Yan Guo

发表

Regulation of Heparin-Binding EGF-Like Growth Factor by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinoma

P. Harari, C. Chung, R. Slebos, 2010, PloS one.

lncRNA expression in the auditory forebrain during postnatal development.

T. Hackett, Yan Guo, Shilin Zhao, 2016, Gene.

Transcriptional maturation of the mouse auditory forebrain

T. Hackett, D. Polley, K. Mirnics, 2015, BMC Genomics.

Large Scale Comparison of Gene Expression Levels by Microarrays and RNAseq Using TCGA Data

Jiang Li, Y. Shyr, D. Samuels, 2013, PloS one.

Multi-perspective quality control of Illumina RNA sequencing data analysis

Olivia I. Koues, Y. Shyr, K. Vickers, 2016, Briefings in functional genomics.

Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data

J. Long, Jiang Li, Bing Zhang, 2012, BMC Genomics.

Evaluation of Allele Frequency Estimation Using Pooled Sequencing Data Simulation

Jiang Li, Y. Shyr, D. Samuels, 2013, TheScientificWorldJournal.

Advanced Datamining Using RNAseq Data

Yan Guo, Leng Han, Shilin Zhao, 2015 .

Exome sequencing generates high quality data in non-target regions

J. Long, X. Shu, W. Zheng, 2012, BMC Genomics.

Finding the lost treasures in exome sequencing data.

Jiang Li, Y. Shyr, D. Samuels, 2013, Trends in genetics : TIG.

Evaluation of read count based RNAseq analysis methods

Y. Shyr, Yan Guo, Fei Ye, 2013, BMC Genomics.

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

A. Whittemore, S. Cross, M. Beckmann, 2016, PLoS medicine.

Multi-perspective quality control of Illumina exome sequencing data using QC3.

Jiang Li, Y. Shyr, D. Samuels, 2014, Genomics.

Mining diverse small RNA species in the deep transcriptome.

Yan Guo, Leng Han, K. Vickers, 2015, Trends in biochemical sciences.

Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.

Yan Guo, Yu Shyr, Dan M Roden, 2014, Journal of the American College of Cardiology.

The effect of strand bias in Illumina short-read sequencing data

Jiang Li, Yan Guo, Yu Shyr, 2012, BMC Genomics.

Current Research on Non-Coding Ribonucleic Acid (RNA)

D. Samuels, Yan Guo, Ying-yong Zhao, 2017, Genes.

Statistical strategies for microRNAseq batch effect reduction.

Yan Guo, Yu Shyr, Fei Ye, 2014, Translational cancer research.

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Yan Guo, Ben Zhang, Min-Ho Shin, 2014, Nature Genetics.

The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data

Y. Shyr, D. Samuels, Yan Guo, 2017, BMC Genomics.

Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells

T. Aune, P. Crooke, G. Shaginurova, 2017, The Journal of Immunology.

Right Ventricular Long Noncoding RNA Expression in Human Heart Failure

Yan Guo, E. Brittain, Y. Su, 2015, Pulmonary circulation.

Syddansk Universitet Preprocessing Significantly Improves the peptide / protein identification sensitivity of high-resolution isobarically labeled tandem mass spectrometry

R. Zeng, Y. Shyr, Yan Guo, 2015 .

Preprocessing Significantly Improves the Peptide/Protein Identification Sensitivity of High-resolution Isobarically Labeled Tandem Mass Spectrometry Data*

Chen Li, R. Zeng, Y. Shyr, 2014, Molecular & Cellular Proteomics.

Expression and functions of long noncoding RNAs during human T helper cell differentiation

T. Aune, P. Crooke, Yan Guo, 2015, Nature Communications.

Illumina human exome genotyping array clustering and quality control

J. Long, Y. Shyr, D. Samuels, 2014, Nature Protocols.

Altered ADAMTS 5 Expression and Versican Proteolysis : A Possible Molecular Mechanism in Barlow ’ s Disease Running Head : Down-regulation of ADAMTS 5 in Barlow ’ s disease

Atkinson, D. Sawyer, Yan Guo, 2017 .

Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas

K. Washington, Y. Shyr, W. El-Rifai, 2017, Scientific Reports.

A micro-RNA expression signature for human NAFLD progression

Yan Guo, Shilin Zhao, Y. Xiong, 2016, Journal of Gastroenterology.

RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining

X. Shu, Q. Cai, B. Lehmann, 2016, International journal of genomics.

Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing

Wanding Zhou, K. Vickers, Yan Guo, 2017, BMC Genomics.

MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia

Annette S. Kim, K. Vickers, Shaoying Li, 2017, Leukemia & lymphoma.

Practicability of detecting somatic point mutation from RNA high throughput sequencing data.

