I. Goldfine

I. Goldfine, M. Goldstein, C. Abraira, 1970, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Nordihydroguaiaretic acid inhibits insulin‐like growth factor signaling, growth, and survival in human neuroblastoma cells

K. Matthay, W. Weiss, J. Youngren, 2007, Journal of cellular biochemistry.

Structural and functional studies of insulin receptors in human breast cancer

R. Vigneri, V. Papa, I. Goldfine, 2004, Breast Cancer Research and Treatment.

Insulin and the regulation of isolated nuclei and nuclear subfractions: potential relationship to mRNA metabolism.

R. Vigneri, F. Purrello, I. Goldfine, 1985, Diabetes/metabolism reviews.

The Effect of Chloroquine on the Binding, Intracellular Distribution, and Action of Insulin on Isolated Mouse Pancreatic Acini

Y. Iwamoto, I. Goldfine, E. Roach, 1983, Diabetes.

Stimulation of the Uptake of α-Aminoisobutyric Acid in Rat Thymocytes by L-Triiodothyronine: A Comparison with Insulin and Dibutyryl Cyclic AMP

I. Goldfine, S. Ingbar, C. G. Simons, 1975 .

Production of antibodies that inhibit the binding of insulin to its receptor.

R. Roth, I. Goldfine, B. Maddux, 1981, Biochemical and biophysical research communications.

Phenformin stimulation of insulin binding to human cultured lymphocytes

Y. Iwamoto, I. Goldfine, 1981, Journal of endocrinological investigation.

Human autoantibodies directed against the human, but not the rat, insulin receptor.

S. Gammeltoft, R. Lauro, L. Rossetti, 1985, The Journal of clinical endocrinology and metabolism.

Effect of amiodarone on L-triiodothyronine stimulation of [3H] thymidine incorporation into GH3 cells

K. Woeber, I. Goldfine, B. Maddux, 1982, Journal of endocrinological investigation.

The CCK receptor on pancreatic plasma membranes: binding characteristics and covalent cross‐linking

C. Sakamoto, I. Goldfine, John A. Williams, 1983, FEBS letters.

Receptors for insulin and CCK in the acinar pancreas: relationship to hormone action.

I. Goldfine, J. Williams, J. Williams, 1983, International review of cytology.

Insulin receptors in isolated mouse pancreatic acini.

M. Korc, I. Goldfine, H. Sankaran, 1978, Biochemical and biophysical research communications.

Enhancement by glucocorticoid deficiency of the increase in cycloleucine accumulation induced in rat thymocytes by triiodothyronine

I. Goldfine, J. Gray, S. Ingbar, 1979, Journal of endocrinological investigation.

Alterations of Brain Cholecystokinin Receptors in Mice Made Obese with Goldthioglucose

I. Goldfine, John A. Williams, A. Saito, 1982, Journal of neurochemistry.

Preparation of biologically active radioiodinated cholecystokinin for radioreceptor assay and radioimmunoassay.

I. Goldfine, C. Deveney, H. Sankaran, 1979, The Journal of biological chemistry.

The somatostatin receptor on isolated pancreatic acinar cell plasma membranes. Identification of subunit structure and direct regulation by cholecystokinin.

C. Sakamoto, I. Goldfine, J. Williams, 1984, The Journal of biological chemistry.

Insulin action in pancreatic acini from streptozotocin-treated rats. II. Binding of 125I-insulin to receptors.

M. Korc, Y. Iwamoto, I. Goldfine, 1981, The American journal of physiology.

Insulin receptor antiserum and plant lectins mimic the direct effects of insulin on nuclear envelope phosphorylation.

D. B. Burnham, F. Purrello, I. Goldfine, 1983, Science.

Insulin stimulation of nucleoside triphosphatase activity in isolated nuclear envelopes.

R. Vigneri, F. Purrello, I. Goldfine, 1982, Science.

Rapid inibition of basal and glucose-stimulated insulin release by xylazine.

A. Arieff, I. Goldfine, A. Arieff, 1979, Endocrinology.

Acromegaly with normal growth-hormone levels and pituitary histology. Case report.

P. Weinstein, K. Feingold, I. Goldfine, 1979, Journal of Neurosurgery.

Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone.

C. Kahn, D. Neville, I. Goldfine, 1978, Endocrinology.

Radioimmunoassay for human insulin-like growth factor-I receptor: applicability to breast carcinoma specimens and cell lines.

