D. Sacks

发表

Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.

R. Watson, J. Pessin, J. S. Elmendorf, 2000, Molecular endocrinology.

A1C Versus Glucose Testing: A Comparison

D. Sacks, 2011, Diabetes Care.

The IFCC Reference Measurement System for HbA1c: a 6-year progress report.

R. Little, D. Sacks, A. Mosca, 2008, Clinical chemistry.

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Å. Lernmark, G. Bakris, D. Bruns, 2002, Diabetes Care.

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

Boyd, Å. Lernmark, G. Bakris, 2002, Clinical chemistry.

Status of hemoglobin A1c measurement and goals for improvement: from chaos to order for improving diabetes care.

R. Little, D. Sacks, C. Rohlfing, 2011, Clinical chemistry.

Identification of a Conserved Negative Regulatory Sequence That Influences the Leukemogenic Activity of NOTCH1

J. Aster, S. Blacklow, W. Pear, 2006, Molecular and Cellular Biology.

IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis

D. Sacks, Matthew D. Brown, Colin D. White, 2009, FEBS letters.

Acute coronary ischemia: troponin I and T

D. Sacks, 1999, Vascular medicine.

Cardiac troponin T as a marker for myocardial ischemia in patients seen at the emergency department for acute chest pain.

E. Cook, L. Goldman, D. Sacks, 1999, American heart journal.

Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry

A. Ogurtsov, Yi-Kuo Yu, M. Gucek, 2018, Journal of The American Society for Mass Spectrometry.

Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance

Aleksey Y. Ogurtsov, Steven K. Drake, Yi-Kuo Yu, 2015, Journal of The American Society for Mass Spectrometry.

Midkine concentrations in fine‐needle aspiration of benign and malignant thyroid nodules

J. Baron, A. Remaley, E. Kebebew, 2015, Clinical endocrinology.

Differential Affinity Cross-linking of Phosphorylase Kinase Conformers by the Geometric Isomers of Phenylenedimaleimide*

D. Sacks, O. Nadeau, G. Carlson, 1997, The Journal of Biological Chemistry.

Association of Sickle Cell Trait With Hemoglobin A1c in African Americans

A. Reiner, D. Jacobs, M. Carnethon, 2017, JAMA.

A new look at screening and diagnosing diabetes mellitus.

David B Sacks, David Edelman, W. Herman, 2008, The Journal of clinical endocrinology and metabolism.

SIGNALING ELEMENTS THAT IMPACT CELL MIGRATION

B. Tunquist, Jeremy S Logue, L. Langeberg, 2011 .

Prognostic value of cardiac troponin T after noncardiac surgery: 6-month follow-up data.

E. Cook, L. Goldman, F. Lopez‐Jimenez, 1997, Journal of the American College of Cardiology.

Continuous Glucose Monitors and Automated Insulin Dosing Systems in the Hospital Consensus Guideline

R. Hovorka, D. Klonoff, B. Buckingham, 2020, Journal of diabetes science and technology.

Characteristics of calmodulin phosphorylation by the insulin receptor kinase.

D. Sacks, J. McDonald, J. Laurino, 1988, Endocrinology.

Insulin-stimulated phosphorylation of calmodulin by rat liver insulin receptor preparations.

D. Sacks, J. McDonald, 1988, The Journal of biological chemistry.

Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta.

D. Sacks, Y. Fujita-Yamaguchi, J. McDonald, 1989, The Biochemical journal.

The carboxyl terminal segment of the c-Ki-ras 2 gene product mediates insulin-stimulated phosphorylation of calmodulin and stimulates insulin-independent autophosphorylation of the insulin receptor.

K. Glenn, D. Sacks, J. McDonald, 1989, Biochemical and biophysical research communications.

Calmodulin as Substrate for Insulin-Receptor Kinase: Phosphorylation by Receptors From Rat Skeletal Muscle

D. Sacks, J. McDonald, David B Sacks, 1989, Diabetes.

Tyrosine-phosphorylated calmodulin has reduced biological activity.

R. Sharma, R. Thoma, J. Williams, 1994, Archives of biochemistry and biophysics.

Phosphorylation of calmodulin by the epidermal-growth-factor-receptor tyrosine kinase.

A. Benguría, D. Sacks, M. Martínez-Pastor, 1994, European journal of biochemistry.

Identification of insulin-stimulated phosphorylation sites on calmodulin.

R. Thoma, D. Sacks, J. Joyal, 1996, Biochemistry.

Calmodulin Activates Phosphatidylinositol 3-Kinase*

M. White, D. Burks, C. Vlahos, 1997, The Journal of Biological Chemistry.

Implications of the revised criteria for diagnosis and classification of diabetes mellitus.

D. Sacks, 1997, Clinical chemistry.

Targeting of calcium:calmodulin signals to the cytoskeleton by IQGAP1.

D. Sacks, S. Moss, S. Bolsover, 2007, Cell calcium.

Regulation of MAP kinase signaling by calcium.

