N. Georgopapadakou

发表

Mammalian microsomal and soluble Ras‐processing peptidase activities are distinct

A. Hitz, N. Georgopapadakou, Nafsika H. Georgopapadakou, 1996, FEBS letters.

β-Lactamase inhibitors: evolving compounds for evolving resistance targets

N. Georgopapadakou, 2004 .

Outer membrane penetration by (2,3)-methylenepenams

N. Georgopapadakou, J. Chapman, 1987, Antimicrobial Agents and Chemotherapy.

Monocyclic β-lactam antibiotics produced by bacteria

J. S. Wells, D. Floyd, K. Bush, 1981, Nature.

Penicillin-Bindi ng Proteins andBacterial Resistance to,3-Lactams

N. Georgopapadakou, 1993 .

Chemical modifications of the active site of Streptomyces R61 DD-carboxypeptidase.

R. Neubeck, N. Georgopapadakou, M. Ondetti, 2005, European journal of biochemistry.

Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria

K. Bush, R. Sykes, N. Georgopapadakou, 1982, Antimicrobial Agents and Chemotherapy.

Anticancer therapeutics: a surge of new developments increasingly target tumor and stroma.

N. Georgopapadakou, H. Broxterman, 2007, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Antibiotic Resistance in Biofilms

N. Georgopapadakou, 2005 .

Porins and lipopolysaccharide of Escherichia coli ATCC 25922 and isogenic rough mutants.

N. Georgopapadakou, A. Bertasso, C. McCaffrey, 1993, FEMS microbiology letters.

Streptomyces R61 DD-carboxypeptidase: hydrolysis of X-D-alanyl-D-alanine peptides measured by a fluorometric assay.

R. Neubeck, E. Gordon, N. Georgopapadakou, 1984, Analytical biochemistry.

A modified radiometric assay for 3-hydroxy-3-methylglutaryl coenzyme a reductase

N. Georgopapadakou, B. A. Dix, 1984, Lipids.

Strategies in β-lactam Design

N. Georgopapadakou, F. Neuhaus, F. C. Neuhaus, 1992 .

Comparison of the Tu elongation factors from Staphylococcus aureus and Escherichia coli: possible basis for elfamycin insensitivity

N. Georgopapadakou, J. Watkins, C. Hall, 1991, Antimicrobial Agents and Chemotherapy.

A continuous fluorometric assay of myristoyl-coenzyme A:protein N-myristoyltransferase.

N. Georgopapadakou, D. Pompliano, C. Pennise, 2002, Analytical Biochemistry.

Chapter 13. Bacterial Penicillin-Binding Proteins

N. Georgopapadakou, 1983 .

Possible physiological functions of penicillin-binding proteins in Staphylococcus aureus

N. Georgopapadakou, Y. Mauriz, B. A. Dix, 1986, Antimicrobial Agents and Chemotherapy.

Binding of monobactams to penicillin-binding proteins of Escherichia coli and Staphylococcus aureus: relation to antibacterial activity

R. Sykes, N. Georgopapadakou, S. Smith, 1983, Antimicrobial Agents and Chemotherapy.

Penicillin-binding proteins in a Staphylococcus aureus strain resistant to specific beta-lactam antibiotics

N. Georgopapadakou, S. Smith, D. Bonner, 1982, Antimicrobial Agents and Chemotherapy.

SQ 26,180, a novel monobactam. I Taxonomy, fermentation and biological properties.

J. S. Wells, K. Bush, R. Sykes, 1982, The Journal of antibiotics.

Binding of beta-lactam antibiotics to penicillin-binding proteins of Staphylococcus aureus and Streptococcus faecalis: relation to antibacterial activity

N. Georgopapadakou, F. Y. Liu, 1980, Antimicrobial Agents and Chemotherapy.

Penicillin-binding proteins in bacteria

N. Georgopapadakou, F. Y. Liu, 1980, Antimicrobial Agents and Chemotherapy.

Binding of83-Lactam Antibiotics toPenicillin-Bindi ng Proteins ofStaphylococcus aureus andStreptococcus faecalis: Relation

N. Georgopapadakou, 1980 .

Penicillin-binding proteins in Bacteroides fragilis.

R. Sykes, N. Georgopapadakou, S. Smith, 1983, The Journal of antibiotics.

resistance to beta-lactams. Penicillin-binding proteins and bacterial

N. Georgopapadakou, 2013 .

Isolation of the penicillin-binding peptide from D-alanine carboxypeptidase of Bacillus subtilis.

J. Strominger, N. Georgopapadakou, S. Hammarström, 1977, Proceedings of the National Academy of Sciences of the United States of America.

The wobbly status of ketolides: where do we stand?

N. Georgopapadakou, 2014, Expert opinion on investigational drugs.

Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by β-Lactamases

N. Georgopapadakou, M. Sergeeva, V. Doppalapudi, 2004, Antimicrobial Agents and Chemotherapy.

Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by (cid:2) -Lactamases

N. Georgopapadakou, M. Sergeeva, V. Doppalapudi, 2004 .

Inhibition of Inositol Phosphorylceramide Synthase by Aureobasidin A in Candida and AspergillusSpecies

Wenyan Zhong, N. Georgopapadakou, M. Jeffries, 2000, Antimicrobial Agents and Chemotherapy.

