I. Rogatsky

发表

Regulation of Glucocorticoid and Estrogen Receptor Activity by Phosphorylation

M. Garabedian, I. Rogatsky, A. Hittelman, 1998 .

Transcription cofactor GRIP1 differentially affects myeloid cell–driven neuroinflammation and response to IFN-β therapy

I. Rogatsky, Sanda Mimouna, David A. Rollins, 2020, The Journal of experimental medicine.

Dual Cross-Linking Chromatin Immunoprecipitation Protocol for Next-Generation Sequencing (ChIPseq) in Macrophages.

I. Rogatsky, David A. Rollins, Inez Rogatsky, 2019, Methods in molecular biology.

Phosphorylation and Inhibition of Rat Glucocorticoid Receptor Transcriptional Activation by Glycogen Synthase Kinase-3 (GSK-3)

M. Garabedian, I. Rogatsky, Carine L. M. Waase, 1998, The Journal of Biological Chemistry.

Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages

Rong Li, Xiaoyu Hu, I. Rogatsky, 2018, eLife.

Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling

S. Nechaev, K. Adelman, I. Rogatsky, 2009, Proceedings of the National Academy of Sciences.

Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex.

M. Garabedian, I. Rogatsky, J. Trowbridge, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.

K. Yamamoto, I. Rogatsky, R. Christy, 2004, Molecular biology of the cell.

Glucocorticoid receptor phosphorylation differentially affects target gene expression.

Claudio N. Cavasotto, C. Cavasotto, S. Logan, 2008, Molecular endocrinology.

Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages

M. Pufall, Xiaoyu Hu, I. Rogatsky, 2017, Nature Communications.

Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase‐3 response element that mediates regulation by phorbol esters and hormones

K. Yamamoto, I. Rogatsky, K. Zarember, 2001, The EMBO journal.

Distinct Glucocorticoid Receptor Transcriptional Regulatory Surfaces Mediate the Cytotoxic and Cytostatic Effects of Glucocorticoids

M. Garabedian, D. Pearce, I. Rogatsky, 1999, Molecular and Cellular Biology.

Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase.

S. Logan, M. Garabedian, I. Rogatsky, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells.

R. Panettieri, I. Rogatsky, S. Keslacy, 2010, American journal of respiratory cell and molecular biology.

Drug discovery for inflammatory diseases

I. Rogatsky, 2003, Expert opinion on biological therapy.

Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor

K. Yamamoto, K. Yamamoto, M. Garabedian, 1997, Molecular and cellular biology.

Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.

Robert J. Christy, Keith R. Yamamoto, K. Yamamoto, 2003, Molecular biology of the cell.

Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms.

I. Rogatsky, Jamie R. Flammer, Inez Rogatsky, 2011, Molecular endocrinology.

MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor.

M. Garabedian, I. Rogatsky, Michael J Garabedian, 2006, Molecular endocrinology.

Nuclear receptors in inflammation control: Repression by GR and beyond

I. Rogatsky, Y. Chinenov, Rebecca Gupte, 2013, Molecular and Cellular Endocrinology.

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression

Y. Shang, I. Rogatsky, David A. Rollins, 2020, Nature Communications.

The transcriptional repressor Hes1 attenuates inflammation via regulating transcriptional elongation

M. Gessler, Y. Shang, Xiaoyu Hu, 2016, Nature Immunology.

Preparing the first responders: building the inflammatory transcriptome from the ground up.

K. Adelman, I. Rogatsky, Inez Rogatsky, 2014, Molecular cell.

Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle

K. Adelman, I. Rogatsky, Ginger W. Muse, 2013, Proceedings of the National Academy of Sciences.

Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus.

S. Taneja, S. Ha, S. Logan, 2002, Molecular biology of the cell.

Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

K. Yamamoto, M. Garabedian, B. Darimont, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Cytokines and chemokines recruit and activate specialized effector cells to sites of inflammation1. However, excessive production of inflammatory mediators leads to immune hyper-activation and tissue damage and contributes to the pathogenesis of inflammatory and autoimmune disorders such as rheumato

M. Gessler, Y. Shang, Xiaoyu Hu, 2016 .

Gene-specific mechanisms direct Glucocorticoid Receptor-driven 1 repression of inflammatory response genes in macrophages 2 3 4 5

Rong Li, Xiaoyu Hu, I. Rogatsky, 2022 .

