A. Kanatsuka

发表

Mitogen-activated protein kinase and p70 ribosomal protein S6 kinase are not involved in the insulin-dependent stimulation of cAMP phosphodiesterase kinase in rat adipocytes.

H. Onuma, H. Makino, H. Osawa, 1998, Biochimica et biophysica acta.

Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.

J. Miyazaki, H. Makino, A. Kanatsuka, 1997, Metabolism: clinical and experimental.

A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro

S. Takasawa, H. Okamoto, H. Makino, 1998, Diabetologia.

Increased activity and expression of MAP kinase in HCC model rats induced by 3'-methyl-4-dimethylamino-azobenzene.

O. Yokosuka, B. Goldstein, Y. Suzuki, 1999, Journal of hepatology.

Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus.

I. Takei, A. Kanatsuka, N. Harii, 2008, The Journal of clinical endocrinology and metabolism.

Uniformity in clinical and HLA-DR status regardless of age and gender within fulminant type 1 diabetes.

A. Imagawa, T. Hanafusa, H. Makino, 2008, Diabetes research and clinical practice.

Clinical and immunogenetic characteristics of fulminant type 1 diabetes associated with pregnancy.

T. Kobayashi, A. Imagawa, T. Hanafusa, 2005, The Journal of clinical endocrinology and metabolism.

Fulminant type 1 diabetes as a high risk group for diabetic microangiopathy—a nationwide 5-year-study in Japan

T. Kobayashi, A. Imagawa, T. Hanafusa, 2007, Diabetologia.

Actual usage and clinical effectiveness of insulin preparations in patients with Type 1 diabetes mellitus in Japan: CoDiC-based analysis of clinical data obtained at multiple institutions (JDDM 3).

A. Kanatsuka, K. Hirao, Masashi Kobayashi, 2006, Diabetes research and clinical practice.

Different contribution of class II HLA in fulminant and typical autoimmune type 1 diabetes mellitus

T. Kobayashi, A. Imagawa, T. Hanafusa, 2005, Diabetologia.

Secretion of islet amyloid polypeptide in response to glucose

H. Makino, A. Kanatsuka, T. Yamaguchi, 1989, FEBS letters.

Effect of calcium on the secretion of somatostatin and insulin from pancreatic islets.

H. Makino, A. Kanatsuka, Y. Matsushima, 1981, Endocrinology.

Patient characteristics associated with improvement in glycemic control following addition of an oral antidiabetic drug to DPP-4 inhibitor monotherapy in Japanese patients with type 2 diabetes mellitus (JDDM 60)

H. Maegawa, K. Yamazaki, A. Kanatsuka, 2021, Diabetology International.

Relationship between kidney function decline and initial risk factors for the progression of diabetic kidney disease: a retrospective analysis of 91 Japanese patients with type 2 diabetes

A. Kanatsuka, Y. Tokuyama, T. Ishizuka, 2016, Diabetology International.

Effect of ACE gene on diabetic nephropathy in NIDDM patients with insulin resistance.

H. Makino, A. Kanatsuka, Y. Saito, 1999, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Multicenter Prevention Trial of Slowly Progressive Type 1 Diabetes with Small Dose of Insulin (the Tokyo Study)

I. Takei, A. Kanatsuka, T. Maruyama, 2003, Annals of the New York Academy of Sciences.

Insulin Intervention to Preserve β Cells in Slowly Progressive Insulin‐Dependent (Type 1) Diabetes Mellitus a

I. Takei, A. Kanatsuka, T. Maruyama, 2002, Annals of the New York Academy of Sciences.

Association of a SNP in the IAPP gene and hyperglycemia on β-cell dysfunction in type 2 diabetes: the Toon Genome Study

Y. Tabara, H. Makino, H. Osawa, 2021, Diabetology International.

Frequency of the G/G Genotype of Resistin Single Nucleotide Polymorphism at −420 Appears to Be Increased in Younger-Onset Type 2 Diabetes

M. Kasuga, Y. Tabara, T. Miki, 2007, Diabetes.

Combination of disease duration‐to‐age at diagnosis and hemoglobin A1c‐to‐serum C‐peptide reactivity ratios predicts patient response to glucose‐lowering medication in type 2 diabetes: A retrospective cohort study across Japan (JDDM59)

H. Maegawa, A. Kanatsuka, Yasunori Sato, 2021, Journal of diabetes investigation.

The initiation of insulin therapy in type 2 diabetic patients treated with oral anti-diabetic drugs: an observational study in multiple institutes across Japan (JDDM27)

H. Yokoyama, A. Kanatsuka, K. Hirao, 2012, Diabetology International.

Insulin-sensitive phosphodiesterase and insulin receptor binding in fat cells from spontaneously obese rats

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Diabetologia.

