D. Coy

A. Schally, D. Coy, A. Arimura, 1975, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat

D. Coy, T. Bivalacqua, H. Champion, 2001, Peptides.

Characterization of a putative cellular receptor for HIV-1 transmembrane glycoprotein using synthetic peptides.

D. Coy, R. Garry, L. Henderson, 1990, AIDS.

Solid-phase synthesis of porcine vasoactive intestinal peptide.

D. Coy, J. Gardner, 2009, International journal of peptide and protein research.

EFFECTS OF PROSOMATOSTATIN ON GROWTH HORMONE AND PROLACTIN RESPONSE TO ARGININE IN MAN Comparison with Somatostatin

D. Coy, M. Rodríguez-Arnao, S. Rainbow, 1981, The Lancet.

Reversal of Somatostatin Inhibition of Insulin and Glucagon Secretion

A. Schally, D. Coy, S. Bhathena, 1976, Diabetes.

Inhibition by six somatostatin analogs of plasma growth hormone levels stimulated by thiamylal and morphine in the rat

A. Schally, D. Coy, A. Arimura, 1976, Molecular and Cellular Endocrinology.

Somatostatin receptor subtypes mediate contractility on human colonic smooth muscle cells

R. Jensen, U. Pagotto, G. delle Fave, 2006, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Growth hormone release inhibiting hormone: actions on thyrotrophin and prolactin secretion after thyrotrophinreleasing hormone.

D. Weightman, A. Kastin, A. Schally, 1975, British medical journal.

Observations on the growth hormone, insulin, and glucagon release-inhibiting activities of somatostatin analogues.

A. Schally, D. Coy, A. Arimura, 1978, Metabolism: clinical and experimental.

Effect of Somatostatin Analogs on Gastric and Pancreatic Secretion 1

D. Coy, S. Konturek, A. Dembiński, 1977, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.

A. Schally, D. Coy, S. Konturek, 1976, Gastroenterology.

Identification of the neurotransmitter/neuromodulator functions of the neuropeptide gastrin-releasing peptide in the porcine antrum, using the antagonist (Leu13-psi-CH2 NH-Leu14)-bombesin.

J. Holst, H. Harling, D. Coy, 1990, Scandinavian journal of gastroenterology.

Somatostatin antagonist analog increases GH, insulin, and glucagon release in the rat

D. Coy, W. Murphy, J. Sueiras-diaz, 1982, Peptides.

Radioimmunoassay of somatostatin.

A. Schally, D. Coy, A. Arimura, 1978, Metabolism: clinical and experimental.

Gliclazide directly inhibits arginine-induced glucagon release.

J. Holst, E. Cerasi, D. Coy, 2002, Diabetes.

Role of vagal fibers and bombesin/gastrin-releasing peptide-neurons in distention-induced gastrin release in rats

D. Coy, M. Classen, V. Schusdziarra, 1997, Regulatory Peptides.

Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion

D. Coy, S. Wank, Craig J. Thomas, 2010, Proceedings of the National Academy of Sciences.

Role of endogenous bombesin-peptides during vagal stimulation of gastric acid secretion in the rat

D. Coy, M. Classen, V. Schusdziarra, 1996, Neuropeptides.

Gastrin secretion from human antral G cells in culture.

R. Pederson, D. Coy, A. Buchan, 1990, Gastroenterology.

Galanin: structure-dependent effect on pancreatic amylase secretion and jejunal strip contraction.

D. Coy, M. Mills, Z. Mungan, 1993, European journal of pharmacology.

STRUCTURE-DEPENDENT INHIBITORY EFFECT OF GALANIN ON INSULIN, GASTRIC ACID AND PANCREATIC AMYLASE SECRETION IN RAT

D. Coy, W. Rossowski, 1993 .

Adenohypophyseal response to hypophysiotropic hormones in male obese Zucker rats.

D. Coy, M. Heiman, V. Lance, 1985, The American journal of physiology.

Galanin binding sites in rat gastric and jejunal smooth muscle membrane preparations

D. Coy, W. Rossowski, A. Ertan, 1990, Peptides.

Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude mice.

J. Fuselier, D. Coy, Lichun Sun, 2004, Anticancer research.

Low doses of naloxone and MIF-1 peptides increases fluid consumption in rats

R. Olson, A. Kastin, D. Coy, 1981, Pharmacology Biochemistry and Behavior.

Endogenous opiates: 1979

R. Olson, A. Kastin, D. Coy, 1980, Peptides.

MIF-I suppresses deprivation-induced fluid consumption in rats

R. Olson, A. Kastin, D. Coy, 1980, Peptides.

Antagonistic actions of MIF-I on the hypothermia and hypomotility induced by beta-endorphin or morphine.

A. Kastin, D. Coy, S. Yehuda, 1980, The International journal of neuroscience.

MIF-I's differential actions as an opiate antagonist

R. Olson, A. Kastin, A. Schally, 1979, Pharmacology Biochemistry and Behavior.

Modulation of secretin release by neuropeptides in secretin-producing cells.

C. Chang, D. Coy, W. Chey, 1998, The American journal of physiology.

Structural requirements for the activation of rat anterior pituitary adenylate cyclase by growth hormone-releasing factor (GRF): discovery of (N-Ac-Tyr1, D-Arg2)-GRF(1-29)-NH2 as a GRF antagonist on membranes.

D. Coy, M. Heiman, P. de Neef, 1985, Endocrinology.

Interaction of growth hormone-releasing factor (GRF) and 14 GRF analogs with vasoactive intestinal peptide (VIP) receptors of rat pancreas. Discovery of (N-Ac-Tyr1,D-Phe2)-GRF(1-29)-NH2 as a VIP antagonist.

D. Coy, P. de Neef, P. Robberecht, 1985, Endocrinology.

Bioactivity of growth hormone releasing hormone (1–29) analogues after SC injection in man

T. Aitman, R. Clayton, D. Coy, 1989, Peptides.

Novel urotensin II (UII) antagonists point to multiple receptor involvement in UII bioactivity

J. Taylor, D. Coy, S. Hocart, 2000, Regulatory Peptides.

Suppression of LH-RH-induced ovulation in hamsters and rats by synthetic analogues of LH-RH.

A. Schally, D. Coy, A. Arimura, 1976, Journal of reproduction and fertility.

Comparison of the anti-LH/FSH-RH and anti-ovulatory activities of (D-Phe2, D-Leu6)-LH-RH and (D-Phe2, D-Ala6)-LH-RH.

A. Schally, D. Coy, A. Arimura, 1976, Endocrine research communications.

Glucagon responses to exercise-induced hypoglycaemia are improved by somatostatin receptor type 2 antagonism in a rat model of diabetes

R. Liggins, M. Vranic, M. Riddell, 2016, Diabetologia.

Vasoactive intestinal peptide reduces oxidative stress in pancreatic acinar cells through the inhibition of NADPH oxidase

R. Jensen, D. Coy, R. Takayanagi, 2011, Peptides.

CNS effects of somatostatin.

A. Kastin, A. Schally, D. Coy, 1978, Metabolism: clinical and experimental.

Characterization of Vasoactive Intestinal Peptide (VIP) receptors in mammalian lung

P. Sever, K. Dickinson, D. Coy, 1986, Peptides.

Bombesin-like peptides and mast cell responses: relevance to bronchopulmonary dysplasia?

Y. Miller, K. Wada, K. Sugiyama, 2003, American journal of respiratory and critical care medicine.

A comparison of the effects of human and ovine corticotropin-releasing hormone on the pituitary-adrenal axis.

A. Grossman, D. Coy, J. Newell-Price, 1995, The Journal of clinical endocrinology and metabolism.

[D‐Ala1, Leu9‐ψ‐CH2NH‐Leu0]Neuromedin C Antagonizes Neuromedin C‐Stimulated Amylase Release by Acini Isolated from the Rat Pancreas

D. Coy, B. G. Xue, I. Renner, 1990, Pancreas.

Small cell lung cancer bombesin receptors are antagonized by reduced peptide bond analogues.

G. Fiskum, D. Coy, T. Moody, 1989, Life sciences.

Synthesis and biological actions of prosomatostatin.

A. Schally, D. Coy, W. Murphy, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Somatostatin and its Analogs.

D. Coy, Lichun Sun, 2016, Current drug targets.

Lanreotide and its Potential Applications in Polycystic Kidney and Liver Diseases.

D. Coy, Lichun Sun, Cuiyun Yu, 2015, Current topics in medicinal chemistry.

Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics.

J. Fuselier, D. Coy, Lichun Sun, 2012, The oncologist.

Development of High Affinity Camptothecin-Bombesin Conjugates That Have Targeted Cytotoxicity for Bombesin Receptor-containing Tumor Cells*

R. Jensen, T. Moody, J. Fuselier, 2004, Journal of Biological Chemistry.

Characterization of putative GRP- and NMB-receptor antagonist's interaction with human receptors

R. Jensen, T. Moody, D. Coy, 2009, Peptides.

Comparative pharmacology of the nonpeptide neuromedin B receptor antagonist PD 168368.

R. Jensen, D. Coy, J. Battey, 1999, The Journal of pharmacology and experimental therapeutics.

Interaction of galanin fragments with galanin receptors on isolated smooth muscle cells from guinea pig stomach: identification of a novel galanin receptor subtype.

R. Jensen, D. Coy, T. Pradhan, 1995, The Journal of pharmacology and experimental therapeutics.

Characterization of bombesin receptors using a novel, potent, radiolabeled antagonist that distinguishes bombesin receptor subtypes.

R. Jensen, D. Coy, H. Frucht, 1993, Molecular pharmacology.

Reduced peptide bond pseudopeptide analogues of secretin. A new class of secretin receptor antagonists.

R. Jensen, D. Coy, S. Hocart, 1991, The Journal of biological chemistry.

Combined Endopeptidase Inhibition and Adrenomedullin in Sheep With Experimental Heart Failure

G. Cooper, D. Coy, A. Richards, 2002, Hypertension.

Inhibition of rat prostate tumor growth by an octapeptide analog of somatostatin.

D. Coy, V. Lance, J. Moreau, 1987, Life sciences.

Conformational study of super-active analogues of somatostatin with reduced ring size by XXXH nmr

D. Coy, C. Wynants, G. V. Binst, 1988 .

GIP6–30amide contains the high affinity binding region of GIP and is a potent inhibitor of GIP1–42action in vitro

R. Pederson, C. Mcintosh, M. Wheeler, 1997, Regulatory Peptides.

Pituitary adenylate cyclase-activating polypeptide is a potent broad-spectrum antimicrobial peptide: Structure-activity relationships

W. Wimley, D. Coy, Jing He, 2018, Peptides.

THE INTERACTION OF GROWTH HORMONE RELEASING HORMONE WITH OTHER HYPOTHALAMIC HORMONES ON THE RELEASE OF ANTERIOR PITUITARY HORMONES

A. Grossman, D. Coy, A. Kruseman, 1986, Clinical endocrinology.

Growth hormone responses to growth hormone-releasing hormine (1–29)-NH2 and a D-Ala2 analog in normal men

D. Coy, R. Millar, J. Barron, 1985, Peptides.

Response of human lung tumor xenografts to treatment with a somatostatin analogue (Somatuline).

A. Bogdén, J. Taylor, D. Coy, 1990, Cancer research.

Cardiopulmonary pharmacology of enkephalins in the conscious dog

A. Kastin, D. Coy, T. Giles, 1981, Peptides.

Effect of bombesin antagonist D-Phe6-BN(6-13)OMe on vagally induced gastrin release from perfused rat stomach.

D. Coy, M. Classen, V. Schusdziarra, 1993, Life sciences.

Somatostatin receptor subtype 2 mediates inhibition of gastrin and histamine secretion from human, dog, and rat antrum.