R. Vigneri, O. Ezaki, G. Milazzo, 1991, Metabolism: clinical and experimental.

Interactions of a monoclonal antibody to the insulin receptor with receptors for insulin-like growth factors.

D. Styne, R. Roth, I. Goldfine, 1983, Endocrinology.

Proglumide (gastrin and cholecystokinin receptor antagonist) inhibits insulin secretion in vitro

I. Goldfine, John A. Williams, E. Verspohl, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Characterization of cholecystokinin receptors on bovine gallbladder membranes.

I. Goldfine, R. Steigerwalt, J. Williams, 1984, The American journal of physiology.

Insulin secretion and action and diabetes mellitus

P. Pilch, I. Goldfine, 1992, Journal of cellular biochemistry.

A New Road for Treating the Vascular Complications of Diabetes: So Let's Step on the Gas

Joseph L Evans, I. Goldfine, 2016, Diabetes.

Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid.

Joseph L Evans, I. Goldfine, L. Gavin, 2002, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Insulin and glucagon receptors in Morris hepatomas of varying growth rates.

R. Vigneri, I. Goldfine, V. Pezzino, 1979, Cancer research.

Alterations in brain cholecystokinin receptors after fasting

I. Goldfine, J. Williams, A. Saito, 1981, Nature.

GENETIC ORIGIN OF DIABETES: RE-EVALUATION OF TWIN DATA

I. Goldfine, M. Siperstein, M. Rosenthal, 1976, The Lancet.

Cholecystokinin receptors in the brain: characterization and distribution.

I. Goldfine, H. Sankaran, A. Saito, 1980, Science.

Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction.

I. Goldfine, R. Liddle, R. Taplitz, 1985, The Journal of clinical investigation.

Brain CCK receptors are structurally distinct from pancreas CCK receptors.

C. Sakamoto, I. Goldfine, J. Williams, 1984, Biochemical and biophysical research communications.

Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators.

Joseph L Evans, J. Keck, R. Lum, 2008, Journal of medicinal chemistry.

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF‐1 receptor tyrosine kinases, blocks the growth of HER2‐overexpressing human breast cancer cells

P. Kushner, L. Hodges, J. Youngren, 2008, Journal of cellular biochemistry.

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth

S. Schow, J. Youngren, I. Goldfine, 2006, Molecular Cancer Therapeutics.

Nordihydroguaiaretic Acid (NDGA) Inhibits the IGF-1 and c-erbB2/HER2/neu Receptors and Suppresses Growth in Breast Cancer Cells

J. Youngren, I. Goldfine, B. Maddux, 2005, Breast Cancer Research and Treatment.

Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes

Joseph L Evans, I. Goldfine, C. Albarracin, 2008, Diabetes/metabolism research and reviews.

Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells

I. Goldfine, C. Logsdon, John A. Williams, 1985, The Journal of cell biology.

Insulin action in pancreatic acini from streptozotocin-treated rats. I. Stimulation of protein synthesis.

M. Korc, Y. Iwamoto, I. Goldfine, 1981, The American journal of physiology.

Binding of insulin to isolated nuclei.

G. Smith, I. Goldfine, G. Smith, 1976, Proceedings of the National Academy of Sciences of the United States of America.

The molecular basis for oxidative stress-induced insulin resistance.

Joseph L Evans, I. Goldfine, B. Maddux, 2005, Antioxidants & redox signaling.

Binding of thyroid hormones and their analogues to thyroxine-binding globulin in human serum.

I. Goldfine, S. M. Snyder, R. Cavalieri, 1976, The Journal of biological chemistry.

Properties of the interaction between bovine thyrotropin and bovine thyroid plasma membranes.

I. Goldfine, S. Amir, S. Ingbar, 1976, The Journal of biological chemistry.

Preparation of biologically active 125I-TSH.

I. Goldfine, S. Amir, S. Ingbar, 1974, Endocrinology.

Solubilization and characterization of CCK receptors from mouse pancreas

I. Goldfine, J. Szecowka, J. Williams, 1985, Regulatory Peptides.

Pancreatic CCK receptors: characterization of covalently labeled subunits.

C. Sakamoto, I. Goldfine, J. Williams, 1984, Biochemical and biophysical research communications.

Uptake of L-triiodothyronine into human cultured lymphocytes.

I. Goldfine, A. Holm, E. C. Jorgensen, 1980, Acta endocrinologica.

Transcriptional regulation of human insulin receptor gene by the high‐mobility group protein HMGI(Y)

A. Brunetti, D. Foti, E. Chiefari, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Insulin action in isolated rat thymocytes. II. Independence of insulin and cyclic adenosine monophosphate.