Effect of somatomedin C on insulin-sensitive phosphodiesterase in rat fat cells.

H. Makino, A. Kanatsuka, S. Yoshida, 1988, Metabolism: clinical and experimental.

Effects of diet restriction on insulin-sensitive phosphodiesterase in rat fat cells.

H. Makino, A. Kanatsuka, S. Yoshida, 1987, Metabolism: clinical and experimental.

Insulin Resistance of Fat Cells from Spontaneously Diabetic KK Mice: Analysis of Insulin-sensitive Phosphodiesterase

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Diabetes.

Activation of insulin-sensitive phosphodiesterase by lectins and insulin-dextran complex in rat fat cells.

H. Makino, A. Kanatsuka, Y. Sakamoto, 1984, Metabolism: clinical and experimental.

Effects of changes in serum insulin in response to dexamethasone and adrenalectomy on insulin-sensitive phosphodiesterase in rat fat cells.

H. Makino, A. Kanatsuka, S. Yoshida, 1984, Metabolism: clinical and experimental.

Increased sensitivity of insulin-sensitive phosphodiesterase to insulin in fat cells from streptozotocin diabetic rats.

H. Makino, A. Kanatsuka, M. Osegawa, 1983, Endocrinology.

Hypotonic activation of insulin-sensitive phosphodiesterase in rat fat cells

H. Makino, A. Kanatsuka, M. Osegawa, 1982, Molecular and Cellular Endocrinology.

Effects of dithiothreitol on insulin-sensitive phosphodiesterase in rat fat cells.

H. Makino, A. Kanatsuka, M. Osegawa, 1982, Biochimica et biophysica acta.

Effects of sulfonylureas on membrane-bound low Km cyclic AMP phosphodiesterase in rat fat cells.

H. Makino, A. Kanatsuka, M. Osegawa, 1982, Biochimica et biophysica acta.

Activation of membrane-bound low Km cyclic AMP phosphodiesterase by tolbutamide in fat cells

H. Makino, A. Kanatsuka, M. Osegawa, 1981 .

Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor.

Y. Ebina, H. Makino, Y. Suzuki, 1989, Science.

Fulminant type 1 diabetes: a nationwide survey in Japan.

A. Imagawa, T. Hanafusa, H. Makino, 2003, Diabetes care.

Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia.

H. Makino, A. Kanatsuka, M. Mimura, 1992, Metabolism: clinical and experimental.

Nationwide survey to compare the prevalence of transient elevation of liver transaminase during treatment of diabetic ketosis or ketoacidosis in new-onset acute and fulminant type 1 diabetes mellitus

Y. Iwamoto, A. Imagawa, T. Hanafusa, 2008, Annals of medicine.

Different contribution of class II HLA in fulminant and typical autoimmune type 1 diabetes mellitus

T. Kobayashi, A. Imagawa, T. Hanafusa, 2007, Diabetologia.

First-phase insulin response to glucose in nonobese or obese subjects with glucose intolerance: analysis by C-peptide secretion rate.

H. Makino, M. Taira, A. Kanatsuka, 1988, Metabolism: clinical and experimental.

Hypersecretion of IAPP from the islets of VMH-lesioned rats and obese Zucker rats.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1992, Diabetes research and clinical practice.

Hypersecretion of islet amyloid polypeptide from pancreatic islets of ventromedial hypothalamic-lesioned rats and obese Zucker rats.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1991, Endocrinology.