D. Coy, A. Arimura, M. Schubert, 1996, Gastroenterology.

Examination of somatostatin involvement in the inhibitory action of GIP, GLP‐1, amylin and adrenomedullin on gastric acid release using a new SRIF antagonist analogue

D. Coy, W. Rossowski, B. Cheng, 1998, British journal of pharmacology.

Delta sleep-inducing peptide (DSIP)-like material is absorbed by the gastrointestinal tract of the neonatal rat.

W. Banks, A. Kastin, D. Coy, 1983, Life sciences.

SSTR2 mediates the somatostatin-induced increase in intracellular Ca(2+) concentration and insulin secretion in the presence of arginine vasopressin in clonal beta-cell HIT-T15.

D. Coy, S. Yibchok-anun, W. Hsu, 2002, Life sciences.

N-Methyl scan of somatostatin octapeptide agonists produces interesting effects on receptor subtype specificity.

J. Taylor, D. Coy, S. Hocart, 2001, Journal of medicinal chemistry.

Somatostatin Receptor-mediated Signaling in Smooth Muscle

G. Makhlouf, D. Coy, K. Murthy, 1996, The Journal of Biological Chemistry.

CRF IN THE DIFFERENTIAL DIAGNOSIS OF CUSHING'S SYNDROME: A COMPARISON WITH THE DEXAMETHASONE SUPPRESSION TEST

A. Grossman, M. Savage, D. Coy, 1988, Clinical endocrinology.

In Vitro and in Vivo Antitumor Effects of Cytotoxic Camptothecin-Bombesin Conjugates Are Mediated by Specific Interaction with Cellular Bombesin Receptors

R. Jensen, T. Moody, J. Fuselier, 2006, Journal of Pharmacology and Experimental Therapeutics.

Pharmacology and intracellular signaling mechanisms of the native human orphan receptor BRS-3 in lung cancer cells.

R. Jensen, D. Coy, S. Mantey, 1998, The Journal of pharmacology and experimental therapeutics.

Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors.

R. Jensen, D. Coy, S. Mantey, 1995, European journal of pharmacology.

GRP-receptor-mediated signal transduction, gene expression and DNA synthesis in the human pancreatic adenocarcinoma cell line HPAF

T. Gress, D. Coy, B. Burghardt, 2001, Peptides.

Antagonistic activity of analogs of luteinizing hormone-releasing hormone (LH-RH) in vitro

A. Schally, D. Coy, F. Labrie, 1976, Molecular and Cellular Endocrinology.

INHIBITORY ACTIVITY OF ANALOGUES OF LUTEINIZING HORMONE‐RELEASING HORMONE (LH‐RH) IN VITRO AND IN VIVO

A. Schally, D. Coy, F. Labrie, 1976, Clinical endocrinology.

Inhibitory activity of four analogs of luteinizing hormone-releasing hormone in vivo.

A. Schally, D. Coy, F. Labrie, 1975, Fertility and sterility.

Inhibition of growth hormone and thyrotropin release by growth hormone-release inhibiting hormone.

J. Drouin, A. Schally, D. Coy, 1974, Molecular and cellular endocrinology.

Parallel stimulation of cyclic AMP accumulation and LH and FSH release by analogs of LH-RH in vitro

A. Schally, D. Coy, N. Yanaihara, 1974 .

Hypothalamic Hormones Regulating Pituitary (and Other) Functions: Their Physiology and Biochemistry as Well as Recent Studies with Their Synthetic Analogues

K. Chihara, A. Kastin, A. Schally, 1979 .

ANALOGUES OF GROWTH-HORMONE RELEASE-INHIBITING HORMONE

C. H. Mortimer, A. Kastin, A. Schally, 1975, The Lancet.

In Vitro Histamine Release with LHRH Analogs

D. Coy, K. Folkers, W. Hook, 1987 .

HYPOTHALAMIC HORMONE INTERACTION IN ACROMEGALY

A. Kastin, A. Schally, D. Coy, 1975, Clinical endocrinology.

Stimulation of cyclic AMP accumulation and corticotropin release by synthetic ovine corticotropin-releasing factor in rat anterior pituitary cells: site of glucocorticoid action.

V. Giguère, A. Schally, D. Coy, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacology of GRF and Somatostatin: Positive and Negative Control of GH Release

D. Coy, S. Hocart, John E. Taylor, 1994 .

Desmethionine alkylamide bombesin analogues: a new class of bombesin receptor antagonists with potent antisecretory activity in pancreatic acini and antimitotic activity in Swiss 3T3 cells.

R. Jensen, L. Wang, J. Taylor, 1990, Biochemistry.

Potent, highly selective inhibition of growth hormone secretion by position 4 somatostatin analogs.

D. Coy, W. Murphy, C. Meyers, 1981, Endocrinology.

Development of a potent bombesin receptor antagonist with prolonged in vivo inhibitory activity on bombesin-stimulated amylase and protein release in the rat

R. Jensen, D. Coy, Z. Mungan, 1992, Peptides.

Reduced gastric acid inhibitory effect of a pGIP(1–30)NH2 fragment with potent pancreatic amylase inhibitory activity

D. Coy, Z. Mungan, W. Rossowski, 1992, Regulatory Peptides.

Comparison of prolonged in vivo inhibitory activity of several potent bombesin (BN) antagonists on BN-stimulated amylase secretion in the rat

D. Coy, W. Rossowski, A. Ertan, 1991, Peptides.

Comparative Pharmacology of Bombesin Receptor Subtype-3, Nonpeptide Agonist MK-5046, a Universal Peptide Agonist, and Peptide Antagonist Bantag-1 for Human Bombesin Receptors

R. Jensen, M. Reitman, D. Coy, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Molecular Basis for Agonist Selectivity and Activation of the Orphan Bombesin Receptor Subtype 3 Receptor

R. Jensen, S. Portal-Nuñez, D. Coy, 2008, Journal of Pharmacology and Experimental Therapeutics.

Identification of Bombesin Receptor Subtype-Specific Ligands: Effect of N-Methyl Scanning, Truncation, Substitution, and Evaluation of Putative Reported Selective Ligands

R. Jensen, D. Coy, M. Schumann, 2006, Journal of Pharmacology and Experimental Therapeutics.

Ability of Various Bombesin Receptor Agonists and Antagonists to Alter Intracellular Signaling of the Human Orphan Receptor BRS-3*

J. Battey, R. Jensen, D. Coy, 1998, The Journal of Biological Chemistry.

Edward T. Tyler Prize Oration: LH-releasing hormone and its analogues: recent basic and clinical investigations.

A. Kastin, A. Schally, D. Coy, 1976, International journal of fertility.

Activation of Somatostatin Receptor Subtype 2 Inhibits Insulin Secretion in the Isolated Perfused Human Pancreas

T. Adrian, W. Fisher, D. Coy, 2003, Pancreas.

Activation of human somatostatin receptor type 2 causes inhibition of cell growth in transfected HEK293 but not in transfected CHO cells.

G. Bell, F. Brunicardi, D. Coy, 1997, The Journal of surgical research.

High affinity binding of [125I-Tyr11]somatostatin-14 to human small cell lung carcinoma (NCI-H69).

J. Taylor, D. Coy, J. Moreau, 1988, Life sciences.

CHAPTER 26 – Multiple Independent Actions of Neuropeptides on Behavior

R. Olson, C. Sandman, A. Kastin, 1981 .

Differential effects of N-terminal modifications on the biological potencies of growth hormone releasing factor analogues with varying chain lengths.

D. Coy, M. Heiman, V. Lance, 1987, Journal of medicinal chemistry.

Structure-activity studies on the N-terminal region of growth hormone releasing factor.

D. Coy, V. Lance, W. Murphy, 1985, Journal of medicinal chemistry.

Effect of Ala-2-D-Trp-8-D-Cys-14-somatostatin on the arginine induced release of insulin, GH and glucagon in normal men.

A. Schally, D. Coy, W. Murphy, 1984, Endocrine research.

Pharmacology and selectivity of various natural and synthetic bombesin related peptide agonists for human and rat bombesin receptors differs

R. Jensen, D. Coy, V. Sancho, 2011, Peptides.

Pharmacology of putative selective hBRS-3 receptor agonists for human bombesin receptors (BnR): Affinities, potencies and selectivity in multiple native and BnR transfected cells

R. Jensen, T. Moody, D. Coy, 2010, Peptides.

Effects of camptothecin on tumor cell proliferation and angiogenesis when coupled to a bombesin analog used as a targeted delivery vector

J. Fuselier, D. Coy, Lichun Sun, 2007, Anti-cancer drugs.

Studies on the interaction of endorphins, substance P. and endogenous somatostatin in growth hormone and prolactin release in rats.

K. Chihara, A. Schally, D. Coy, 1978, Endocrinology.

Comparison of the inhibition of histamine-and pentagastrin-stimulated gastric acid secretion by somatostatin in the cat

A. Schally, D. Coy, A. Gómez-Pan, 1977, Agents and Actions.

Characteristics of [D-Trp8]-somatostatin-sensitive B50 phosphorylation

D. Coy, L. Dokas, M. Klis, 1985, Peptides.

Somatostatin and analogs inhibit endogenous synaptic plasma membrane protein phosphorylation in vitro.

D. Coy, W. Gispen, L. Dokas, 1983, European journal of pharmacology.

Comparison of enkephalin and atropine in the inhibition of vagally stimulated gastric and pancreatic secretion and gastrin and pancreatic polypeptide release in dogs

D. Coy, S. Konturek, W. Bielański, 1982, Peptides.

Autocrine/paracrine regulation of breast cancer cell proliferation by growth hormone releasing hormone via Ras, Raf, and mitogen-activated protein kinase.

A. Bradford, D. Coy, G. Siriwardana, 2006, Molecular endocrinology.

Receptor binding and adenylate cyclase activities of glucagon analogues modified in the N-terminal region.

V. Hruby, D. Johnson, D. Coy, 1986, Biochemistry.

μ-Opiate binding and morphine antagonism by octapeptide analogs of somatostatin

W. Bowen, J. Walker, D. Coy, 1987, Peptides.

Receptor-selective somatostatin (SRIF) analogs

D. Coy, M. Heiman, John E. Taylor, 1988 .

Solid phase reductive alkylation techniques in analogue peptide bond and sidechain modification

D. Coy, S. Hocart, Y. Sasaki, 1988 .

Structure-activity studies on the N-terminal region of glucagon.

D. Coy, V. Lance, W. Murphy, 1984, Journal of medicinal chemistry.

Analogs of luteinizing hormone-releasing hormone with increased biological activity produced by D-amino acid substitutions in position 6.

A. Schally, D. Coy, E. Coy, 1976, Journal of medicinal chemistry.

Highly active position eight analogues of somatostatin and separation of peptide diastereomers by partition chromatography.

A. Schally, D. Coy, C. Meyers, 1978, Biochemistry.

Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.

G. Liapakis, G. Melacini, L. Prokai, 1997, Journal of medicinal chemistry.

Dissociation of the effects of amylin on osteoblast proliferation and bone resorption.

I. Reid, J. Cornish, K. Callon, 1998, The American journal of physiology.

Dissociation of the effects of amylin on osteoblast proliferation and bone resorption.

I. Reid, J. Cornish, K. Callon, 1998, American journal of physiology. Endocrinology and metabolism.

GIP(6-30amide) contains the high affinity binding region of GIP and is a potent inhibitor of GIP1-42 action in vitro.

R. Pederson, C. Mcintosh, M. Wheeler, 1997, Regulatory peptides.

Effect of substitutions in position 12 of bombesin on antagonist activity

R. Jensen, D. Coy, J. Gardner, 1989, Peptides.

Probing peptide backbone function in bombesin. A reduced peptide bond analogue with potent and specific receptor antagonist activity.

R. Jensen, J. Taylor, D. Coy, 1988, The Journal of biological chemistry.

Corticotropin-releasing factor stimulates secretion of melanocyte-stimulating hormone from the rat pituitary.

