L. Bale

发表

Insulin-like growth factor I induction of c-myc expression in bovine fibroblasts can be blocked by antecedent insulin receptor activation.

C. Conover, L. Bale, 1998, Experimental cell research.

Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth factor action.

C. Conover, L. Bale, J. Clarkson, 1996, Endocrinology.

Constitutive expression of pregnancy-associated plasma protein-A in arterial smooth muscle reduces the vascular response to injury in vivo.

C. Conover, M. Overgaard, L. Bale, 2013, American journal of physiology. Endocrinology and metabolism.

Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-A.

C. Conover, L. Bale, K. Keenan, 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

Pregnancy‐associated plasma protein‐A (PAPP‐A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis

C. Conover, C. Oxvig, E. Atkinson, 2022, Journal of cellular physiology.

Characterization of mouse pericardial fat: regulation by PAPP-A.

C. Conover, L. Bale, Sally A. West, 2018, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.

C. Conover, D. Powell, L. Bale, 2011, Endocrinology.

Physiological Concentrations of Insulin Induce Cellular Desensitization to the Mitogenic Effects of Insulin-Like Growth Factor I

C. Conover, L. Bale, J. Clarkson, 1994, Diabetes.

Disruption of insulin-like growth factor-II imprinting during embryonic development rescues the dwarf phenotype of mice null for pregnancy-associated plasma protein-A.

C. Conover, L. Bale, 2005, The Journal of endocrinology.

Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development

E. Füchtbauer, C. Conover, M. Overgaard, 2004, Development.

Resistance to age-dependent thymic atrophy in long-lived mice that are deficient in pregnancy-associated plasma protein A

C. Conover, L. Bale, A. Vallejo, 2009, Proceedings of the National Academy of Sciences.

Genetic and Pharmacological Inhibition of PAPP-A Protects Against Visceral Obesity in Mice.

C. Conover, L. Bale, Akhila Ramakrishna, 2020, Endocrinology.

Cellular actions of insulin-like growth factor binding protein-3.

C. Conover, S. Durham, L. Bale, 1993, Advances in experimental medicine and biology.

Regulation of insulin-like growth factor binding protein-3 messenger ribonucleic acid expression by insulin-like growth factor I.

C. Conover, L. Bale, 1992, Endocrinology.

Cholestyramine treatment in early life of low-density lipoprotein receptor deficient Watanabe rabbits: decreased aortic cholesteryl ester accumulation and atherosclerosis in adult life.

Z. Rymaszewski, L. Bale, M. Subbiah, 1987, Biochimica et biophysica acta.

Insulin-like growth factor-II enhancement of human fibroblast growth via a nonreceptor-mediated mechanism.

C. Conover, L. Bale, J. Clarkson, 1994, Endocrinology.

Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A

A. Oberg, C. Conover, S. Weroha, 2018, PloS one.

Effect of glucocorticoid on insulin-like growth factor (IGF) regulation of IGF-binding protein expression in fibroblasts.

C. Conover, L. Bale, J. Clarkson, 1995, Endocrinology.

Effect of enhancement of cholesterol degradation during neonatal life of guinea pig on its subsequent response to dietary cholesterol.

L. Bale, M. Subbiah, J. Li, 1979, Atherosclerosis.

Insulin-like growth factor (IGF) binding protein-3 potentiation of IGF action is mediated through the phosphatidylinositol-3-kinase pathway and is associated with alteration in protein kinase B/AKT sensitivity.

C. Conover, D. Powell, S. Durham, 2000, Endocrinology.

Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice.

C. Conover, M. Overgaard, C. Oxvig, 2013, Endocrinology.

Regulation of insulin-like growth factor binding protein-5 messenger ribonucleic acid expression and protein availability in rat osteoblast-like cells.

O. Tørring, C. Conover, L. Bale, 1993, Endocrinology.

C. Conover, D. Powell, S. Durham, 2000, Endocrinology.

Transforming Growth Factor‐β Regulation of the Insulin‐Like Growth Factor Binding Protein‐4 Protease System in Cultured Human Osteoblasts

C. Conover, M. Overgaard, C. Oxvig, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effect of neonatal modulation of cholesterol homeostasis on subsequent response to cholesterol challenge in adult guinea pig.

L. Bale, B. Kottke, J. Li, 1980, The Journal of clinical investigation.

Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice

K. Nair, C. Conover, L. Bale, 2016, Experimental Gerontology.

Identification and Regulation of the IGFBP-4 Protease and Its Physiological Inhibitor in Human Trophoblasts and Endometrial Stroma : Evidence for Paracrine Regulation of IGF-II Bioavailability in the Placental Bed during Human Implantation

L. Giudice, C. Conover, M. Overgaard, 2002 .

Regional differences in cholesterol content of aorta in response to experimental coarctation in spontaneously atherosclerosis-susceptible pigeons

L. Bale, I. Kottke, C. Grabau, 1980, Basic Research in Cardiology.

PAPP-A in normal human mesangial cells: effect of inflammation and factors related to diabetic nephropathy.

C. Conover, L. Bale, D. Donegan, 2016, The Journal of endocrinology.

Human hepatoma cells synthesize and secrete insulin-like growth factor Ia prohormone under growth hormone control

C. Conover, L. Bale, F. Liu, 1993, Regulatory Peptides.

Molecular regulation of the IGF-binding protein-4 protease system in human fibroblasts: identification of a novel inducible inhibitor.

C. Conover, M. Overgaard, M. Christiansen, 2002, Endocrinology.

Transforming growth factor-b 1 modulates insulin-like growth factor binding protein-4 expression and proteolysis in cultured periosteal explants

Joseph H. Schwab, C. Conover, L. Bale, 2010 .

