2012, ACS medicinal chemistry letters.

Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus.

G. Kaatz, B. Schindler, S. M. Seo, 2012, International journal of antimicrobial agents.

Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development.

L. Goracci, G. Cruciani, G. Kaatz, 2017, Journal of medicinal chemistry.

Piperazinyl-linked fluoroquinolone dimers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus.

G. Kaatz, M. Rybak, R. Kerns, 2003, Bioorganic & medicinal chemistry letters.

Inducible NorA-mediated multidrug resistance in Staphylococcus aureus

G. Kaatz, S. M. Seo, 1995, Antimicrobial agents and chemotherapy.

Mechanism of ciprofloxacin resistance in Pseudomonas aeruginosa.

G. Kaatz, S. M. Seo, 1988, The Journal of infectious diseases.

Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus

G. Kaatz, S. M. Seo, C. Kosmidis, 2010, Antimicrobial Agents and Chemotherapy.

Treatment strategies for infective endocarditis

G. Kaatz, T. Chopra, Teena Chopra, 2010, Expert opinion on pharmacotherapy.

Characteristics of Patients With Healthcare-Associated Infection Due to SCCmec Type IV Methicillin-Resistant Staphylococcus aureus

G. Kaatz, M. Amjad, M. Rybak, 2006, Infection Control & Hospital Epidemiology.

Oxazolidinones: new players in the battle against multi-resistant Gram-positive bacteria

G. Kaatz, M. Rybak, M. Rybak, 2001, Expert opinion on emerging drugs.

Evaluation of Daptomycin Non-Susceptible Staphylococcus aureus for Stability, Population Profiles, mprF Mutations, and Daptomycin Activity

K. Kaye, G. Kaatz, M. Rybak, 2013, Infectious Diseases and Therapy.

Characterizing Vancomycin-Resistant Enterococcus Strains with Various Mechanisms of Daptomycin Resistance Developed in an In Vitro Pharmacokinetic/Pharmacodynamic Model

G. Kaatz, M. Rybak, W. Rose, 2011, Antimicrobial Agents and Chemotherapy.

Evaluation of dalbavancin, tigecycline, minocycline, tetracycline, teicoplanin and vancomycin against community-associated and multidrug-resistant hospital-associated meticillin-resistant Staphylococcus aureus.

G. Kaatz, M. Rybak, Chrissy M. Cheung, 2010, International journal of antimicrobial agents.

Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents.

Brian T. Tsuji, G. Kaatz, M. Amjad, 2007, Diagnostic microbiology and infectious disease.

Fluoroquinolone Resistance in Streptococcus pneumoniae: Area Under the Concentration-Time Curve/MIC Ratio and Resistance Development with Gatifloxacin, Gemifloxacin, Levofloxacin, and Moxifloxacin

Brian T. Tsuji, G. Kaatz, M. Rybak, 2007, Antimicrobial Agents and Chemotherapy.

Enzyme induction by phenobarbitone and vitamin K1 disposition in man.

G. Kaatz, B. K. Park, E. Ohnhaus, 1984, British journal of clinical pharmacology.

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.

G. Kaatz, S. Sabatini, G. Manfroni, 2013, Journal of medicinal chemistry.

Searching for innovative quinolone-like scaffolds: synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives

G. Kaatz, Marco Pieroni, S. Sabatini, 2012 .

Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.

E. Carosati, G. Kaatz, M. Villarini, 2012, Journal of medicinal chemistry.

Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.

G. Kaatz, S. Sabatini, D. Patel, 2011, Journal of medicinal chemistry.

Fluoroquinolone Resistance in Bacteria

G. Kaatz, V. Moudgal, 2009 .

Indole Based Weapons to Fight Antibiotic Resistance: A Structure-Activity Relationship Study.

L. Goracci, G. Cruciani, G. Kaatz, 2016, Journal of medicinal chemistry.

Activities of Mutant Prevention Concentration-Targeted Moxifloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model

G. Kaatz, M. Rybak, G. Allen, 2003, Antimicrobial Agents and Chemotherapy.

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors.