D. Coy, F. Labrie, J. Cǒté, 1982, Science.

Potent antagonists of somatostatin: synthesis and biology.

J. Taylor, D. Coy, S. Hocart, 1998, Journal of medicinal chemistry.

Receptor-specific somatostatin analogs: correlations with biological activity.

J. Taylor, D. Coy, David H. Coy, 1996, Metabolism: clinical and experimental.

Somatostatin analogues and multiple receptors: possible physiological roles.

D. Coy, W. Rossowski, 1995, Ciba Foundation symposium.

Characterization of somatostatin receptor subtypes controlling rat gastric acid and pancreatic amylase release

R. Jensen, U. Akarca, D. Coy, 1994, Peptides.

The New Pharmacology of Somatostatin and its Multiple Receptors

D. Coy, T. Reisine, W. Murphy, 1993, The Journal of pediatric endocrinology.

Anovulatory effect of a LHRH antagonist in women.

A. Zarate, A. Schally, D. Coy, 1981, Contraception.

Inhibition of the postcastration rise of luteinizing hormone and follicle-stimulating hormone in female rhesus monkeys (Macaca mulatta) by the administration of a luteinizing hormone-releasing hormone inhibitory analog ([N-Ac-D-Trp1-3,D-p-Cl-phe2,D-Phe6,D-Ala10]-LH-RH).

A. Schally, D. Coy, J. Balmaceda, 1981, Fertility and sterility.

LH‐RH Agonists and Antagonists

A. Schally, D. Coy, A. Arimura, 1980, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Covalently cyclized agonist and antagonist analogues of bombesin and related peptides.

R. Jensen, D. Coy, H. Frucht, 1991, The Journal of biological chemistry.

Reduced peptide bond pseudopeptide analogues of substance P. A new class of substance P receptor antagonists with enhanced specificity.

R. Jensen, D. Coy, J. Gardner, 1989, The Journal of biological chemistry.

Solid phase synthesis of peptides containing the CH2NH peptide bond isostere

D. Coy, Y. Sasaki, 1987, Peptides.

Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on passive and active avoidance behavior and on open-field activity of rats

L. Vécsei, A. Schally, D. Coy, 1982, Pharmacology Biochemistry and Behavior.

Isolation and structure of several peptides from porcine hypothalami.

A. Schally, D. Coy, A. Arimura, 1980, Biochimica et biophysica acta.

Isolation, structural elucidation and synthesis of a tetradecapeptide with in vitro ACTH-releasing activity corresponding to residues 33-46 of the alpha-chain of porcine hemoglobin.

K. Chihara, A. Schally, D. Coy, 1978, Biochemical and biophysical research communications.

Inhibitory effect of somatostatin-28 on pancreatic polypeptide, glucagon and insulin secretion in normal man.

I. Correas, A. Schally, D. Coy, 1983, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Human pancreatic polypeptide inhibits insulin release in the rat.

D. Coy, W. Murphy, C. Meyers, 1981, Biochemical and biophysical research communications.

Neuromedin B receptors retain functional expression when transfected into BALB 3T3 fibroblasts: analysis of binding, kinetics, stoichiometry, modulation by guanine nucleotide-binding proteins, and signal transduction and comparison with natively expressed receptors.

R. Jensen, R. Benya, L. Wang, 1992, Molecular pharmacology.

Systematic development of bombesin/gastrin-releasing peptide antagonists.

R. Jensen, A. Bogdén, D. Coy, 1992, Journal of the National Cancer Institute. Monographs.

Regulation of gastric function by endogenous gastrin releasing peptide in humans: studies with a specific gastrin releasing peptide receptor antagonist

C. Beglinger, D. Coy, P. Hildebrand, 2001, Gut.

NEW HYPOTHALAMIC HORMONE, CORTICOTROPIN-RELEASING FACTOR, SPECIFICALLY STIMULATES THE RELEASE OF ADRENOCORTICOTROPIC HORMONE AND CORTISOL IN MAN

A. Grossman, A. Schally, D. Coy, 1982, The Lancet.

Prolonged Release of LH and FSH and Depletion of Pituitary Gonadotropin Content after Administration of [d-LEU6, desGly-NH2 10]-LH-RH Ethylamide 1

A. Schally, D. Coy, A. Arimura, 1977, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Unusual Anti-Reproductive Properties of the Analog [d-Leu6,Des-Gly- N H 2 10 ]-Luteinizing Hormone-Releasing Hormone Ethylamide in Male Rats**Supported in part by National Institutes of Health Grant 5 P50 HD08338.

A. Schally, D. Coy, A. Steinberger, 1978 .

Organ distribution of radioactivity and disappearance of radioactivity from plasma after administration of (3H) luteinizing hormone-releasing hormone to mice and rats.

A. Schally, D. Coy, F. Labrie, 1974, Neuroendocrinology.

THE EFFECT OF OVINE CORTICOTROPHIN‐RELEASING FACTOR ON THE HORMONAL RESPONSE TO INSULIN‐INDUCED HYPOGLYCAEMIA

A. Grossman, D. Coy, A. White, 1989, Clinical endocrinology.

Corticotropin-releasing factor stimulates accumulation of adenosine 3', 5'-monophosphate in rat pituitary corticotrophs.

A. Schally, D. Coy, F. Labrie, 1982, Science.

Bombesin receptor antagonists: different classes and cellular basis of action.

R. Jensen, D. Coy, J. Mrozinski, 1993, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Somatostatin‐receptor 2 (sst2)‐mediated effects of endogenous somatostatin on exocrine and endocrine secretion of the rat stomach

D. Coy, A. Sandvik, H. Waldum, 2005, British journal of pharmacology.

Evidence that [125I]N-Tyr-delta sleep-inducing peptide crosses the blood-brain barrier by a non-competitive mechanism

W. Banks, A. Kastin, D. Coy, 1984, Brain Research.

Somatostatin receptor-targeted anti-cancer therapy.

D. Coy, Lichun Sun, 2011, Current drug delivery.

Exploration of the DTrp-NMeLys motif in the search for potent somatostatin antagonists.

D. Coy, John E. Taylor, W. Murphy, 2002, Bioorganic & medicinal chemistry.

Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats.

Y. Taché, D. Coy, J. Rivier, 2000, The Journal of pharmacology and experimental therapeutics.

Specific inhibition of rat pancreatic insulin or glucagon release by receptor-selective somatostatin analogs.

D. Coy, W. Rossowski, D. Coy, 1994, Biochemical and biophysical research communications.

des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor antagonists, partial agonists, or agonists.

R. Jensen, L. Wang, J. Taylor, 1990, The Journal of biological chemistry.

A selective somatostatin type-2 receptor agonist inhibits neointimal thickening and enhances endothelial cell growth and morphology following aortic balloon injury in the rabbit

D. Coy, V. Fonseca, P. Kadowitz, 2002, Molecular and Cellular Biochemistry.

Peptide-Neuromedin B (NMB) Receptor Interactions: Comparison with Gastrin-Releasing Peptide (GRP) Receptor Interactions

R. Jensen, R. Benya, D. Coy, 1993 .

The use of pigs as an animal model to evaluate the efficacy, potency and specificity of two growth hormone releasing factor analogues.

D. Coy, T. Abribat, C. Farmer, 2001, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats

T. Adrian, D. Coy, R. Reidelberger, 1994, Peptides.

Pharmacology and cell biology of the bombesin receptor subtype 4 (BB4-R).

R. Jensen, M. Akeson, D. Coy, 1999, Biochemistry.

The novel VIP-like hypothalamic polypeptide PACAP interacts with high affinity receptors in the human neuroblastoma cell line NB-OK

L. Buscail, D. Coy, A. Arimura, 1990, Peptides.

Effects of analogs of (pyro)Glu-His-Gly-OH on food consumption and gastric acid secretion in rats.

A. Schally, D. Coy, J. Jaworek, 1984, Life sciences.

Inhibition of Sham Feeding-Induced Gastric Secretion and Serum Hormonal Responses by Analogs of (pyro)Glu-His-Gly-OH

A. Schally, D. Coy, R. Medina‐Santillán, 1982, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Dynamics of injected somatostatin in blood of patients with hepatic failure and acromegaly

A. Kastin, A. Schally, D. Coy, 1980, Peptides.

Selectivity for binding of peptide analogs to vascular receptors for vasoactive intestinal peptide.

D. Coy, A. Fournier, O. Rorstad, 1990, Molecular pharmacology.

Solid-phase synthesis of human pancreatic polypeptide.

D. Coy, C. Meyers, 2009, International journal of peptide and protein research.

Synthesis and characterization of multiply-tyrosinated, multiply-iodinated somatostatin analogs.

J. Fuselier, D. Coy, E. Woltering, 1999, The journal of peptide research : official journal of the American Peptide Society.

The effect of drug dose and drug exposure time on the binding, internalization, and cytotoxicity of radiolabeled somatostatin analogs.

C. Hornick, J. Fuselier, D. Coy, 2004, The Journal of surgical research.

A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon

D. Coy, T. O'Dorisio, F. Christofi, 2003, Regulatory Peptides.

Novel heptapeptide somatostatin analog displays anti-tumor activity independent of effects on growth hormone secretion.

J. Taylor, D. Coy, J. Moreau, 1989, Peptide research.

Inhibition of growth of a prolactin-secreting pituitary tumor in rats by analogs of luteinizing hormone-releasing hormone and somatostatin.

I. Torres-Aleman, A. Schally, D. Coy, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Effect of growth hormone-release inhibiting hormone on hormones stimulating exocrine pancreatic secretion.

D. Coy, S. Konturek, J. Tasler, 1976, The Journal of clinical investigation.

Effects of somatostatin and a somatostatin agonist on diet-induced pancreatitis in mice

D. Coy, A. Arimura, A. Ertan, 1985, Peptides.

Brain β-endorphin-like immunoreactivity in adult rats given β-endorphin neonatally

C. Sandman, A. Kastin, D. Coy, 1981, Brain Research Bulletin.

Selective conversion of O-succinimidyl carbamates to N-(O-carbamoyl)-succinmonoamides and ureas

D. Coy, K. Maskos, N. Vasilevich, 2002 .

Adrenomedullin attenuates pressor response to angiotensin II in conscious sheep.

G. Cooper, D. Coy, A. Richards, 2000, Journal of cardiovascular pharmacology.

Intracerebroventricular injection of somatostatin sst5 receptor agonist inhibits gastric acid secretion in rats.

Y. Taché, D. Coy, K. Lloyd, 1996, European journal of pharmacology.

Influence of intracisternal injection of somatostatin analog receptor subtypes 2, 3 and 5 on gastric acid secretion in conscious rats

Y. Taché, D. Coy, V. Martínez, 1995, Neuroscience Letters.

Potent inhibitory activity of [D-Leu6, Des-Gly-NH2(10)]LHRH ethylamide on LH/hCG and PRL testicular receptor levels in the rat.

P. Kelly, A. Schally, D. Coy, 1977, Endocrinology.

Cyclic analogues of luteinizing hormone-releasing hormone with significant biological activities.

A. Schally, D. Coy, J. Seprődi, 1978, Journal of medicinal chemistry.

Uptake of iodinated luteinizing hormone releasing hormone analogs in the pituitary.

A. Schally, D. Coy, J. Reeves, 1977, Endocrinology.

Blockade of ovulation in rats by inhibitory analogs of luteinizing hormone-releasing hormone

A. Schally, D. Coy, A. Arimura, 1976 .

Inhibition of luteinizing hormone release by analogs of luteinizing hormone-releasing hormone (LHRH) in vitro.

A. Schally, D. Coy, F. Labrie, 1976, Endocrinology.

Stereoisomers of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, E. Coy, 1974, Biochemical and biophysical research communications.

