J. Lambeth

发表

Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system.

M. Dinauer, U. Knaus, Marianne O. Price, 2002, Blood.

Novel gp91phox Homologues in Vascular Smooth Muscle Cells: nox1 Mediates Angiotensin II-Induced Superoxide Formation and Redox-Sensitive Signaling Pathways

D. Sorescu, M. Akers, Q. Yin, 2001, Circulation research.

Cell transformation by the superoxide-generating oxidase Mox1

Y. Suh, D. Sorescu, K. Griendling, 1999, Nature.

Point Mutations in the Proline-rich Region of p22phox Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation*

T. Kawahara, J. Lambeth, D. Ritsick, 2005, Journal of Biological Chemistry.

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4*

A. Shah, R. Brandes, J. Lambeth, 2011, The Journal of Biological Chemistry.

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox

J. Lambeth, Taehoon G. Lee, D. Flaherty, 2001, The Journal of cell biology.

Novel homologs of gp91phox.

J. Lambeth, R. Arnold, G. Cheng, 2000, Trends in biochemical sciences.

Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis

W. R. Taylor, Mark T. Quinn, D. Weiss, 2002, Circulation.

NOX enzymes and the biology of reactive oxygen

J. Lambeth, 2004, Nature Reviews Immunology.

Cytochrome P-450scc a review of the specificity and properties of the cholesterol binding site.

J. Lambeth, 1986, Endocrine research.

Use of cytochrome P-450scc to measure cholesterol-lipid interactions.

V. Stevens, A. Merrill, J. Lambeth, 1986, Biochemistry.

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair.

C. Reutelingsperger, G. Leoni, M. Perretti, 2013, The Journal of clinical investigation.

Rac “Insert Region” Is a Novel Effector Region That Is Implicated in the Activation of NADPH Oxidase, but Not PAK65*

A. Abo, J. Lambeth, J. Freeman, 1996, The Journal of Biological Chemistry.

Adrenodoxin reductase. Properties of the complexes of reduced enzyme with NADP+ and NADPH.

J. Lambeth, H. Kamin, 1976, The Journal of biological chemistry.

Adrenodoxin reductase-adrenodexin complex.

J. Lambeth, D. McCaslin, H. Kamin, 1976, The Journal of biological chemistry.

Adrenodoxin reductase and adrenodoxin. Mechanisms of reduction of ferricyanide and cytochrome c.

J. Lambeth, H. Kamin, 1977, The Journal of biological chemistry.

Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle.

J. Lambeth, H. Kamin, D. Seybert, 1979, The Journal of biological chemistry.

Adrenodoxin reductase.adrenodoxin complex. Flavin to iron-sulfur electron transfer as the rate-limiting step in the NADPH-cytochrome c reductase reaction.

J. Lambeth, H. Kamin, 1979, The Journal of biological chemistry.

Adrenodoxin reductase . adrenodoxin complex. Rapid formation and breakdown of the complex and a slow conformational change in the flavoprotein.

J. Lambeth, H. Kamin, D. Seybert, 1980, The Journal of biological chemistry.

Steroidogenic electron transport in adrenal cortex mitochondria

J. Lancaster, J. Lambeth, H. Kamin, 1982, Molecular and Cellular Biochemistry.

On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation.

J. Lambeth, B. Kalyanaraman, J. Zielonka, 2013, Free radical biology & medicine.

Granulocyte/macrophage colony‐stimulating factor primes human neutrophils for increased diacylglycerol generation in response to chemoattractant

J. Lambeth, E. Winton, S. Tyagi, 1989, FEBS letters.

Steroidogenic electron transport by adrenodoxin reductase and adrenodoxin. Use of acetylated cytochrome c as a mechanistic probe of electron transfer.

J. Lancaster, J. Lambeth, H. Kamin, 1981, The Journal of biological chemistry.

Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.

D. Harrison, K. Griendling, J. Lambeth, 2010, American journal of physiology. Heart and circulatory physiology.

Identification and characterization of VPO1, a new animal heme-containing peroxidase.

J. Lambeth, G. Cheng, P. Pagano, 2008, Free radical biology & medicine.

Phosphatidylinositol ( 4 , 5 )-bisphosphate Modulates Nox 5 Localization via an N-Terminal Polybasic Region

T. Kawahara, J. Lambeth, 2008 .

Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited.