I. Goldfine, P. Sherline, 1972, The Journal of biological chemistry.

Elevated insulin receptor content in human breast cancer.

R. Brand, G. Vannelli, A. Costantino, 1990, The Journal of clinical investigation.

Insulin, insulin receptors, and cancer

R. Vigneri, I. Goldfine, L. Frittitta, 2016, Journal of Endocrinological Investigation.

Insulin receptor signaling

C. Sung, I. Goldfine, 1997 .

Functional variants of the HMGA1 gene and type 2 diabetes mellitus.

T. Mazza, A. Fusco, M. Malloy, 2011, JAMA.

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

Joseph L Evans, F. Buonaguro, I. Goldfine, 2018, Redox biology.

Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity

S. Watson, I. Goldfine, B. Maddux, 2014, PloS one.

Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody

I. Goldfine, S. Adams, Daniel H Bedinger, 2015, The Journal of Pharmacology and Experimental Therapeutics.

High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells.

R. Vigneri, C. Yip, G. Milazzo, 1992, The Journal of clinical investigation.

IGF-I and Insulin Receptor Families in Cancer

A. Belfiore, R. Malaguarnera, I. Goldfine, 2011 .

The nuclear envelope. The major site of insulin binding in rat liver nuclei.

R. Vigneri, G. Smith, I. Goldfine, 1978, The Journal of biological chemistry.

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

G. Reaven, A. Grupe, J. Youngren, 1995, Nature.

The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities.

D. Accili, G. Reaven, R. Vigneri, 2008, Endocrine reviews.

Stimulation of the glucose transport system in isolated mouse pancreatic acini by cholecystokinin and analogues.

M. Korc, I. Goldfine, J. Williams, 1979, The Journal of biological chemistry.

Sulfonylureas: Effects in Vivo and in Vitro

S. Wolfe, I. Goldfine, L. Grauer, 1971 .

Localization of Saturable CCK Binding Sites in Rat Pancreatic Islets by Light and Electron Microscope Autoradiography

C. Sakamoto, I. Goldfine, E. Roach, 1985, Diabetes.

Diabetes in the rat is associated with a reversible postreceptor defect in cholecystokinin action

I. Goldfine, John A. Williams, M. Otsuki, 1984 .

Characterization of cholecystokinin receptor subunits on pancreatic plasma membranes.

C. Sakamoto, I. Goldfine, J. Williams, 1983, Journal of Biological Chemistry.

α-Lipoic Acid: A Multifunctional Antioxidant That Improves Insulin Sensitivity in Patients with Type 2 Diabetes

Joseph L Evans, I. Goldfine, 2000 .

Quantitative electron microscope autoradiographs of 125I-cholecystokinin in pancreatic acini.

I. Goldfine, E. Roach, H. Sankaran, 1982, The American journal of physiology.

Purification of the pancreatic cholecystokinin receptor

I. Goldfine, J. Szecowka, G. Halldén, 1989, Regulatory Peptides.

Brain Cholecystokinin Receptors

C. Sakamoto, I. Goldfine, John A. Williams, 1985 .

Regulation of pancreatic acinar cell insulin receptors by insulin.

I. Goldfine, C. Logsdon, J. Mössner, 1984, The American journal of physiology.

Novel Approach to Treat Insulin Resistance, Type 2 Diabetes, and the Metabolic Syndrome: Simultaneous Activation of PPARα, PPARγ, and PPARδ

Joseph L Evans, Jack J. Lin, I. Goldfine, 2005 .

Effective treatments for insulin resistance: trim the fat and douse the fire

Joseph L Evans, J. Youngren, I. Goldfine, 2004, Trends in Endocrinology & Metabolism.

A. Brunetti, U. Kintscher, B. Arcidiacono, 2020, EBioMedicine.

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

K. Clément, C. Dina, P. Boutin, 2005, Nature Genetics.

Insulin Action in Isolated Rat Thymocytes

I. Goldfine, P. Sherline, 1972 .

Insulin-like growth factor-I receptors are overexpressed and predict a low risk in human breast cancer.

G M Clark, W. McGuire, G. Clark, 1993, Cancer research.

Sporadic amplification of the insulin receptor gene in human breast cancer

F. Waldman, R. Vigneri, V. Papa, 1997, Journal of endocrinological investigation.

Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia.