Conformational study of somatostatin analogues in methanol at low temperature

D. Coy, P. Verheyden, G. Van Binst, 1991 .

A conjugate of camptothecin and a somatostatin analog against prostate cancer cell invasion via a possible signaling pathway involving PI3K/Akt, alphaVbeta3/alphaVbeta5 and MMP-2/-9.

J. Fuselier, D. Coy, Lichun Sun, 2007, Cancer letters.

Mu and delta opiate receptors in rat brain are affected by GTP but not by MIF-1

A. Kastin, D. Coy, J. Zadina, 1981, Brain Research Bulletin.

Effect of intracerebroventricular administration of β-/Tyr9/-melanotropin-/9–18/ on rotational behavior induced by substantia nigra lesion in rats

L. Vécsei, A. Schally, D. Coy, 1983, Neuropeptides.

Effects of β-/Tyr9/melanotropin-/9–18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine

L. Vécsei, A. Schally, D. Coy, 1982, Neuropeptides.

CRF-41 stimulates the release of β-lipotrophin and β-endorphin in normal human subjects

A. Grossman, A. Schally, D. Coy, 1984 .

Endogenous opiates: 1981

R. Olson, A. Kastin, D. Coy, 1982, Peptides.

Short chain bombesin pseudopeptides with potent bombesin receptor antagonist activity in rat and guinea pig pancreatic acinar cells.

L. Wang, D. Coy, R. Jensen, 1990, European journal of pharmacology.

Short-chain pseudopeptide bombesin receptor antagonists with enhanced binding affinities for pancreatic acinar and Swiss 3T3 cells display strong antimitotic activity.

R. Jensen, L. Wang, J. Taylor, 1989, The Journal of biological chemistry.

Naloxone-reversible effects of d-Ala2-Met5-enkephalinamide-induced behavioral activity in rats.

W. Dunlap, C. Harston, D. Coy, 1980, Behavioral and neural biology.

Leucine-enkephalin: reversal of intrinsic cardiovascular stimulation by pentobarbital.

A. Kastin, D. Coy, T. Giles, 1982, European journal of pharmacology.

Some analogs of Tyr-MIF-1 affect passive avoidance behavior but not motor activity in rats

A. Kastin, D. Coy, A. Fischman, 1984, Pharmacology Biochemistry and Behavior.

Tyr-MIF-1 affects passive avoidance behavior but not motor activity in rats

R. Olson, A. Kastin, D. Coy, 1983, Brain Research Bulletin.

The interaction between β-[Tyr9]melanotropin-(9–18), haloperidol and amphetamine in different behavior tests of rats

L. Vécsei, A. Schally, D. Coy, 1982, Pharmacology Biochemistry and Behavior.

Differential effects of neuropeptides on short-term memory in primates

R. Olson, M. Mauk, G. Lahoste, 1981, Peptides.

CNS effects of peripherally administered brain peptides.

R. Olson, A. Kastin, A. Schally, 1979, Life sciences.

Neonatal administration of met-enkephalin facilitates maze performance of adult rats

A. Kastin, A. Schally, D. Coy, 1980, Pharmacology Biochemistry and Behavior.

M. Mauk, A. Kastin, A. Schally, 1980, Physiology & Behavior.

Peripheral administration of hypothalamic peptides results in CNS changes.

L. H. Miller, A. Kastin, A. Schally, 1978, Pharmacological research communications.

Distribution of 3H-α-MSH in rat brain

A. Kastin, A. Schally, D. Coy, 1976, Brain Research Bulletin.

Developmental, behavioral, and opiate receptor changes after prenatal or postnatal β-endorphin, CRF, or Tyr-MIF-1

A. Kastin, D. Coy, J. Zadina, 1985, Psychoneuroendocrinology.

Luteinizing hormone-releasing hormone analogs with increased anti-ovulatory activity.

A. Schally, D. Coy, J. Érchegyi, 1981, Biochemical and biophysical research communications.

Peptides readily penetrate the blood-brain barrier: Uptake of peptides by synaptosomes is passive

A. Kastin, D. Coy, R. Walter, 1976, Pharmacology Biochemistry and Behavior.

Circular dichroism and absorption study of the structure of methionine-enkephalin in solution.

W. Mattice, D. Coy, Richard W. Schwartz, 1978, Biochemical and biophysical research communications.

LH-RH antagonists: Further analogs with ring-substituted aromatic residues

A. Schally, D. Coy, M. Nekola, 1981, Peptides.

Tyrosine-modified analogs of methionine-enkephalin and their effects on the mouse vas deferens

A. Kastin, D. Coy, 1980, Peptides.

Effect of synthetic human pancreatic growth hormone-releasing factors on plasma growth hormone concentrations in lactating cows.

D. Bauman, D. Coy, V. Lance, 1984, Journal of dairy science.

Dissociation of effects of LH-RH analogs on pituitary regulation and reproductive behavior

A. Kastin, A. Schally, D. Coy, 1980, Pharmacology Biochemistry and Behavior.

Synthesis and biological properties of (D-Ala-6, des-Gly-NH2-10)-LH-RH ethylamide, a peptide with greatly enhanced LH- and FSH- releasing activity.

A. Schally, D. Coy, A. Arimura, 1974, Biochemical and biophysical research communications.

Stimulatory and inhibitory analogs of luteinizing hormone releasing hormone.

A. Schally, D. Coy, A. Arimura, 1974, Biochemistry.

Localization and gene expression of the receptor for pituitary adenylate cyclase-activating polypeptide in the rat brain

S. Shioda, D. Coy, A. Arimura, 1997, Neuroscience Research.

Neuropeptides and the blood-brain barrier in goldfish

R. Olson, A. Kastin, D. Coy, 1978, Pharmacology Biochemistry and Behavior.

Stimulation of prolactin release in the rat by intraventricular injection of beta-endorphin and methionine-enkephalin.

D. Coy, F. Labrie, A. Dupont, 1977, Biochemical and biophysical research communications.

Poly(bistrifluoromethylamino)-compounds. Synthesis of NN-bistrifluoromethylamino-substituted allenes and their reaction with trifluoronitrosomethane

D. Coy, M. Newlands, A. E. Tipping, 1970 .

An analog of enkephalin having prolonged opiate-like effects in vivo.

G. Berntson, C. Sandman, J. Walker, 1977, Science.

Gonadotrophin releasing hormone analogues.

A. Schally, D. Coy, 1978, Annals of clinical research.

Effect of a powerful antagonist of LH-RH on testicular function in prepubertal male rats.

A. Schally, D. Coy, L. Debeljuk, 1983, Archives of andrology.

Inhibition of testicular luteinizing hormone receptor level by treatment with a potent luteinizing hormone-releasing hormone agonist of human chorionic gonadotropin.

P. Kelly, A. Schally, D. Coy, 1977, Biochemical and biophysical research communications.

Unusual anti-reproductive properties of the analog [d-Leu6,des-Gly-NH2(10)]-luteinizing hormone-releasing hormone ethylamide in male rats.

A. Schally, D. Coy, A. Steinberger, 1978, Fertility and sterility.

Activated Notch signaling augments cell growth in hepatocellular carcinoma via up-regulating the nuclear receptor NR4A2

Wenbo Yu, D. Coy, Lichun Sun, 2017, Oncotarget.

Neonatal administration of beta-endorphin produces "chronic" insensitivity to thermal stimuli.

C. Berka, C. Sandman, J. Walker, 1979, Life sciences.

Disappearance and excretion of labeled α-MSH in man

A. Kastin, A. Schally, D. Coy, 1978, Pharmacology Biochemistry and Behavior.

Radioimmunoassay of MIF-1/Tyr-MIF-1-like material in rat pineal

A. Kastin, D. Coy, Sharon P. Lawrence, 1980, Pharmacology Biochemistry and Behavior.

Psychopharmacological and endocrinological effects of melanocyte stimulating hormones in normal man

A. Kastin, D. Coy, T. Davies, 1977, Psychopharmacology.

Suppression of postovulatory gonadotropin levels does not affect corpus luteum function in rhesus monkeys.

A. Schally, D. Coy, J. Balmaceda, 1983, The Journal of clinical endocrinology and metabolism.

Gonadotropin-releasing activity of two highly active and long-acting analogs of luteinizing hormone-releasing hormone after subcutaneous, intravaginal, and oral administration.

A. Schally, D. Coy, A. Arimura, 1975, Fertility and sterility.

VIP Attenuation of the Severity of Experimental Pancreatitis Is Due to VPAC1 Receptor-Mediated Inhibition of Cytokine Production

R. Jensen, D. Coy, H. Nawata, 2005, Pancreas.

A chimeric VIP-PACAP analogue but not VIP pseudopeptides function as VIP receptor antagonists

R. Jensen, D. Coy, S. Hocart, 1994, Peptides.

Recent approaches to fertility control based on derivative of LH-RH.

A. Schally, D. Coy, A. Arimura, 1980, Vitamins and hormones.

Interaction of Bombesin and Related Peptides with Receptors on Pancreatic Acinar Cells

R. Jensen, D. Coy, J. Gardner, 1988, Annals of the New York Academy of Sciences.

Tyr-MIF-1 and MIF-1 are active in the water wheel test for antidepressant drugs

A. Kastin, D. Coy, R. Ehrensing, 1984, Pharmacology Biochemistry and Behavior.

Enkephalin and other peptides reduce passiveness

A. Kastin, A. Schally, D. Coy, 1978, Pharmacology Biochemistry and Behavior.

Radioautographic localization of radioactivity in rat brain after intraventricular or intracarotid injection of 3H-L-prolyl-L-leucyl glycinamide

A. Kastin, A. Schally, D. Coy, 1975, Pharmacology Biochemistry and Behavior.

Reduction of distress vocalization in chicks by opiate-like peptides

J. Panksepp, A. Kastin, D. Coy, 1978, Brain Research Bulletin.

Differential penetration of DSIP peptides into rat brain

W. Banks, A. Kastin, D. Coy, 1982, Pharmacology Biochemistry and Behavior.

Endogenous opiates: Through 1978

R. Olson, A. Kastin, D. Coy, 1979, Neuroscience & Biobehavioral Reviews.

The Opioid Neuropeptides Enkephalin and Endorphin and their Hypothesized Relation to Pain

R. Olson, A. Kastin, D. Coy, 1980 .

Systemic administration of endorphins selectively alters open field behavior of rats

C. Sandman, J. Walker, A. Kastin, 1978, Physiology & Behavior.

Effect of [D-Phe6] bombesin (6-13) methylester, a bombesin receptor antagonist, towards bombesin-induced contractions in the guinea-pig and rat isolated urinary bladder.

C. Maggi, D. Coy, S. Giuliani, 1992, Journal of autonomic pharmacology.

New reduced peptide bond substance P agonists and antagonists: effects on smooth muscle contraction.

D. Coy, W. Rossowski, A. Ertan, 1991, European journal of pharmacology.

Evidence for conversion of N-Tyr-MIF-1 into MIF-1 by a specific brain aminopeptidase

A. Kastin, D. Coy, N. Marks, 1984, Neurochemistry International.

Characterization of binding sites for N-Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) in rat brain

E. Krieg, A. Kastin, D. Coy, 1982, Pharmacology Biochemistry and Behavior.

Analgesia after peripheral administration of enkephalin and endorphin analogues

A. Kastin, D. Coy, Michael T. Jemison, 1979, Pharmacology Biochemistry and Behavior.

Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes.

K. Mizuno, D. Coy, A. Arimura, 1991, Endocrinology.

Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells.

M. Culler, N. Minamino, D. Coy, 1989, Biochemical and biophysical research communications.

Radioimmunoassayable N-Tyr-MIF-1-like activity in rat brain is increased by pinealectomy

A. Kastin, D. Coy, Sharon P. Lawrence, 1981, Brain Research Bulletin.

The effects of an LH-RH antagonist ([N-Ac-D-Trp(1)(3), D-p-Cl-Phe(2), D-Phe(6), D-Ala(10)]-LH-RH) during the preovulatory period of the rhesus monkey.