J. Lambeth, A. Neish, 2014, Annual review of pathology.

Regulation of Nox and Duox enzymatic activity and expression.

T. Kawahara, J. Lambeth, B. Diebold, 2007, Free radical biology & medicine.

Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3.

J. Lambeth, G. Cheng, 2005, Gene.

Nox3 Regulation by NOXO1, p47phox, and p67phox*

J. Lambeth, D. Ritsick, G. Cheng, 2004, Journal of Biological Chemistry.

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

J. Lambeth, 2002, Current opinion in hematology.

NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain*

J. Lambeth, G. Cheng, 2004, Journal of Biological Chemistry.

Nox1-dependent Reactive Oxygen Generation Is Regulated by Rac1*

J. Lambeth, B. Diebold, G. Cheng, 2006, Journal of Biological Chemistry.

Participation of the small molecular weight GTP-binding protein Rac1 in cell-free activation and assembly of the respiratory burst oxidase. Inhibition by a carboxyl-terminal Rac peptide.

J. Lambeth, K. Inge, S. Tyagi, 1994, The Journal of biological chemistry.

Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits.

J. Snyder, H. Fu, Jaeki Min, 2012, Chemistry & biology.

Ebselen Congeners Inhibit NADPH-oxidase 2 (Nox2)Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits

J. Snyder, H. Fu, Jaeki Min, 2011 .

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

W. D. Martin, Elizabeth R. Smith, Xiang-Xi Xu, 2002, Developmental biology.

Cell-free synthesis of precursor forms of mitochondrial steroid hydroxylase enzymes of the bovine adrenal cortex.

M. Waterman, C. Anderson, C. Jefcoate, 1982, Archives of biochemistry and biophysics.

Protein determination on the basis of copper-binding capacity.

J. Lambeth, J. Westley, 1960, Biochimica et biophysica acta.

Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase.

J. Lambeth, K. Kameda, M. Tamura, 2000, Biochemical and biophysical research communications.

The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H₂0₂ and plays an integral role in insulin signal transduction

H. Motoshima, J. Lambeth, B. Goldstein, 2022 .

NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice

W. Cao, P. Ranjan, Jazmina L G Cruz, 2016, PloS one.

High-throughput Assays for Superoxide and Hydrogen Peroxide

J. Lambeth, J. Joseph, B. Kalyanaraman, 2014, The Journal of Biological Chemistry.

Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells.

M. Waterman, R. DuBois, J. Lambeth, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Cytochrome P-450scc: enzymology, and the regulation of intramitochondrial cholesterol delivery to the enzyme.

V. Stevens, J. Lambeth, 1984, Endocrine research.

Cytochrome P-450scc-substrate interactions. Role of the 3 beta- and side chain hydroxyls in binding to oxidized and reduced forms of the enzyme.

J. Lambeth, D. Tyrrell, B. L. Heyl, 1986, The Journal of biological chemistry.

Chapter 2. Enzymology of Mitochondrial Side-Chain Cleavage by Cytochrome P-450scc

J. Lambeth, 1990, Molecular mechanisms of adrenal steroidogenesis and aspects of regulation and application.

Cytochrome P-450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols.

J. Lambeth, A. A. Farooqui, H. Kamin, 1982, The Journal of biological chemistry.

GTP stimulates pregnenolone generation in isolated rat adrenal mitochondria.

J. Lambeth, T. Xu, X. Xu, 1989, The Journal of biological chemistry.

Stimulation of adrenal mitochondrial cholesterol side-chain cleavage by GTP, steroidogenesis activator polypeptide (SAP), and sterol carrier protein2. GTP and SAP act synergistically.

J. Lambeth, T. Xu, D. Glass, 1991, The Journal of biological chemistry.

Cytochrome P-450scc. Cardiolipin as an effector of activity of a mitochondrial cytochrome P-450.

J. Lambeth, 1981, The Journal of biological chemistry.

Cytochrome P-450scc-adrenodoxin complex. Reduction properties of the substrate-associated cytochrome and relation of the reduction states of heme and iron-sulfur centers to association of the proteins.

J. Lambeth, S. Pember, 1983, The Journal of biological chemistry.

Phospholipid vesicle-reconstituted cytochrome P-450SCC. Mutually facilitated binding of cholesterol and adrenodoxin.

J. Lambeth, H. Kamin, D. Seybert, 1980, The Journal of biological chemistry.

Participation of the membrane in the side chain cleavage of cholesterol. Reconstitution of cytochrome P-450scc into phospholipid vesicles.