D. Accili, O. McGuinness, J. Youngren, 2006, American journal of physiology. Endocrinology and metabolism.

A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components

U. Hodoğlugil, F. Baudi, C. Pullinger, 2013, Scientific Reports.

Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

J. Youngren, I. Goldfine, F. Schaufele, 2014, PloS one.

Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid.

J. Lawrence, I. Goldfine, B. Maddux, 2001, Diabetes.

Selective Allosteric Antibodies to the Insulin Receptor for the Treatment of Hyperglycemic and Hypoglycemic Disorders

I. Goldfine, Daniel H Bedinger, P. Scannon, 2014, Journal of diabetes science and technology.

Comment on: Marquez et al. Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk. Diabetes 2012;61:524–530

C. Pullinger, A. Brunetti, D. Foti, 2012, Diabetes.

Aging and Insulin Resistance: Just Say iNOS

Joseph L Evans, I. Goldfine, 2013, Diabetes.

Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action.

G. Smith, I. Goldfine, A. Jones, 1977, Proceedings of the National Academy of Sciences of the United States of America.

The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract

Michael S. German, David C. Olson, D. Olson, 1997, Nature Biotechnology.

Entry of insulin into human cultured lymphocytes: electron microscope autoradiographic analysis.

I. Goldfine, A. Jones, G. Hradek, 1978, Science.

A rapid and simple one step method for isolation of poly(A)+ RNA from cells in monolayer.

E. Brown, V. Papa, I. Goldfine, 1990, Endocrinology.

Binding of thyroid hormones and analogues to the human plasma protein prealbumin.

T. A. Andrea, I. Goldfine, R. Cavalieri, 1980, Biochemistry.

Regulation of the insulin receptor by a monoclonal anti-receptor antibody. Evidence that receptor down regulation can be independent of insulin action.

R. Roth, I. Goldfine, B. Maddux, 1983, The Journal of biological chemistry.

Regulation of hepatic glycogen synthesis during fetal development: roles of hydrocortisone, insulin, and insulin receptors.

W. Glinsmann, I. Goldfine, H. Eisen, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.

U. Hodoğlugil, M. Malloy, C. Pullinger, 2009, Metabolic syndrome and related disorders.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Autoradiographic analysis of 125I-insulin-like growth factor II internalization into pancreatic acini.

I. Goldfine, E. Roach, J. Mossner, 1986, Diabetes research and clinical practice.

Methylamine and monensin do not block insulin internalization but do influence the intracellular distribution and action of insulin in pancreatic acini from diabetic mice.

I. Goldfine, N. Potau, E. Roach, 1984, Endocrinology.

Chloroquine stimulation of insulin binding to IM-9 lymphocytes: evidence for action at a nonlysosomal site.

Y. Iwamoto, I. Goldfine, B. Maddux, 1981, Biochemical and biophysical research communications.

Reduced postprandial cholecystokinin (CCK) secretion in patients with noninsulin-dependent diabetes mellitus: evidence for a role for CCK in regulating postprandial hyperglycemia.

R. Brand, I. Goldfine, R. Liddle, 1993, The Journal of clinical endocrinology and metabolism.

Membrane glycoprotein PC-1 and insulin resistance

G. Dohm, J. Youngren, I. Goldfine, 1998, Molecular and Cellular Biochemistry.

Monoclonal antibodies to the human insulin receptor mimic a spectrum of biological effects in transfected 3T3/HIR fibroblasts without activating receptor kinase.

A. Brunetti, C. Sung, I. Goldfine, 1989, Biochemical and biophysical research communications.

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance.

G Scarlato, L. Iacoviello, A. Pizzuti, 1999, Diabetes.

Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T.

Xiaojuan Li, S. Majumdar, M. Schambelan, 2008, Magnetic resonance imaging.

A pilot dose‐escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer

E. Small, J. Rosenberg, I. Goldfine, 2008, BJU international.

Effect of intracellular Ca2+ on insulin-like growth factor II. internalization into pancreatic acini. Roles of insulin and cholecystokinin.

I. Goldfine, C. Logsdon, N. Potau, 1984, The Journal of biological chemistry.

Insulin-ricin B chain conjugate has enhanced biological activity in insulin-insensitive cells.

Y. Iwamoto, R. Roth, I. Goldfine, 1983, Endocrinology.

In vivo regulation of cell surface and intracellular insulin binding sites by insulin.

R. Vigneri, I. Goldfine, V. Pezzino, 1978, The Journal of biological chemistry.

Consumption coagulopathy in miliary tuberculosis.

