D. Thakker

发表

Orphanin FQ/Nociceptin-Mediated Desensitization of Opioid Receptor-Like 1 Receptor and μ Opioid Receptors Involves Protein Kinase C: A Molecular Mechanism for Heterologous Cross-Talk

C. Mandyam, D. Thakker, J. Christensen, 2002, Journal of Pharmacology and Experimental Therapeutics.

Cellular Mechanisms of Nociceptin/Orphanin FQ (N/OFQ) Peptide (NOP) Receptor Regulation and Heterologous Regulation by N/OFQ

D. Thakker, K. Standifer, Courtney L. Donica, 2013, Molecular Pharmacology.

Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between μ and ORL1 receptors following prolonged agonist exposure

D. Thakker, K. Standifer, 2002, Neuropharmacology.

Assessing opioid regulation of adenylyl cyclase activity in intact cells.

D. Thakker, K. Standifer, H. Ozsoy, 2003, Methods in molecular medicine.

Mu opioid-induced desensitization of ORL 1 and mu opioid receptors : Differential intracellular signaling determines receptor sensitivity

C. Mandyam, D. Thakker, K. Standifer, 2003 .

Differential intracellular signaling determines receptor sensitivity

C. Mandyam, D. Thakker, K. Standifer, 2003 .

Interfering with the brain: use of RNA interference for understanding the pathophysiology of psychiatric and neurological disorders.

D. Hoyer, J. Cryan, D. Thakker, 2006, Pharmacology & therapeutics.

mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity

M. Fendt, P. Kelly, F. Natt, 2008, Molecular Psychiatry.

Global Down-Regulation of Gene Expression in the Brain Using RNA Interference, with Emphasis on Monoamine Transporters and GPCRs: Implications for Target Characterization in Psychiatric and Neurological Disorders

Dieter Huesken, F. Natt, D. Hoyer, 2006, Journal of receptor and signal transduction research.

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference.

F. Natt, D. Hoyer, J. Cryan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse

D. Hoyer, J. Cryan, D. Thakker, 2013, Neuropharmacology.

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005, Molecular Psychiatry.

Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice

D. Thakker, C. Albright, S. Sankaranarayanan, 2015, Journal of Neuroscience.

Orphanin FQ/nociceptin blocks chronic morphine-induced tyrosine hydroxylase upregulation.

D. Thakker, K. Standifer, 2002, Brain research. Molecular brain research.

Widespread brain distribution and activity following i.c.v. infusion of anti‐β‐secretase (BACE1) in nonhuman primates

K. Scearce-Levie, K. Gadkar, A. Daugherty, 2017, British journal of pharmacology.

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005, Molecular Psychiatry.

μ-Opioid-Induced Desensitization of Opioid Receptor-Like 1 and μ-Opioid Receptors: Differential Intracellular Signaling Determines Receptor Sensitivity

C. Mandyam, D. Thakker, K. Standifer, 2003, Journal of Pharmacology and Experimental Therapeutics.

Orphanin FQ/Nociceptin Potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-Enkephalin–Induced μ-Opioid Receptor Phosphorylation

D. Thakker, K. Standifer, H. Ozsoy, 2005, Molecular Pharmacology.

Emerging use of non-viral RNA interference in the brain.

D. Hoyer, J. Cryan, D. Thakker, 2007, Biochemical Society transactions.

Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum

P. Nelson, D. Thakker, Zhiming Zhang, 2012, Brain : a journal of neurology.

(cid:1) -Opioid-Induced Desensitization of Opioid Receptor-Like 1 and (cid:1) -Opioid Receptors: Differential Intracellular Signaling Determines Receptor Sensitivity

C. Mandyam, D. Thakker, K. Standifer, 2003 .

Intracerebroventricular amyloid-β antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

D. Thakker, W. Kaemmerer, Marcy R Weatherspoon, 2009, Proceedings of the National Academy of Sciences.

Naloxone benzoylhydrazone activates Extracellular Signal-Regulated Protein Kinases and modulates Nociceptin Opioid Peptide Receptor activity

C. Mandyam, D. Thakker, K. Standifer, 2007 .

Orphanin FQ/Nociceptin Potentiates [ D -Ala 2 , N -Me-Phe 4 ,Gly 5 -ol]-Enkephalin–Induced (cid:1) -Opioid Receptor Phosphorylation

D. Thakker, K. Standifer, H. Ozsoy, 2005 .

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005 .

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, J. Cryan, D. Thakker, 2005, Molecular Psychiatry.