Motoko Takahashi

发表

Role of N-glycans in growth factor signaling

Y. Ikeda, N. Taniguchi, Motoko Takahashi, 2003, Glycoconjugate Journal.

Elevation of aldose reductase gene expression in rat primary hepatoma and hepatoma cell lines: Implication in detoxification of cytotoxic aldehydes

N. Taniguchi, Motoko Takahashi, Junichi Funjii, 1995, International journal of cancer.

Identification of the Binding Site of Methylglyoxal on Glutathione Peroxidase: Methylglyoxal Inhibits Glutathione Peroxidase Activity via Binding to Glutathione Binding Sites Arg 184 and 185

Keiichiro Suzuki, Y. Park, N. Taniguchi, 2003, Free radical research.

Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.

Naoyuki Taniguchi, Yoshitaka Ikeda, Koichi Honke, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Pulmonary Surfactant Protein A Protects Lung Epithelium from Cytotoxicity of Human β-Defensin 3*

Motoko Takahashi, C. Nishitani, Y. Kuroki, 2012, The Journal of Biological Chemistry.

Functional roles of N‐glycans in cell signaling and cell adhesion in cancer

Naoyuki Taniguchi, Eiji Miyoshi, Akio Matsumoto, 2008, Cancer science.

A Circadian Clock Gene, Rev-erbα, Modulates the Inflammatory Function of Macrophages through the Negative Regulation of Ccl2 Expression

T. Kizaki, N. Taniguchi, K. Imaizumi, 2014, The Journal of Immunology.

A Circadian Clock Gene, Rev-erbα, Modulates the Inflammatory Function of Macrophages through the Negative Regulation of Ccl2 Expression

T. Kizaki, N. Taniguchi, K. Imaizumi, 2014, The Journal of Immunology.

Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes.

T. Kizaki, Motoko Takahashi, T. Sakurai, 2007, Journal of biochemistry.

This information is current as to Protect the Bladder from Infection Escherichia coli Adherence of Uropathogenic Surfactant Protein A Inhibits Growth and

Motoko Takahashi, R. Takamiya, N. Masumori, 2017 .

Surfactant Protein D Inhibits Adherence of Uropathogenic Escherichia coli to the Bladder Epithelial Cells and the Bacterium-induced Cytotoxicity

Motoko Takahashi, C. Nishitani, Y. Kuroki, 2012, The Journal of Biological Chemistry.

In vivo role of aldehyde reductase.

T. Soga, N. Taniguchi, J. Fujii, 2012, Biochimica et biophysica acta.

Functional glycomics and evidence for gain- and loss-of-functions of target proteins for glycosyltransferases involved in N-glycan biosynthesis: their pivotal roles in growth and development, cancer metastasis and antibody therapy against cancer

J. Gu, N. Taniguchi, Motoko Takahashi, 2004, Proceedings of the Japan Academy. Series B, Physical and Biological Sciences.

Glycosyltransferase Genes: Applications to Medical Science

Y. Ikeda, N. Taniguchi, Wenge Wang, 2000 .

Maillard reaction in vivo and its relevance to diseases: editorial and dedication

N. Taniguchi, Motoko Takahashi, 2021, Glycoconjugate Journal.

The internalization and metabolism of 3-deoxyglucosone in human umbilical vein endothelial cells.

N. Taniguchi, Motoko Takahashi, Y. Miyamoto, 2006, Journal of biochemistry.

Comparison of immune response in mice sensitized to an animal allergen, Can f 1, and to a food allergen, ovalbumin.

Motoko Takahashi, K. Yoshimatsu, J. Arikawa, 2019, Biomedical research.

Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury.

T. Homma, Jaeyong Lee, J. Fujii, 2018, Toxicology letters.

Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease

Motoko Takahashi, H. Chiba, Hiroki Takahashi, 2019, Respiratory Research.

The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.

Motoko Takahashi, R. Takamiya, Y. Kuroki, 2014, Biochemical and biophysical research communications.

Overexpression of N-Acetylglucosaminyltransferase III Enhances the Epidermal Growth Factor-induced Phosphorylation of ERK in HeLaS3 Cells by Up-regulation of the Internalization Rate of the Receptors*

N. Taniguchi, Motoko Takahashi, K. Honke, 2001, The Journal of Biological Chemistry.

Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress.

Motoko Takahashi, S. Ariki, A. Saito, 2021, Biochemistry.

Introduction of bisecting GlcNAc in N-glycans of adenylyl cyclase III enhances its activity.

J. Gu, Y. Ikeda, N. Taniguchi, 2007, Glycobiology.

Disease-associated glycans on cell surface proteins.