H. Kingdon, I. Goldfine, W. Barclay, 1969, Annals of internal medicine.

Contributions of the American Journal of Physiology to the discovery of insulin.

J. Youngren, I. Goldfine, 1998, The American journal of physiology.

Degradation of Insulin by Isolated Mouse Pancreatic Acini: Evidence for Cell Surface Protease Activity

Y. Iwamoto, R. Roth, I. Goldfine, 1984, Diabetes.

Insulin receptor autophosphorylation in cultured myoblasts correlates to glucose disposal in Pima Indians.

R. Pratley, J. Youngren, I. Goldfine, 1999, American journal of physiology. Endocrinology and metabolism.

ATP and other nucleoside triphosphates inhibit the binding of insulin to its receptor.

R. Vigneri, R. Roth, I. Goldfine, 1984, Metabolism: clinical and experimental.

Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.

R. Terkeltaub, D. Accili, Kristen Johnson, 2005, Diabetes.

PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity

R. Vigneri, J. Youngren, I. Goldfine, 1996, Diabetologia.

The biological and clinical roles of increased insulin receptors in human breast cancer.

R. Vigneri, I. Goldfine, 1992, Cancer treatment and research.

Parallel synthesis of diarylureas and their evaluation as inhibitors of insulin-like growth factor receptor.

R. Guy, J. Youngren, I. Goldfine, 2006, Journal of combinatorial chemistry.

A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1−/− mouse model of KATP hyperinsulinism

Kirk W. Johnson, I. Goldfine, Puja Patel, 2018, mAbs.

Cholecystokinin and insulin regulate insulin-like growth factor II binding to pancreatic receptors; evidence of a role for intracellular calcium.

I. Goldfine, N. Potau, J. Mössner, 1984, Biochemical and biophysical research communications.

Insulinlike growth factors bind to specific receptors in isolated pancreatic acini.

I. Goldfine, A. Bailey, R. Humbel, 1984, American Journal of Physiology.

Receptors for cholecystokinin and insulin in isolated pancreatic acini: hormonal control of secretion and metabolism.

M. Korc, I. Goldfine, H. Sankaran, 1981, Federation proceedings.

Insulin receptor expression and clinical outcome in node-negative breast cancer.

M. Mathieu, D. Allred, G. Clark, 1997, Proceedings of the Association of American Physicians.

Endocytosis, recycling, and degradation of the insulin receptor. Studies with monoclonal antireceptor antibodies that do not activate receptor kinase.

R. Vigneri, A. Brunetti, I. Goldfine, 1989, The Journal of biological chemistry.

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle

Xiaojuan Li, M. Schambelan, U. Masharani, 2011, PloS one.

Effects of Controlled-Release Alpha Lipoic Acid in Lean, Nondiabetic Patients with Polycystic Ovary Syndrome

Joseph L Evans, U. Masharani, J. Youngren, 2010, Journal of diabetes science and technology.

Hyperleydigism: a cause of severe pubertal gynecomastia.

I. Goldfine, R. Rosenfield, R. Landau, 1971, The Journal of clinical endocrinology and metabolism.

Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice

I. Goldfine, S. Adams, Daniel H Bedinger, 2015, Journal of cellular biochemistry.

Inadvertent sulfonylurea overdosage and hypoglycemia in an elderly woman: failure of serum hypoglycemia screening.

I. Goldfine, R. Rushakoff, K. Earle, 2003, Diabetes technology & therapeutics.

Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer.

E. Small, I. Goldfine, D. Nonaka, 2007, Urologic oncology.

Role of PC‐1 in The Etiology of Insulin Resistance

J. Youngren, I. Goldfine, B. Maddux, 1999, Annals of the New York Academy of Sciences.

Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population.

M. Malloy, C. Pullinger, J. Kane, 2014, Metabolic syndrome and related disorders.

Insulin Regulation of Sugar Transport in Isolated Pancreatic Acini from Diabetic Mice

I. Goldfine, John A. Williams, Ira D Goldfine, 1982, Diabetes.

Evidence that calcium is a hormonal second messenger

M. Korc, I. Goldfine, John A. Williams, 1978 .

Intracellular binding sites for insulin are immunologically distinct from those on the plasma membrane

C. Kahn, R. Vigneri, I. Goldfine, 1977, Nature.

Cerebral Salt‐Wasting Syndrome: Diagnosis by Urine Sodium Excretion

A. Arieff, I. Goldfine, R. Gabbai, 2017, The American journal of the medical sciences.

Negative and positive site-site interactions, and their modulation by pH, insulin analogs, and monoclonal antibodies, are preserved in the purified insulin receptor.

