D. Erle

发表

Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD

S. Dahlén, D. Balgoma, Å. Wheelock, 2016, European Respiratory Journal.

IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production.

David J Erle, D. Erle, G. Zhen, 2007, American journal of respiratory cell and molecular biology.

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Yee Hwa Yang, Keith R. Yamamoto, Homer A. Boushey, 2007, Proceedings of the National Academy of Sciences.

Asthmatics with exacerbation during acute respiratory illness exhibit unique transcriptional signatures within the nasal mucosa

H. Boushey, D. Erle, P. Avila, 2014, Genome Medicine.

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

Sebastian Amigorena, Matthew F Krummel, Bijan Boldajipour, 2014, Cancer cell.

Spotted long oligonucleotide arrays for human gene expression analysis.

Kristina Hanspers, Terence P Speed, Benjamin M Bolstad, 2003, Genome research.

Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph.

C. Mackay, E. Butcher, D. Erle, 1996, Journal of immunology.

Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow.

D. Erle, M. Gunn, R. Pachynski, 1998, Journal of immunology.

Disease-specific gene expression profiling in multiple models of lung disease.

D. Voehringer, D. McDonald, J. Yang, 2008, American journal of respiratory and critical care medicine.

Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1.

J. Olgin, G. Marcus, D. Erle, 2013, Cardiovascular research.

Global Absence and Targeting of Protective Immune States in Severe COVID-19

Chun Jimmie Ye, Gabriela K. Fragiadakis, A. Rao, 2020, bioRxiv.

Global Absence and Targeting of Protective Immune States in Severe COVID-19.

Chun Jimmie Ye, Gabriela K. Fragiadakis, Kamir J. Hiam, 2020, Research square.

Inflammation in an Asthma Model Increases Airway Reactivity and Regulates Airway Surface Liquid, and Infection, Induced by Allergy and Rhinovirus The Epithelial Anion Transporter Pendrin Is

H. Boushey, Y. Nakagami, D. Erle, 2008 .

Tissue signals imprint ILC2 identity with anticipatory function

R. Locksley, Dedeepya Vaka, D. Erle, 2018, Nature Immunology.

Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma.

Yongjian Xu, D. Erle, Jianping Zhao, 2014, American journal of respiratory and critical care medicine.

Flow cytometric analysis and purification of airway epithelial cell subsets

D. Erle, W. Eckalbar, W. Finkbeiner, 2020, bioRxiv.

An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup

Meilan K. Han, J. Curtis, R. Bowler, 2018, The Journal of clinical investigation.

COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone

N. Neff, J. Derisi, M. Sirota, 2021, Research square.

Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD

Å. Wheelock, C. Wheelock, Mingxing Yang, 2017, European Respiratory Journal.

An airway epithelial IL-17 A response signature identifies a steroid-unresponsive COPD patient

J. Curtis, R. Bowler, E. Bleecker, 2018 .

Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma.

D. Erle, W. Finkbeiner, L. Zlock, 2016, The Journal of clinical investigation.

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling (vol 36, pg 746, 2018)

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

Immediate myeloid depot for SARS-CoV-2 in the human lung

M. Ott, D. Erle, P. Woodruff, 2022, Research square.

Immediate myeloid depot for SARS-CoV-2 in the human lung

M. Ott, M. Matthay, D. Erle, 2022, bioRxiv.

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Mark S. Anderson, Chun Jimmie Ye, Gabriela K. Fragiadakis, 2022, Science immunology.

Recent advances in molecular biological techniques and their relevance to pulmonary research

W. Parks, S. Albelda, D. Erle, 2000, Thorax.

Mapping the 17q12-21.1 Locus for Variants Associated with Early-onset Asthma in African Americans.

G. Abecasis, H. Kang, H. Hakonarson, 2020, American journal of respiratory and critical care medicine.

Polymerase chain reaction cloning with degenerate primers: homology-based identification of adhesion molecules.

D. Sheppard, J. Breuss, D. Erle, 1994, Methods in enzymology.

Genomics and proteomics of lung disease: conference summary.

John Quackenbush, Naftali Kaminski, Scott T Weiss, 2007, American journal of physiology. Lung cellular and molecular physiology.

Apolipoprotein A1 potentiates lipoxin A4 synthesis and recovery of allergen‐induced disrupted tight junctions in the airway epithelium

S. Uh, D. Erle, A. Jang, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.

D. Corry, D. Erle, G. Grünig, 2002, American journal of respiratory cell and molecular biology.

Tissue‐selective mast cell reconstitution and differential lung gene expression in mast cell‐deficient KitW‐sh/KitW‐sh sash mice

P. Wolters, D. Erle, P. Baluk, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effect of serial-day exposure to nitrogen dioxide on airway and blood leukocytes and lymphocyte subsets.