David B Sacks, D. Sacks, Colin D. White, 2010, Methods in molecular biology.

Functional interactions between calmodulin and estrogen receptor-α

D. Sacks, Lu Li, 2007 .

The Transcriptional Activity of Estrogen Receptor-α Is Dependent on Ca2+/Calmodulin*

D. Sacks, Lu Li, Zhigang Li, 2005, Journal of Biological Chemistry.

IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity *

D. Sacks, Zhigang Li, S. Sayedyahossein, 2016, The Journal of Biological Chemistry.

Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2.

F. Soncin, D. Sacks, S. Calderwood, 2003, Biochemical and biophysical research communications.

Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.

D. Sacks, Colin D. White, Zhigang Li, 2011, The Biochemical journal.

PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase.

D. Sacks, J. Madara, J. Turner, 1999, American journal of physiology. Cell physiology.

IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration

Suyong Choi, D. Sacks, Narendra Thapa, 2013, The EMBO journal.

IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma

R. Odze, D. Sacks, D. Gnatenko, 2010, BMC gastroenterology.

Self-association of IQGAP1

D. Sacks, D. Crimmins, Jian-guo Ren, 2005, Journal of Biological Chemistry.

Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol.

D. Sacks, E. Selvin, A. Saenger, 2018, Clinical chemistry.

Elevation of troponin I levels in patients without evidence of myocardial injury.

S. Goldhaber, D. Sawyer, D. Sacks, 1997, JAMA.

Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring

R. Beck, Aaron J. Kowalski, L. Heinemann, 2018, Diabetes Care.

IQGAP1 controls tight junction formation through differential regulation of claudin recruitment

I. Mellinghoff, I. Vivanco, S. Salvarezza, 2015, Journal of Cell Science.

Call for Action: Journals Need to Insist on Full Reporting of the Analytical Characteristics of Biomarkers.

Zhen Zhao, David B Sacks, D. Sacks, 2020, Laboratory medicine.

Assay Development in Clinical Pathology

D. Sacks, Z. Zhao, 2014 .

Combining HbA1c and glycated albumin improves detection of dysglycaemia in mixed-ancestry South Africans

A. Kengne, R. Erasmus, T. Matsha, 2022, EClinicalMedicine.

EurA1c: The European HbA1c Trial to Investigate the Performance of HbA1c Assays in 2166 Laboratories across 17 Countries and 24 Manufacturers by Use of the IFCC Model for Quality Targets.

Thomas P. Smith, R. Little, R. Erasmus, 2018, Clinical chemistry.

Hemoglobin A1c and Race: Should Therapeutic Targets and Diagnostic Cutoffs Differ among Racial Groups?

D. Sacks, 2016, Clinical chemistry.

HbA1c: what do the numbers really mean?

R. Little, D. Sacks, 2011, The Lancet.

The diagnosis of diabetes is changing: how implementation of hemoglobin A1c will impact clinical laboratories.

D. Sacks, 2009, Clinical chemistry.

Diagnosis of Gestational Diabetes Mellitus Will Be Flawed until We Can Measure Glucose.

D. Bruns, D. Sacks, B. Metzger, 2020, Clinical chemistry.

Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury.

S. Lipsitz, S. Sallan, N. Rifai, 1997, Circulation.

Current status of US programs for training clinical laboratory scientists and anticipated impact of healthcare reform.

D. Sacks, M. Scott, 1995, Clinical chemistry.

Troponin T as a marker for myocardial ischemia in patients undergoing major noncardiac surgery.

E. Cook, L. Goldman, K. Kuntz, 1996, The American journal of cardiology.

Global harmonization of hemoglobin A1c.

D. Sacks, 2005, Clinical chemistry.

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer

M. Raffeld, A. Wellstein, J. Baron, 2016, PloS one.

E-cadherin-mediated Cell-Cell Attachment Activates Cdc42*

D. Sacks, Zhigang Li, Stella H. Kim, 2000, The Journal of Biological Chemistry.

Hepatocyte Growth Factor-induced Asef-IQGAP1 Complex Controls Cytoskeletal Remodeling and Endothelial Barrier*

Y. Kawasaki, T. Akiyama, A. Birukova, 2014, The Journal of Biological Chemistry.

Bilateral Duane's syndrome.

D. Sacks, J. Goldstein, 1977, Journal of pediatric ophthalmology.

A PAK6–IQGAP1 complex promotes disassembly of cell–cell adhesions

D. Sacks, C. Wells, Sally Fram, 2013, Cellular and Molecular Life Sciences.

Calmodulin Binds to p21Cip1 and Is Involved in the Regulation of Its Nuclear Localization*

E. Pérez-Payá, O. Bachs, N. Agell, 1999, The Journal of Biological Chemistry.

Higher degree of glycation of hemoglobin S compared to hemoglobin A measured by mass spectrometry: Potential impact on HbA1c testing.