Continuous Subcutaneous Insulin Infusion

A. Kanatsuka, H. Ito, 1998, Diabetes Care.

Trends in glycemic control in patients with insulin therapy compared with non-insulin or no drugs in type 2 diabetes in Japan: a long-term view of real-world treatment between 2002 and 2018 (JDDM 66)

H. Yokoyama, H. Maegawa, K. Yamazaki, 2022, BMJ Open Diabetes Research & Care.

Biphasic insulin response to high glucose and a role of protons and calcium.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1987, Endocrinology.

Islet amyliod polypeptide-derived amyloid deposition increases along with the duration of type 2 diabetes mellitus

H. Makino, A. Kanatsuka, A. Mikata, 1992 .

An Assessment of the New NIH Diagnostic Criteria for Diabetes Mellitus According to Insulin Response in a 75 g Oral Glucose Tolerance Test and Levels of Hemoglobin AIC

H. Makino, A. Kanatsuka, N. Hashimoto, 1982, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects

G. Bell, H. Makino, A. Kanatsuka, 1995, Diabetologia.

Abnormal calcium handling by perifused pancreatic islets from neonatal streptozotocin diabetic model rats.

H. Makino, A. Kanatsuka, H. Horie, 1987, Metabolism: clinical and experimental.

Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family

S. Seino, G. Bell, H. Makino, 1993, Diabetologia.

Analysis of the insulin-sensitive phosphodiesterase 3B gene in type 2 diabetes.

H. Makino, Y. Suzuki, M. Taira, 2001, Diabetes research and clinical practice.

Detection of an amino acid polymorphism in hormone-sensitive lipase in Japanese subjects.

H. Makino, M. Taira, A. Kanatsuka, 1996, Metabolism: clinical and experimental.

Effect of glucose on somatostatin secretion from isolated pancreatic islets of normal and streptozotocin-diabetic rats.

H. Makino, A. Kanatsuka, Y. Matsushima, 1981, Endocrinology.

Mutations in the hepatocyte nuclear factor-4alpha gene in Japanese with non-insulin-dependent diabetes: a nucleotide substitution in the polypyrimidine tract of intron 1b.

T. Egashira, H. Makino, Y. Suzuki, 2000, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Is Somatostatin a True Local Inhibitory Regulator of Insulin Secretion?

H. Makino, A. Kanatsuka, H. Horie, 1984, Diabetes.

Effect of hypophysectomy and growth hormone administration on somatostatin and gastrin content in the stomach of rats.

H. Makino, A. Kanatsuka, Y. Matsushima, 1981, Endocrinologia japonica.

Islet amyloid polypeptide gene: no evidence of abnormal promoter region in thirty-five type 2 diabetic patients.

H. Makino, M. Taira, A. Kanatsuka, 1994, Diabetes research and clinical practice.

Effect of streptozotocin administration on somatostatin content of pancreas and hypothalamus in rats.

H. Makino, A. Kanatsuka, Y. Matsushima, 1977, Endocrinologia japonica.

Immunohistochemical changes of somatostatin cells in the pancreatic islets of rats after streptozotocin administration.

H. Makino, A. Kanatsuka, Y. Matsushima, 1978, Endocrinologia japonica.

Changes in pancreatic somatostatin content in spontaneously diabetic mice, as determined by radioimmunoassay and immunohistochemical methods.

H. Makino, A. Kanatsuka, Y. Matsushima, 1979, Endocrinology.

Effect of caerulein administration on portal plasma somatostatin in dogs

A. Kanatsuka, S. Fujimoto, J. Kasanuki, 1984, Gastroenterologia Japonica.

Pancreatic somatostatin contents in spontaneously diabetic KK and non-obese diabetic (NOD) mice.

H. Makino, A. Kanatsuka, Y. Tochino, 1982, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Effect of hypophysectomy and growth hormone administration on somatostatin content in the rat hypothalamus.

H. Makino, A. Kanatsuka, Y. Matsushima, 1979, Neuroendocrinology.

Continuous Subcutaneous Insulin Infusion

A. Kanatsuka, Haruo Ito, 1992, Diabetes Care.

Islet amyloid polypeptide/amylin contents in pancreata increase in genetically obese and diabetic mice.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1993, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus.

Toru Egashira, A. Kanatsuka, Y. Tokuyama, 2006, Metabolism: clinical and experimental.