Y. Shyr, Yan Guo, Shilin Zhao, 2016, Genomics.

Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes

Annette S. Kim, K. Vickers, Yan Guo, 2015, BMC Genomics.

Mitochondria single nucleotide variation across six blood cell types.

Y. Shyr, D. Samuels, Yan Guo, 2016, Mitochondrion.

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

M. Ascano, R. Zhao, D. Cortez, 2015, Molecular and Cellular Biology.

O18Quant: A Semiautomatic Strategy for Quantitative Analysis of High-Resolution 16O/18O Labeled Data

R. Zeng, M. Miyagi, Yan Guo, 2014, BioMed research international.

Heterozygosity Ratio, a Robust Global Genomic Measure of Autozygosity and Its Association with Height and Disease Risk

W. Zheng, Y. Shyr, J. Capra, 2016, Genetics.

Estimating relative mitochondrial DNA copy number using high throughput sequencing data.

Y. Shyr, D. Samuels, B. Lehmann, 2017, Genomics.

Gene profiling the window of implantation: Microarray analyses from human and rodent models.

Yan Guo, B. Paria, J. Herington, 2016, Journal of reproductive health and medicine.

Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer.

A. Chak, J. Willis, S. Markowitz, 2019, Gastroenterology.

Hypoplastic Left Heart Syndrome Sequencing Reveals a Novel NOTCH1 Mutation in a Family with Single Ventricle Defects

D. Bichell, C. Hong, Yan Guo, 2017, Pediatric Cardiology.

Practicability of mitochondrial heteroplasmy detection through an Illumina genotyping array.

Y. Shyr, D. Samuels, Yan Guo, 2016, Mitochondrion.

Dynamics of Zebrafish Heart Regeneration Using an HPLC-ESI-MS/MS Approach.

Y. Shyr, Yan Guo, Q. Sheng, 2018, Journal of proteome research.

Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity

Yan Guo, S. Barkin, A. Non, 2017, BMC Genomics.

The use of next generation sequencing technology to study the effect of radiation therapy on mitochondrial DNA mutation.

Yan Guo, Yu Shyr, Fei Ye, 2012, Mutation research.

Advanced Heat Map and Clustering Analysis Using Heatmap3

Yan Guo, Quanhu Sheng, Yu Shyr, 2014, BioMed research international.

Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.

Y. Shyr, Yan Guo, N. Elliott, 2015, Leukemia research.

RnaSeqSampleSize: real data based sample size estimation for RNA sequencing

Yan Guo, Quanhu Sheng, Shyr Yu, 2018, BMC Bioinformatics.

Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data

Pan Zhang, Thomas Stricker, Shyr Yu, 2016, Briefings Bioinform..

High-throughput sequencing in mitochondrial DNA research.

Yan Guo, Fei Ye, David C Samuels, 2014, Mitochondrion.

MitoSeek: extracting mitochondria information and performing high-throughput mitochondria sequencing analysis

Jiang Li, Yan Guo, Shyr Yu, 2013, Bioinform..

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis.

W. El-Rifai, A. Corvalán, Zheng Li, 2019, Gastroenterology.

Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data

J. Long, Jiang Li, Bing Zhang, 2012, BMC Genomics.

Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis.

Yan Guo, Yu Shyr, David C Samuels, 2017, Genomics.

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

Bruce J. Aronow, Yu Shyr, Yina Li, 2012, Cell.

LMO2 induces T-cell leukemia with epigenetic deregulation of CD4.

Yan Guo, Yu Shyr, Y. Shyr, 2008, Experimental hematology.

The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer

S. Knapp, Ethan Lee, Lihong V Wang, 2016, Clinical Cancer Research.

Sample size calculation for differential expression analysis of RNA-seq data under Poisson distribution

Yan Guo, Shyr Yu, Pei-Fang Su, 2013, Int. J. Comput. Biol. Drug Des..

Cyclin‐dependent kinase 9–cyclin K functions in the replication stress response

Y. Shyr, R. Zhao, D. Cortez, 2010, EMBO reports.

Alternative applications for distinct RNA sequencing strategies

Yan Guo, Leng Han, David C. Samuels, 2015, Briefings Bioinform..

Power and sample size calculations for high-throughput sequencing-based experiments

Yan Guo, Shyr Yu, David C. Samuels, 2018, Briefings Bioinform..

Three-stage quality control strategies for DNA re-sequencing data

Yan Guo, Fei Ye, David C. Samuels, 2014, Briefings Bioinform..

RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas.

A. Chak, J. Willis, S. Markowitz, 2016, Cancer research.

Insight into the Etiology of Undifferentiated Soft Tissue Sarcomas from a Novel Mouse Model

Bingshan Li, Yan Guo, Quan Wang, 2019, Molecular Cancer Research.

Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted Therapies

V. Miller, Y. Shyr, A. Greenplate, 2018, JCO precision oncology.

RNAseqPS: A Web Tool for Estimating Sample Size and Power for RNAseq Experiment

Yan Guo, Quanhu Sheng, Yu Shyr, 2014, Cancer informatics.

Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing

W. McDonald, Yan Guo, W. Tansey, 2016, Proceedings of the National Academy of Sciences.

Heatmap3: an improved heatmap package with more powerful and convenient features

Yan Guo, Quanhu Sheng, Shyr Yu, 2014, BMC Bioinformatics.

Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue

J. Pietenpol, B. Lehmann, S. Morris, 2017, BMC Cancer.

The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies

Yan Guo, Yu Shyr, Y. Shyr, 2017, International journal of genomics.

A Cell-Based Systems Biology Assessment of Human Blood to Monitor Immune Responses after Influenza Vaccination

Yan Guo, Yu Shyr, Qi Liu, 2015, PloS one.

Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data

Gerard Tromp, Yan Guo, Marylyn D. Ritchie, 2013, PloS one.

Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells

Luke A. Torre-Healy, I. Nakano, Jing Liu, 2017, Stem Cell Reports.

Altered ADAMTS5 Expression and Versican Proteolysis: A Possible Molecular Mechanism in Barlow's Disease.

D. Sawyer, Yan Guo, J. Atkinson, 2017, The Annals of thoracic surgery.

Genome measures used for quality control are dependent on gene function and ancestry

Shyr Yu, Yan Guo, David C. Samuels, 2015, Bioinform..

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

A. Bardia, A. Guerrero-Zotano, J. Balko, 2019, Nature Communications.

A novel splice site mutation in SMARCAL1 results in aberrant exon definition in a child with schimke immunoosseous dysplasia

D. Cortez, Yan Guo, T. Hunley, 2015, American journal of medical genetics. Part A.

Evaluation of read count based RNAseq analysis methods

Y. Shyr, Yan Guo, Fei Ye, 2013, BMC Genomics.

Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes

Annette S. Kim, K. Vickers, Yan Guo, 2015, BMC Genomics.

Comparative Study of Exome Copy Number Variation Estimation Tools Using Array Comparative Genomic Hybridization as Control

Yan Guo, Yu Shyr, David C. Samuels, 2013, BioMed research international.

RNAseq by Total RNA Library Identifies Additional RNAs Compared to Poly(A) RNA Library

Y. Shyr, D. Samuels, J. Pietenpol, 2015, BioMed research international.

miR-378-3p Knockdown Recapitulates Many of the Features of Myelodysplastic Syndromes.

Annette S. Kim, Yan Guo, Sabin A. Nettles, 2021, The American journal of pathology.

Extramedullary leukemia behaving as solid cancer: clinical, histologic, and genetic clues to chemoresistance in organ sites

T. Shiomi, Y. Shyr, A. Papp, 2019, American journal of hematology.

Tgif1 Regulates Quiescence and Self-Renewal of Hematopoietic Stem Cells

Chun Xing Li, Y. Shyr, D. Wotton, 2013, Molecular and Cellular Biology.

Heatmap3: an improved heatmap package with more powerful and convenient features

Yan Guo, Shilin Zhao, Q. Sheng, 2014, BMC Bioinformatics.

Expression Profiling of Clinical Specimens Supports the Existence of Neural Progenitor‐Like Stem Cells in Basal Breast Cancers

W. Yarbrough, Yan Guo, A. Panaccione, 2017, Clinical breast cancer.

Strategies for processing and quality control of Illumina genotyping arrays

Yan Guo, Shyr Yu, David C. Samuels, 2018, Briefings Bioinform..

Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation

X. Chen, Y. Shyr, R. Hamid, 2015, Stem cells.

Very low-level heteroplasmy mtDNA variations are inherited in humans.

Q. Cai, Y. Shyr, Yan Guo, 2013, Journal of genetics and genomics = Yi chuan xue bao.

Sonic hedgehog pathway expression in non-small cell lung cancer

D. Carbone, Yan Guo, I. Csiki, 2012, Therapeutic advances in medical oncology.

Kinesin-5 inhibitor resistance is driven by kinesin-12

Stephen R. Norris, Yan Guo, R. Ohi, 2016, The Journal of cell biology.

An evaluation of allele frequency estimation accuracy using pooled sequencing data

Yan Guo, Wei Zheng, Jiang Li, 2013, Int. J. Comput. Biol. Drug Des..

Detection of Mitochondrial Mutations in Cancer by Next Generation Sequencing

Yan Guo, C. David, Samuels, 2014 .

Tri-allelic heteroplasmies, DNA-RNA differences and their polynucleotide tract associations in the mitochondrial genome.