R. Little, D. Sacks, C. Rohlfing, 2016, Clinica chimica acta; international journal of clinical chemistry.

International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) IFCC Scientific Division

D. Sacks, A. Mosca, W. G. John, 2007 .

Hemoglobin variants and hemoglobin A1c analysis: problem solved?

D. Sacks, 2003, Clinical chemistry.

Time to positivity of a rapid bedside assay for cardiac-specific troponin T predicts prognosis in acute coronary syndromes: a Thrombolysis in Myocardial Infarction (TIMI) 11A substudy.

E. Antman, E. Braunwald, C. Cannon, 1998, Journal of the American College of Cardiology.

Effect of Antiresorptive Therapy on Day-to-Day Variation of Urinary Free Deoxypyridinoline Excretion

D. Sacks, 1998 .

Diagnosis of gestational diabetes mellitus: it is time for international consensus.

D. Sacks, 2014, Clinical chemistry.

Tests of glycemia in diabetes.

Charles M Peterson, Randie R Little, David B Sacks, 1995, Diabetes care.

Monitoring Glycemic Control in End-Stage Renal Disease: What Should Be Measured?

D. Sacks, E. Selvin, 2017, Clinical chemistry.

Correlation between Hemoglobin A1c (HbAlc) and Average Blood Glucose: Can HbAlc Be Reported as Estimated Blood Glucose Concentration?

D. Sacks, 2007, Journal of diabetes science and technology.

The pathogenesis of type II diabetes mellitus. A polygenic disease.

D. Sacks, J. McDonald, David B. Sacks, 1996, American journal of clinical pathology.

The NGSP: Over 20 Years of Improving HbA1c Measurement

R. Little, D. Sacks, C. Rohlfing, 2019 .

Plasmonic chip tackles type 1 diabetes diagnosis.

L. Kricka, D. Sacks, 2015, Clinical chemistry.

The enigma of insulin resistance and hypertension.

D. Sacks, J. McDonald, 1988, The American journal of medicine.

IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells

G. E. Fernandez, N. Prasadarao, D. Sacks, 2012, Cellular microbiology.

Molecular manipulation of autoantibody testing in type 1 diabetes: two for one.

Å. Lernmark, D. Sacks, 2001, Clinical chemistry.

IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation

D. Sacks, M. Hartnett, Haibo Wang, 2020, Angiogenesis.

Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro

F. Mégraud, P. Dubus, D. Sacks, 2016, Oncotarget.

HbA1c: how do we measure it and what does it mean?

R. Little, D. Sacks, 2009, Current opinion in endocrinology, diabetes, and obesity.

IQGAP1 Binds to Estrogen Receptor-α and Modulates Its Function*

D. Sacks, Zhigang Li, H. Erdemir, 2014, The Journal of Biological Chemistry.

Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A1c With Glycated Albumin

A. Sherman, D. Sacks, S. Chung, 2020, Diabetes Care.

It’s Time for a Better Blood Collection Tube to Improve the Reliability of Glucose Results

D. Bruns, D. Sacks, A. Horvath, 2012, Diabetes Care.

The Ras GTPase-activating-like Protein IQGAP1 Mediates Nrf2 Protein Activation via the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)-ERK Pathway

A. Kong, Jung-Hwan Kim, D. Sacks, 2013, The Journal of Biological Chemistry.

The Marker for Long-Term Glycemic Control of Diabetes Mellitus

D. Sacks, Aleksandar Babic, 2003 .

Investigation of 2 Models to Set and Evaluate Quality Targets for Glycated Hemoglobin: Biological Variation and Sigma-Metrics

G. Roglić, R. Little, I. Takei, 2015 .

IQGAP1 Regulates Salmonella Invasion through Interactions with Actin, Rac1, and Cdc42*

L. Bry, D. Sacks, Matthew D. Brown, 2007, Journal of Biological Chemistry.

Iron dose‐dependent differentiation and enucleation of human erythroblasts in serum‐free medium

Y. T. Lee, Jeffery L. Miller, D. Sacks, 2016, Journal of tissue engineering and regenerative medicine.

IQGAP1 binds the Axl receptor kinase and inhibits its signaling.

D. Sacks, Zhigang Li, L. Gorisse, 2018, The Biochemical journal.

Phosphorylation selectively increases triiodothyronine receptor homodimer binding to DNA.

A. Sugawara, J. Baxter, D. Sacks, 1994, The Journal of biological chemistry.

Variability in the Relationship of Hemoglobin A1c and Average Glucose Concentrations: How Much Does Race Matter?

D. Sacks, E. Selvin, 2017, Annals of Internal Medicine.

Ca2+ regulates calmodulin binding to IQ motifs in IRS-1.

M. White, D. Burks, D. Sacks, 1996, Biochemistry.

Phosphorylation by casein kinase II alters the biological activity of calmodulin.

J. Williams, D. Sacks, J. McDonald, 1992, The Biochemical journal.

Detrimental Effects of Not Using International Reference Materials to Calibrate Cystatin C Assays.

