B. Helm

发表

Protein mapping in rat basophilic leukaemia cells.

K. Carroll, E. Carey, B. Helm, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Two‐dimensional electrophoresis reveals differential protein expression in high‐ and low‐secreting variants of the rat basophilic leukaemia cell line

K. Carroll, E. Carey, B. Helm, 2000, Electrophoresis.

The nature and importance of the inter‐ε chain disulfide bonds in human IgE

E. Padlan, M. Brüggemann, Y. Ling, 1991, European journal of immunology.

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcɛRI.

B. Helm, Sari Sabban, Hongtu Ye, 2013, Veterinary immunology and immunopathology.

Proteomic identification and characterization of secreted N‐glycosylated NPC2 following cross‐linking of the high‐affinity receptor for IgE on mast cells

B. Helm, A. Pathak, 2010, Cell biology international.

Inhibition of the Prausnitz–Küstner reaction by an immunoglobulin ε-chain fragment synthesized in E. coli

R. Geha, B. Helm, H. Gould, 1985, Nature.

Differential expression of Rab3 isoforms in high- and low-secreting mast cell lines.

K. Carroll, E. Carey, B. Helm, 2001, European journal of cell biology.

Human IgE mediates stimulus secretion coupling in rat basophilic leukemia cells transfected with the α chain of the human high‐affinity receptor

B. Helm, C. Pullar, A. Wilson, 1993 .

The effect of insulinomimetic agents on protein degradation in H35 hepatoma cells

B. Helm, J. Martyn Gunn, 1986, Molecular and Cellular Biochemistry.

Protein and cell engineering of components of the human immunoglobulin E receptor/effector system: applications for therapy and diagnosis.

I. Sayers, E. Padlan, B. Helm, 1998, Technology and health care : official journal of the European Society for Engineering and Medicine.

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI.

B. Helm, Sari Sabban, Hongtu Ye, 2014, Journal of visualized experiments : JoVE.

Blocking of passive sensitization of human mast cells and basophil granulocytes with IgE antibodies by a recombinant human epsilon-chain fragment of 76 amino acids.

R. Geha, B. Helm, D. Vercelli, 1989, Proceedings of the National Academy of Sciences of the United States of America.

A monoclonal anti-IgE antibody against an epitope (amino acids 367-376) in the CH3 domain inhibits IgE binding to the low affinity IgE receptor (CD23).

J. Banchereau, E. Padlan, B. Helm, 1988, Journal of immunology.

The mast cell binding site on human immunoglobulin E

E. Padlan, R. Geha, B. Helm, 1988, Nature.

A proteomics approach to the study of the molecular consequence of IgE‐mediated cell signalling in RBL‐2H3.1 cells and 2D reference map preparation for the RBL‐2H3.1 cell line

A. Moir, B. Helm, E. Sadroddiny, 2012, Cell biology international.

Identification of the High Affinity Receptor Binding Region in Human Immunoglobulin E (*)

E. Padlan, A. Higginbottom, Y. Ling, 1996, The Journal of Biological Chemistry.

Peptide blocking of IgE/receptor interaction: possibilities and pitfalls

E. Padlan, B. Helm, A. Spivey, 1997, Allergy.

Modelling study of IgE/receptor interactions.

E. Padlan, B. Helm, 1993, Biochemical Society transactions.

A modeling study of the alpha-subunit of human high-affinity receptor for immunoglobulin-E.

E. Padlan, B. Helm, 1995, Receptor.

Biological properties of a recombinant human immunoglobulin epsilon-chain fragment.

B. Helm, K. Ishizaka, H. Gould, 1986, Proceedings of the National Academy of Sciences of the United States of America.

The role of Cε2, Cε3, and Cε4 domains in human and canine IgE and their contribution to FcεRIα interaction.

B. Helm, J. Housden, Sari Sabban, 2014, Molecular immunology.

Review: Diagnostic and therapeutic applications of rat basophilic leukemia cells.

B. Helm, Amir Rashid, E. Sadroddiny, 2012, Molecular immunology.

Inhibition of the Prausnitz-Küstner reaction by an immunoglobulin epsilon-chain fragment synthesized in E. coli.

R. Geha, B. Helm, H. Gould, 1985, Nature.

Synthesis and incorporation into cyclic peptides of tolan amino acids and their hydrogenated congeners: construction of an array of A-B-loop mimetics of the Cε3 domain of human IgE.