K. Ohtsubo, J. Gu, N. Taniguchi, 2016, Molecular aspects of medicine.

Down-regulation of Hydrogen Peroxide-induced PKCδ Activation in N-Acetylglucosaminyltransferase III-transfected HeLaS3 Cells*

N. Taniguchi, Motoko Takahashi, K. Honke, 2003, The Journal of Biological Chemistry.

A secreted type of beta1,6 N-acetylglucosaminyltransferase V (GnT-V), a novel angiogenesis inducer, is regulated by gamma-secretase.

J. Gu, M. Tohyama, S. Nakahara, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A secreted type of β1,6 N‐acetylglucosaminyltransferase V (GnT‐V), a novel angiogenesis inducer, is regulated by γ‐secretase

J. Gu, M. Tohyama, S. Nakahara, 2006 .

Spontaneous skin damage and delayed wound healing in SOD1-deficient mice

S. Kondo, J. Fujii, Motoko Takahashi, 2010, Molecular and Cellular Biochemistry.

Acrolein Induces Cyclooxygenase-2 and Prostaglandin Production in Human Umbilical Vein Endothelial Cells: Roles of p38 MAP Kinase

Jayoung Kim, M. Freeman, N. Taniguchi, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Identification and Evaluation of Potentially Genotoxic Agricultural and Food-related Chemicals

M. Honma, M. Hayashi, Motoko Takahashi, 2013 .

Glycation proceeds faster in mutated Cu, Zn‐superoxide dismutases related to familial amyotrophic lateral sclerosis

N. Taniguchi, J. Fujii, Motoko Takahashi, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ccl 2 Regulation of Macrophages through the Negative Modulates the Inflammatory Function of , α A Circadian Clock Gene

T. Kizaki, N. Taniguchi, K. Imaizumi, 2013 .

Surfactant protein A (SP-A) and SP-A-derived peptide attenuate chemotaxis of mast cells induced by human β-defensin 3.

Motoko Takahashi, R. Takamiya, Y. Kuroki, 2017, Biochemical and biophysical research communications.

Pulmonary Collectins Play Distinct Roles in Host Defense against Mycobacterium avium

Motoko Takahashi, Takeyuki Shimizu, C. Nishitani, 2011, The Journal of Immunology.

Mycobacterium avium Host Defense against Pulmonary Collectins Play Distinct Roles in

Motoko Takahashi, Takeyuki Shimizu, C. Nishitani, 2011 .

Pulmonary Collectins Protect Macrophages against Pore-forming Activity of Legionella pneumophila and Suppress Its Intracellular Growth*

Motoko Takahashi, Takeyuki Shimizu, H. Mitsuzawa, 2010, The Journal of Biological Chemistry.

A secreted type of (cid:1) 1,6 N -acetylglucosaminyltransferase V (GnT-V), a novel angiogenesis inducer, is regulated by (cid:2) -secretase

T. Saito, J. Gu, M. Tohyama, 2006 .

Life-Style Related Disease and Aging

K. Ohtsubo, Kazuro Furukawa, N. Taniguchi, 2019, Glycoscience: Basic Science to Applications.

Acrolein in cigarette smoke attenuates the innate immune responses mediated by surfactant protein D.

Motoko Takahashi, R. Takamiya, M. Nakano, 2020, Biochimica et biophysica acta. General subjects.

Involvement of Glycation and Oxidative Stress in Diabetic Macroangiopathy

Keiichiro Suzuki, H. Kaneto, J. Fujii, 1996, Diabetes.

Mutational analysis of Cys(88) of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression.

Motoko Takahashi, Takeyuki Shimizu, H. Mitsuzawa, 2009, International immunology.

Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain.

Motoko Takahashi, Takeyuki Shimizu, H. Mitsuzawa, 2008, Biochemistry.

Colocalization of polyol-metabolizing enzymes and immunological detection of fructated proteins in the female reproductive system of the rat

J. Fujii, Motoko Takahashi, T. Kaneko, 2003, Histochemistry and Cell Biology.

Localization and physiological implication of polyol-metabolyzing enzymes in male and female reproductive systems of rat

J. Fujii, Motoko Takahashi, T. Kaneko, 2002 .

Mannose binding lectin and lung collectins interact with Toll-like receptor 4 and MD-2 by different mechanisms.

Motoko Takahashi, Takeyuki Shimizu, H. Mitsuzawa, 2009, Biochimica et biophysica acta.

Introduction of Bisecting GlcNAc into Integrin α5β1 Reduces Ligand Binding and Down-regulates Cell Adhesion and Cell Migration*

K. Sekiguchi, J. Gu, T. Isaji, 2004, Journal of Biological Chemistry.

Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration.