D. Sacks, Zhen Zhao, 2016, Clinical chemistry.

Actin Pedestal Formation by Enteropathogenic Escherichia coli Is Regulated by IQGAP1, Calcium, and Calmodulin*

L. Bry, D. Sacks, Matthew D. Brown, 2008, Journal of Biological Chemistry.

Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A.

A. Bresnick, C. McCulloch, D. Sacks, 2008, Molecular biology of the cell.

Rap 1 Activation in Collagen Phagocytosis Is Dependent on Nonmuscle Myosin IIA

A. Bresnick, C. McCulloch, D. Sacks, 2008 .

The utility of patient age in evaluating prostate cancer.

W. Welch, K. Loughlin, D. Sacks, 1997, American journal of clinical pathology.

Calmodulin-specific monoclonal antibodies inhibit DNA replication in mammalian cells.

D. Sacks, G. Reddy, W. Reed, 1992, Biochemistry.

The mechanism of insulin action.

D. Sacks, 1993, Clinical biochemistry.

Refining Measurement of Hemoglobin A1c.

J. Lachin, D. Sacks, I. Bebu, 2017, Clinical chemistry.

Point-of-Care Hemoglobin A1c.

D. Sacks, M. O’Brien, 2019, JAMA.

Elucidation of the Interaction of Calmodulin with the IQ Motifs of IQGAP1*

D. Sacks, Zhigang Li, 2003, The Journal of Biological Chemistry.

Binding of IRS proteins to calmodulin is enhanced in insulin resistance.

D. Sacks, J. Joyal, Z. Li, 2000, Biochemistry.

Cell-Cell Interaction | Cadherin Signaling

D. Sacks, Andrew C. Hedman, Andrew C Hedman, 2021, Encyclopedia of Biological Chemistry III.

Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.

L. Bry, D. Sacks, Philip T. Chen, 2001, Clinical chemistry.

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

D. Sacks, G. Kreitzer, W. Muller, 2019, The Journal of experimental medicine.

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation

D. Sacks, M. Goldberg, B. B. Herrera, 2015, PLoS pathogens.

ACELL September 46/3

D. Sacks, J. Madara, J. Turner, 1999 .

PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase.

D. Sacks, J. Madara, J. Turner, 1999, The American journal of physiology.

Cardiac troponin T and point-of-care testing for myocardial infarction.

E. Antman, D. Sacks, 1995 .

Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells

M. Ferrer, Noel Southall, J. Marugan, 2022, Scientific Reports.

Response to Comment on Bergenstal et al. Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring. Diabetes Care 2018;41:2275–2280

R. Beck, Aaron J. Kowalski, L. Heinemann, 2018, Diabetes Care.

IQGAP1 Regulates Endothelial Barrier Function via EB1-Cortactin Cross Talk

A. Birukova, X. Tian, D. Sacks, 2014, Molecular and Cellular Biology.

Role of IQGAP1 in endothelial barrier enhancement caused by OxPAPC.

A. Birukova, X. Tian, D. Sacks, 2016, American journal of physiology. Lung cellular and molecular physiology.

Evaluation of a rapid bedside assay for detection of serum cardiac troponin T.

E. Antman, D. Sacks, C. Grudzien, 1995, JAMA.

IQGAP1 binds to YAP and modulates its transcriptional activity

D. Sacks, Zhigang Li, S. Sayedyahossein, 2016 .

Commentary on a Case of Unexpected Hyperglycemia.

D. Sacks, 2021, Clinical chemistry.

The Interaction of Calmodulin with Novel Target Proteins

D. Sacks, K. Chun, 2000 .

Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies.

D. Sacks, J. McDonald, J. Ladenson, 1991, Analytical biochemistry.

IQGAP1 in cellular signaling: bridging the GAP.

D. Sacks, Matthew D. Brown, 2006, Trends in cell biology.

Proteomic Analysis of Ischemia-Reperfusion Injury upon Human Liver Transplantation Reveals the Protective Role of IQGAP1*S

S. Jenna, P. Metrakos, D. Sacks, 2006, Molecular & Cellular Proteomics.

IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis

N. Rahimi, D. Sacks, David B. Sacks, 2008, PloS one.

IQGAP1 modulates activation of B-Raf

D. Sacks, Zhigang Li, David B. Sacks, 2007, Proceedings of the National Academy of Sciences.

IQGAP1 Binds Rap1 and Modulates Its Activity*

Ha-won Jeong, D. Sacks, Matthew D. Brown, 2004, Journal of Biological Chemistry.

IQGAP1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling

D. Sacks, Monideepa Roy, Zhigang Li, 2005, Molecular and Cellular Biology.

Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin.

A. Persechini, D. Sacks, J. McDonald, 1992, Biochemical and biophysical research communications.

Phosphorylation of calmodulin by plasma-membrane-associated protein kinase(s).

A. Benguría, D. Sacks, J. Joyal, 1995, European journal of biochemistry.

Insulin-dependent phosphorylation of calmodulin in rat hepatocytes.