G. Kaatz, D. Pietrella, S. Sabatini, 2017, Journal of medicinal chemistry.

Development of resistance to fleroxacin during therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditis

G. Kaatz, S. M. Seo, M. Rybak, 1991, Antimicrobial Agents and Chemotherapy.

Pharmacodynamics of levofloxacin, ofloxacin, and ciprofloxacin, alone and in combination with rifampin, against methicillin-susceptible and -resistant Staphylococcus aureus in an in vitro infection model

G. Kaatz, S. M. Seo, M. Rybak, 1994, Antimicrobial Agents and Chemotherapy.

Introduction of a norA Promoter Region Mutation into the Chromosome of a Fluoroquinolone-Susceptible Strain ofStaphylococcus aureus Using Plasmid Integration

G. Kaatz, T. Foster, S. M. Seo, 1999, Antimicrobial Agents and Chemotherapy.

Synergy between gemifloxacin and trimethoprim/sulfamethoxazole against community-associated methicillin-resistant Staphylococcus aureus.

G. Kaatz, M. Rybak, Steven N. Leonard, 2008, The Journal of antimicrobial chemotherapy.

Synergy between gemiﬂoxacin and trimethoprim/sulfamethoxazole against community-associated methicillin-resistant Staphylococcus aureus

G. Kaatz, Michael J. Rybak, Steven N. Leonard, 2008 .

Antimicrobial Susceptibility and Staphylococcal Chromosomal Cassette mec Type in Community‐ and Hospital‐Associated Methicillin‐Resistant Staphylococcus aureus

G. Kaatz, M. Amjad, M. Rybak, 2007, Pharmacotherapy.

From phenothiazine to 3-phenyl-1,4-benzothiazine derivatives as inhibitors of the Staphylococcus aureus NorA multidrug efflux pump.

G. Kaatz, G. Rossolini, S. Sabatini, 2008, Journal of medicinal chemistry.

The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.

G. Kaatz, J. Aeschlimann, M. Rybak, 1999, The Journal of antimicrobial chemotherapy.

Multidrug efflux pumps of Gram-positive bacteria.

G. Kaatz, B. Schindler, 2016, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Structural differences between paroxetine and femoxetine responsible for differential inhibition of Staphylococcus aureus efflux pumps.

G. Kaatz, P. Wei, R. Kerns, 2004, Bioorganic & medicinal chemistry letters.

The Molecular Mechanisms of Allosteric Mutations Impairing MepR Repressor Function in Multidrug-Resistant Strains of Staphylococcus aureus

R. Brennan, G. Kaatz, B. Schindler, 2013, mBio.

The emergence of resistance to ciprofloxacin during treatment of experimental Staphylococcus aureus endocarditis.

G. Kaatz, S. Barriere, D. Schaberg, 1987, The Journal of antimicrobial chemotherapy.

Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.

G. Kaatz, N. Cech, Hiyas A. Junio, 2011, Planta medica.

Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline.

V. Nizet, R. Kullar, J. Pogliano, 2014, Clinical therapeutics.

Efficacy of ofloxacin in experimental Staphylococcus aureus endocarditis

G. Kaatz, S. M. Seo, M. Rybak, 1990, Antimicrobial Agents and Chemotherapy.

A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition

Daniel H. Foil, G. Kaatz, N. Cech, 2015, PloS one.

Evaluation of Ceftaroline Activity against Heteroresistant Vancomycin-Intermediate Staphylococcus aureus and Vancomycin-Intermediate Methicillin-Resistant S. aureus Strains in an In Vitro Pharmacokinetic/Pharmacodynamic Model: Exploring the “Seesaw Effect”

G. Kaatz, M. Rybak, B. Werth, 2013, Antimicrobial Agents and Chemotherapy.

Evaluation of Ceftaroline (CPT) Activity Against Heteroresistant Vancomycin 1 Intermediate Staphylococcus aureus (hVISA) and VISA Methicillin-Resistant S. 2 aureus (MRSA) Strains in an In Vitro Pharmacokinetic/Pharmacodynamic (PK/PD) 3 Model: Exploring the “Seesaw Effect”

G. Kaatz, Michael J. Rybak, B. Werth, 2013 .

Impact of Inoculum Size and Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA) on Vancomycin Activity and Emergence of VISA in an In Vitro Pharmacodynamic Model

G. Kaatz, M. Rybak, Steven N. Leonard, 2008, Antimicrobial Agents and Chemotherapy.

G. Kaatz, B. Schindler, S. M. Seo, 2015, International journal of antimicrobial agents.

Pharmacodynamics of RP 59500 (quinupristin-dalfopristin) administered by intermittent versus continuous infusion against Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model

G. Kaatz, M. Rybak, R. Mercier, 1997, Antimicrobial agents and chemotherapy.

Pharmacokinetics and bactericidal rates of daptomycin and vancomycin in intravenous drug abusers being treated for gram-positive endocarditis and bacteremia

