B. Phillips

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Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke

M. Peitsch, A. Sewer, J. Hoeng, 2020, Computational and structural biotechnology journal.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.

Rémi H. J. Dulize, M. Peitsch, J. Hoeng, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe−/− Mice—An Integrative Systems Toxicology Analysis

M. Peitsch, R. Laaksonen, J. Hoeng, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.

M. Peitsch, A. Sewer, J. Hoeng, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

M. Peitsch, J. Hoeng, Davide Sciuscio, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis

Rémi H. J. Dulize, M. Peitsch, B. Titz, 2020, Journal of Inflammation.

Other Compounds From Tobacco With Potential Impact on Neurodegenerative Diseases

M. Peitsch, J. Hoeng, B. Phillips, 2018 .

Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.

M. Peitsch, J. Hoeng, Davide Sciuscio, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Quantitative proteomics analysis using 2 D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modi fi ed risk tobacco product on the lung proteome in C 57 BL / 6 mice

M. Peitsch, J. Hoeng, Marcel Geertz, 2016 .

Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice.

M. Peitsch, J. Hoeng, Marcel Geertz, 2016, Journal of proteomics.

Structural, functional, and molecular impact on the cardiovascular system in ApoE-/- mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.

M. Peitsch, A. Sewer, J. Hoeng, 2019, Chemico-biological interactions.

Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe−/− mice – a systems toxicology analysis

Rémi H. J. Dulize, M. Peitsch, V. Belcastro, 2016, Inhalation toxicology.

A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared to cigarette smoke.

M. Peitsch, Ashutosh Kumar, A. Sewer, 2020, American journal of physiology. Heart and circulatory physiology.

A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract

John H. Miller, Rémi H. J. Dulize, M. Peitsch, 2021, Archives of Toxicology.

Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague–Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology

M. Peitsch, J. Hoeng, S. Boué, 2015, Inhalation toxicology.

State-of-the-art methods and devices for the generation, exposure, and collection of aerosols from heat-not-burn tobacco products

M. Peitsch, J. Hoeng, S. Boué, 2020 .

Research Models of Neurodegenerative Diseases: Major Considerations for Translatability

M. Peitsch, J. Hoeng, B. Phillips, 2018 .

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis

M. Peitsch, K. Luettich, J. Hoeng, 2022, Toxicology reports.

Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.

M. Peitsch, J. Hoeng, S. Boué, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Residual Risk of Nicotine

M. Peitsch, K. Luettich, J. Szostak, 2021 .

Assessment of ENDPs in Animal Models of Disease

M. Peitsch, K. Luettich, J. Hoeng, 2021 .

Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis

M. Peitsch, J. Hoeng, Davide Sciuscio, 2020, Archives of Toxicology.

Chapter 10 Animal Inhalation Models to Investigate Modulation of Inflammatory Bowel Diseases

M. Peitsch, J. Hoeng, B. Phillips, 2018 .

Animal Inhalation Models to Investigate Modulation of Inflammatory Bowel Diseases

M. Peitsch, J. Hoeng, B. Phillips, 2017 .

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/− Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes

Manuel C. Peitsch, Ashraf Elamin, Julia Hoeng, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Toxicological Assessment of ENDPs In Vivo

M. Peitsch, S. Boué, B. Phillips, 2021 .

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

Rémi H. J. Dulize, M. Peitsch, A. Sewer, 2020, Scientific Reports.

A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.

Ashraf Elamin, Julia Hoeng, Marja Talikka, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

In Vivo Profiling of a Natural Alkaloid, Anatabine, in Rodents: Pharmacokinetics and Anti-Inflammatory Efficacy.

M. Peitsch, J. Hoeng, K. Koshibu, 2021, Journal of Natural Products.

Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract

M. Peitsch, J. Hoeng, J. Szostak, 2021, Frontiers in Microbiology.

Ceramide ratios are affected by cigarette smoke but not heat-not-burn or e-vapor aerosols across four independent mouse studies.

M. Peitsch, J. Hoeng, B. Titz, 2020, Life sciences.

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice

Manuel C. Peitsch, Kim Ekroos, Ashraf Elamin, 2016, Scientific Data.

Long term exposure to cigarette smoke impacts genes involved in cardiac muscle structure and function in Apoe−/− mouse while exposure to the aerosol does not

M. Peitsch, J. Hoeng, S. Boué, 2016 .

Ashraf Elamin, Julia Hoeng, Marja Talikka, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

State-of-the-art methods and devices for generation, exposure, and collection of aerosols from e-vapor products