A. Schally, D. Coy, J. Balmaceda, 1981, Contraception.

Effect of reductive alkylation of D-lysine in position 6 on the histamine-releasing activity of luteinizing hormone-releasing hormone antagonists.

D. Coy, S. Hocart, M. Nekola, 1987, Journal of medicinal chemistry.

Improved antagonists of luteinizing hormone-releasing hormone modified in position 7.

D. Coy, S. Hocart, M. Nekola, 1985, Journal of medicinal chemistry.

Effect of the CH2NH and CH2NAc peptide bond isosteres on the antagonistic and histamine releasing activities of a luteinizing hormone-releasing hormone analogue.

D. Coy, S. Hocart, M. Nekola, 1988, Journal of medicinal chemistry.

Antagonistic analogs of luteinizing hormone-releasing hormone are mast cell secretagogues.

D. Coy, S. Hocart, C. O'neil, 1986, International archives of allergy and applied immunology.

Synthesis and biological activity of LH-RH antagonists modified in position 1

A. Schally, D. Coy, M. Nekola, 1982, Peptides.

Novel Tandem Aldol Intramolecular Cyclization of Substituted N-Benzylpiperidine-4-one: Synthesis of Novel-Type Nitrogen 2,8-Phenanthroline Heterocycles

J. Fuselier, D. Coy, Lichun Sun, 2015 .

Alternative bridging groups for proline in endothelin pentapeptide receptor antagonists

J. Taylor, D. Coy, S. Hocart, 1994 .

Clinical comparison of natural LH-RH, synthetic LH-RH, and two analogues of LH-RH.

A. Kastin, A. Schally, D. Coy, 1974, The Journal of clinical endocrinology and metabolism.

Effects of an LHRH antagonist on gonadotrophin and oestradiol secretion, follicular development, oestrus and ovulation in Holstein heifers.

D. Coy, S. Roberge, N. Rawlings, 1989, Journal of reproduction and fertility.

Suppressive effect of an inhibitory LHRH analog on the gonadotropin response to LHRH in normal women.

A. Kastin, A. Zarate, A. Schally, 1980, International journal of fertility.

Response of luteinizing hormone and follicle-stimulating hormone to different doses of D-leucine-6-LH-RH ethylamide in oligospermic patients.

A. Schally, D. Coy, L. Schwarzstein, 1976, Fertility and sterility.

Prolonged anti-luteinizing hormone/follicle-stimulating hormone-releasing activities of some synthetic antagonists of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, A. Arimura, 1976, Fertility and sterility.

Long-acting luteinizing homone-releasing hormone (LH-RH) analogs in the treatment of female infertility.

A. Kastin, A. Zarate, A. Schally, 1976, Archivos de investigacion medica.

Increased and prolonged LH-RH/FSH-RH activity of synthetic (D-Ala6, Des-Gly-NH210)-LH-RH-ethylamide in normal women.

A. Kastin, A. Zarate, A. Schally, 1975, American journal of obstetrics and gynecology.

Luteinizing hormone (LH), follicle-stimulating hormone, and testosterone responses to consecutive injections of D-leucine-6-LH-releasing hormone ethylamide in normal men.

A. Schally, D. Coy, L. Schwarzstein, 1977, Fertility and sterility.

Administration of human pancreatic growth hormone-releasing factor (GRF) analogs enhances responsiveness of cultured rat pituitary cells to GRF.

D. Coy, M. Heiman, V. Lance, 1984, Biochemical and biophysical research communications.

Modulation by galanin of growth hormone and gonadotropin secretion from perifused pituitary and median eminence of prepubertal male calves.

D. Coy, A. Giustina, A. Negro-Vilar, 1997, Neuroendocrinology.

Stimulation of growth hormone release in anesthetized and conscious pigs by synthetic human pancreatic growth hormone-releasing factor [hpGRF(1-29)-NH2]

D. Coy, V. Lance, W. Murphy, 1985 .

Pituitary adenylate cyclase activating peptide receptors regulate the growth of non-small cell lung cancer cells.

T. Moody, D. Coy, S. Wank, 1995, Cancer research.

(D-Ala 6, Des-Gly-NH 2 10)-LH-RH-ethylamide: a new analogue with unusually high LH-RH-FSH-RH activity.

A. Schally, D. Coy, A. Arimura, 1974, Endocrinology.

Blockage of ovulation in rats by inhibitory analogs of luteinizing hormones-releasing hormone.

D. Coy, A. Arimura, J. Vilchez-Martinez, 1976, Science.

Suppression of gonadotropin release and ovulation in animals by inhibitory analogs of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, A. Arimura, 1976, Current topics in molecular endocrinology.

STIMULATION OF LUTEINISING HORMONE (L.H.) RELEASE AFTER ORAL ADMINISTRATION OF AN ANALOGUE OF L.H. RELEASING HORMONE

A. Kastin, D. Coy, M. C. Miller, 1975, The Lancet.

Anti-Luteinizing Hormone (LH)-Releasing Activity of Several Analogues of LH-Releasing Hormone

A. Schally, D. Coy, A. Arimura, 1975 .

Polyfluoroalkylamine derivatives of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, A. Arimura, 1975, Biochemistry.

Structure-Activity Relationship of LH and FSH Releasing Hormone

A. Schally, D. Coy, E. Coy, 1975 .

Control of gonadotrophic hormone release in trout: influence of synthetic LH-RH and LH-RH analogues in vivo and in vitro.

A. Schally, D. Coy, D. M. Evans, 1981, Life sciences.

Solid phase synthesis of growth hormone-release inhibiting factor.

A. Schally, D. Coy, A. Arimura, 1973, Biochemical and biophysical research communications.

Isolation, structure, biological characterization, and synthesis of beta-[Tyr9]melanotropin-(9-18) decapeptide from pig hypothalami.

A. Kastin, A. Schally, D. Coy, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The antigenic determinant of the LH-releasing hormone for three different antisera.

A. Schally, D. Coy, A. Arimura, 1975, Acta endocrinologica.

Structure — Function of LH-RH Analogs and Design Applications to other Peptide Systems

D. Coy, M. Nekola, 1984 .

LHRH antagonists in females

D. Coy, M. Nekola, 1984 .

Suppression of the positive feedback of estradiol benzoate on gonadotropin secretion by an inhibitory analog of luteinizing hormone-releasing hormone (LRH) in oophorectomized rhesus monkeys: evidence for a necessary synergism between LRH and estrogens.

A. Schally, D. Coy, J. Balmaceda, 1983, The Journal of clinical endocrinology and metabolism.

Suppression of ovulation in the rat by an orally active antagonist of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, L. Ge, 1982, Science.

Effects of in vivo treatment with an LHRH antagonist analog (D-PHE2-D-PHE6) in the immature male rat.

A. Schally, D. Coy, A. Steinberger, 1978, Biology of reproduction.

An in vivo assay for anti-LH-RH and anti-FSH-RH activity of inhibitory analogues of LH-RH.

A. Schally, D. Coy, A. Arimura, 1975, Endocrinology.

10 lH RH antagonists in females

D. Coy, M. Nekola, 1984 .

Blockade of the Pre-ovulatory LH Surge in Hamsters by an Inhibitory Analog of LH-RH 1

A. Schally, D. Coy, A. Arimura, 1975 .

Synthesis and biological properties of (Leu-6)-LH-RH and (D-Leu-6,desGly-NH210)-LH-RH ethylamide.

A. Schally, D. Coy, A. Arimura, 1974, Biochemical and biophysical research communications.

In vitro inhibition of LH release by a synthetic antagonist of LH-releasing hormone (LH-RH).

A. Schally, D. Coy, A. Arimura, 1974, Endocrinology.

Development of a method to test anti-LH-RH activity in rats.

A. Schally, D. Coy, A. Arimura, 1974, Neuroendocrinology.

Prolonged elevation of luteinizing hormone (LH) after intranasal administration of an analog of LH-releasing hormone.

A. Kastin, A. Schally, D. Coy, 1976, Fertility and sterility.

The Effect of Oral and Vaginal Administration of Synthetic LH-RH and [D-ALA6, DES GLY10-NH2]-LH-RH Ethylamide on Serum LH Levels in Ovariectomized, Steroid Blocked Rats 1

A. Schally, D. Coy, A. Arimura, 1975, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Investigation of the role of tryptophan in the luteinizing hormone-releasing hormone.

A. Schally, D. Coy, G. I. Tesser, 1974, Biochemistry.

A peptide inhibitor of luteinizing hormone-releasing hormone (LH-RH).

A. Schally, D. Coy, A. Arimura, 1973, The Journal of clinical endocrinology and metabolism.

Synthesis and biological activity of LH-RH analogs modified at the carboxyl terminus.

A. Schally, D. Coy, E. Coy, 1975, Journal of medicinal chemistry.

Lack of growth hormone-releasing activity of (pyro)Glu-Ser-Gly-NH2.

J. Takahara, A. Schally, D. Coy, 1973, Biochemical and biophysical research communications.

Effect of simple amino acid replacements on the biological activity of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, E. Coy, 1973, Journal of medicinal chemistry.

Luteinizing hormone releasing hormone. Solid-phase synthesis of a 5-phenylalanine analog possessing high biological activity.

A. Schally, D. Coy, E. Coy, 1973, Journal of medicinal chemistry.

Synthesis and biological properties of ovine corticotropin-releasing factor (CRF).

I. Torres-Aleman, A. Schally, D. Coy, 1982, Life sciences.

Synthesis of luteinizing hormone-releasing hormone containing tritium-labelled pyroglutamic acid.

A. Schally, D. Coy, E. Coy, 1973, Biochemical and biophysical research communications.

Dynorphin immunocytochemistry in the rat central nervous system

M. E. Lewis, H. Akil, S. Watson, 1982, Peptides.

Effects of endorphin and enkephalin analogs on fear habituation in goldfish

R. Olson, A. Kastin, D. Coy, 1978, Pharmacology Biochemistry and Behavior.

[D-Ala2,(F5)Phe4]-dynorphin1–13-NH2 (DAFPHEDYN): A potent analog of dynorphin 1–13

H. Akil, W. Bowen, E. Young, 1987, Peptides.

Role of Different Bombesin Receptor Subtypes Mediating Contractile Activity in Cat Upper Gastrointestinal Tract

E. Vizi, D. Coy, M. Papasova, 1998, Peptides.

Somatostatin Receptor-mediated Signaling in Smooth Muscle ACTIVATION OF PHOSPHOLIPASE C- 3 BY G AND INHIBITION OF ADENYLYL CYCLASE BY G AND G o

G. Makhlouf, D. Coy, K. Murthy, 1996 .

Partial agonist activity of the bombesin-receptor antagonist [Leu14-psi-CH2-NH-Leu13]-bombesin in frog peptic cells.

K. Dickinson, D. Coy, B. Hirschowitz, 1988, Biochemical and biophysical research communications.

GRP-preferring bombesin receptor subtype mediates contractile activity in cat terminal ileum

E. Vizi, D. Coy, G. Varga, 1994, Peptides.

Responses to human CGRP, ADM, and PAMP in human thymic arteries.

D. Coy, T. Bivalacqua, H. Champion, 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

Modulation of secretin release by neuropeptides in secretin-producing cells.

D. Coy, W. Chey, Ta-min Chang, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR 4‐2J

L. Buscail, D. Coy, A. Arimura, 1990, FEBS letters.

Antitumor and antiangiogenic effects of somatostatin receptor-targeted in situ radiation with (111)In-DTPA-JIC 2DL.