K. Sekiguchi, J. Gu, T. Isaji, 2004, The Journal of biological chemistry.

Core fucosylation of E‐cadherin enhances cell–cell adhesion in human colon carcinoma WiDr cells

J. Gu, D. Osumi, Y. Ikeda, 2009, Cancer science.

Localization and physiological implication of aldose reductase and sorbitol dehydrogenase in reproductive tracts and spermatozoa of male rats.

J. Fujii, Motoko Takahashi, T. Nakada, 2002, Journal of andrology.

Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins.

K. Ohtsubo, N. Taniguchi, Motoko Takahashi, 2009, Carbohydrate research.

Beta1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells.

J. Gu, T. Isaji, Y. Ikeda, 2003, Glycobiology.

Suppression of Heregulin β Signaling by the Single N-Glycan Deletion Mutant of Soluble ErbB3 Protein*

M. Tajiri, Y. Wada, Y. Ikeda, 2013, The Journal of Biological Chemistry.

Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells.

Keiichiro Suzuki, N. Taniguchi, Y. Koh, 2005, Biochemical and biophysical research communications.

Induction of Aldose Reductase Gene Expression in LEC Rats during the Development of the Hereditary Hepatitis and Hepatoma

Keiichiro Suzuki, K. Aozasa, N. Taniguchi, 1996, Japanese journal of cancer research : Gann.

Pulmonary collectins in innate immunity of the lung

Motoko Takahashi, C. Nishitani, Y. Kuroki, 2007, Cellular microbiology.

N-glycans of growth factor receptors: their role in receptor function and disease implications.

N. Taniguchi, Motoko Takahashi, Y. Kuroki, 2016, Clinical science.

A glycomic approach to the identification and characterization of glycoprotein function in cells transfected with glycosyltransferase genes

Y. Ikeda, J. Ko, Motoko Takahashi, 2001, Proteomics.

Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factor-binding protein 3 in Fut8-/- mice.

Naoyuki Taniguchi, Koichi Honke, Eiji Miyoshi, 2006, Journal of biochemistry.

Treatment of air leakage using the VIO soft coagulation system: a mouse pulmonary air leak model

Motoko Takahashi, A. Watanabe, Y. Sakuma, 2021, Surgery Today.

Role of glycosyltransferases in carcinogenesis; growth factor signaling and EMT/MET programs

Motoko Takahashi, Y. Hasegawa, Kento Maeda, 2022, Glycoconjugate Journal.

Glycation in Disease

Keiichiro Suzuki, Y. Ikeda, N. Taniguchi, 2020 .

Glycation of Proteins

Motoko Takahashi, Motoko Takahashi, 2019, Co and Post-Translational Modifications of Therapeutic Antibodies and Proteins.

4.28 – Glycation and Disease

Y. Ikeda, N. Taniguchi, Motoko Takahashi, 2007 .

Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke

Y. Yamaguchi, Motoko Takahashi, R. Takamiya, 2017, Scientific Reports.

Glycation vs. glycosylation: a tale of two different chemistries and biology in Alzheimer’s disease

N. Taniguchi, Yasuhiko Kizuka, S. Kitazume, 2016, Glycoconjugate Journal.

Aldehyde reductase gene expression by lipid peroxidation end products, MDA and HNE

Keiichiro Suzuki, M. Takahashi, N. Taniguchi, 2000, Free radical research.

A Common Pathway for Intracellular Reactive Oxygen Species Production by Glycoxidative and Nitroxidative Stress in Vascular Endothelial Cells and Smooth Muscle Cells

N. Taniguchi, Motoko Takahashi, Y. Miyamoto, 2005, Annals of the New York Academy of Sciences.

Acrolein induces Hsp72 via both PKCδ/JNK and calcium signaling pathways in human umbilical vein endothelial cells

N. Taniguchi, Motoko Takahashi, Y. Miyamoto, 2005, Free radical research.

Pleiotropic Actions of Aldehyde Reductase (AKR1A)

T. Homma, J. Fujii, Motoko Takahashi, 2021, Metabolites.

The Effects of Exercise Training on Obesity-Induced Dysregulated Expression of Adipokines in White Adipose Tissue

T. Kizaki, Motoko Takahashi, T. Sakurai, 2013, International journal of endocrinology.

Surfactant protein A down-regulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D

Motoko Takahashi, R. Takamiya, Y. Kuroki, 2017, The Journal of Biological Chemistry.

Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner.

G. Siest, N. Taniguchi, Motoko Takahashi, 2002, Biochemical and biophysical research communications.

Pulmonary Surfactant Protein D Inhibits Lipopolysaccharide (LPS)-induced Inflammatory Cell Responses by Altering LPS Binding to Its Receptors*

Motoko Takahashi, D. Voelker, Takeyuki Shimizu, 2008, Journal of Biological Chemistry.

Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis

Motoko Takahashi, H. Chiba, Hiroki Takahashi, 2018, Respiratory Research.

The Asn418-linked N-glycan of ErbB3 plays a crucial role in preventing spontaneous heterodimerization and tumor promotion.

D. Osumi, N. Taniguchi, Motoko Takahashi, 2007, Cancer research.

Promotion in Preventing Spontaneous Heterodimerization and Tumor-Glycan of ErbB 3 Plays a Crucial Role N-Linked 418 The Asn

D. Osumi, N. Taniguchi, Motoko Takahashi, 2007 .

Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease.

N. Taniguchi, Yasuhiko Kizuka, S. Kitazume, 2015, Journal of proteomics.

Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.

T. Homma, Jaeyong Lee, T. Kurahashi, 2014, Biochemical and biophysical research communications.

Selective Induction of Heparin-binding Epidermal Growth Factor-like Growth Factor by Methylglyoxal and 3-Deoxyglucosone in Rat Aortic Smooth Muscle Cells

H. Kaneto, N. Taniguchi, W. Che, 1997, The Journal of Biological Chemistry.

Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.

Junitsu Ito, N. Otsuki, T. Kurahashi, 2014, Life sciences.

Detection of N‐glycolyated gangliosides in non‐small‐cell lung cancer using GMR8 monoclonal antibody

Motoko Takahashi, T. Hasegawa, Y. Kuroki, 2013, Cancer science.

Surfactant Protein A Inhibits Growth and Adherence of Uropathogenic Escherichia coli To Protect the Bladder from Infection

Motoko Takahashi, R. Takamiya, N. Masumori, 2017, The Journal of Immunology.

Glycosyltransferases: cell surface remodeling and regulation of receptor tyrosine kinases-induced signaling

Y. Ikeda, N. Taniguchi, J. Ko, 1999 .

CINC-2 and miR-199a-5p in EVs secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration

T. Ochiya, Motoko Takahashi, Y. Yoshioka, 2023, Stem Cell Research & Therapy.

Overexpression of mutated Cu,Zn-SOD in neuroblastoma cells results in cytoskeletal change.

Keiichiro Suzuki, J. Gu, N. Taniguchi, 2005, American journal of physiology. Cell physiology.

Results in Cytoskeletal Change

Keiichiro Suzuki, J. Gu, N. Taniguchi, 2004 .

Amadoriase Isoenzymes (Fructosyl Amine: Oxygen Oxidoreductase EC 1.5.3) from Aspergillus Fumigatus

V. Monnier, Motoko Takahashi, M. Pischetsrieder, 2005 .

Junctional adhesion molecule 3 is a potential therapeutic target for small cell lung carcinoma.

M. Yamaguchi, M. Idogawa, Motoko Takahashi, 2023, Experimental cell research.

N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.

D. Osumi, N. Taniguchi, Motoko Takahashi, 2008, Biochimica et biophysica acta.

Measurement of peroxiredoxin-4 serum levels in rat tissue and its use as a potential marker for hepatic disease.

Y. Ikeda, J. Fujii, Motoko Takahashi, 2012, Molecular medicine reports.

Different Immunoreactivity against Monoclonal Antibodies between Wild-type and Mutant Copper/Zinc Superoxide Dismutase Linked to Amyotrophic Lateral Sclerosis*

Keiichiro Suzuki, T. Ikegami, N. Taniguchi, 2005, Journal of Biological Chemistry.

This information is current as Mycobacterium avium Host Defense against Pulmonary Collectins Play Distinct Roles in

Motoko Takahashi, Takeyuki Shimizu, C. Nishitani, 2011 .

Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines.

M. Takahashi, N. Taniguchi, J. Fujii, 1996, Biochemical and biophysical research communications.

Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction

Motoko Takahashi, A. Yoneda, A. Takasawa, 2019, Scientific Reports.

Measurement of peroxiredoxin-4 serum levels in rat tissue and its use as a potential marker for hepatic disease.

Y. Ikeda, J. Fujii, Motoko Takahashi, 2012, Molecular medicine reports.

N‐glycosylation regulates MET processing and signaling

Motoko Takahashi, Kunio Matsumoto, H. Chiba, 2022, Cancer science.

Expression Ccl2 Regulation of Macrophages through the Negative Modulates the Inflammatory Function of , a A Circadian Clock Gene, Rev-erb

T. Kizaki, N. Taniguchi, K. Imaizumi, 2013 .

Fragmentation of ceruloplasmin following non-enzymatic glycation reaction.

Motoko Takahashi, S. Higashiyama, M. Takahashi, 1995, Journal of biochemistry.