I. Goldfine, P. De Meyts, H. Gattner, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Diabetes in the rat is associated with a reversible postreceptor defect in cholecystokinin action.

I. Goldfine, M. Otsuki, J. Williams, 1984, Gastroenterology.

Insulin Activity: The Solid Matrix

J. Roth, G. Marinetti, I. Goldfine, 1973, Science.

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

K. Jarnagin, W. Rutter, Y. Kan, 1985, Cell.

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

G. Hortobagyi, E. Gehan, D. Greenblatt, 1979, Cancer research.

Mechanism of glucocorticoid receptor down-regulation by glucocorticoids.

S. Rosewicz, I. Goldfine, I. Goldfine, 1988, The Journal of biological chemistry.

Original article Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer

E. Small, I. Goldfine, D. Nonaka, 2007 .

XOMA 052, an anti‐IL‐1β monoclonal antibody, prevents IL‐1β‐mediated insulin resistance in 3T3‐L1 adipocytes

A. Mirza, I. Goldfine, B. Maddux, 2013, Obesity.

Novel approach to treat insulin resistance, type 2 diabetes, and the metabolic syndrome: simultaneous activation of PPARalpha, PPARgamma, and PPARdelta.

Joseph L Evans, Jack J. Lin, I. Goldfine, 2005, Current diabetes reviews.

Identification and initial characterization of insulin receptor-like immunoreactivity in human plasma.

A. Costantino, R. Vigneri, V. Papa, 1992, The Journal of clinical endocrinology and metabolism.

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

S. Watson, I. Goldfine, B. Maddux, 2012, Diabetes.

Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α‐lipoic acid

Joseph L Evans, R. Vigneri, I. Goldfine, 2014, Clinical endocrinology.

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody

S. Watson, I. Goldfine, B. Maddux, 2013, mAbs.

The effect of phenformin and other adenosine triphosphate (ATP)‐lowering agents on insulin binding to IM‐9 human cultured lymphocytes

R. Vigneri, I. Goldfine, B. Maddux, 1984, Journal of cellular biochemistry.

Unraveling the riddle of insulin resistance.

I. Goldfine, 1999, The Journal of laboratory and clinical medicine.

Influence of gender on the relationship between insulin sensitivity, adiposity, and plasma lipids in lean nondiabetic subjects.

U. Masharani, J. Youngren, I. Goldfine, 2009, Metabolism: clinical and experimental.

S-4: Insulin receptor inhibitors as a cause of insulin resistance

G. Dohm, J. Youngren, I. Goldfine, 2009 .

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

G. Dohm, J. Youngren, I. Goldfine, 1996, Diabetes.

Structure-based de novo design of ligands using a three-dimensional model of the insulin receptor.

L. Kotra, Lianhu Wei, I. Goldfine, 2004, Bioorganic & medicinal chemistry letters.

Insulin action in pancreatic acini from streptozotocin-treated rats. III. Electron microscope autoradiography of 125I-insulin.

I. Goldfine, A. Jones, G. Hradek, 1981, The American journal of physiology.

Letter: Insulin activity: the solid matrix.

C. Kahn, R. Lefkowitz, J. Roth, 1973, Science.

Insulin binding sites on the nuclear envelope: potential relationship to mRNA metabolism

R. Vigneri, F. Purrello, I. Goldfine, 1982, Journal of cellular biochemistry.

Alterations of brain cerebral cortex CCK receptors in the ob/ob mouse.

I. Goldfine, A. Saito, J. Williams, 1981, Endocrinology.

Role of myogenin in myoblast differentiation and its regulation by fibroblast growth factor.

A Brunetti, A. Brunetti, I. Goldfine, 1990, The Journal of biological chemistry.

Oral gene therapy: a novel method for the manufacture and delivery of protein drugs.

I. Goldfine, S. Rothman, H. Tseng, 2005, Diabetes technology & therapeutics.

Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells.

J. Youngren, I. Goldfine, B. Maddux, 2001, Diabetes.

α-Lipoic Acid: A Multifunctional Antioxidant That Improves Insulin Sensitivity in Patients with Type 2 Diabetes

Joseph L Evans, I. Goldfine, 2000 .

A RAPID AND SIMPLE ONE STEP METHOD FOR ISOLATION OF POLY(A)

E. Brown, V. Papa, I. Goldfine, 1990 .