J. Fuselier, D. Coy, E. Woltering, 2001, The Journal of surgical research.

Interaction of vasoactive intestinal peptide (VIP) and N-terminally modified VIP analogs with rat pancreatic, hepatic and pituitary membranes.

D. Coy, P. de Neef, P. Robberecht, 1986, European journal of biochemistry.

[D-Phe4]peptide histidine-isoleucinamide ([D-Phe4]PHI), a highly selective vasoactive-intestinal-peptide (VIP) agonist, discriminates VIP-preferring from secretin-preferring receptors in rat pancreatic membranes.

D. Coy, P. de Neef, P. Robberecht, 1987, European journal of biochemistry.

Comparative structural requirements of thirty GRF analogs for interaction with GRF- and VIP receptors and coupling to adenylate cyclase in rat adenopituitary, liver and pancreas

D. Coy, P. Robberecht, J. Christophe, 1986, Peptides.

Specific labelling of high-affinity vasoactive intestinal peptide receptors in rat liver membranes by a growth hormone-releasing factor analog.

D. Coy, P. de Neef, P. Robberecht, 1986, Neuroendocrinology.

Comparative structural requirements of GRF analogs for occupancy of GRF and VIP receptors and coupling to adenylate cyclase in rat adenopituitary, liver and pancreas

D. Coy, P. Robberecht, J. Christophe, 1985, Regulatory Peptides.

Inhibition of pancreatic secretion by enkephalin and morphine in dogs.

D. Coy, S. Konturek, J. Jaworek, 1978, Gastroenterology.

Targeted Chemotherapy Using a Cytotoxic Somatostatin Conjugate to Inhibit Tumor Growth and Metastasis in Nude Mice

J. Fuselier, D. Coy, Lichun Sun, 2008, Clinical medicine. Oncology.

Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP).

R. Jensen, D. Coy, K. Tokita, 2005, Biochemical pharmacology.

Behavioral effects after systemic injection of opiate peptides

R. Olson, A. Kastin, D. Coy, 1980, Psychoneuroendocrinology.

The Wound Dressings and Their Applications in Wound Healing and Management

Quan-yong He, D. Coy, Lichun Sun, 2019 .

Systemic administration of a novel octapeptide, amylin-(1---8), increases bone volume in male mice.

I. Reid, J. Cornish, K. Callon, 2000, American journal of physiology. Endocrinology and metabolism.

Radioimmunoassay of DSIP-like material in human blood: Possible protein binding

W. Banks, A. Kastin, D. Coy, 1981, Pharmacology Biochemistry and Behavior.

The effect of beta-(Tyr9)melanotropin-(9-18) on the active avoidance and open-field behavior on rats pretreated with atropine or propranolol.

L. Vécsei, A. Schally, D. Coy, 1984, Pharmacological research communications.

Behavioural Modulation by Systemic Administration of Enkephalins and Endorphins

R. Olson, A. Kastin, D. Coy, 1981 .

The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling

D. Coy, Lichun Sun, Cuiyun Yu, 2015, Journal of Cancer.

Valproic acid suppresses cervical cancer tumor progression possibly via activating Notch1 signaling and enhances receptor-targeted cancer chemotherapeutic via activating somatostatin receptor type II

J. Fuselier, D. Coy, Lichun Sun, 2013, Archives of Gynecology and Obstetrics.

Receptor occupancy and adenylate cyclase activation in rat liver and heart membranes by 10 glucagon analogs modified in position 2, 3, 4, 25, 27 and/or 29

D. Coy, L. Moroder, P. Robberecht, 1988, Regulatory Peptides.

Somatostatin analogs which inhibit glucagon and growth hormone more than insulin release.

J. Drouin, A. Schally, D. Coy, 1977, Biochemical and biophysical research communications.

Convenient apparatus for preparative polyacrylamide gel electrophoresis and its use in purification of three porcine neurophysins.

D. Coy, T. Wuu, 1971, Analytical biochemistry.

Inhibition of bombesin-stimulated gastrin release from isolated canine G cells by bombesin antagonists.

R. Pederson, C. Mcintosh, D. Coy, 1989, Canadian journal of physiology and pharmacology.

Cranial irradiation for cerebral and nasopharyngeal tumours in children: evidence for the production of a hypothalamic defect in growth hormone release.

A. Grossman, M. Savage, D. Coy, 1986, The Journal of endocrinology.

[D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists.

R. Jensen, D. Coy, J. Gardner, 1987, The American journal of physiology.

Stimulation of growth hormone by vasoactive intestinal polypeptide in acromegaly.

H. Kaji, D. Coy, T. Fujita, 1984, The Journal of clinical endocrinology and metabolism.

Comparison of Somatuline (BIM‐23014) and somatostatin on endocrine and exocrine activities in the rat

D. Coy, W. Murphy, S. Moreau, 1991 .

Synthesis of camptothecin–amino acid carbamate linkers

J. Fuselier, D. Coy, M. Etienne, 2012, Amino Acids.

Differential binding of somatostatin agonists to somatostatin receptors in brain and adenohypophysis.

D. Coy, M. Heiman, W. Murphy, 1987, Neuroendocrinology.

Camptothecin-somatostatin conjugates inhibit the growth of small cell lung cancer cells

R. Jensen, T. Moody, J. Fuselier, 2005, Peptides.

STUDY OF INHIBITORY EFFECTS OF AN ANTIANGIOGENIC SOMATOSTATIN-CAMPTOTHECIN CONJUGATE ON LASER-INDUCED CHOROIDAL NEOVASCULARIZATION IN RATS

J. Fuselier, D. Coy, G. Peyman, 2005, Retina.

Effects of Camptothecin Conjugated to a Somatostatin Analog Vector on Growth of Tumor Cell Lines in Culture and Related Tumors in Rodents

J. Fuselier, D. Coy, Lichun Sun, 2004, Drug delivery.

An adjustable release rate linking strategy for cytotoxin-peptide conjugates.

J. Fuselier, D. Coy, Lichun Sun, 2003, Bioorganic & medicinal chemistry letters.

Rational Design of a Peptide Agonist That Interacts Selectively with the Orphan Receptor, Bombesin Receptor Subtype 3*

R. Jensen, D. Coy, S. Hocart, 2001, The Journal of Biological Chemistry.

Effects of a superactive analogue of LH-RH on the hypothalamo-pituitary-testicular axis in male rats pretreated with estrogens.

A. Schally, D. Coy, V. Rettori, 1981, Archives of andrology.

Reduction of LH-RH pituitary and estradiol uterine binding sites by a superactive analog of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, A. Arimura, 1980, Biochemical and biophysical research communications.

Clinical studies with d-TRP6-luteinizing hormone-releasing hormone in men with hypogonadotropic hypogonadism.

A. Schally, D. Coy, A. Fernandez-cruz, 1978, Fertility and sterility.

Pharmacology of Growth Hormone-Releasing Hormone and Its Peptide Analogs

D. Coy, 2000 .

Pharmacokinetic evaluation of superactive analogues of growth hormone-releasing factor (1–29)-amide

D. Coy, S. Poole, B. Rafferty, 1988, Peptides.

Growth hormone releasing factor: comparison of two analogues and demonstration of hypothalamic defect in growth hormone release after radiotherapy.

A. Grossman, M. Savage, D. Coy, 1984, British medical journal.

The Pathogenesis and Therapeutics of Nasopharyngeal Carcinoma

Quan-yong He, D. Coy, Lichun Sun, 2019 .

The somatostatin receptor subtype on rat enterochromaffinlike cells.

G. Sachs, C. Prinz, D. Coy, 1994, Gastroenterology.

Tyrosine 220 in the 5th Transmembrane Domain of the Neuromedin B Receptor Is Critical for the High Selectivity of the Peptoid Antagonist PD168368*

David H. Coy, R. Jensen, D. Coy, 2001, The Journal of Biological Chemistry.

Somatostatin receptor subtype 3 mediates the inhibitory action of somatostatin on gastric smooth muscle cells.

D. Coy, V. Corleto, S. Mantey, 1995, The American journal of physiology.

Endogenous Opiate Systems May Modulate Learning and Memory

R. Olson, A. Kastin, D. Coy, 1984 .

Potent inhibitory effects of a type four receptor-selective somatostatin analog on rat insulin release.

D. Coy, W. Rossowski, 1993, Biochemical and Biophysical Research Communications - BBRC.

Effects of an LHRH antagonist on the time of occurrence and amplitude of the preovulatory LH surge, progesterone and estradiol secretion, and ovulation in superovulated Holstein heifers.

D. Coy, J. Walton, N. Rawlings, 1994, Theriogenology.

Activation of neuromedin B-preferring bombesin receptors on rat glioblastoma C-6 cells increases cellular Ca2+ and phosphoinositides.

R. Jensen, L. Wang, D. Coy, 1992, The Biochemical journal.

[Leu13-ψ(CH2NH)Leu14]bombesin is a specific bombesin receptor antagonist in Swiss 3T3 cells

P. Woll, E. Rozengurt, D. Coy, 1988 .

Chief cells possess somatostatin receptors regulated by secretagogues acting through the calcium or cAMP pathway.

R. Jensen, D. Coy, C. Felley, 1994, The American journal of physiology.

Blockade of bombesin receptors with [Leu14-ψ(CH2NH)-Leu13]bombesin fails to suppress nutrient-induced CCK release from rat duodenojejunum

D. Coy, J. Chayvialle, J. Cuber, 1990, Peptides.

Pituitary adenylate cyclase-activating polypeptide (PACAP) protects against mitoxantrone-induced cardiac injury in mice

D. Coy, K. Varner, H. Xia, 2017, Peptides.

Pituitary adenylate cyclase-activating peptide stimulates rat pancreatic secretion via secretin and cholecystokinin releases.

D. Coy, W. Chey, K. Lee, 1998, Gastroenterology.

LH-RH antagonist inhibits gonadal steroid secretion in vitro

D. Coy, J. Spona, E. Zatlasch, 1985, Peptides.

PACAP(6-38) inhibits the growth of prostate cancer cells.

T. Moody, M. Birrer, D. Coy, 1998, Cancer letters.

PACAP (6–38) is a PACAP receptor antagonist for breast cancer cells

T. Moody, D. Coy, J. Pisegna, 1999, Breast Cancer Research and Treatment.

[Psi13,14] Bombesin Analogues Inhibit Growth of Small Cell Lung Cancer in Vitro and in Vivo

T. Moody, J. Staley, J. Mulshine, 1991 .

Blockade of feeding inhibition by neuromedin B using a selective receptor antagonist.

J. Taylor, D. Coy, T. Moran, 1994, European journal of pharmacology.

Pharmacological characterization of [Leu-13-psi-CH2NH-Leu14]-bombesin as a specific bombesin receptor antagonist on isolated smooth muscle cells.

R. Jensen, G. delle Fave, D. Coy, 1989, The Journal of pharmacology and experimental therapeutics.

Administration of luteinizing hormone-releasing hormone analogs delays ovulation without affecting the luteal function in rhesus monkeys.

A. Schally, D. Coy, J. Balmaceda, 1983, Fertility and sterility.

GI side-effects of a possible therapeutic GRF analogue in monkeys are likely due to VIP receptor agonist activity

R. Jensen, D. Coy, Tetsuhide Ito, 2001, Peptides.

Rat melanin concentrating hormone does not modify the release of CRH-41 from rat hypothalamus or ACTH from the anterior pituitary in vitro.

A. Grossman, D. Coy, G. Besser, 1990, The Journal of endocrinology.

Thermoregulatory and locomotor effects of DSIP: Paradoxical interaction with d-amphetamine

A. Kastin, D. Coy, S. Yehuda, 1980, Pharmacology Biochemistry and Behavior.

D-amphetamine-induced hypothermia and hypermotility in rats: Changes after systemic administration of beta-endorphin

A. Kastin, D. Coy, S. Yehuda, 1980, Peptides.

Brain beta-endorphin-like immunoreactivity in adult rats given beta-endorphin neonatally.