D. Sacks, J. Joyal, 1994, The Journal of biological chemistry.

Alteration of calmodulin-protein interactions by a monoclonal antibody to calmodulin.

D. Sacks, 1994, Biochimica et biophysica acta.

Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α.

R. Nussinov, Jian Zhang, Mingzhen Zhang, 2018, The journal of physical chemistry. B.

Effects of cationic polypeptides on the activity, substrate interaction, and autophosphorylation of casein kinase II: a study with calmodulin.

D. Sacks, J. McDonald, 1992, Archives of biochemistry and biophysics.

Insulin-stimulated phosphorylation of calmodulin.

D. Sacks, J. McDonald, H. Davis, 1992, The Biochemical journal.

The biology of IQGAP proteins: beyond the cytoskeleton

D. Sacks, Jessica Smith, Jessica M Smith, 2015, EMBO reports.

IQGAP1 and its binding proteins control diverse biological functions.

David B Sacks, D. Sacks, Colin D. White, 2012, Cellular signalling.

IQGAP1 Protein Binds Human Epidermal Growth Factor Receptor 2 (HER2) and Modulates Trastuzumab Resistance*

D. Dillon, D. Sacks, Colin D. White, 2011, The Journal of Biological Chemistry.

MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation*

R. Annan, D. Mcnulty, D. Sacks, 2011, The Journal of Biological Chemistry.

IQGAP1 Stimulates Proliferation and Enhances Tumorigenesis of Human Breast Epithelial Cells*

David B Sacks, Ha-won Jeong, D. Sacks, 2008, Journal of Biological Chemistry.

The Effect of IQGAP1 on XenopusEmbryonic Ectoderm Requires Cdc42*

D. Sacks, S. Sokol, Zhigang Li, 2001, The Journal of Biological Chemistry.

IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton

D. Sacks, M. W. Briggs, 2003, FEBS letters.

The role of scaffold proteins in MEK/ERK signalling.

D. Sacks, 2006, Biochemical Society transactions.

IQGAP 1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling

D. Sacks, Monideepa Roy, Zhigang Li, 2005 .

IQGAP1 and Calmodulin Modulate E-cadherin Function*

D. Sacks, M. Brenner, J. Higgins, 1999, The Journal of Biological Chemistry.

Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge.

N. Ahn, K. Anseth, M. Morphew, 2013, Developmental cell.

Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism

A. M. Kozlov, D. Sacks, L. Dagnino, 2021, The Journal of biological chemistry.

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

R. Germain, D. Kastner, D. Sacks, 2012, Nature.

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

D. Bruns, D. Goldstein, D. Sacks, 2002, Clinical chemistry.

Compartmentalised MAPK pathways.

D. Sacks, M. D. Brown, Michael D. Brown, 2008, Handbook of experimental pharmacology.

IQGAP1 Promotes Cell Motility and Invasion*

A. Ridley, D. Sacks, J. Mataraza, 2003, Journal of Biological Chemistry.

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

R. Annan, D. Sacks, C. Wagner, 2020, The Journal of Biological Chemistry.

Calmodulin binds HER2 and modulates HER2 signaling.

D. Sacks, Colin D. White, Zhigang Li, 2011, Biochimica et biophysica acta.

Calmodulin activates the Hippo signaling pathway by promoting LATS1 kinase–mediated inhibitory phosphorylation of the transcriptional coactivator YAP

D. Sacks, Zhigang Li, L. Gorisse, 2022, The Journal of biological chemistry.

The IQGAP1-Rac1 and IQGAP1-Cdc42 Interactions

H. Mott, D. Owen, D. Sacks, 2008, Journal of Biological Chemistry.

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.

D. Sacks, V. Boyapati, Jing Liu, 2016, Structure.

IQGAP1 Integrates Ca2+/Calmodulin and B-Raf Signaling*

D. Sacks, Jian-guo Ren, Zhigang Li, 2008, Journal of Biological Chemistry.

Calmodulin Modulates the Interaction between IQGAP1 and Cdc42

S. Carr, R. Annan, D. Sacks, 1997, The Journal of Biological Chemistry.

The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration

Y. Chien, Ha-won Jeong, D. Sacks, 2009, PLoS pathogens.

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2018, The Journal of Biological Chemistry.

IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins

D. Sacks, Zhigang Li, Louise Thines, 2023, Cells.

Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling

C. McCulloch, D. Sacks, A. Wilde, 2020, Molecular biology of the cell.

IQGAP1 Promotes Neurite Outgrowth in a Phosphorylation-dependent Manner*

R. Annan, C. Hall, L. Lim, 2005, Journal of Biological Chemistry.

IQGAP proteins are integral components of cytoskeletal regulation

D. Sacks, Michael W Briggs, David B Sacks, 2003, EMBO reports.

Executive summary. The National Academy of Clinical Biochemistry Laboratory Medicine Practice Guideline: evidence-based practice for point-of-care testing.