G. Kaatz, E. Bailey, M. Rybak, 1992, Antimicrobial Agents and Chemotherapy.

Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus

N. Martins, H. Coutinho, G. Kaatz, 2020, Antibiotics.

In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis

G. Kaatz, S. M. Seo, 1996, Antimicrobial agents and chemotherapy.

Pharmacodynamics ofLevofloxacin, Ofloxacin, andCiprofloxacin, AloneandinCombination withRifampin, against Methicillin- Susceptible and-Resistant Staphylococcus aureus inan InVitro Infection Model

G. Kaatz, S. L. Kang, 1994 .

Mechanisms of fluoroquinolone resistance in Staphylococcus aureus.

G. Kaatz, S. M. Seo, C. A. Ruble, 1991, The Journal of infectious diseases.

Development ofResistance toFleroxacin during Therapy ofExperimental Methicillin-Susc eptible Staphylococcus aureus Endocarditis

G. Kaatz, M. Rybak, 1991 .

Ciprofloxacin and rifampin, alone and in combination, for therapy of experimental Staphylococcus aureus endocarditis

G. Kaatz, S. M. Seo, M. Rybak, 1989, Antimicrobial Agents and Chemotherapy.

Ciprofloxacin versus vancomycin in the therapy of experimental methicillin-resistant Staphylococcus aureus endocarditis

G. Kaatz, S. Barriere, D. Schaberg, 1987, Antimicrobial Agents and Chemotherapy.

Analyses of Multidrug Efflux Pump-Like Proteins Encoded on the Staphylococcus aureus Chromosome

G. Kaatz, B. Schindler, S. M. Seo, 2014, Antimicrobial Agents and Chemotherapy.

In vitro pharmacodynamic effects of concentration, pH, and growth phase on serum bactericidal activities of daptomycin and vancomycin

G. Kaatz, E. Bailey, M. Rybak, 1992, Antimicrobial Agents and Chemotherapy.

Discovery of novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.

Stefano Sabatini, Gabriele Cruciani, Emanuele Carosati, 2011, Journal of medicinal chemistry.

Inhibition of the NorA multi-drug transporter by oxygenated monoterpenes.

G. Kaatz, J. P. de Siqueira Júnior, H. M. Barreto, 2016, Microbial pathogenesis.

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps.

G. Kaatz, P. Wei, N. German, 2008, European journal of medicinal chemistry.

Structural features of piperazinyl-linked ciprofloxacin dimers required for activity against drug-resistant strains of Staphylococcus aureus.

G. Kaatz, M. Rybak, R. Kerns, 2003, Bioorganic & medicinal chemistry letters.

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3‐Phenyl‐1,4‐benzothiazine Analogues

G. Kaatz, B. Schindler, S. Sabatini, 2017, ChemMedChem.

The Phenolic Diterpene Totarol Inhibits Multidrug Efflux Pump Activity in Staphylococcus aureus

Simon Gibbons, G. Kaatz, S. Gibbons, 2007, Antimicrobial Agents and Chemotherapy.

Comparative In Vitro Activities and Postantibiotic Effects of the Oxazolidinone Compounds Eperezolid (PNU-100592) and Linezolid (PNU-100766) versus Vancomycin against Staphylococcus aureus, Coagulase-Negative Staphylococci, Enterococcus faecalis, and Enterococcus faecium

G. Kaatz, J. Aeschlimann, Michael J. Rybak, 1998, Antimicrobial Agents and Chemotherapy.

Emergence of teicoplanin resistance during therapy of Staphylococcus aureus endocarditis.

G. Kaatz, S. Lerner, S. M. Seo, 1990, The Journal of infectious diseases.

Efficacy of LY333328 against Experimental Methicillin-Resistant Staphylococcus aureus Endocarditis

G. Kaatz, S. M. Seo, J. Aeschlimann, 1998, Antimicrobial Agents and Chemotherapy.

Alternative mutational pathways to intermediate resistance to vancomycin in methicillin-resistant Staphylococcus aureus.

A. Tomasz, R. Tewhey, G. Kaatz, 2013, The Journal of infectious diseases.

Mechanisms of daptomycin resistance in Staphylococcus aureus.

G. Kaatz, T. Lundstrom, S. M. Seo, 2006, International journal of antimicrobial agents.

Efficacy of Trovafloxacin against Experimental Staphylococcus aureus Endocarditis

G. Kaatz, S. M. Seo, J. Aeschlimann, 1998, Antimicrobial Agents and Chemotherapy.

Multidrug Resistance in Staphylococcus aureus Due to Overexpression of a Novel Multidrug and Toxin Extrusion (MATE) Transport Protein

G. Kaatz, S. M. Seo, F. McAleese, 2005, Antimicrobial Agents and Chemotherapy.

From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps.