A. Beavil, B. Sutton, B. Helm, 2012, The Journal of organic chemistry.

Solid-phase synthesis of an A-B loop mimetic of the Cepsilon3 domain of human IgE: macrocyclization by Sonogashira coupling.

B. Helm, A. Spivey, J. Mckendrick, 2003, The Journal of organic chemistry.

Identification of amino acid residues involved in the interaction of canine IgE with canine and human FcεRIα.

B. Helm, J. Housden, Sari Sabban, 2014, Molecular immunology.

Generation of canine-human Fc IgE chimeric antibodies for the determination of the canine IgE domain of interaction with Fc epsilon RI alpha.

B. Helm, J. Housden, A. Vratimos, 2008, Molecular immunology.

Observations on the nature and the interaction of a carotenoprotein and a cytochrome from the eggs of a prosobranch mollusc

B. Helm, 1980 .

Properties of a human immunoglobulin epsilon-chain fragment synthesized in Escherichia coli.

J. Kenten, P. Cattini, B. Helm, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Assessing the role of Asp 194 in the transmembrane domains of the α-chain of the high-affinity receptor complex for immunoglobulin E in signal transduction.

P. Artymiuk, K. Carroll, B. Helm, 2010, Molecular immunology.

Potential allergens stimulate the release of mediators of the allergic response from cells of mast cell lineage in the absence of sensitization with antigen‐specific IgE

B. Helm, D. Machado, P. Peachell, 1996, European journal of immunology.

Structure/function studies on IgE as a basis for the development of rational IgE

E. Padlan, B. Helm, A. Spivey, 1998 .

Protein profiling of the secretome of FcεRI activated RBL-2H3.1 cells.

P. Wright, T. K. Pham, B. Helm, 2012, Iranian journal of immunology : IJI.

Is there a link between the nature of agents that trigger mast cells and the induction of immunoglobulin (Ig)E synthesis?

B. Helm, 1994, Advances in experimental medicine and biology.

The Importance of Lys-352 of Human Immunoglobulin E in FcϵRII/CD23 Recognition*

Alan C. Spivey, Ian Sayers, I. Sayers, 2004, Journal of Biological Chemistry.

Inhibition of mast cell sensitization in vitro by a human immunoglobulin ϵ‐chain fragment synthesized in Escherichia coli

B. Helm, H. Gould, D. Stanworth, 1985 .

The isoelectric points of cytochromes in the reduced and oxidised forms.

B. Helm, 1982, Comparative biochemistry and physiology. B, Comparative biochemistry.

Assessment of the molecular basis of the proallergenic effects of cigarette smoke

B. Helm, D. Machado, M. Aufderheide, 2000 .

A link between catalytic activity, IgE-independent mast cell activation, and allergenicity of bee venom phospholipase A2.

M. Gelb, B. Helm, D. Machado, 1995, Journal of immunology.

Defective protein phosphorylation and Ca2+ mobilization in a low secreting variant of the rat basophilic leukemia cell line.

P. Monk, B. Helm, B. Bingham, 1994, The Journal of biological chemistry.

Characterization of an early signaling defect following Fc epsilonRI activation in the canine mastocytoma cell line, C2.

B. Helm, A. Pathak, M. Street, 2009, Molecular Immunology.

Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).

E. Padlan, B. Helm, 1993, Receptor.

Towards a Pan-Anti-Allergy Vaccine

A. Moir, B. Helm, A. Vratimos, 2013 .

Amino acid residues that influence Fc epsilon RI-mediated effector functions of human immunoglobulin E.

I. Sayers, E. Padlan, S. Holgate, 1998, Biochemistry.

Characterization of an early signaling defect following Fc epsilonRI activation in the canine mastocytoma cell line, C2.

B. Helm, M. Street, M. Hunter, 2009, Molecular Immunology.

Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells.

B. Helm, Amir Rashid, J. Housden, 2013, Molecular immunology.

Report-Model studies of transmembrane interaction of FcεRIα/FcRγ reveal novel strategies to inhibit allergic responses.

B. Helm, Amir Rashid, A. Majeed, 2018, Pakistan journal of pharmaceutical sciences.

High affinity IgE-Fc receptor α and γ subunit interactions.

B. Helm, Amir Rashid, J. Housden, 2014, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.