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis

I. Rogatsky, Y. Chinenov, M. Sacta, 2016, Nature Communications.

The Type I Interferon Signaling Pathway Is a Target for Glucocorticoid Inhibition

C. Glass, L. Ivashkiv, I. Rogatsky, 2010, Molecular and Cellular Biology.

Genomic glucocorticoid action in embryonic mouse neural stem cells

A. P. Monaghan-Nichols, U. Chandran, D. DeFranco, 2023, Molecular and Cellular Endocrinology.

Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages

I. Rogatsky, Y. Chinenov, M. Sacta, 2014, BMC Genomics.

Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids

I. Rogatsky, Y. Chinenov, Jamie R. Flammer, 2012, Proceedings of the National Academy of Sciences.

The GRIP1:IRF3 interaction as a target for glucocorticoid receptor‐mediated immunosuppression

Xiaoyu Hu, I. Rogatsky, C. Pantoja, 2006, The EMBO journal.

Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms

M. Garabedian, I. Rogatsky, J. Trowbridge, 1997, Molecular and cellular biology.

Potentiation of Human Estrogen Receptor α Transcriptional Activation through Phosphorylation of Serines 104 and 106 by the Cyclin A-CDK2 Complex*

M. Garabedian, I. Rogatsky, J. Trowbridge, 1999, The Journal of Biological Chemistry.

Glucocorticoid modulation of cytokine signaling.

L. Ivashkiv, I. Rogatsky, Inez Rogatsky, 2006, Tissue antigens.

There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inflammation by the glucocorticoid receptor

I. Rogatsky, David A. Rollins, N. H. Uhlenhaut, 2016, Steroids.

Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism.

I. Rogatsky, David A. Rollins, Maddalena Coppo, 2015, Molecular endocrinology.

Glucocorticoid Signaling: An Update from a Genomic Perspective.

I. Rogatsky, Y. Chinenov, M. Sacta, 2016, Annual review of physiology.

Glucocorticoids and the innate immune system: Crosstalk with the Toll-like receptor signaling network

I. Rogatsky, Y. Chinenov, Inez Rogatsky, 2007, Molecular and Cellular Endocrinology.

Epigenetics and the IRFs: A complex interplay in the control of immunity and autoimmunity

I. Rogatsky, A. Pernis, U. Chandrasekaran, 2014, Autoimmunity.

GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression

I. Rogatsky, Y. Chinenov, M. Sacta, 2008, Proceedings of the National Academy of Sciences.

Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

K. Yamamoto, I. Rogatsky, D. Leitman, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Phosphorylation of Liver X Receptor α Selectively Regulates Target Gene Expression in Macrophages

Claudio N. Cavasotto, E. Fisher, C. Cavasotto, 2008, Molecular and Cellular Biology.

Cyclin Dependent Kinase Regulation of Estrogen Receptor Phosphorylation and Transcriptional Activation

M. Garabedian, I. Rogatsky, J. Trowbridge, 2002 .

Glucocorticoid-Dependent Phosphorylation of the Transcriptional Coregulator GRIP1

I. Rogatsky, Y. Chinenov, J. Dobrovolna, 2011, Molecular and Cellular Biology.

Complex -Catenin β Cyclin D1 by Targeting the Tcf- The Glucocorticoid Receptor Represses

I. Rogatsky, E. Leslie, S. Takayama, 2013 .

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression

Rong Li, Y. Shang, Xiaoyu Hu, 2020, Nature Communications.

The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

C. Blobel, P. Lipsky, I. Rogatsky, 2021, bioRxiv.

The Biologist’s Guide to the Glucocorticoid Receptor’s Structure

I. Rogatsky, K. De Bosscher, F. Peelman, 2023, Cells.

Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages

M. Pufall, Xiaoyu Hu, I. Rogatsky, 2017, Nature Communications.

RNA polymerase II stalling mediates cytokine gene expression

K. Adelman, I. Rogatsky, 2010, Cell cycle.

Selective Activation of the Glucocorticoid Receptor by Steroid Antagonists in Human Breast Cancer and Osteosarcoma Cells*

M. Garabedian, I. Rogatsky, H. Kinyamu, 2000, The Journal of Biological Chemistry.

The Glucocorticoid Receptor Represses Cyclin D1 by Targeting the Tcf-β-Catenin Complex*

B. Darimont, I. Rogatsky, L. Schwarcz, 2006, Journal of Biological Chemistry.