E. Carosati, G. Kaatz, Marco Pieroni, 2010, Journal of medicinal chemistry.

Antibacterial and resistance modifying activity of Rosmarinus officinalis.

G. Kaatz, S. Gibbons, Moyosoluwa Oluwatuyi, 2004, Phytochemistry.

Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana.

G. Kaatz, S. Gibbons, Eileen C. J. Smith, 2007, Phytochemistry.

Benzocyclohexane oxide derivatives and neolignans from Piper betle inhibit efflux-related resistance in Staphylococcus aureus

G. Kaatz, S. Gibbons, P. Khondkar, 2016 .

Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus

G. Kaatz, S. M. Seo, C. A. Ruble, 1993, Antimicrobial Agents and Chemotherapy.

Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.

M. Zloh, G. Kaatz, S. Gibbons, 2004, Bioorganic & medicinal chemistry letters.

Antimicrobial activity and inhibition of the NorA efflux pump of Staphylococcus aureus by extract and isolated compounds from Arrabidaea brachypoda.

G. Kaatz, C. D. da Rocha, Ana L. Portela, 2019, Microbial pathogenesis.

Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones

J. Rotschafer, G. Kaatz, R. A. Zabinski, 1995, Antimicrobial agents and chemotherapy.

Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in Staphylococcus aureus

G. Kaatz, J. Kristiansen, S. M. Seo, 2003, Antimicrobial Agents and Chemotherapy.

Bactericidal activities of teicoplanin, vancomycin, and gentamicin alone and in combination against Staphylococcus aureus in an in vitro pharmacodynamic model of endocarditis

G. Kaatz, M. Rybak, B. J. McGrath, 1994, Antimicrobial Agents and Chemotherapy.

Antimicrobial activity of Phyllanthus amarus Schumach. & Thonn and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin.

G. Kaatz, R. C. Dos Santos, L. M. Costa, 2019, Microbial pathogenesis.

Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

R. Brennan, M. Kumaraswami, G. Kaatz, 2009, Nucleic acids research.

Structural and biochemical characterization of MepR , a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump

R. Brennan, M. Kumaraswami, G. Kaatz, 2009 .

Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps.

G. Kaatz, N. German, R. Kerns, 2008, Bioorganic & medicinal chemistry letters.

Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus.

G. Kaatz, J. Kristiansen, S. M. Seo, 2003, International journal of antimicrobial agents.

Comparative effect of protein binding on the killing activities of teicoplanin and vancomycin

G. Kaatz, E. Bailey, M. Rybak, 1991, Antimicrobial Agents and Chemotherapy.

Efficacy of fleroxacin in experimental methicillin-resistant Staphylococcus aureus endocarditis

G. Kaatz, S. M. Seo, M. Rybak, 1989, Antimicrobial Agents and Chemotherapy.

Successful therapy of Pseudomonas aeruginosa endocarditis with ceftazidime and tobramycin.

G. Kaatz, A. Cabinian, 1987, The American journal of medicine.

Inhibition of the NorA efflux pump of Staphylococcus aureus by synthetic riparins

H. Coutinho, G. Kaatz, L. M. Costa, 2016, Journal of applied microbiology.

The multidrug efflux pump NorA is not required for salicylate-induced reduction in drug accumulation by Staphylococcus aureus.

G. Kaatz, J. Gustafson, C. Price, 2002, International journal of antimicrobial agents.

Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes

G. Kaatz, D. Arcanjo, A. M. Citó, 2019, Letters in applied microbiology.

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

G. Kaatz, A. Neyfakh, C. Borsch, 1993, Antimicrobial Agents and Chemotherapy.

Acquisition of Clostridium difficile from the hospital environment.

K. Wilson, G. Kaatz, S. M. Seo, 1988, American journal of epidemiology.

Bacterial efflux pump inhibition.

G. Kaatz, 2005, Current opinion in investigational drugs.

Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes.

G. Kaatz, S. M. Seo, Jose L. Raygada, 2008, Microbiology.

G. Kaatz, S. M. Seo, Emmanuel Frempong-Manso, 2007, Antimicrobial Agents and Chemotherapy.

Antibacterial Sesquiterpenoid Derivatives from Ferula ferulaeoides

G. Kaatz, S. Gibbons, Khadijo Osman, 2013, Planta Medica.

Inhibition of drug efflux pumps in Staphylococcus aureus: current status of potentiating existing antibiotics.