Inhibition of yeast inositol phosphorylceramide synthase by aureobasidin A measured by a fluorometric assay

Wenyan Zhong, N. Georgopapadakou, D. J. Murphy, 1999, FEBS letters.

Does cephalothin inhibit matrix metalloproteinases?

N. Georgopapadakou, 1996, Antimicrobial agents and chemotherapy.

Fluorometric assay for fleroxacin uptake by bacterial cells

N. Georgopapadakou, J. Chapman, 1989, Antimicrobial Agents and Chemotherapy.

Routes of quinolone permeation in Escherichia coli

N. Georgopapadakou, J. Chapman, 1988, Antimicrobial Agents and Chemotherapy.

Fleroxacin resistance in Escherichia coli

N. Georgopapadakou, A. Bertasso, J. Chapman, 1989, Antimicrobial Agents and Chemotherapy.

Effects of squalene epoxidase inhibitors on Candida albicans

N. Georgopapadakou, A. Bertasso, 1992, Antimicrobial Agents and Chemotherapy.

Synthesis of inhibitors of 2,3-oxidosqualene-lanosterol cyclase. 2. Cyclocondensation of .gamma.,.delta.-unsaturated-.beta.-keto esters with imines

N. Georgopapadakou, A. Polak, P. Hartman, 1992 .

Cancer research 2001: drug resistance, new targets and drug combinations.

N. Georgopapadakou, H. Broxterman, 2001, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Chitin synthase in Candida albicans: comparison of digitonin-permeabilized cells and spheroplast membranes

N. Georgopapadakou, S. Smith, 1985, Journal of bacteriology.

Dual-action penems and carbapenems.

P. Rossman, N. Georgopapadakou, D. Pruess, 1992, Journal of medicinal chemistry.

Bacterial Enzymes Interacting with β-Lactam Antibiotics

R. Sykes, N. Georgopapadakou, 1983 .

Emerging Targets in Antibacterial and Antifungal Chemotherapy

N. Georgopapadakou, J. Sutcliffe, 2012, Springer US.

Anticancer therapeutics: "Addictive" targets, multi-targeted drugs, new drug combinations.

N. Georgopapadakou, H. Broxterman, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Probing the binding site of the penicillin side-chain based on the tipper-Strominger hypothesis

N. Georgopapadakou, S. Hanessian, Claude Couture, 1993 .

Mechanisms of action of cephalosporin 3'-quinolone esters, carbamates, and tertiary amines in Escherichia coli

N. Georgopapadakou, A. Bertasso, 1993, Antimicrobial Agents and Chemotherapy.

Mechanisms ofAction ofCephalosporin 3'-Quinolone Esters, Carbamates, andTertiary AminesinEscherichia coli

N. Georgopapadakou, A. Bertasso, 1993 .

Dual-action cephalosporins incorporating a 3'-tertiary-amine-linked quinolone.

F. Konzelmann, N. Georgopapadakou, D. Pruess, 1994, Journal of medicinal chemistry.

Infectious disease 2001: drug resistance, new drugs.

N. Georgopapadakou, 2002, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Effects of Drugs on Lipids and Membrane Integrity of Fungi

N. Georgopapadakou, 1989 .

Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans

N. Georgopapadakou, S. Smith, P. Funke, 1987, Antimicrobial Agents and Chemotherapy.

Effects ofSqualene Epoxidase Inhibitors onCandida albicans

N. Georgopapadakou, A. Bertasso, 1992 .

Monobactams—monocyclic β -lactam antibiotics produced by bacteria

J. S. Wells, K. Bush, R. Sykes, 1981 .

Update on antifungals targeted to the cell wall: focus on β-1,3-glucan synthase inhibitors

N. Georgopapadakou, N H Georgopapadakou, 2001, Expert opinion on investigational drugs.

Monobactams--monocyclic beta-lactam antibiotics produced by bacteria.

J. S. Wells, K. Bush, R. Sykes, 1981, The Journal of antimicrobial chemotherapy.

Infectious disease 2000: drug resistance and new drugs.

N. Georgopapadakou, 2000, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Antibiotic Resistance In Enterobacteria

N. Georgopapadakou, 2001 .

Quinolone accumulation in Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus

N. Georgopapadakou, A. Bertasso, C. McCaffrey, 1992, Antimicrobial Agents and Chemotherapy.

Effects of elfamycins on elongation factor Tu from Escherichia coli and Staphylococcus aureus

N. Georgopapadakou, J. Watkins, C. Hall, 1989, Antimicrobial Agents and Chemotherapy.

Discontinued drugs in 2005: anti-infectives

N. Georgopapadakou, 2007, Expert opinion on investigational drugs.

Dual-action cephalosporins: cephalosporin 3'-quinolone carbamates.

P. Rossman, F. Konzelmann, N. Georgopapadakou, 1991, Journal of medicinal chemistry.

New cancer therapeutics: target-specific in, cytotoxics out?