Islet Amyloid Polypeptide/Amylin in Pancreatic β-Cell Line Derived From Transgenic Mouse Insulinoma

J. Miyazaki, K. Yamamura, H. Makino, 1992, Diabetes.

Dual mechanism involved in the hydrolysis of polyphosphoinositides in rat pancreatic islets.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1989, Endocrinology.

Effects of monensin on glucose-induced insulin release and 45Ca2+ outflow.

H. Makino, A. Kanatsuka, N. Hashimoto, 1986, Advances in experimental medicine and biology.

Efficacy and safety of the dipeptidyl peptidase‐4 inhibitor sitagliptin compared with α‐glucosidase inhibitor in Japanese patients with type 2 diabetes inadequately controlled on sulfonylurea alone (SUCCESS‐2): a multicenter, randomized, open‐label, non‐inferiority trial

A. Kanatsuka, K. Sakurai, M. Takemoto, 2014, Diabetes, obesity & metabolism.

Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic beta cells.

J. Miyazaki, H. Makino, Y. Suzuki, 1999, Metabolism: clinical and experimental.

Lactic acidosis and hypoglycemia associated with acute leukemia.

H. Makino, A. Kanatsuka, H. Horie, 1985, Japanese journal of medicine.

Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin.

J. Miyazaki, K. Yamamura, A. Kanatsuka, 1995, European journal of endocrinology.

A patient with subcutaneous-insulin resistance treated by insulin lispro plus heparin.

A. Kanatsuka, Y. Tokuyama, O. Nozaki, 2001, Diabetes research and clinical practice.

Augmented gastrin responses in diabetic patients with vagal neuropathy

H. Makino, A. Kanatsuka, N. Hashimoto, 1984, Diabetologia.

Insulin-sensitive phosphodiesterase in fat cells from human subcutaneous adipose tissue.

H. Makino, A. Kanatsuka, S. Fujimoto, 1987, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Self-reported rate of eating is significantly associated with body mass index in Japanese patients with type 2 diabetes. Japan Diabetes Clinical Data Management Study Group (JDDM26)

H. Yokoyama, Koichi Iwasaki, H. Sone, 2012, Appetite.

Islet amyloid polypeptide inhibits glucose-stimulated insulin secretion from isolated rat pancreatic islets.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1989, Biochemical and biophysical research communications.

Somatostatin and insulin secretion from pancreatic islets: studies on the effect of high K+, 9-aminoacridine and valinomycin.

H. Makino, A. Kanatsuka, J. Kasanuki, 1983, Metabolism: clinical and experimental.

Beta-cell dysfunction in late-onset diabetic subjects carrying homozygous mutation in transcription factors NeuroD1 and Pax4.

T. Egashira, A. Kanatsuka, Y. Tokuyama, 2002, Metabolism: clinical and experimental.

Serum resistin level is associated with insulin sensitivity in Japanese patients with type 2 diabetes mellitus.

Toru Egashira, H. Onuma, H. Makino, 2007, Metabolism: clinical and experimental.

Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic β cells

J. Miyazaki, H. Makino, A. Kanatsuka, 1999 .

Molecular cloning of rat Pax4: identification of four isoforms in rat insulinoma cells.

A. Kanatsuka, Y. Saito, K. Sakurai, 1998, Biochemical and biophysical research communications.

Changes in oral antidiabetic prescriptions and improved glycemic control during the years 2002–2011 in Japan (JDDM32)

K. Yamazaki, A. Kashiwagi, A. Kanatsuka, 2013, Journal of diabetes investigation.

Clinical features of diabetes mellitus with the mitochondrial DNA 3243 (A-G) mutation in Japanese: maternal inheritance and mitochondria-related complications.

Yutaka Seino, Takashi Kadowaki, Masashi Kobayashi, 2003, Diabetes research and clinical practice.

Reduction of Erythrocyte (Na+-K+)ATPase Activity in Type 2 (Non-Insulin-Dependent) Diabetic Patients with Microalbuminuria

H. Makino, A. Kanatsuka, M. Mimura, 1994, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

The status of diabetes control and antidiabetic drug therapy in Japan--a cross-sectional survey of 17,000 patients with diabetes mellitus (JDDM 1).