J. Lancaster, J. Lambeth, H. Kamin, 1979, The Journal of biological chemistry.

Cytochrome P-450scc-adrenodoxin interactions. Ionic effects on binding, and regulation of cytochrome reduction by bound steroid substrates.

J. Lambeth, S. Kriengsiri, 1985, The Journal of biological chemistry.

Cytochrome P-450scc-phospholipid interactions. Evidence for a cardiolipin binding site and thermodynamics of enzyme interactions with cardiolipin, cholesterol, and adrenodoxin.

J. Lambeth, G. Powell, S. Pember, 1983, The Journal of biological chemistry.

Redox signaling regulates commensal mediated mucosal homeostasis and restitution and requires formyl peptide receptor 1 (FPR1)

G. Leoni, J. Lambeth, A. Nusrat, 2013, Mucosal Immunology.

A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils.

S. Ryu, P. Suh, J. Lambeth, 1997, Journal of immunology.

Immunity Reactive Oxygen Species Promote IL-4 Signaling

M. Tremblay, S. Haque, T. Kawahara, 2008 .

Functional differences in human neutrophils isolated pre‐ and post‐prandially

C. Cutler, A. Merrill, R. Arnold, 1991, FEBS letters.

Insulin-stimulated hexose transport and glucose oxidation in rat adipocytes is inhibited by sphingosine at a step after insulin binding.

A. Merrill, J. Lambeth, M. Digirolamo, 1989, The Journal of biological chemistry.

Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells

K. Griendling, R. Clempus, J. Lambeth, 2004, Arteriosclerosis, thrombosis, and vascular biology.

The Superoxide-Generating Oxidase Nox1 Is Functionally Required for Ras Oncogene Transformation

J. Lambeth, J. Mitsushita, T. Kamata, 2004, Cancer Research.

Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

J. Lambeth, T. Liang, Jinah Choi, 2010, Hepatology.

Sterol carrier protein2. Identification of adrenal sterol carrier protein2 and site of action for mitochondrial cholesterol utilization.

R. Chanderbhan, J. Lambeth, T. Scallen, 1983, The Journal of biological chemistry.

Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

J. Lambeth, V. Thannickal, G. Cheng, 2012, Infection and Immunity.

Spring brings breezes, wheezes, and pollen oxidases.

J. Lambeth, D. Ritsick, 2005, The Journal of clinical investigation.

Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy.

J. Lambeth, 2007, Free radical biology & medicine.

Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival

W. Cao, P. Ranjan, J. Lambeth, 2021, PloS one.

The Nox Enzymes and the Regulated Generation of Reactive Oxygen Species

J. Lambeth, R. Arnold, 2003 .

Regulation of the Phagocyte Respiratory Burst Oxidase by Protein Interactions

J. Lambeth, 2000 .

The p67 phox Activation Domain Regulates Electron Flow from NADPH to Flavin in Flavocytochromeb 558 *

J. Lambeth, Chang-Hoon Han, Y. Nisimoto, 1999, The Journal of Biological Chemistry.

Regulation of the Neutrophil Respiratory Burst Oxidase

J. Lambeth, Chang-Hoon Han, J. Freeman, 1998, The Journal of Biological Chemistry.

NADPH Oxidase Activity Is Independent of p47phox in Vitro*

J. Lambeth, J. Freeman, Jennifer L. Freeman, 1996, The Journal of Biological Chemistry.

NADPH Oxidase Activity Is Independent of p47 in Vitro*

J. Lambeth, J. Freeman, 1996 .

Ras effector-homologue region on Rac regulates protein associations in the neutrophil respiratory burst oxidase complex.

J. Lambeth, J. Freeman, M. Kreck, 1994, Biochemistry.

Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts*

H. Forman, J. Lambeth, J. Hagood, 2010, The Journal of Biological Chemistry.

RhoA and a Cytosolic 50-kDa Factor Reconstitute GTPγS-dependent Phospholipase D Activity in Human Neutrophil Subcellular Fractions (*)

J. Kwak, S. Ryu, J. Lambeth, 1995, The Journal of Biological Chemistry.

The respiratory burst oxidase of human neutrophils. Guanine nucleotides and arachidonate regulate the assembly of a multicomponent complex in a semirecombinant cell-free system.