G. Kaatz, B. Schindler, P. Jacinto, 2013, Future microbiology.

N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors.

G. Kaatz, S. Gibbons, B. David, 2007, Bioorganic & medicinal chemistry letters.

Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus.

G. Kaatz, S. Gibbons, E. Moser, 2004, Planta medica.

Inhibition of drug efflux pumps in Staphylococcus aureus: current status for potentiating existing

G. Kaatz, B. Schindler, P. Jacinto, 2013 .

Evaluation of daptomycin treatment of Staphylococcus aureus bacterial endocarditis: an in vitro and in vivo simulation using historical and current dosing strategies.

G. Kaatz, M. Rybak, W. Rose, 2007, The Journal of antimicrobial chemotherapy.

Mechanisms of in-vitro-selected daptomycin-non-susceptibility in Staphylococcus aureus.

G. Kaatz, S. M. Seo, D. Patel, 2011, International journal of antimicrobial agents.

Efavirenz-Associated Urinary Matrix Stone-A Rare Presentation.

G. Kaatz, M. Mohanty, D. Abu-Hamdan, 2016, American Journal of the Medical Sciences.

Altered pharmacokinetic disposition of ciprofloxacin and vancomycin after single and multiple doses in rabbits

G. Kaatz, S. Barriere, D. Schaberg, 1987, Antimicrobial Agents and Chemotherapy.

Bactericidal Activities ofTeicoplanin, Vancomycin, andGentamicin AloneandinCombination against Staphylococcus aureus in anInVitro Pharmacodynamic ModelofEndocarditis

G. Kaatz, 1994 .

Identification and characterization of a novel efflux-related multidrug resistance phenotype in Staphylococcus aureus.

G. Kaatz, S. M. Seo, V. Moudgal, 2002, The Journal of antimicrobial chemotherapy.

Teicoplanin pharmacodynamics in reference to the accessory gene regulator (agr) in Staphylococcus aureus using an in vitro pharmacodynamic model.

G. Kaatz, M. Rybak, W. Rose, 2008, The Journal of antimicrobial chemotherapy.

Daptomycin Activity against Staphylococcus aureus following Vancomycin Exposure in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations

Warren E. Rose, Marcus J. Zervos, G. Kaatz, 2007, Antimicrobial Agents and Chemotherapy.

Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR

R. Brennan, G. Kaatz, B. Schindler, 2013, Nucleic acids research.

Correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus in reference to accessory gene regulator (agr) polymorphism and function.

G. Kaatz, M. Rybak, W. Rose, 2007, The Journal of antimicrobial chemotherapy.

Clinical isolates of Staphylococcus aureus from 1987 and 1989 demonstrating heterogeneous resistance to vancomycin and teicoplanin.

G. Kaatz, M. Rybak, Venkata G Meka, 2005, Diagnostic microbiology and infectious disease.

Inability of a reserpine-based screen to identify strains overexpressing efflux pump genes in clinical isolates of Staphylococcus aureus.

G. Kaatz, S. M. Seo, Jose L. Raygada, 2009, International journal of antimicrobial agents.

University of Southern Denmark Comparison of Antibacterial Activity of (-) Thioridazine and Racemic Thioridazine in Staphylococcus aureus

S. Fey, B. Kallipolitis, G. Kaatz, 2018 .

Comparison of Antibacterial Activity of (-) Thioridazine and Racemic Thioridazine in Staphylococcus aureus

S. Fey, B. Kallipolitis, G. Kaatz, 2018 .

Evidence for the Existence of a Multidrug Efflux Transporter Distinct from NorA in Staphylococcus aureus

M. Wahiduzzaman, G. Kaatz, T. Foster, 2000, Antimicrobial Agents and Chemotherapy.

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position.

G. Kaatz, B. Schindler, S. Sabatini, 2018, European journal of medicinal chemistry.

The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives.

G. Kaatz, W. Lindner, B. Natalini, 2016, Journal of Pharmaceutical and Biomedical Analysis.

Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump

G. Kaatz, B. Schindler, S. M. Seo, 2012, Journal of bacteriology.

In silico genetic correlations of multidrug efflux pump gene expression in Staphylococcus aureus.