C. Sandman, A. Kastin, D. Coy, 1981, Brain research bulletin.

Opposite effects of CRF and ACTH on reserpine-induced hypothermia

A. Kastin, D. Coy, J. Sueiras-diaz, 1982, Pharmacology Biochemistry and Behavior.

Central Nervous System Effects after Systemic Injection of Opiate Peptides

R. Olson, A. Kastin, D. Coy, 1982 .

Sleep-wave activity of a delta sleep-inducing peptide analog correlates with its penetrance of the blood-brain barrier.

L. H. Miller, A. Kastin, D. Coy, 1986, Sleep.

DSIP reduces amphetamine-induced hyperthermia in mice

A. Kastin, D. Coy, J. Zadina, 1984, Physiology & Behavior.

DSIP — more than a sleep peptide?

A. Kastin, A. Schally, D. Coy, 1980, Trends in Neurosciences.

Radioimmunoassay of DSIP-like material in rat brain

A. Kastin, A. Schally, D. Coy, 1978, Brain Research Bulletin.

Effect of substance P/bombesin antagonists on the release of growth hormone by GHRP and GHRH.

D. Coy, C. Bowers, K. Bitar, 1991, Biochemical and biophysical research communications.

Pituitary adenylate cyclase-activating polypeptide stimulates cholecystokinin secretion in STC-1 cells.

C. Chang, D. Coy, W. Chey, 1996, The American journal of physiology.

Polyfluoroalkyl derivatives of nitrogen. Part XL. Reaction of trifluoronitrosomethane with NN-bistrifluoromethylamino-substituted allenes

D. Coy, M. Newlands, A. E. Tipping, 1973 .

Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

M. Vranic, M. Riddell, D. Coy, 2013, Diabetes.

Comparative efficacy of seven synthetic glucagon analogs, modified in position 1, 2 and/or 12, on liver and heart adenylate cyclase from rat

D. Coy, P. Robberecht, J. Christophe, 1986, Peptides.

Facilitation of sexual receptivity in the rat by an ovulation-inhibiting analog of LHRH

A. Kastin, D. Coy, J. Zadina, 1981, Pharmacology Biochemistry and Behavior.

Endorphin analogs with potent and long-lasting analgesic effects

C. Sandman, A. Kastin, D. Coy, 1977, Pharmacology Biochemistry and Behavior.

Solid-phase synthesis and biological activities of gastrointestinal hormones: Secretin and motilin

D. Coy, W. Chey, E. Coy, 1982, Peptides.

Human growth hormone-releasing hormone analogues with much improved in vitro growth hormone-releasing potencies in rat pituitary cells.

D. Coy, S. Hocart, W. Murphy, 1991, European journal of pharmacology.

Peptide antagonists of LH-RH: large increases in antiovulatory activities produced by basic D-amino acids in the six position.

A. Schally, D. Coy, J. Érchegyi, 1982, Endocrinology.

An in vivo model for testing inhibition of arginine-induced insulin and glucagon release by somatostatin analogs.

A. Schally, D. Coy, A. Arimura, 1977, Acta endocrinologica.

Pituitary adenylate cyclase-activating polypeptide relaxes rat gastrointestinal smooth muscle.

D. Coy, A. Arimura, Z. Mungan, 1992, Scandinavian journal of gastroenterology.

Expression of somatostatin receptor genes and their role in inhibiting Cl- secretion in HT-29cl.19A colonocytes.

G. Warhurst, D. Coy, M. Lewin, 1995, The American journal of physiology.

Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle.

R. Jensen, D. Coy, T. Pradhan, 1993, The Journal of pharmacology and experimental therapeutics.

The disappearance, excretion, and metabolism of tritiated prolyl-leucyl-glycinamide in man.

A. Kastin, A. Schally, D. Coy, 1974, Neuroendocrinology.

Effect of somatostatin on myoelectrical activity of small bowel.

A. Schally, D. Coy, S. Konturek, 1978, The American journal of physiology.

Superactive amidated COOH-terminal glucagon analogues with no methionine or tryptophan

D. Coy, V. Lance, W. Murphy, 1986, Peptides.

HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II.

J. Chen, Quan-yong He, D. Coy, 2018, American journal of translational research.

Notch Signaling Activation in Cervical Cancer Cells Induces Cell Growth Arrest with the Involvement of the Nuclear Receptor NR4A2

D. Coy, Lichun Sun, Qingqing Qian, 2016, Journal of Cancer.

Editorial: GPCR-Targeted Drug Development.

D. Coy, Lichun Sun, 2016, Current Drug Targets.

Is Notch Signaling a Specific Target in Hepatocellular Carcinoma?

D. Coy, Lichun Sun, Yan Yu, 2015, Anti-cancer agents in medicinal chemistry.

The effects of β-(TYR9)melanotropin-(9–18) and H-PHE-ILE-TYR-HIS-SER-TYR-LYS-OH on the analgesic action of morphine

L. Vécsei, A. Schally, D. Coy, 1983, Neuropharmacology.

Effects of β-/Tyr9/melanotropin-/9–18/ decapeptide on catecholamine disappearance and serotonin accumulation in discrete brain regions of rats

A. Schally, D. Coy, G. Telegdy, 1981, Neuropeptides.

Effects of CRF-like heptapeptide on catecholamine disappearance and serotonin accumulation in different brain areas of rats

A. Schally, D. Coy, G. Telegdy, 1982, Neuropeptides.

Isolation, structure and synthesis of a heptapeptide with in vitro ACTH-releasing activity from porcine hypothalamus.

A. Schally, D. Coy, A. Arimura, 1981, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on the in vitro uptake and release of radiolabelled dopamine, noradrenaline and serotonin in rat brain hypothalamic slices

L. Vécsei, A. Schally, D. Coy, 1984, Neuropeptides.

Colonic smooth muscle cells possess a different subtype of somatostatin receptor from gastric smooth muscle cells.

R. Jensen, G. delle Fave, D. Coy, 1997, The American journal of physiology.

Effect of somatostatin on gastrointestinal secretions and peptic ulcer production in cats.

A. Schally, D. Coy, S. Konturek, 1977, Scandinavian journal of gastroenterology.

Comparison of methionine-enkephalin and morphine in the stimulation of gastric acid secretion in the dog.

A. Schally, D. Coy, S. Konturek, 1980, Gastroenterology.

Effects of anorexigenic peptide on gastric and pancreatic secretion.

D. Coy, S. Konturek, J. Jaworek, 1981, The Journal of physiology.

Systemic injections of gastro-intestinal peptides alter behavior in rats

R. Olson, A. Kastin, D. Coy, 1980, Peptides.

Proceedings: Investigation and treatment of a recurrent vipoma.

J. Polak, A. Kastin, A. Schally, 1975, Gut.

Galanin-induced relaxation in gastric smooth muscle cells is mediated by cyclic AMP

R. Jensen, D. Coy, T. Pradhan, 1994, Peptides.

Multiply radioiodinated somatostatin analogs induce receptor-specific cytotoxicity.

J. Fuselier, D. Coy, E. Woltering, 1998, The Journal of surgical research.

Structure-activity relationships for relaxation of smooth muscle by VIP

D. Coy, O. Rorstad, H. Shirahase, 1994, Peptides.

Permeability of blood-brain barrier to DSIP peptides

A. Kastin, D. Coy, C. Nissen, 1981, Pharmacology Biochemistry and Behavior.

DSIP-like immunoreactivity in the developing rat brain

A. Kastin, D. Coy, C. Nissen, 1981, Brain Research Bulletin.

Inverse relationship between onset and duration of EEG effects of six peripherally administered peptides

L. H. Miller, A. Kastin, D. Coy, 1981, Pharmacology Biochemistry and Behavior.

Delta-sleep-inducing peptide reduces CRF-induced corticosterone release.

A. Kastin, D. Coy, A. Fischman, 1985, Neuroendocrinology.

Tyrosine 220 in the 5 th Transmembrane Domain of the Neuromedin B Receptor Is Critical for the High Selectivity of the Peptoid Antagonist PD 168368 *

R. Jensen, D. Coy, K. Tokita, 2000 .

Regulation of acid secretion by bombesin/GRP neurons of the gastric fundus.

G. Makhlouf, D. Coy, M. Schubert, 1991, The American journal of physiology.

Pituitary adenylate cyclase-activating polypeptide prevents contrast-induced nephropathy in a novel mouse model

V. Batuman, D. Coy, Min Li, 2013, Physiological reports.

Levels of luteinizing hormone (LH), follicle-stimulating hormone, and 17 beta-estradiol in response to D-Trp6-LH-releasing hormone during different phases of the menstrual cycle in normal women.

A. Schally, D. Coy, C. Jaramillo, 1978, Fertility and sterility.

Is the postovulatory release of follicle-stimulating hormone in the rabbit mediated by luteinizing hormone-releasing hormone?

J. Copland, A. Schally, D. Coy, 1983, Endocrinology.

Serum LH, FSH and testosterone response to the administration of a new LH-RH analog, D-Trp6-LH-RH, in normal men.

A. Schally, D. Coy, V. Perez-Infante, 1977, International journal of fertility.

An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha.

J. Kolls, A. Cheung, D. Ree, 1998, Endocrinology.

Investigation of cancer cell lines for peptide receptor-targeted drug development

D. Coy, Lichun Sun, K. LePage, 2011, Journal of drug targeting.

The molecular basis for high affinity of a universal ligand for human bombesin receptor (BnR) family members.

R. Jensen, D. Coy, S. Hocart, 2012, Biochemical pharmacology.

Three-dimensional quantitative structure-activity relationships of somatostatin analogues. 1. Comparative molecular field analysis of growth hormone release-inhibiting potencies.

D. Coy, S. Hocart, W. Murphy, 1995, Journal of medicinal chemistry.

Distribution of radioactivity in the organs of the rat and mouse after injection of L-(3H)prolyl-L-leucyl-glycinamide.

A. Kastin, A. Schally, D. Coy, 1975, The Journal of endocrinology.

Progress in the development of competitive bombesin antagonists

R. Jensen, D. Coy, N. Jiang, 1987, Regulatory Peptides.

(D‐Phe12) bombesin and substance P analogues function as central bombesin receptor antagonists

J. Crawley, R. Jensen, D. Coy, 1988, Synapse.

Autoradiographic localization of neuromedin B binding sites in rat brain

R. Jensen, T. Moody, D. Coy, 1990, Molecular and Cellular Neuroscience.

Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction.

D. Coy, J. Holst, B. Schjoldager, 1991, The American journal of physiology.

Solid-phase synthesis and biological properties of psi [CH2NH] pseudopeptide analogues of a highly potent somatostatin octapeptide.

D. Coy, M. Heiman, Y. Sasaki, 1987, Journal of medicinal chemistry.

Effect of reductive alkylation of lysine in positions 6 and/or 8 on the histamine-releasing activity of luteinizing hormone-releasing hormone antagonists.

D. Coy, S. Hocart, M. Nekola, 1987, Journal of medicinal chemistry.

Carrier-mediated transport of enkephalins and N-Tyr-MIF-1 across blood-brain barrier.

W. Banks, A. Kastin, D. Coy, 1986, The American journal of physiology.

Entry of DSIP peptides into dog CSF: Role of physicochemical and pharmacokinetic parameters

W. Banks, A. Kastin, D. Coy, 1986, Brain Research Bulletin.

Prostate carcinoma tumor size in rats decreases after administration of antagonists of luteinizing hormone-releasing hormone.

A. Schally, D. Coy, T. Redding, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Physiological, veterinary and clinical effects of hypothalamic releasing hormones (RH), especially LH-RH

A. Kastin, A. Schally, W. König, 1974 .

MIF-I and postsynaptic receptor sites for dopamine

F. Bymaster, A. Kastin, D. Coy, 1979, Brain Research Bulletin.

Bombesin receptor antagonists differentiate receptor subtypes in rat brain.