J. Lambeth, K. Inge, S. Tyagi, 1993, The Journal of biological chemistry.

Nucleoside triphosphate requirements for superoxide generation and phosphorylation in a cell-free system from human neutrophils. Sodium dodecyl sulfate and diacylglycerol activate independently of protein kinase C.

J. Lambeth, D. Uhlinger, D. Burnham, 1991, The Journal of biological chemistry.

Diradylglycerol synergizes with an anionic amphiphile to activate superoxide generation and phosphorylation of p47phox in a cell-free system from human neutrophils.

J. Lambeth, D. Uhlinger, D. Burnham, 1990, The Journal of biological chemistry.

Cholesterol trafficking in steroidogenic cells. Reversible cycloheximide-dependent accumulation of cholesterol in a pre-steroidogenic pool.

V. Stevens, J. Lambeth, T. Xu, 1993, European journal of biochemistry.

ADP-ribosylation Factor Functions Synergistically with a 50-kDa Cytosolic Factor in Cell-free Activation of Human Neutrophil Phospholipase D (*)

J. Kwak, J. Lambeth, E. Bowman, 1995, The Journal of Biological Chemistry.

Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils.

A. Merrill, R. Arnold, J. Lambeth, 1987, Archives of biochemistry and biophysics.

Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

A. Shah, Jian-Mei Li, J. Lambeth, 2003, Circulation research.

Lipase Activities of p37, the Major Envelope Protein of Vaccinia Virus*

J. Kwak, S. Ryu, J. Lambeth, 1997, The Journal of Biological Chemistry.

Generation of Hypochlorous Acid Peroxidase 1 in Human Plasma via Microbicidal Activity of Vascular

J. Lambeth, V. Thannickal, Zehong Cao, 2012 .

Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.

J. Lambeth, M. Tamura, S. Tyagi, 1988, The Journal of biological chemistry.

Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.

A. Merrill, D. Liotta, J. Lambeth, 1988, The Journal of biological chemistry.

Stabilization of the superoxide-generating respiratory burst oxidase of human neutrophil plasma membrane by crosslinking with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide.

J. Lambeth, M. Tamura, D. Uhlinger, 1989, Archives of biochemistry and biophysics.

Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst.

J. Lambeth, S. Tyagi, D. Burnham, 1988, The Journal of biological chemistry.

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.

A. Merrill, R. Bell, J. Lambeth, 1986, The Journal of biological chemistry.

Reconstitution and characterization of the human neutrophil respiratory burst oxidase using recombinant p47-phox, p67-phox and plasma membrane.

J. Lambeth, N. Neckelmann, K. Inge, 1992, Biochemical and biophysical research communications.

Selective activation of phospholipase D2 by unsaturated fatty acid

S. Ryu, P. Suh, J. Lambeth, 1999, FEBS letters.

Studies on electron transfer from general acyl-CoA dehydrogenase to electron transfer flavoprotein.

J. Lambeth, C. Hall, 1980, The Journal of biological chemistry.

Photoreactive cardiolipin analogues.

J. Lambeth, G. Powell, W. Fowler, 1988, Chemistry and physics of lipids.

The superoxide-generating respiratory burst oxidase of human neutrophil plasma membrane. Phosphatidylserine as an effector of the activated enzyme.

J. Lambeth, M. Tamura, S. Tyagi, 1988, The Journal of biological chemistry.

Cholesterol pools in rat adrenal mitochondria: use of cholesterol oxidase to infer a complex pool structure.

V. Stevens, J. Lambeth, T. Xu, 1992, Endocrinology.

On the mechanism of inhibition of the neutrophil respiratory burst oxidase by a peptide from the C-terminus of the large subunit of cytochrome b558.

J. Lambeth, S. Tyagi, D. Uhlinger, 1995, Biochemistry.

Cell-free translocation of recombinant p47-phox, a component of the neutrophil NADPH oxidase: effects of guanosine 5'-O-(3-thiotriphosphate), diacylglycerol, and an anionic amphiphile.

J. Lambeth, N. Neckelmann, S. Tyagi, 1992, Biochemistry.

The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

H. Motoshima, J. Lambeth, B. Goldstein, 2004, Molecular and Cellular Biology.

Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.

J. Lambeth, B. Diebold, Aiming Sun, 2015, ACS medicinal chemistry letters.

Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors.

J. Lambeth, D. Edmondson, D. Perry, 1992, Journal of immunology.

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets.