William Clarke, David B Sacks, Robert L Sautter, 2007, Clinica chimica acta; international journal of clinical chemistry.

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

Sonia Sharma, P. Hogan, A. Rao, 2011, Proceedings of the National Academy of Sciences.

Detection of unsuspected myocardial necrosis by rapid bedside assay for cardiac troponin T.

E. Antman, R. Mitchell, D. Sacks, 1997, American heart journal.

IQGAPs choreograph cellular signaling from the membrane to the nucleus.

D. Sacks, Jessica Smith, Jessica M Smith, 2015, Trends in cell biology.

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells.

S. Koch, D. Sacks, A. Skerra, 2009, Molecular biology of the cell.

Active Rap1‐mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells

G. Hageman, D. Sacks, C. Pappas, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions

M. S. Kirkman, D. Sacks, Kerry J. Welsh, 2016, Diabetes Care.

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

Suyong Choi, D. Sacks, S. Sayedyahossein, 2016, Nature Cell Biology.

Absence of IQGAP1 Protein Leads to Insulin Resistance*

D. Sacks, B. Chawla, Zhigang Li, 2017, The Journal of Biological Chemistry.

Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

R. Annan, D. Mcnulty, D. Sacks, 2020, The Journal of Biological Chemistry.

IQGAP1-mediated Stimulation of Transcriptional Co-activation by β-Catenin Is Modulated by Calmodulin*

Michael W. Briggs, D. Sacks, Zhigang Li, 2002, The Journal of Biological Chemistry.

Trends in Prevalence and Control of Diabetes in the United States, 19881994 and 19992010

J. Coresh, D. Sacks, E. Selvin, 2014, Annals of Internal Medicine.

Screening for diabetes: is it warranted?

D. Sacks, R. Greenberg, 2002, Clinica chimica acta; international journal of clinical chemistry.

Reciprocal Regulation of Endothelial Nitric-oxide Synthase by Ca2+-Calmodulin and Caveolin*

D. Sacks, T. Michel, J. Michel, 1997, The Journal of Biological Chemistry.

Calmodulin influences MAPK signaling by binding KSR1

D. Sacks, Swetha Parvathaneni, Zhigang Li, 2021, The Journal of biological chemistry.

Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

Å. Lernmark, G. Bakris, D. Bruns, 2011, Clinical chemistry.

The Need for Accuracy in Hemoglobin A1c Proficiency Testing: Why the Proposed CLIA Rule of 2019 Is a Step Backward

David Aron, David C Klonoff, Robert M Cohen, 2019, Journal of diabetes science and technology.

The National Glycohemoglobin Standardization Program: Over 20 Years of Improving Hemoglobin A1c Measurement.

R. Little, D. Sacks, C. Rohlfing, 2019, Clinical chemistry.

A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study

M. Tulloch-Reid, D. Sacks, S. Chung, 2015, Diabetes Care.

Evaluation of hemoglobin A1c measurement by Capillarys 2 electrophoresis for detection of abnormal glucose tolerance in African immigrants to the United States.

R. Little, D. Sacks, Zhen Zhao, 2015, Clinica chimica acta; international journal of clinical chemistry.

Detection of Abnormal Glucose Tolerance in Africans Is Improved by Combining A1C With Fasting Glucose: The Africans in America Study

M. Tulloch-Reid, D. Sacks, S. Chung, 2014, Diabetes Care.

Interpretation of hemoglobin A1c values.

D. Sacks, W. G. John, D B Sacks, 2014, JAMA.

Comparing analytic performance criteria: evaluation of HbA1c certification criteria as an example.

C. Parvin, R. Little, D. Sacks, 2014, Clinica chimica acta; international journal of clinical chemistry.

Reporting hemoglobin A1c: do the units matter?

D. Sacks, 2013, Clinical chemistry.

Hemoglobin A1c in Diabetes: Panacea or Pointless?

D. Sacks, 2012, Diabetes.

Measurement of hemoglobin A(1c): a new twist on the path to harmony.

D. Sacks, 2012, Diabetes care.

Measuring and reporting hemoglobin A1c.

D. Sacks, 2012, Clinical biochemistry.

The national glycohemoglobin standardization program: a five-year progress report.

G L Myers, D. Goldstein, R. Little, 2001, Clinical chemistry.

Multicentre evaluation of the Premier Hb9210 HbA1c analyser

R. Little, D. Sacks, E. Lenters-Westra, 2015, Clinical chemistry and laboratory medicine.

Tight glucose control in the intensive care unit: are glucose meters up to the task?

David B Sacks, David E Bruns, James C Boyd, 2009, Clinical chemistry.

Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis.

D. Sacks, T. Michel, D. Greif, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Calmodulin Enhances the Stability of the Estrogen Receptor*

D. Sacks, J. Joyal, Zhigang Li, 2001, The Journal of Biological Chemistry.

Both Calmodulin and the Unconventional Myosin Myr4 Regulate Membrane Trafficking Along the Recycling Pathway of MDCK Cells

K. Paiha, L. Huber, D. Sacks, 2000, Traffic.

Analysis of phosphorylation and mutation of tyrosine residues of calmodulin on its activation of the erythrocyte Ca(2+)-transporting ATPase.

