A. Shearn

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Role of AWD/Nucleoside Diphosphate Kinase in Drosophila Development

L. Timmons, A. Shearn, 2000, Journal of bioenergetics and biomembranes.

Molecular, phenotypic, and expression analysis of vein, a gene required for growth of the Drosophila wing disc.

G. Grumbling, A. Simcox, A. Shearn, 1996, Developmental biology.

A study of transfer ribonucleic acid in Neurospora. I. The attachment of amino acids and amino acid analogs.

A. Shearn, N. Horowitz, 1969, Biochemistry.

Molecular genetic analysis of Drosophila ash2, a member of the trithorax group required for imaginal disc pattern formation.

A. Shearn, A. L. Adamson, 1996, Genetics.

A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase

L. Liotta, P. Steeg, J. Biggs, 1990, Cell.

Patterns of protein synthesis in imaginal discs of drosophila melanogaster

A. Shearn, M. Rodgers, 1977, Cell.

Germline transformation using a prune cDNA rescues prune/killer of prune lethality and the prune eye color phenotype in Drosophila.

L. Timmons, A. Shearn, 1996, Genetics.

Loss-of-Function Mutations in a Glutathione S-Transferase Suppress the prune-Killer of prune Lethal Interaction

W. Ho, L. Timmons, A. Shearn, 2006, Genetics.

Specific protein modifications are altered in a temperature-sensitive Drosophila developmental mutant.

T. Lang, A. Shearn, K. Miller, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Group Required for Imaginal Disc Pattern Formation

A. Shearn, L. Amy, 2002 .

Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila.

J. Biggs, A. Shearn, C. Dearolf, 1988, Genes & development.

A study of transfer ribonucleic acid in Neurospora. II. Failure to detect transfer ribonucleic acid alterations in tyrosinase-derepressed cultures.

A. Shearn, N. Horowitz, 1969, Biochemistry.

Establishment and characterization of continuous cell lines derived from temperature-sensitive mutants ofDrosophila melanogaster

A. Simcox, A. Shearn, M. Sobeih, 1985, Somatic cell and molecular genetics.

Genetic control of imaginal disc development in Drosophila.

A. Shearn, A. Garen, 1974, Proceedings of the National Academy of Sciences of the United States of America.

In vitro growth of imaginal disks from Drosophila melanogaster.

A. Shearn, K. Davis, 1977, Science.

Developmental regulation of Drosophila imaginal disc proteins: synthesis of a heat shock protein under non-heat-shock conditions.

A. Shearn, C. Cheney, 1983, Developmental biology.

A deletion of the 3' end of the Drosophila melanogaster hsp70 gene increases stability of mutant mRNA during recovery from heat shock

A. Simcox, A. Shearn, C. Cheney, 1985, Molecular and cellular biology.

Genetic studies of mutations at two loci of Drosophila melanogaster which cause a wide variety of homeotic transformations

A. Shearn, E. Hersperger, G. Hersperger, 1987, Roux's archives of developmental biology.

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

L. Liotta, P. Steeg, H. Krutzsch, 1989, Nature.

Development of Drosophila imaginal discs in vitro: Effects of ecdysone concentration and insulin

A. Shearn, Presley F. Martin, Presley Martin, 1980 .

prune/Killer of prune: a conditional dominant lethal interaction in Drosophila.

L. Timmons, A. Shearn, 1997, Advances in genetics.

Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes.

A. Shearn, M. Phillips, Mark D. Phillips, 1990, Genetics.

ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3

A. Shearn, K. N. Byrd, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes.

C. McCallum, J. Tamkun, A. Shearn, 1998, Development.

The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger.

A. Shearn, D. LaJeunesse, N. Tripoulas, 1996, Genetics.

The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms

A. Shearn, J. Treisman, K. Amanai, 2002, Development.

Metastatic ability of Drosophila tumors depends on MMP activity.

A. Shearn, A. Page-McCaw, E. Hersperger, 2007, Developmental biology.

Mutational Dissection of Imaginal Disc Development in Drosophila melanogaster

A. Shearn, 1977 .

Imaginal disc abnormalities in lethal mutants of Drosophila.

W. Gehring, A. Shearn, T. Rice, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Mutations in the β-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain

A. Shearn, E. Arama, Z. Lev, 2000, Oncogene.

Imaginal discs can be recovered from cultured embryos mutant for the segment-polarity genes engrailed, naked and patched but not from wingless.