K. Krause, L. Scapozza, J. Lambeth, 2009, Antioxidants & redox signaling.

Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation*

J. Lambeth, B. Kalyanaraman, L. Verplank, 2016, The Journal of Biological Chemistry.

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain†

T. Kawahara, J. Lambeth, Heather M. Jackson, 2010, Biochemistry.

NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress.

J. Lambeth, B. Diebold, Susan M E Smith, 2015, Antioxidants & redox signaling.

Activation of the respiratory burst oxidase in neutrophils: On the role of membrane-derived second messengers, Ca++, and protein kinase C

J. Lambeth, J. Lambeth, 1988, Journal of bioenergetics and biomembranes.

The neutrophil NADPH oxidase.

J. Lambeth, W. Nauseef, B. Babior, 2002, Archives of biochemistry and biophysics.

Phosphatidylcholine vesicle reconstituted cytochrome P-450scc. Role of the membrane in control of activity and spin state of the cytochrome.

J. Lambeth, H. Kamin, D. Seybert, 1980, The Journal of biological chemistry.

Cholesterol sulfate: a naturally-occurring inhibitor of cholesterol side-chain cleavage which functions at the level of intramitochondrial cholesterol translocation.

J. Lambeth, X. X. Xu, 1989, Endocrine research.

Regulation of mitochondrial compartment volumes in rat adrenal cortex by ether stress.

V. Stevens, D. Tribble, J. Lambeth, 1985, Archives of biochemistry and biophysics.

Oxygen dependence of adrenal cortex cholesterol side chain cleavage. Implications in the rate-limiting steps in steroidogenesis.

T. Aw, V. Stevens, J. Lambeth, 1984, The Journal of biological chemistry.

Nox1 Overexpression Potentiates Angiotensin II-Induced Hypertension and Vascular Smooth Muscle Hypertrophy in Transgenic Mice

D. Weiss, H. Schmidt, K. Griendling, 2005, Circulation.

Formation and mode of action of flavoproteins.

A. Merrill, J. Lambeth, D. Edmondson, 1981, Annual review of nutrition.

NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells.

Kevin F Krenitsky, J. Lambeth, R. Hemendinger, 2003, American journal of physiology. Cell physiology.

NOX 5 NAD ( P ) H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells

Kevin F Krenitsky, J. Lambeth, R. Hemendinger, 2003 .

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

R. Rodenburg, J. Arbiser, L. Oberley, 2007, The Journal of clinical investigation.

Immunocytochemical localization of protein kinase C in resting and activated human neutrophils

Z. Kiss, J. Lambeth, J. Kuo, 1987, FEBS letters.

Altered diacylglycerol level and metabolism in neutrophils from patients with localized juvenile periodontitis

J. Lambeth, T. V. Van Dyke, C. Champagne, 1992, Infection and immunity.

On the biological occurrence and regulation of 1-acyl and 1-O-alkyl-diradylglycerols in human neutrophils. Selective destruction of diacyl species using Rhizopus lipase.

J. Lambeth, S. Tyagi, D. Burnham, 1989, The Journal of biological chemistry.

Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds.

Y. Hannun, V. Stevens, A. Merrill, 1989, Biochemistry.

Nox4 B-loop Creates an Interface between the Transmembrane and Dehydrogenase Domains*

T. Kawahara, J. Lambeth, Heather M. Jackson, 2010, The Journal of Biological Chemistry.

NOX enzymes as novel targets for drug development

K. Krause, J. Lambeth, R. Clark, 2008, Seminars in Immunopathology.

Characterization of the flavoprotein domain of gp91phox which has NADPH diaphorase activity.

J. Lambeth, C. Han, E. Kim, 2001, Journal of biochemistry.

Stabilization of human neutrophil NADPH oxidase activated in a cell-free system by cytosolic proteins and by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide.

J. Lambeth, J. Curnutte, M. Tamura, 1992, The Journal of biological chemistry.

Membrane association of Rac is required for high activity of the respiratory burst oxidase.

A. Abo, J. Lambeth, J. Freeman, 1996, Biochemistry.

Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes

T. Kawahara, J. Lambeth, M. Quinn, 2007, BMC Evolutionary Biology.

Rac Binding to p67 phox

M. Hirshberg, J. Lambeth, J. Freeman, 1997, The Journal of Biological Chemistry.

Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation

Lambeth, K. Krause, Moo-Yeol Lee, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5.