D. Sacks, D. Kosk-Kosicka, Z. Li, 1996, European journal of biochemistry.

IQGAP1 Is a Component of Cdc42 Signaling to the Cytoskeleton*

D. Sacks, Zhigang Li, Jennifer M Swart-Mataraza, 2002, The Journal of Biological Chemistry.

B-Raf autoinhibition in the presence and absence of 14-3-3.

R. Nussinov, Mingzhen Zhang, D. Sacks, 2021, Structure.

Protein scaffolds in MAP kinase signalling.

D. Sacks, Matthew D. Brown, 2009, Cellular signalling.

IQGAP1 Integrates Ca2+/Calmodulin and Cdc42 Signaling*

D. Sacks, J. Joyal, Y. Ho, 1999, The Journal of Biological Chemistry.

Haemoglobin A1c analysis in the management of patients with diabetes: from chaos to harmony

D. Sacks, A. Berg, A H Berg, 2008, Journal of Clinical Pathology.

Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells.

M. Menon, D. Sacks, J. Mataraza, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group

R. Little, D. Sacks, W. G. John, 2007, Clinical chemistry and laboratory medicine.

Investigation of 2 models to set and evaluate quality targets for hb a1c: biological variation and sigma-metrics.

Cas Weykamp, Erna Lenters-Westra, Randie R Little, 2015, Clinical chemistry.

Thrombin-induced phosphorylation of MARCKS does not alter its interactions with calmodulin or actin.

D. Sacks, H. Davis, Y. Zhao, 2000, Cellular signalling.

The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

D. Sacks, Louise Thines, Francis J Roushar, 2023, The Journal of cell biology.

AKAP220 Protein Organizes Signaling Elements That Impact Cell Migration*

B. Tunquist, Jeremy S Logue, L. Langeberg, 2011, The Journal of Biological Chemistry.

Glycated Albumin Identifies Prediabetes Not Detected by Hemoglobin A1c: The Africans in America Study.

M. Tulloch-Reid, D. Sacks, S. Chung, 2016, Clinical chemistry.

E6AP and Calmodulin Reciprocally Regulate Estrogen Receptor Stability*

P. Howley, D. Sacks, Lu Li, 2006, Journal of Biological Chemistry.

Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras

D. Sacks, Zhigang Li, Chase J. Morgan, 2019, Scientific Reports.

Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells

D. Sacks, S. Sayedyahossein, Andrew C Hedman, 2019, Molecular biology of the cell.

Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration

M. Gunzer, D. Sacks, W. Muller, 2020, The Journal of experimental medicine.

Calmodulin Regulates the Transcriptional Activity of Estrogen Receptors

D. Sacks, Lu Li, Zhigang Li, 2003, The Journal of Biological Chemistry.

β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion via Rap1 and IQGAP1

G. M. Di Guglielmo, D. Sacks, A. Babwah, 2013, PloS one.

Comparing multiple measures of glycemia: how to transition from biomarker to diagnostic test?

D. Sacks, R. Cohen, 2012, Clinical chemistry.

Measurement of Hemoglobin A1c

D. Sacks, 2012, Diabetes Care.

The Surveillance Error Grid

Boris Kovatchev, David C Klonoff, David B Sacks, 2014, Journal of diabetes science and technology.

IQGAP1 Binds ERK2 and Modulates Its Activity*

D. Sacks, Monideepa Roy, Zhigang Li, 2004, Journal of Biological Chemistry.

Diabetes: advances and controversies.

A. Goldfine, D. Sacks, V. Fonseca, 2011, Clinical chemistry.

Therapy: Intensive glucose control in the ICU: is SUGAR NICE?

D. Sacks, 2009, Nature Reviews Endocrinology.

Cross-sectional Analysis of AGE-CML, sRAGE, and esRAGE with Diabetes and Cardiometabolic Risk Factors in a Community-Based Cohort.

R. Christenson, D. Sacks, C. Rebholz, 2017, Clinical chemistry.

IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton

D. Sacks, Colin D. White, Hugh Kim, 2011, FEBS letters.

Gaps in the glycation gap hypothesis.

D. Nathan, J. Lachin, D. Sacks, 2011, Clinical chemistry.

Ca2+-dependent Switch of Calmodulin Interaction Mode with Tandem IQ motifs in The Scaffolding Protein IQGAP1.

R. Nussinov, Mingzhen Zhang, D. Sacks, 2019, Biochemistry.

Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II.

M. White, R. Thoma, D. Sacks, 1993, The Journal of biological chemistry.

Biomarkers for the diagnosis of heart failure in people with diabetes: A consensus report from diabetes technology society.

Connie M. Rhee, G. A. Fleming, Lawrence A Leiter, 2023, Progress in cardiovascular diseases.

