H. Hirai

发表

Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling.

H. Ishihara, T. Sasaoka, H. Hori, 1999, Biochemical and biophysical research communications.

p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts.

T. Nakamoto, H. Hirai, H. Hirai, 1999, Biochemical and biophysical research communications.

Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation.

M. Yoshida, J. Inoue, H. Hirai, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Activation of pp60 c-src Depending on Cell Density in PC12h Cells*

M. Okada, T. Nakamoto, H. Hirai, 1997, The Journal of Biological Chemistry.

HTLV-I encoded Tax in association with NF-kappa B precursor p105 enhances nuclear localization of NF-kappa B p50 and p65 in transfected cells.

K. Arai, M. Muramatsu, M. Yoshida, 1993, Oncogene.

Trans-activator Tax of human T-cell leukemia virus type 1 enhances mutation frequency of the cellular genome.

M. Yoshida, H. Hirai, T. Suzuki, 1999, Virology.

Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas.

Y. Yazaki, S. Aizawa, C. Morimoto, 1996, Biochemical and biophysical research communications.

Ornithine decarboxylase- and ras-induced cell transformations: reversal by protein tyrosine kinase inhibitors and role of pp130CAS

L. Andersson, A. Paasinen-Sohns, E. Hölttä, 1995, Molecular and cellular biology.

A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.

M. Yoshida, J. Fujisawa, H. Hirai, 1993, Oncogene.

Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.

H. Ishihara, T. Sasaoka, H. Hori, 2001, Endocrinology.

Intracellular signalling pathways of okadaic acid leading to mitogenesis in Rat1 fibroblast overexpressing insulin receptors: okadaic acid regulates Shc phosphorylation by mechanisms independent of insulin.

H. Ishihara, T. Sasaoka, T. Wada, 1999, Cellular signalling.

Involvement of cell cycle progression in survival signaling through CD40 in the B-lymphocyte line WEHI-231

T. Adachi, T. Tsubata, H. Hirai, 2004, Cell Death and Differentiation.

Integrin‐mediated signal transduction in cells lacking focal adhesion kinase p125FAK

S. Aizawa, T. Nakamoto, Terukatsu Sasaki, 1998, FEBS letters.

Nephrotic syndrome developed in a patient with acute promyelocytic leukemia treated with daunomycin.

Y. Yazaki, T. Nakamoto, H. Hirai, 1995, Nephron.

In vitro transcription of the hepatitis B virus gene by nuclear extracts of human hepatoma cells.

A. Nishizono, H. Hirai, T. Shikata, 1991, Virology.

Tyrosine phosphorylation of vav protooncogene product in primary human myelogenous leukemic cells stimulated by granulocyte colony-stimulating factor.

A. Yuo, H. Hirai, Y. Hanazono, 1995, Biochemical and biophysical research communications.

Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105.

M. Muramatsu, M. Yoshida, J. Fujisawa, 1992, Oncogene.

Tyrosine phosphorylation of p130Cas in cell adhesion and transformation.

Y. Yazaki, T. Nakamoto, H. Hirai, 1996, Human Cell.

Ligation of the T cell antigen receptor induces tyrosine phosphorylation of p105CasL, a member of the p130Cas‐related docking protein family, and its subsequent binding to the Src homology 2 domain of c‐Crk

Y. Yazaki, C. Morimoto, T. Nakamoto, 1997, European journal of immunology.

Biochemical analysis of p120/130: a protein-tyrosine kinase substrate restricted to T and myeloid cells.

C. Rudd, H. Hirai, A. Bouton, 1997, Journal of immunology.

Activation of the long terminal repeat of human endogenous retrovirus K by melanoma-specific transcription factor MITF-M.

Kunihiko Hashimoto, I. Katoh, H. Hirai, 2011, Neoplasia.

HTLV-1 oncoprotein tax and cellular transcription factors.

M. Yoshida, J. Fujisawa, H. Hirai, 1995, Current topics in microbiology and immunology.

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

E. Ruoslahti, S. Aizawa, K. Vuori, 1996, Molecular and cellular biology.

TrkB-T1 regulates the RhoA signaling and actin cytoskeleton in glioma cells.

M. Hayashi, H. Hirai, K. Ohira, 2006, Biochemical and biophysical research communications.

A Truncated Tropo-Myosine-Related Kinase B Receptor, T1, Regulates Glial Cell Morphology via Rho GDP Dissociation Inhibitor 1

M. Hayashi, H. Hirai, Y. Sahara, 2005, The Journal of Neuroscience.

Tax protein of HTLV-1 destabilizes the complexes of NF-kappa B and I kappa B-alpha and induces nuclear translocation of NF-kappa B for transcriptional activation.

M. Yoshida, H. Hirai, H. Hirai, 1995, Oncogene.

Tax protein of HTLV-1 interacts with the Rel homology domain of NF-kappa B p65 and c-Rel proteins bound to the NF-kappa B binding site and activates transcription.

M. Yoshida, H. Hirai, T. Suzuki, 1994, Oncogene.

HTLV-1 Tax enhances NF-kappa B2 expression and binds to the products p52 and p100, but does not suppress the inhibitory function of p100.

M. Yoshida, J. Fujisawa, H. Hirai, 1995, Virology.

Increased Tyrosine-Phosphorylation of 55-kDa Proteins in -Actin/ Tec Transgenic Mice

M. Katsuki, Y. Yazaki, H. Mano, 1995 .