K. Yamazaki, A. Kanatsuka, Masashi Kobayashi, 2006, Diabetes research and clinical practice.

The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.

Kazuya Yamada, H. Onuma, H. Makino, 2004, American journal of human genetics.

Five missense mutations in glucagon-like peptide 1 receptor gene in Japanese population.

Toru Egashira, A. Kanatsuka, Y. Tokuyama, 2004, Diabetes research and clinical practice.

Relationship between the efficacy of oral antidiabetic drugs and clinical features in type 2 diabetic patients (JDDM38)

Kokichi Tanaka, O. Tomonaga, Y. Kurihara, 2015, Journal of diabetes investigation.

Evaluation of insulin regimens as an effective option for glycemic control in patients with type 2 diabetes: A propensity score‐matched cohort study across Japan (JDDM31)

A. Kashiwagi, A. Kanatsuka, Yasunori Sato, 2014, Journal of diabetes investigation.

Islet amyloid polypeptide and its N-terminal and C-terminal flanking peptides' immunoreactivity in islet amyloid of diabetic patients.

H. Makino, M. Taira, A. Kanatsuka, 1994, Diabetes research and clinical practice.

Improved insulin sensitivity with sodium-glucose cotransporter 2 inhibitor treatment in a patient with slowly progressive type 1 diabetes mellitus with metabolic syndrome: a case report

A. Kanatsuka, Y. Tokuyama, T. Ishizuka, 2020, Diabetology International.

Effects of weight loss in obese subjects with normal fasting plasma glucose or impaired glucose tolerance on insulin release and insulin resistance according to a minimal model analysis.

A. Kanatsuka, K. Yagui, H. Bujo, 2004, Metabolism: clinical and experimental.

Islet amyloid polypeptide/amylin contents in pancreas change with increasing age in genetically obese and diabetic mice.

H. Makino, A. Kanatsuka, Y. Saito, 1996, Diabetes research and clinical practice.

Pathophysiologic phenotypes of Japanese subjects with varying degrees of glucose tolerance: using the combination of C-peptide secretion rate and minimal model analysis.

A. Kanatsuka, Y. Saito, K. Sakurai, 2001, Metabolism: clinical and experimental.

IAPP/amylin and β-cell failure: implication of the risk factors of type 2 diabetes

H. Makino, A. Kanatsuka, S. Kou, 2018, Diabetology International.

Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor

Y. Ebina, H. Makino, Y. Suzuki, 1989 .

Islet amyloid polypeptide-derived amyloid deposition increases along with the duration of type 2 diabetes mellitus.

H. Makino, A. Kanatsuka, A. Mikata, 1992, Diabetes research and clinical practice.

Relation between glucose-stimulated insulin secretion and intracellular calcium accumulation studied with a superfusion system of a glucose-responsive pancreatic beta-cell line MIN6.

J. Miyazaki, K. Yamamura, M. Kikuchi, 1993, Endocrinology.

The Dipeptidyl Peptidase-4 Inhibitor Vildagliptin has the Capacity to Repair β-Cell Dysfunction and Insulin Resistance

Y. Suzuki, A. Kanatsuka, M. Sunaga, 2014, Hormone and Metabolic Research.

Erratum to: The initiation of insulin therapy in type 2 diabetic patients treated with oral anti-diabetic drugs: an observational study in multiple institutes across Japan (JDDM27)

H. Yokoyama, A. Kanatsuka, K. Hirao, 2012, Diabetology International.

Fulminant type 1 diabetes: a nationwide survey in Japan.

A. Imagawa, T. Hanafusa, H. Makino, 2003, Diabetes care.

[Construction of transgenic mouse system expressing human islet amyloid polypeptide (IAPP)/amylin].

H. Makino, A. Kanatsuka, K. Yagui, 1994, Nihon rinsho. Japanese journal of clinical medicine.

Mechanisms Involved in the Depleting Effect of Cysteamine on Pancreatic Somatostatin

H. Makino, A. Kanatsuka, N. Hashimoto, 1987, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Modulation of Insulin Action by Fasting: A Study Using a Phosphodiesterase Activation System in Rat Fat Cells

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus.

I. Takei, A. Kanatsuka, N. Harii, 2008, The Journal of clinical endocrinology and metabolism.