Position Statement Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Å. Lernmark, G. Bakris, D. Bruns, 2011, Diabetes Care.

The challenge of training pathologists in the 21st century.

B. Smith, D. Sacks, Alan G. Wells, 2006, Human pathology.

IQGAP1 binds AMPK and is required for maximum AMPK activation

D. Sacks, Swetha Parvathaneni, Zhigang Li, 2020, The Journal of biological chemistry.

Inadequate Reporting of Analytical Characteristics of Biomarkers Used in Clinical Research: A Threat to Interpretation and Replication of Study Findings.

D. Bruns, D. Sacks, Zhen Zhao, 2019, Clinical chemistry.

Effect of basic polycations and proteins on purified insulin receptor. Insulin-independent activation of the receptor tyrosine-specific protein kinase by poly(L-lysine).

D. Sacks, J. McDonald, S. Kathuria, 1989, The Biochemical journal.

IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway

D. Matallanas, A. von Kriegsheim, Carolanne Doherty, 2021, Cells.

Evaluation of Three Commercial Automated Assays for the Detection of anti-SARS-CoV-2 Antibodies

A. Remaley, D. Sacks, Roa Harb, 2020, Clinical chemistry.

Glycated protein update: implications of recent studies, including the diabetes control and complications trial.

D. Sacks, R. Benjamin, 1994, Clinical chemistry.

Point of Care Testing in the Diagnosis and Management of Diabetes: A Narrative Update to the National Academy for Clinical Biochemistry Guidelines

S. Sandberg, C. Price, D. Sacks, 2007 .

Establishing Pragmatic Analytical Performance Specifications for Blood Beta-Hydroxybutyrate Testing.

E. Kilpatrick, S. Atkin, D. Sacks, 2023, Clinical chemistry.

The Receptor Protein-tyrosine Phosphatase PTPμ Interacts with IQGAP1*

S. Brady-Kalnay, D. Sacks, T. Gates, 2006, Journal of Biological Chemistry.

Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α*

D. Sacks, Yonghong Zhang, J. Ames, 2017, The Journal of Biological Chemistry.

Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species

A. von Kriegsheim, A. Herrero, P. Crespo, 2023, Science advances.

Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2.

A. Kong, Jung-Hwan Kim, D. Sacks, 2013, Antioxidants & redox signaling.

IQGAP1 binds Rap1 and modulates its activity.

Ha-won Jeong, D. Sacks, Matthew D. Brown, 2007, The Journal of biological chemistry.

Identification and characterization of the Cdc42-binding site of IQGAP1.

R. Frank, D. Sacks, J. Mataraza, 2003, Biochemical and biophysical research communications.

Multiple proteins mediate IQGAP1-stimulated cell migration.

Ha-won Jeong, D. Sacks, J. Mataraza, 2007, Cellular signalling.

The Structural Effects of Endogenous and Exogenous Ca2+/Calmodulin on Phosphorylase Kinase*

D. Sacks, O. Nadeau, G. Carlson, 1997, The Journal of Biological Chemistry.

IQGAP 1 Integrates Ca 2 1 / Calmodulin and Cdc 42 Signaling

D. Sacks, J. Joyal, Y. Ho, 1998 .

Islet autoantibodies and type 1 diabetes: does the evidence support screening?

D. Sacks, B. Calderon, 2014, Clinical chemistry.

Ca2+ signaling and the hippo pathway: Intersections in cellular regulation.

D. Sacks, Louise Thines, Samar Sayedyahossein, 2023, Cellular signalling.

The activity of calmodulin is altered by phosphorylation: modulation of calmodulin function by the site of phosphate incorporation.

D. Sacks, J. Joyal, B. Mazuś, 1995, The Biochemical journal.

Structural Basis for Ca2+-induced Activation and Dimerization of Estrogen Receptor α by Calmodulin*♦

D. Sacks, J. Ames, Zhigang Li, 2012, The Journal of Biological Chemistry.

The Role of Ca2+ and Calmodulin in Estrogen Receptor Function and Tamoxifen Resistance

D. Sacks, 2003 .

The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration

Y. Chien, Ha-won Jeong, D. Sacks, 2009, PLoS pathogens.

Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions

M. S. Kirkman, D. Sacks, Kerry J. Welsh, 2016, Diabetes Care.

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells.

S. Koch, D. Sacks, A. Skerra, 2009, Molecular biology of the cell.

IQGAP1 Protein Binds Human Epidermal Growth Factor Receptor 2 (HER2) and Modulates Trastuzumab Resistance*

D. Dillon, D. Sacks, Colin D. White, 2011, The Journal of Biological Chemistry.

Structural Basis for Ca 2+-Induced Activation and Dimerization of Estrogen Receptor Alpha by Calmodulin

D. Sacks, J. Ames, Zhigang Li, 2019 .

The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.

D. Sacks, Lu Li, Zhigang Li, 2005, The Journal of biological chemistry.