Erwin G. Van Meir, J. Lambeth, G. Cheng, 2001, Gene.

Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes

T. Kawahara, J. Lambeth, J. Lambeth, 2007, BMC Evolutionary Biology.

Cytochrome b558 from (bovine) granulocytes. Partial purification from Triton X-114 extracts and properties of the isolated cytochrome.

J. Lambeth, J. M. Kinkade, S. Pember, 1984, The Journal of biological chemistry.

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

J. Lambeth, B. Diebold, Y. Nisimoto, 2014, Biochemistry.

Cholesterol sulfate is a naturally occurring inhibitor of steroidogenesis in isolated rat adrenal mitochondria.

J. Lambeth, X. X. Xu, 1989, The Journal of biological chemistry.

Cholesterol sulfate inhibits adrenal mitochondrial cholesterol side chain cleavage at a site distinct from cytochrome P-450scc. Evidence for an intramitochondrial cholesterol translocator.

J. Lambeth, X. X. Xu, M. Glover, 1987, The Journal of biological chemistry.

The use of model systems to study biological functions of Nox/Duox enzymes.

J. Lambeth, D. Ritsick, W. Edens, 2004, Biochemical Society symposium.

Nox1 is over‐expressed in human colon cancers and correlates with activating mutations in K‐Ras

Wenhui Liu, J. Lambeth, J. Papkoff, 2008, International journal of cancer.

Redox regulation of interleukin-4 signaling.

M. Tremblay, S. Haque, T. Kawahara, 2008, Immunity.

Increased Nox1 and hydrogen peroxide in prostate cancer

F. Marshall, M. Amin, L. Chung, 2005, The Prostate.

Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox‐mediated generation of reactive oxygen species

J. Lambeth, A. Neish, Jeffrey W Mercante, 2013, The EMBO journal.

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

Xiang-Xi Xu, J. Lambeth, T. Yi, 1998, Oncogene.

Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells.

V. Natarajan, J. Lambeth, V. Thannickal, 2009, Antioxidants & redox signaling.

Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1.

A. Young, M. Datta, Q. Yin-Goen, 2007, The American journal of pathology.

Reactive oxygen generated by Nox1 triggers the angiogenic switch

Cynthia Cohen, Susan M. Kilroy, J. Arbiser, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Acyl-CoA complexes of general acyl-CoA dehydrogenase and electron transfer flavoprotein.

J. Lambeth, H. Kamin, C. Hall, 1979, The Journal of biological chemistry.

Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells.

P. Ranjan, N. Heintz, J. Lambeth, 2006, Antioxidants & redox signaling.

Regulation of Phospholipase D by Protein Kinase C in Human Neutrophils

D. Burns, J. Lambeth, I. Lopez, 1995, The Journal of Biological Chemistry.

Introduction: Respiratory burst oxidase and its regulation

J. Lambeth, 1988, Journal of bioenergetics and biomembranes.

Cyclophilin A is a secreted growth factor induced by oxidative stress.

C. Yan, Y. Suh, B. Berk, 2000, Circulation research.

Inhibition of Phospholipase D by a Protein Factor from Bovine Brain Cytosol

S. Ryu, P. Suh, S. Bae, 1996, The Journal of Biological Chemistry.

Neutrophil phospholipase D: inhibition by Rho-GDP dissociation inhibitor and stimulation by small GTPase GDP dissociation stimulator.

J. Lambeth, E. Bowman, D. Uhlinger, 1995, Methods in enzymology.

Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein.

J. Lambeth, E. Bowman, D. Uhlinger, 1993, The Journal of biological chemistry.

Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5'-O-(3-thiotriphosphate). Activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol.

J. Lambeth, E. Bowman, S. Olson, 1991, The Journal of biological chemistry.

Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation.

J. Lambeth, S. Tyagi, D. Burnham, 1991, Journal of Biological Chemistry.

Biochemistry and cell biology of phospholipase D in human neutrophils.

J. Lambeth, S. Olson, 1996, Chemistry and physics of lipids.

Activation of phospholipase D1 by direct interaction with ADP‐ribosylation factor 1 and RalA

S. Ryu, P. Suh, J. Lambeth, 1998, FEBS letters.

Cloning and Initial Characterization of a Human Phospholipase D2 (hPLD2)

J. Lambeth, R. Arnold, I. Lopez, 1998, The Journal of Biological Chemistry.

Celltransformationbythesuperoxide-generating oxidase Mox 1

Y. Suh, D. Sorescu, K. Griendling, 2022 .

p67-phox enhances the binding of p47-phox to the human neutrophil respiratory burst oxidase complex.