Phorbol ester tumor promoters regulate insulin-like growth factor-binding protein-4 proteolysis.

C. Conover, L. Bale, J. Clarkson, 1993, Endocrinology.

Human breast milk stimulates low density lipoprotein (LDL) binding to human skin fibroblasts in culture.

L. Bale, M. Subbiah, B. Kottke, 1985, Biochemical and biophysical research communications.

Inducible knockdown of pregnancy‐associated plasma protein‐A gene expression in adult female mice extends life span

C. Conover, L. Bale, Sally A. West, 2017, Aging cell.

Loss of pregnancy‐associated plasma protein A extends lifespan in mice

C. Conover, L. Bale, Cheryl A Conover, 2007, Aging cell.

Characterization and partial purification of the insulin-like growth factor (IGF)-dependent IGF binding protein-4-specific protease from human fibroblast conditioned media.

C. Conover, L. Bale, T. Haddad, 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

A Novel Neutralizing Antibody Targeting Pregnancy-Associated Plasma Protein-A Inhibits Ovarian Cancer Growth and Ascites Accumulation in Patient Mouse Tumorgrafts

C. Conover, C. Oxvig, P. Haluska, 2015, Molecular Cancer Therapeutics.

Longevity is not influenced by prenatal programming of body size

C. Conover, L. Bale, M. A. Mason, 2010, Aging cell.

Regional aortic differences in atherosclerosis-susceptibility: Changes in prostaglandin biosynthesis and cholesterol accumulation in response to desoxycorticosterone (DOCA)-salt induced hypertension

L. Bale, M. Subbiah, B. Kottke, 1981, Virchows Archiv. B, Cell pathology including molecular pathology.

Bile acid and cholesterol excretion in the pregnant guinea pig: Studies on the hypercholesterolemia of pregnancy

L. Bale, M. Subbiah, Job R. Li, 1978, Steroids.

Pregnancy-associated plasma protein a gene expression as a target of inflammatory cytokines.

C. Conover, M. Overgaard, C. Oxvig, 2004, Endocrinology.

Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development.

M. Nyegaard, C. Conover, M. Overgaard, 2010, American journal of physiology. Heart and circulatory physiology.

Functional insulin receptors on human epithelial ovarian carcinoma cells: implications for IGF-II mitogenic signaling.

C. Conover, P. Roche, L. Bale, 2002, Endocrinology.

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.

C. Conover, C. Oxvig, V. Torres, 2020, JCI insight.

Inducible reduction in pregnancy-associated plasma protein-A gene expression inhibits established atherosclerotic plaque progression in mice.

C. Conover, L. Bale, Suban S Chakraborty, 2014, Endocrinology.

Senescence induces proteolytically-active PAPP-A secretion and association with extracellular vesicles in human pre-adipocytes

C. Conover, L. Bale, 2022, Experimental Gerontology.

Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts.

C. Conover, C. Oxvig, L. Bale, 2006, Endocrinology.

Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.

C. Conover, M. Overgaard, C. Oxvig, 2006, American journal of physiology. Cell physiology.

Surface association of pregnancy-associated plasma protein-A accounts for its colocalization with activated macrophages.

C. Conover, C. Oxvig, L. Bale, 2007, American journal of physiology. Heart and circulatory physiology.

Effects of insulin-like growth factor-I on cultured human coronary artery smooth muscle cells.

A. Bayés‐Genís, R. Schwartz, C. Conover, 2003, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Differential regulation of pregnancy associated plasma protein-A in human coronary artery endothelial cells and smooth muscle cells.

C. Conover, L. Bale, S. Harrington, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

The Association of Early Dietary Supplementation with Vitamin E with the Incidence of Ulcerative Dermatitis in Mice on a C57BL/6 Background: Diet and Ulcerative Dermatitis in Mice.

C. Conover, L. Bale, N. Gades, 2010, Scandinavian journal of laboratory animal science = Scand las nyt : official quarterly journal of the Scandinavian Federation for Laboratory Animal Science.

Brain-specific PAPP-A knock-out mice?

C. Conover, L. Bale, Sally A. West, 2021, Experimental Gerontology.

Cellular characterization of human epicardial adipose tissue: highly expressed PAPP‐A regulates insulin‐like growth factor I signaling in human cardiomyocytes

R. Frye, H. Schaff, C. Conover, 2019, Physiological Reports.

Targeted Inhibition of Pregnancy-Associated Plasma Protein-A Activity Reduces Atherosclerotic Plaque Burden in Mice

C. Conover, C. Oxvig, L. Bale, 2016, Journal of Cardiovascular Translational Research.

Inducible knock out of pregnancy-associated plasma protein-a gene expression in the adult mouse: effect on vascular injury response.

C. Conover, D. Powell, L. Bale, 2013, Endocrinology.

Transforming growth factor-beta1 modulates insulin-like growth factor binding protein-4 expression and proteolysis in cultured periosteal explants.

Joseph H. Schwab, C. Conover, L. Bale, 2010, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Pregnancy‐associated plasma protein‐A (PAPP‐A) expression and insulin‐like growth factor binding protein‐4 protease activity in normal and malignant ovarian surface epithelial cells

C. Conover, M. Overgaard, C. Oxvig, 2004, International journal of cancer.

Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.

L. Giudice, C. Conover, M. Overgaard, 2002, The Journal of clinical endocrinology and metabolism.

Pregnancy-associated plasma protein-A deficiency improves survival of mice on a high fat diet

C. Conover, L. Bale, R. Marler, 2015, Experimental Gerontology.