G. Kaatz, S. M. Seo, C. Kosmidis, 2010, International journal of antimicrobial agents.

The Phenolic Diterpene Totarol Inhibits Multidrug Efﬂux Pump Activity in Staphylococcus aureus (cid:1)

G. Kaatz, S. Gibbons, S. M. Seo, 2007 .

Effect of Promoter Region Mutations and mgrA Overexpression on Transcription of norA, Which Encodes a Staphylococcus aureus Multidrug Efflux Transporter

G. Kaatz, S. M. Seo, R. Thyagarajan, 2005, Antimicrobial Agents and Chemotherapy.

Transport Protein Multidrug and Toxin Extrusion ( MATE ) Due to Overexpression of a Novel aureus Staphylococcus Multidrug Resistance in

G. Kaatz, S. M. Seo, F. McAleese, 2005 .

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction.

K. Kieć‐Kononowicz, G. Kaatz, D. Pietrella, 2018, Journal of medicinal chemistry.

MepR, a Repressor of the Staphylococcus aureus MATE Family Multidrug Efflux Pump MepA, Is a Substrate-Responsive Regulatory Protein

G. Kaatz, S. M. Seo, Carmen Demarco, 2006, Antimicrobial Agents and Chemotherapy.

Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides.

G. Kaatz, S. Gibbons, N. Jacobo-Herrera, 2008, Journal of natural products.

Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus.

G. Kaatz, S. Gibbons, R. Pereda-Miranda, 2006, Journal of natural products.

Comparison of a Rabbit Model of Bacterial Endocarditis and an In Vitro Infection Model with Simulated Endocardial Vegetations

G. Kaatz, M. Zervos, Elizabeth A. Coyle, 2000, Antimicrobial Agents and Chemotherapy.

CI-960, a new fluoroquinolone, for therapy of experimental ciprofloxacin-susceptible and -resistant Staphylococcus aureus endocarditis

G. Kaatz, E. Bailey, S. M. Seo, 1992, Antimicrobial Agents and Chemotherapy.

Efficacy ofOfloxacin inExperimental Staphylococcus aureus Endocarditis

G. Kaatz, 1990 .

Modulation of the drug resistance by Platonia insignis Mart. extract, ethyl acetate fraction and Morelloflavone/Volkensiflavone (biflavonoids) in Staphylococcus aureus strains overexpressing efflux pump genes.

G. Kaatz, Antonielly Campinho dos Reis, H. M. Barreto, 2020, Current drug metabolism.

Activities of Newer Fluoroquinolones against Ciprofloxacin-Resistant Streptococcus pneumoniae

G. Kaatz, M. Rybak, Elizabeth A. Coyle, 2001, Antimicrobial Agents and Chemotherapy.

Daptomycin compared with teicoplanin and vancomycin for therapy of experimental Staphylococcus aureus endocarditis

G. Kaatz, E. Bailey, S. M. Seo, 1990, Antimicrobial Agents and Chemotherapy.

In vitro activities of mutant prevention concentration-targeted concentrations of fluoroquinolones against Staphylococcus aureus in a pharmacodynamic model.

G. Kaatz, M. Rybak, G. Allen, 2004, International journal of antimicrobial agents.

Mutations within the mepA Operator Affect Binding of the MepR Regulatory Protein and Its Induction by MepA Substrates in Staphylococcus aureus

R. Brennan, G. Kaatz, B. Schindler, 2015, Journal of bacteriology.

Functional Consequences of Substitution Mutations in MepR, a Repressor of the Staphylococcus aureus mepA Multidrug Efflux Pump Gene

R. Brennan, M. Kumaraswami, G. Kaatz, 2013, Journal of bacteriology.

Effect of substrate exposure and other growth condition manipulations on norA expression.

G. Kaatz, S. M. Seo, 2004, The Journal of antimicrobial chemotherapy.

Enhanced elimination of ciprofloxacin after multiple-dose administration of rifampin to rabbits

G. Kaatz, S. M. Seo, S. Barriere, 1989, Antimicrobial Agents and Chemotherapy.

Topoisomerase Mutations in Fluoroquinolone-Resistant and Methicillin-Susceptible and -Resistant Clinical Isolates of Staphylococcus aureus

G. Kaatz, S. M. Seo, 1998, Antimicrobial Agents and Chemotherapy.

WIN 57273, a new fluoroquinolone with enhanced in vitro activity versus gram-positive pathogens

G. Kaatz, S. M. Seo, 1990, Antimicrobial Agents and Chemotherapy.

WIN 57273, a NewFluoroquinolone withEnhanced InVitro Activity versusGram-Positive Pathogens