R. Jensen, J. Taylor, D. Coy, 1993, European journal of pharmacology.

Effect of [(CH2NH)4,5]secretin on pancreatic exocrine secretion in guinea pigs and rats.

D. Coy, W. Chey, K. Lee, 1993, American Journal of Physiology.

Distinct receptors mediate gastrin-releasing peptide and neuromedin B-induced delay of gastric emptying of liquids in rats

D. Coy, C. Scarpignato, G. Varga, 1995 .

Peptide structural requirements for antagonism differ between the two mammalian bombesin receptor subtypes.

R. Jensen, D. Coy, S. Mantey, 1995, The Journal of pharmacology and experimental therapeutics.

Neuromedin B binds with high affinity, elevates cytosolic calcium and stimulates the growth of small-cell lung cancer cell lines.

R. Jensen, T. Moody, J. Staley, 1992, The Journal of pharmacology and experimental therapeutics.

Distinguishing bombesin receptor subtypes using the oocyte assay.

R. Jensen, D. Coy, H. Shapira, 1991, Biochemical and biophysical research communications.

Solubilization and purification of bombesin/gastrin releasing peptide receptors from human cell lines

R. Jensen, T. Moody, J. Staley, 2007, Journal of Molecular Neuroscience.

[Des-Met14]Bombesin analogues function as small cell lung cancer bombesin receptor antagonists

J. Staley, J. Taylor, D. Coy, 1991, Peptides.

[Psi 13,14] bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo.

T. Moody, J. Staley, J. Mulshine, 1991, Cancer research.

Structure-activity studies of antagonists of luteinizing hormone-releasing hormone with emphasis on the amino-terminal region.

D. Coy, S. Hocart, M. Nekola, 1987, Journal of medicinal chemistry.

Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors

J. Fuselier, D. Coy, Lichun Sun, 2002, Peptides.

Effects of a novel bombesin antagonist analogue on bombesin-stimulated gastric acid secretion and growth hormone release in the pentobarbital-anesthetized rat.

D. Coy, W. Murphy, W. Rossowski, 1989, Scandinavian journal of gastroenterology.

Possible recognition of the GnRH receptor by an antiserum against a peptide encoded by nucleotide sequence complementary to mRNA of a GnRH precursor peptide

T. Görcs, D. Coy, A. Arimura, 1986, Peptides.

Bombesin-like peptides stimulate somatostatin release from rat fundic D cells in primary culture.

D. Coy, M. Classen, J. Walsh, 1997, American Journal of Physiology.

STIMULATION OF GROWTH HORMONE AND PROLACTIN RELEASE BY MORPHINE AND OPIATE-LIKE PEPTIDES

Choh Hao Li, A. Schally, D. Coy, 1978 .

Effects of MIF-1 and three related peptides on reserpine-induced hypothermia in mice

A. Kastin, D. Coy, L. C. Honour, 1981, Pharmacology Biochemistry and Behavior.

Peptides and the Blood-Brain Barrier

R. Olson, A. Kastin, A. Schally, 1980 .

Kyotorphins affect aversive pecking in chicks

A. Kastin, D. Coy, L. C. Honour, 1981, Physiology & Behavior.

Bombesin stimulates adhesion, spreading, lamellipodia formation, and proliferation in the human colon carcinoma Isreco1 cell line.

J. Saurin, D. Coy, J. Chayvialle, 1999, Cancer research.

Gastrin releasing peptide-preferring bombesin binding sites in human lung.

D. Coy, J. Gies, Y. Landry, 1994, European journal of pharmacology.

First neuromedin B receptor antagonists are based on somatostatin octapeptide analogues

R. Jensen, D. Coy, John E. Taylor, 1994 .

Conformational scan of bombesin/GRP reveals new position 11 receptor antagonists

R. Jensen, D. Coy, M. Neya, 1994 .

Receptors for mammalian bombesin/GRP and neuromedin B have greatly differing ligand binding requirements

R. Jensen, D. Coy, N. Jiang, 1992 .

Cyclic Bombesin/GRP Analogs Which Retain Either Agonist or Antagonist Activity,

D. Coy, J. Moreau, S. Kim, 1992 .

Bombesin stimulates invasion and migration of lsreco1 colorecial cancer cells in a Rho-dependent manner

J. Saurin, D. Coy, J. Chayvialle, 2001 .

[Phe4]somatostatin: a potent, selective inhibitor of growth hormone release.

A. Schally, D. Coy, A. Arimura, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Peptone stimulates gastrin secretion from the stomach by activating bombesin/GRP and cholinergic neurons.

G. Makhlouf, D. Coy, M. Schubert, 1992, The American journal of physiology.

Structure-activity studies with somatostatin: role of lysine in positions 4 and 9 for gastric activity

B. Hirst, D. Coy, 1984, Regulatory Peptides.

Inhibition of the release of growth hormone in vitro by -melanocyte stimulating hormone.

J. Takahara, A. Kastin, A. Schally, 1973, Biochemical and biophysical research communications.

Possible non-narcotic component to action of opiate peptides on tonic immobility

R. Olson, G. Lahoste, A. Kastin, 1979, Pharmacology Biochemistry and Behavior.

Effects of an enkephalin analog on complex learning in the rhesus monkey

R. Olson, A. Kastin, D. Coy, 1979, Pharmacology Biochemistry and Behavior.

Behavioral effects of D-Ala2-β-endorphin in squirrel monkeys

M. Kneale, R. Olson, F. Castellanos, 1978, Pharmacology Biochemistry and Behavior.

Cyclic hexa- and pentapeptide somatostatin analogues with reduced gastric inhibitory activity

B. Hirst, D. Coy, E. Arilla, 1984, Peptides.

Position 4 substituted somatostatin analogs: increased binding to somatostatin receptors in pituitary and brain.

D. Coy, C. B. Srikant, Y. Patel, 1983, Life sciences.

Attempts to programme ovulation with exogenous oestrogens and LH-RH analogue.

A. Schally, D. Coy, H. Croxatto, 1975, British medical journal.

Synthesis and biological properties of the 2-L-beta-(pyrazolyl-1)alanine analogs of luteinizing hormone-releasing hormone and thyrotropin-releasing hormone.

A. Schally, D. Coy, E. Coy, 1975, Journal of medicinal chemistry.

Activity of VIP, somatostatin and other peptides in the mouse vas deferens assay

A. Kastin, A. Schally, D. Coy, 1978, Pharmacology Biochemistry and Behavior.

CNS ACTIONS OF PERIPHERALLY ADMINISTERED PEPTIDES: SOME UNRESOLVED ISSUES

R. Olson, C. Sandman, A. Kastin, 1982 .

Cyclic lactam analogues of ovine pituitary adenylate cyclase activating polypeptide (PACAP): Discovery of potent type II receptor antagonists

D. Coy, A. Somogyvári-Vigh, K. Bitar, 1994, Peptides.

Systemic administration of adrenomedullin(27-52) increases bone volume and strength in male mice.

I. Reid, J. Cornish, K. Callon, 2001, The Journal of endocrinology.

Basic and clinical studies with luteinizing hormone-releasing hormone (LH-RH) and its analogues.

A. Kastin, A. Schally, D. Coy, 1973, Journal of reproduction and fertility. Supplement.

Effect of D-Trp6-LH-RH on the pituitary-gonadal axis during the luteal phase in the baboon.

A. Schally, D. Coy, A. Arimura, 1979, Acta endocrinologica.

Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats

M. Vranic, M. Riddell, D. Coy, 2013, Diabetes.

Smooth muscle cells from guinea pig stomach possess high-affinity galanin receptors that mediate relaxation.

R. Jensen, D. Coy, T. Pradhan, 1994, American Journal of Physiology.

Effect of enkephalin and naloxone on gastric acid and serum gastrin and pancreatic polypeptide concentrations in humans.

D. Coy, S. Konturek, W. Bielański, 1983, Gut.

Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo.

I. Reid, J. Cornish, K. Callon, 1997, The American journal of physiology.

Glp-1 analogue

D. Coy, Z. Dong, コイ，デイヴィッド・エイチ, 1999 .

HETEROGENEITY OF HUMAN GROWTH HORMONE IN PLASMA AND URINE: INFLUENCE OF GROWTH HORMONE RELEASE INHIBITING HORMONE

A. Chait, A. Kastin, A. Schally, 1975 .

Gastrointestinal secretory, motor, circulatory, and metabolic effects of prosomatostatin.

D. Coy, S. Konturek, V. Schusdziarra, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Purification and amino acid composition of constituents of rat neurophysin.

D. Coy, T. Wuu, 1972, Biochimica et biophysica acta.

Production of immunoreactive pituitary adenylate cyclase activating polypeptide (PACAP) by human neuroblastoma cells, IMR-32: detection and characterization with monoclonal and polyclonal antibodies against different epitopes of PACAP.

T. Watanabe, D. Coy, A. Arimura, 1993, Journal of biochemistry.

Inhibition of gastric acid secretion in rat stomach by PACAP is mediated by secretin, somatostatin, and PGE(2).

D. Coy, W. Chey, T. Chang, 2000, American journal of physiology. Gastrointestinal and liver physiology.

Inhibition of gastric acid secretion in rat stomach by PACAP is mediated by secretin, somatostatin, and PGE2

D. Coy, W. Chey, P. Li, 2000 .

Breakdown of enkephalin and endorphin analogs by brain extracts

A. Kastin, D. Coy, A. Grynbaum, 1977, Brain Research Bulletin.

Metabolism of potent enkephalin analogs (FK 33–824, D-Ala2, pentafluorophenylalanine-4-enkephalinamide and a dimer of D-Ala2-enkephalin) and D-amino acid substituted derivatives of human β-endorphin

A. Kastin, D. Coy, N. Marks, 1978, Brain Research Bulletin.

Degradation of delta sleep inducing peptide (DSIP) and its analogs by brain extracts

A. Kastin, D. Coy, N. Marks, 1977, Brain Research Bulletin.

Galanin inhibits cholecystokinin secretion in STC-1 cells.

C. Chang, D. Coy, W. Chey, 1995, Biochemical and biophysical research communications.

Endogenous opiates: 1979(1).

R. Olson, A. Kastin, D. Coy, 1980, Peptides.

Some of the α-NH2-acetylated β-endoprhin-like material in rat and monkey pituitary and brain is acetylated α- and β-endorphin

H. Akil, S. Watson, D. Coy, 1983 .

[35] Solid phase synthesis of luteinizing hormone-releasing hormone and its analogues

A. Schally, D. Coy, E. Coy, 1975 .

Comparison of TRH and anorexigenic peptide on food intake and gastrointestinal secretions

D. Coy, S. Konturek, J. Jaworek, 1981, Peptides.

Conversion of O-Succinimidyl Carbamates to N-(O-Carbamoyl)-succinmonoamides and Ureas: Effects of N-Substituents and Reaction Conditions on the Reaction Pathway.

D. Coy, N. Vasilevich, 2002 .

COMPARISON OF LONG‐ACTING ANALOGUES OF LUTEINIZING HORMONE RELEASING HORMONE IN MAN

A. Kastin, D. Coy, J. Wass, 1979, Clinical endocrinology.

A structure–function study of PACAP using conformationally restricted analogs: Identification of PAC1 receptor-selective PACAP agonists

T. Moody, D. Coy, J. Maderdrut, 2015, Peptides.

Structural Analysis of Ligand Binding Characteristics for the Bombesin/Gastrin-Releasing Peptide Receptor

D. Coy, R. Jensen, 1993 .

Urethane-induced somatostatin mediated inhibition of gastric acid: reversal by the somatostatin 2 receptor antagonist, PRL-2903.

Y. Taché, D. Coy, J. Walsh, 1999, Life sciences.