A. Simcox, J. Whittle, A. Shearn, 1989, Development.

The Direct Interaction Between ASH2, a Drosophila Trithorax Group Protein, and SKTL, a Nuclear Phosphatidylinositol 4-Phosphate 5-Kinase, Implies a Role for Phosphatidylinositol 4,5-Bisphosphate in Maintaining Transcriptionally Active Chromatin

A. Shearn, Mimi K Cheng, 2004, Genetics.

Genetic analysis of two allelic temperature-sensitive mutants of Drosophila melanogaster both of which are zygotic and maternal-effect lethals.

A. Shearn, E. Hersperger, G. Hersperger, 1978, Genetics.

Point Mutations in awdKpn Which Revert the Prune/Killer of Prune Lethal Interaction Affect Conserved Residues That Are Involved in Nucleoside Diphosphate Kinase Substrate Binding and Catalysis (*)

L. Timmons, A. Shearn, X. Deng, 1995, The Journal of Biological Chemistry.

Trans-regulation of thoracic homeotic selector genes of the Antennapedia and bithorax complexes by the trithorax group genes: absent, small, and homeotic discs 1 and 2

A. Shearn, D. LaJeunesse, 1995, Mechanisms of Development.

E(z): a polycomb group gene or a trithorax group gene?

A. Shearn, D. LaJeunesse, Dennis R. LaJeunesse, 1996, Development.

Drosophila brain tumor metastases express both neuronal and glial cell type markers.

A. Shearn, J. Goodliffe, S. Trunova, 2007, Developmental biology.

The defective dorsal discs gene of Drosophila is required for the growth of specific imaginal discs.

A. Simcox, A. Shearn, E. Hersperger, 1987, Developmental biology.

minidiscs encodes a putative amino acid transporter subunit required non-autonomously for imaginal cell proliferation

A. Simcox, A. Shearn, E. Hersperger, 2000, Mechanisms of Development.

Establishment of imaginal discs and histoblast nests in Drosophila

S. Cohen, A. Simcox, J. Whittle, 1991, Mechanisms of Development.

Transdetermination of Drosophila imaginal discs cultured in vitro.

A. Shearn, K. Davis, E. Hersperger, 1978, Developmental biology.

A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2.

A. Shearn, R. Lopez, J. Gildea, 2000, Genetics.

The Suppressor of Killer of prune, a unique glutathione S-transferase

A. Shearn, E. Provost, 2006, Journal of bioenergetics and biomembranes.

Genetic analysis of transdetermination in Drosophila. I. The effects of varying growth parameters using a temperature-sensitive mutation.

A. Shearn, K. Davis, E. Hersperger, 1984, Developmental biology.

Multiple Allele Approach to the Study of Genes in DROSOPHILA MELANOGASTER That Are Involved in Imaginal Disc Development.

A. Shearn, E. Hersperger, E. Pentz, 1978, Genetics.

Aspects of development of imaginal discs in a non-pupariating lethal mutant in Drosophila melanogaster

A. Shearn, J. Fristrom, C. Murphy, 1977 .

Complementation analysis of late lethal mutants of Drosophila melanogaster.

A. Shearn, 1974, Genetics.

Green fluorescent protein/beta-galactosidase double reporters for visualizing Drosophila gene expression patterns.

L. Timmons, A. Shearn, C. Fyrberg, 1997, Developmental genetics.

The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related.

A. Shearn, 1989, Genetics.

Trithorax and ASH1 Interact Directly and Associate with the Trithorax Group-Responsive bxd Region of theUltrabithorax Promoter

O. Rozenblatt-Rosen, C. Croce, S. Tillib, 1999, Molecular and Cellular Biology.

Exploring DNA structure with Cn3D.

Rebecca Pearlman, Richard Shingles, Sandra G Porter, 2007, CBE life sciences education.

Genetic and molecular analysis of hyperplastic discs, a gene whose product is required for regulation of cell proliferation in Drosophila melanogaster imaginal discs and germ cells.

J. Biggs, E. Mansfield, A. Shearn, 1994, Developmental biology.

The Enzymatic Activity of Drosophila AWD/NDP Kinase Is Necessary but Not Sufficient for Its Biological Function

P. Steeg, L. Timmons, A. Shearn, 1996, Developmental biology.

shock.mRNA during recovery from heat melanogaster hsp70 gene increases stability of A deletion of the 3' end of the Drosophila

A. Simcox, A. Shearn, C. Cheney, 2013 .

A Deletion ofthe3'EndoftheDrosophila melanogaster hsp7O GeneIncreases Stability ofMutantmRNA During Recovery fromHeatShock

A. Shearn, 1985 .

Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes

A. Shearn, E. Hersperger, E. Woodhouse, 1998, Development Genes and Evolution.

The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations.

L. Timmons, A. Shearn, J. Xu, 1993, Developmental biology.