K. L. Taylor, J. Lambeth, D. Uhlinger, 1994, The Journal of biological chemistry.

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals.

J. Lambeth, J. Aguirre, 2010, Free radical biology & medicine.

Fluoride activates diradylglycerol and Superoxide generation in human neutrophils via PLD/PA phosphohydrolase‐dependent and ‐independent pathways

J. Lambeth, S. Olson, S. Tyagi, 1990, FEBS letters.

A novel ecto-phosphatidic acid phosphohydrolase activity mediates activation of neutrophil superoxide generation by exogenous phosphatidic acid.

V. Stevens, J. Lambeth, T. Widlanski, 1993, The Journal of biological chemistry.

Chemical synthesis, initial conformational studies, and activity of rat steroidogenesis activator peptide and a truncated analog.

J. Lambeth, T. Xu, D. Glass, 1991, Endocrine research.

Amyloid-β and Proinflammatory Cytokines Utilize a Prion Protein-Dependent Pathway to Activate NADPH Oxidase and Induce Cofilin-Actin Rods in Hippocampal Neurons

J. Bamburg, David R. Brown, J. Lambeth, 2014, PloS one.

The use of a specific fluorescence probe to study the interaction of adrenodoxin with adrenodoxin reductase and cytochrome P-450scc.

J. Lambeth, L. Geren, J. Tuls, 1987, The Journal of biological chemistry.

Adrenodoxin interaction with adrenodoxin reductase and cytochrome P-450scc. Cross-linking of protein complexes and effects of adrenodoxin modification by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide.

J. Lambeth, L. Geren, F. Millett, 1984, The Journal of biological chemistry.

Nox1-dependent Reactive Oxygen Generation Is Regulated

J. Lambeth, B. Diebold, G. Cheng, 2006 .

Nox regulation of smooth muscle contraction.

J. Lambeth, D. Ritsick, W. Edens, 2007, Free radical biology & medicine.

Regulation of the Neutrophil Respiratory Burst Oxidase IDENTIFICATION OF AN ACTIVATION DOMAIN IN p67 phox * generation by neutrophil

J. Lambeth, Chang-Hoon Han, J. Freeman, 1998 .

Nox 3 Regulation by NOXO 1 , p 47 phox , and p 67 phox *

J. Lambeth, D. Ritsick, G. Cheng, 2004 .

NADPH-cytochrome P-450 reductase-cytochrome b5 interactions: crosslinking of the phospholipid vesicle-associated proteins by a water-soluble carbodiimide.

J. Lambeth, Y. Nisimoto, 1985, Archives of biochemistry and biophysics.

BINDING OF CHOLESTEROL AND ADRENODOXIN TO PHOSPHOLIPID VESICLE-RECONSTITUTED P-450scc

J. Lancaster, J. Lambeth, H. Kamin, 1980 .

Chapter 9 - Glycerolipids in signal transduction

S. Ryu, J. Lambeth, S. Ryu, 1996 .

Nox5 forms a functional oligomer mediated by self-association of its dehydrogenase domain.

T. Kawahara, J. Lambeth, Heather M. Jackson, 2011, Biochemistry.

Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region.

T. Kawahara, J. Lambeth, 2008, Molecular biology of the cell.

Platelet-derived growth factor stimulates phagocytosis and blocks agonist-induced activation of the neutrophil oxidative burst: a possible cellular mechanism to protect against oxygen radical damage.

J. Lambeth, L. Gooding, E. Wilson, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Diacylglycerol generation and phosphoinositide turnover in human neutrophils: effects of particulate versus soluble stimuli.

J. Lambeth, S. Tyagi, D. Uhlinger, 1989, Archives of biochemistry and biophysics.

The participation of a second molecule of adrenodoxin in cytochrome P-450-catalyzed 11beta hydroxylation.

J. Lambeth, H. Kamin, D. Seybert, 1978, Journal of Biological Chemistry.

Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

J. Lambeth, V. Thannickal, G. Cheng, 2012, Infection and Immunity.

Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells.

V. Natarajan, J. Lambeth, V. Thannickal, 2009, Antioxidants & redox signaling.