N. Georgopapadakou, H. Broxterman, 2004, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

EM5400, a family of monobactam antibiotics produced by Agrobacterium radiobacter. I. Taxonomy, fermentation and biological properties.

J. S. Wells, K. Bush, R. Sykes, 1982, The Journal of antibiotics.

Monocyclic beta-lactam antibiotics produced by bacteria.

J. S. Wells, D. Floyd, K. Bush, 1981, Nature.

Letter: Concerning the intermediacy of uro'gen III and of a heptacarboxylic uro'gen in corrinoid biosynthesis.

I. Scott, C. Townsend, N. Georgopapadakou, 1975, Journal of the American Chemical Society.

N,N-Dichloroaminosulfonic acids as novel topical antimicrobial agents.

S. Nair, N. Georgopapadakou, R. Jain, 2009, Bioorganic & medicinal chemistry letters.

EM5519, a new broad-spectrum antibiotic produced by Pseudomonas fluorescens.

R. Sykes, N. Georgopapadakou, E. Meyers, 1983, The Journal of antibiotics.

Mode of action of the dual-action cephalosporin Ro 23-9424

N. Georgopapadakou, R. Cleeland, K. Chan, 1989, Antimicrobial Agents and Chemotherapy.

Low-level resistance to the cephalosporin 3'-quinolone ester Ro 23-9424 in Escherichia coli

N. Georgopapadakou, A. Bertasso, J. Chapman, 1995, Antimicrobial agents and chemotherapy.

Effects of quinolones on nucleoid segregation in Escherichia coli

N. Georgopapadakou, A. Bertasso, N H Georgopapadakou, 1991, Antimicrobial Agents and Chemotherapy.

Escherichia coli resistant to cephalosporins and quinolones is still susceptible to the cephalosporin-quinolone ester Ro 23-9424

N. Georgopapadakou, A. Bertasso, J. Pace, 1991, Antimicrobial Agents and Chemotherapy.

Monocyclic and tricyclic analogs of quinolones: mechanism of action

N. Georgopapadakou, A. Wick, B. A. Dix, 1987, Antimicrobial Agents and Chemotherapy.

Mode of action of azthreonam

R. Sykes, N. Georgopapadakou, S. Smith, 1982, Antimicrobial Agents and Chemotherapy.

Antifungals targeted to protein modification: focus on protein N-myristoyltransferase

N. Georgopapadakou, 2002, Expert opinion on investigational drugs.

Synthesis of Sulfur- and Sulfoxide-Substituted 2,3-Oxidosqualenes and Their Evaluation as Inhibitors of 2,3-Oxidosqualene-Lanosterol Cyclase

N. Georgopapadakou, Y. Zheng, P. Hartman, 1995 .

Biosynthesis of polyketides. Purification and inhibition studies of 6-methylsalicylic acid synthase

N. Georgopapadakou, A. Scott, C. Subbarayan, 1974 .

Penicillin-binding proteins and bacterial resistance to beta-lactams

N. Georgopapadakou, N H Georgopapadakou, 1993, Antimicrobial Agents and Chemotherapy.

Screening assays for protein synthesis inhibitors.

N. Georgopapadakou, J. Watkins, A. Bertasso, 1992, The Journal of antibiotics.

Cephalosporin 3'-quinolone esters with a dual mode of action.

N. Georgopapadakou, D. Pruess, R. Cleeland, 1990, Journal of medicinal chemistry.

Cancer research 2000: drug resistance, new targets and drugs in development.

N. Georgopapadakou, H. Broxterman, 2000, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Prospects for new antibacterials: can we do better?

N. Georgopapadakou, 2014, Expert opinion on investigational drugs.

A radiometric assay for Ras-processing peptidase using an enzymatically radiolabeled peptide.

N. Georgopapadakou, J. Watkins, T. Lambros, 1994, Analytical biochemistry.

38th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) San Diego, USA, 24–27 September 1998

N. Georgopapadakou, 1998 .

Routes ofQuinolone Permeation inEscherichia coli

N. Georgopapadakou, J. Chapman, 1988 .

Superbugs & Superdrugs: A Focus on Antibacterials – 6th Annual SMi Conference

N. Georgopapadakou, 2004, Expert opinion on emerging drugs.

Interaction between monobactams and Streptomyces R61 DD-carboxypeptidase.

N. Georgopapadakou, S. Smith, C. Cimarusti, 2005, European journal of biochemistry.

ModeofAction oftheDual-Action Cephalosporin Ro23-9424

N. Georgopapadakou, R. Cleeland, A. Bertasso, 1989 .

Antifungal agents: chemotherapeutic targets and immunologic strategies

T J Walsh, N. Georgopapadakou, T. Walsh, 1996, Antimicrobial agents and chemotherapy.

Human mycoses: drugs and targets for emerging pathogens.

N. Georgopapadakou, T. Walsh, N. Georgopapadakou, 1994, Science.

On B12 biosynthesis and evolution.

N. Georgopapadakou, A. Scott, 1977, Journal of theoretical biology.