Yan Guo, David C. Samuels, Shilin Zhao, 2017, Genomics.

Exome sequencing generates high quality data in non-target regions

J. Long, X. Shu, W. Zheng, 2012, BMC Genomics.

MultiRankSeq: Multiperspective Approach for RNAseq Differential Expression Analysis and Quality Control

Yan Guo, Quanhu Sheng, Yu Shyr, 2014, BioMed research international.

5-HT3 Signaling Alters Development of Sacral Neural Crest Derivatives That Innervate the Lower Urinary Tract

Yan Guo, Shilin Zhao, K. K. Deal, 2021, International journal of molecular sciences.

Effects of cancer-associated EPHA3 mutations on lung cancer.

Yu Shyr, Mark Boothby, Yan Guo, 2012, Journal of the National Cancer Institute.

LNK deficiency promotes acute aortic dissection and rupture.

J. Humphrey, Y. Shyr, Yan Guo, 2018, JCI insight.

Defective structural RNA processing in relapsing-remitting multiple sclerosis

T. Aune, P. Crooke, Yan Guo, 2015, Genome Biology.

Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing

Wanding Zhou, K. Vickers, Yan Guo, 2017, BMC Genomics.

Recent Advances in High Throughput Sequencing Analysis

Yan Guo, Leng Han, Quanhu Sheng, 2017, International journal of genomics.

The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data

Y. Shyr, D. Samuels, Yan Guo, 2017, BMC Genomics.

The effect of strand bias in Illumina short-read sequencing data

J. Long, Jiang Li, Y. Shyr, 2012, BMC Genomics.

Peripheral Blood Mitochondrial DNA Copy Number Obtained From Genome-Wide Genotype Data Is Associated With Neurocognitive Impairment in Persons With Chronic HIV Infection

R. Heaton, R. Ellis, J. Barnholtz-Sloan, 2019, Journal of acquired immune deficiency syndromes.

BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma

Yan Guo, C. Chiang, S. Borinstein, 2016, Oncotarget.

O18Quant: A Semiautomatic Strategy for Quantitative Analysis of High-Resolution 16O/18O Labeled Data

R. Zeng, M. Miyagi, Yan Guo, 2014, BioMed research international.

A comparison of microRNA sequencing reproducibility and noise reduction using mirVana and TRIzol isolation methods

Shyr Yu, Xue Zhong, Annette S. Kim, 2014, Int. J. Comput. Biol. Drug Des..

Genome-Wide Association Study of 58 Individuals with Fibrosing Mediastinitis Reveals Possible Underlying Genetic Susceptibility.

J. Cogan, Yan Guo, J. Loyd, 2017, American journal of respiratory and critical care medicine.

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Yan Guo, Yu Shyr, Nadia Solovieff, 2019, Nature Communications.

Bivariate Poisson models with varying offsets: an application to the paired mitochondrial DNA dataset

Y. Shyr, Qi Liu, Yan Guo, 2017, Statistical applications in genetics and molecular biology.

StrandScript: evaluation of Illumina genotyping array design and strand correction

Shyr Yu, Yan Guo, David C. Samuels, 2017, Bioinform..

RnaSeqSampleSize: real data based sample size estimation for RNA sequencing

Y. Shyr, Yan Guo, Shilin Zhao, 2018, BMC Bioinformatics.

Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation

X. Chen, Y. Shyr, R. Hamid, 2015, Stem cells.

Three-stage quality control strategies for DNA re-sequencing data

D. Samuels, Yan Guo, Fei Ye, 2014, Briefings Bioinform..

Power and sample size calculations for high-throughput sequencing-based experiments

D. Samuels, Yan Guo, Ying-yong Zhao, 2018, Briefings Bioinform..

LNK deficiency promotes acute aortic dissection and rupture.

J. Humphrey, Y. Shyr, Yan Guo, 2018, JCI insight.

Sonic hedgehog pathway expression in non-small cell lung cancer

D. Carbone, Yan Guo, I. Csiki, 2012, Therapeutic advances in medical oncology.

The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer

S. Knapp, Ethan Lee, Lihong V Wang, 2016, Clinical Cancer Research.

Detection of internal exon deletion with exon Del

Yan Guo, Quanhu Sheng, Thomas Stricker, 2014, BMC Bioinformatics.

High-throughput sequencing in mitochondrial DNA research.

D. Samuels, Yan Guo, Fei Ye, 2014, Mitochondrion.

The use of next generation sequencing technology to study the effect of radiation therapy on mitochondrial DNA mutation.

J. Boice, S. Levy, J. Long, 2012, Mutation research.

Population structure analysis on 2504 individuals across 26 ancestries using bioinformatics approaches

Yan Guo, Yu Shyr, David C Samuels, 2015, BMC Bioinformatics.