J. Youngren

D. Landau, Y. Segev, R. Rabkin, 2011, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

Joel A. Yates, Christopher K. Wong, M. Gleave, 2022, Nature Communications.

Diet, not aging, causes skeletal muscle insulin resistance.

R. Barnard, J. Youngren, D. Martin, 1995, Gerontology.

Nordihydroguaiaretic acid inhibits insulin‐like growth factor signaling, growth, and survival in human neuroblastoma cells

K. Matthay, W. Weiss, J. Youngren, 2007, Journal of cellular biochemistry.

Clinical and genomic characterization of metastatic small cell/neuroendocrine prostate cancer (SCNC) and intermediate atypical prostate cancer (IAC): Results from the SU2C/PCF/AACRWest Coast Prostate Cancer Dream Team (WCDT).

M. Rubin, M. Gleave, H. Beltran, 2016 .

Dehydroepiandrosterone (DHEA) in metastatic castration-resistant prostate cancer (mCRPC): Preliminary results from the SU2C/PCF/AACR West Coast Dream Team (WCDT).

R. Baertsch, M. Gleave, E. Small, 2016 .

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF‐1 receptor tyrosine kinases, blocks the growth of HER2‐overexpressing human breast cancer cells

P. Kushner, L. Hodges, J. Youngren, 2008, Journal of cellular biochemistry.

Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.

J. Youngren, Marc O. Anderson, C. Berkman, 2007, Bioorganic & medicinal chemistry letters.

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth

S. Schow, J. Youngren, I. Goldfine, 2006, Molecular Cancer Therapeutics.

Nordihydroguaiaretic Acid (NDGA) Inhibits the IGF-1 and c-erbB2/HER2/neu Receptors and Suppresses Growth in Breast Cancer Cells

J. Youngren, I. Goldfine, B. Maddux, 2005, Breast Cancer Research and Treatment.

Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance

Joshua M. Stuart, M. Gleave, F. Feng, 2020, Proceedings of the National Academy of Sciences.

Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

Martin E. Gleave, Colin C. Collins, Brian McConeghy, 2015, Clinical Cancer Research.

DNA Repair Gene Alterations and PARP Inhibitor Response in Patients With Metastatic Castration-Resistant Prostate Cancer.

A. Wyatt, F. Feng, E. Small, 2018, Journal of the National Comprehensive Cancer Network : JNCCN.

Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors.

A. Ashworth, A. Wyatt, S. Tomlins, 2017, Cancer discovery.

Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer

B. Hann, S. Behr, E. Small, 2017, Molecular Cancer Research.

Characterization of neuroendocrine prostate cancer (NEPC) in patients with metastatic castration resistant prostate cancer (mCRPC) resistant to abiraterone (Abi) or enzalutamide (Enz): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).

R. Baertsch, M. Gleave, L. True, 2015 .

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

G. Reaven, A. Grupe, J. Youngren, 1995, Nature.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Joshua M. Stuart, Donavan T. Cheng, Luke A. Gilbert, 2018, Cell.

The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities.

D. Accili, G. Reaven, R. Vigneri, 2008, Endocrine reviews.

Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase

J. Youngren, 2008 .

Effective treatments for insulin resistance: trim the fat and douse the fire

Joseph L Evans, J. Youngren, I. Goldfine, 2004, Trends in Endocrinology & Metabolism.

Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039))

Joshua M. Stuart, Donavan T. Cheng, Luke A. Gilbert, 2018 .

CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield.

E. Small, Jiaoti Huang, T. Link, 2017, Journal of vascular and interventional radiology : JVIR.

Androgen receptor (AR) amplification in patients with metastatic castration-resistant prostate cancer (mCRPC) refractory to therapy with abiraterone acetate or enzalutamide: Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).

M. Gleave, E. Small, J. Youngren, 2014 .

Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team.

Joshua M. Stuart, M. Gleave, E. Small, 2016, European urology focus.

Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia.

D. Accili, O. McGuinness, J. Youngren, 2006, American journal of physiology. Endocrinology and metabolism.

Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

J. Youngren, I. Goldfine, F. Schaufele, 2014, PloS one.

Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling.

B. Kahn, Young-Bum Kim, J. Youngren, 2005, American journal of physiology. Endocrinology and metabolism.

Regulation of insulin receptor function

J. Youngren, 2007, Cellular and Molecular Life Sciences.

Membrane glycoprotein PC-1 and insulin resistance

G. Dohm, J. Youngren, I. Goldfine, 1998, Molecular and Cellular Biochemistry.

Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T.

Xiaojuan Li, S. Majumdar, M. Schambelan, 2008, Magnetic resonance imaging.

Contributions of the American Journal of Physiology to the discovery of insulin.

J. Youngren, I. Goldfine, 1998, The American journal of physiology.

Persistence of AR signaling in small cell neuroendocrine prostate cancer (SCNC) and intermediate atypical carcinoma (IAC): Results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).

Joshua M. Stuart, M. Gleave, T. Goldstein, 2016 .

Insulin receptor autophosphorylation in cultured myoblasts correlates to glucose disposal in Pima Indians.

R. Pratley, J. Youngren, I. Goldfine, 1999, American journal of physiology. Endocrinology and metabolism.

Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer

E. Small, J. Youngren, G. Thomas, 2017, Oncotarget.

Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.

R. Terkeltaub, D. Accili, Kristen Johnson, 2005, Diabetes.

PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity

R. Vigneri, J. Youngren, I. Goldfine, 1996, Diabetologia.

Effects of acute and chronic exercise on skeletal muscle glucose transport in aged rats.

R. Barnard, J. Youngren, 1994, Journal of applied physiology.

Impaired insulin-receptor autophosphorylation is an early defect in fat-fed, insulin-resistant rats.

R. Barnard, J. Youngren, J. Paik, 2001, Journal of applied physiology.

Parallel synthesis of diarylureas and their evaluation as inhibitors of insulin-like growth factor receptor.

R. Guy, J. Youngren, I. Goldfine, 2006, Journal of combinatorial chemistry.

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle

Xiaojuan Li, M. Schambelan, U. Masharani, 2011, PloS one.

Effects of Controlled-Release Alpha Lipoic Acid in Lean, Nondiabetic Patients with Polycystic Ovary Syndrome

Joseph L Evans, U. Masharani, J. Youngren, 2010, Journal of diabetes science and technology.

Role of PC‐1 in The Etiology of Insulin Resistance

J. Youngren, I. Goldfine, B. Maddux, 1999, Annals of the New York Academy of Sciences.

The molecular and pathway characterization of patients with metastatic castration resistant prostate cancer (mCRPC) refractory to therapy with abiraterone acetate or enzalutamide: Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).

Joshua M. Stuart, M. Gleave, E. Small, 2014 .

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

D. Berry, S. Cummings, E. Fung, 2020, Annals of oncology : official journal of the European Society for Medical Oncology.

Influence of gender on the relationship between insulin sensitivity, adiposity, and plasma lipids in lean nondiabetic subjects.

U. Masharani, J. Youngren, I. Goldfine, 2009, Metabolism: clinical and experimental.

S-4: Insulin receptor inhibitors as a cause of insulin resistance

G. Dohm, J. Youngren, I. Goldfine, 2009 .

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

G. Dohm, J. Youngren, I. Goldfine, 1996, Diabetes.

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.

Joshua M. Stuart, Christopher K. Wong, M. Rubin, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.