M. Kleinman, J. Balmes, D. Erle, 2000, The European respiratory journal.

CRISPR–Cas9-mediated functional dissection of 3′-UTRs

N. Ahituv, N. Zaitlen, D. Erle, 2017, Nucleic acids research.

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

E. Butcher, C. Rüegg, D. Erle, 1992, Journal of Cell Biology.

Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression.

D. Erle, R. Aris, D. Christian, 1994, American journal of respiratory cell and molecular biology.

Airway Mucus and Asthma: The Role of MUC5AC and MUC5B

D. Erle, L. Bonser, 2017, Journal of clinical medicine.

Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types.

N. Kaminski, D. Sheppard, D. Erle, 2001, American journal of respiratory cell and molecular biology.

Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

Gabriela K. Fragiadakis, R. Dewar, A. Beagle, 2022, Critical Care.

Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients

Stanley J Tamaki, S. Asthana, S. Darmanis, 2022, Immunity.

Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.

Y. Nakagami, D. Erle, P. Woodruff, 2009, American journal of respiratory and critical care medicine.

Productionfor Allergen-Induced Mucus IL-4 Receptor Signaling in Clara Cells Is

D. Erle, F. Brombacher, Xiaozhu Huang, 2017 .

Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma.

D. Erle, F. Brombacher, A. Lopata, 2010, The Journal of allergy and clinical immunology.

A distinctive alveolar macrophage activation state induced by cigarette smoking.

Y. H. Yang, D. Erle, P. Woodruff, 2005, American journal of respiratory and critical care medicine.

Integrin b 6 Mediates Phospholipid and Collectin Homeostasis by Activation of Latent TGF- b 1

David G. Morris, D. Sheppard, D. Erle, 2007 .

Preferential production of interferon‐γ by CD4+ T cells expressing the homing receptor integrin α4/β7

D. Erle, S. Qiu, O. Abramson, 2001 .

Influenza Virus Infection Causes Global Respiratory Tract B Cell Response Modulation via Innate Immune Signals

D. Erle, N. Baumgarth, Yu-Ling Xiao, 2007 .

Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes.

E. Butcher, D. Erle, A. García-Pardo, 1994, Journal of immunology.

CD11b+ Myeloid Cells Are the Key Mediators of Th2 Cell Homing into the Airway in Allergic Inflammation1

B. Medoff, J. Duffield, D. Erle, 2009, The Journal of Immunology.

Airway in Allergic Inflammation Mediators of Th2 Cell Homing into the Myeloid Cells Are the Key + CD11b

B. Medoff, J. Duffield, D. Erle, 2008 .

rNA-seq methods for quantitative mirNA profiling

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

Progress toward a systems biology approach to acute lung injury.

D. Erle, J. Frank, 2007, American journal of physiology. Lung cellular and molecular physiology.

IFN‐stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma

J. Derisi, D. Erle, P. Woodruff, 2017, American journal of respiratory and critical care medicine.

Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol

D. Erle, A. Khosravi, 2016, PloS one.

IL-17 and "TH2-high" asthma: Adding fuel to the fire?

D. Erle, N. Bhakta, 2014, The Journal of allergy and clinical immunology.

The asthma channel? Stay tuned . . .

D. Erle, G. Zhen, 2006, American journal of respiratory and critical care medicine.

Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.

D. Erle, G. Zhen, Zhen-xiang Zhang, 2010, American journal of physiology. Lung cellular and molecular physiology.

Intraepithelial lymphocytes in the lung: a neglected lymphocyte population.

D. Erle, R. Pabst, Reinhard Pabst, 2000, American journal of respiratory cell and molecular biology.

Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1.

E. Butcher, D. Erle, T. Yednock, 1997, Journal of immunology.

Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.

P. Rosenthal, J. Cyster, D. Erle, 2013, The Journal of clinical investigation.

Delayed Goblet Cell Hyperplasia, Acetylcholine Receptor Expression, and Worm Expulsion in SMC-Specific IL-4Rα–Deficient Mice

F. Finkelman, G. Owens, D. Erle, 2007, PLoS pathogens.

Activated α4 Integrins are Preferentially Expressed on Immature Thymocytes and Activated T Cells

J. Kearney, F. Seibold, D. Erle, 2002, Developmental immunology.

How do integrins integrate? The role of cell adhesion receptors in differentiation and development.

D. Erle, R. Pytela, 1992, American journal of respiratory cell and molecular biology.

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

D. Sheppard, D. Erle, G. Dolganov, 2002, Nature Medicine.

Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.

E. Verdin, D. Erle, J. Zikherman, 2017, Cell reports.

Putting Mucins on the Map

D. Erle, L. Bonser, 2019, American journal of respiratory and critical care medicine.

The airway epithelium in asthma.

D. Erle, L. Bonser, 2019, Advances in immunology.

Airway epithelial miRNA expression is altered in asthma.

M. Love, K. Ansel, M. Solon, 2012, American journal of respiratory and critical care medicine.

Novel integrin α and β subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction

D. Sheppard, C. Rüegg, J. Breuss, 1991 .

Identification of novel airway epithelial integrins using the homology-based polymerase chain reaction.

D. Sheppard, D. Erle, R. Pytela, 1992, Chest.

Preferential production of interferon-gamma by CD4+ T cells expressing the homing receptor integrin alpha4/beta7.

D. Erle, O. Abramson, S. Qiu, 2001, Immunology.

Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2

R. Andino, B. Shoichet, X. Shu, 2023, Nature Microbiology.

Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit

Mark S. Anderson, Miranda R Lyons-Cohen, R. Locksley, 2018, bioRxiv.

Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease

R. Locksley, P. Wolters, D. Erle, 2017, Cell.

The Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway.

Lisa A. Ostrin, D. Erle, M. Salathe, 2015, American journal of respiratory cell and molecular biology.

The Type 2 Asthma Mediator IL-13 Inhibits Severe Acute Respiratory Syndrome Coronavirus 2 Infection of Bronchial Epithelium

D. Erle, P. Woodruff, W. Eckalbar, 2022, American Journal of Respiratory Cell and Molecular Biology.

Integrin β Cytoplasmic Domains Differentially Bind to Cytoskeletal Proteins*

D. Erle, M. Ginsberg, M. Pfaff, 1998, The Journal of Biological Chemistry.

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.

Sebastian Amigorena, Matthew F Krummel, Bijan Boldajipour, 2014, Cancer cell.

A Pan-Cancer Census of Dominant Tumor Immune Archetypes

A. Olshen, S. Asthana, E. Collisson, 2021, bioRxiv.

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

Hongyu Zhao, R. Andino, P. Natarajan, 2020, Cell Stem Cell.

The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model1

H. Boushey, Y. Nakagami, D. Erle, 2008, The Journal of Immunology.

cytoskeletal events, and soft glasses The first three minutes: smooth muscle contraction,

J. Fredberg, S. Gunst, D. Erle, 2015 .

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin

Robert V Farese, S. Young, D. Sheppard, 1996, The Journal of cell biology.

MPRAudit Quantifies the Fraction of Variance Described by Unknown Features in Massively Parallel Reporter Assays

Noah Zaitlen, Anne Biton, David J. Erle, 2020, bioRxiv.

Thymic tuft cells promote an IL4-enriched medulla and shape thymocyte development

Mark S. Anderson, L. Steinmetz, R. Locksley, 2018, Nature.

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

Michael T. McManus, E. Kremmer, A. Rao, 2013, The Journal of experimental medicine.

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Mark S. Anderson, L. Steinmetz, R. Locksley, 2018, Nature.

Widespread Effects of Chemokine 3′ Untranslated Regions on mRNA Degradation and Protein Production in Human Cells

D. Erle, Wenxue Zhao, 2018, The Journal of Immunology.

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling (vol 36, pg 746, 2018)

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

Comprehensive multi-center assessment of accuracy, reproducibility and bias of small RNA-seq methods for quantitative miRNA profiling

Renee Rubio, David Baxter, Hui Jiang, 2018 .

Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

E. Seeley, M. Matthay, D. Erle, 2015, American journal of physiology. Lung cellular and molecular physiology.

Abnormal alveolar development associated with elevated adenine nucleosides.

D. Erle, A. Barczak, M. Blackburn, 2004, American journal of respiratory cell and molecular biology.

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

Nikita A. Sakhanenko, Michael T. McManus, Andrew R. Jackson, 2019, Cell.

Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma

N. Ahituv, D. Erle, Ofer Yizhar-Barnea, 2022, Cell genomics.

Discovering dominant tumor immune archetypes in a pan-cancer census

E. Nakakura, A. Olshen, S. Asthana, 2021, Cell.

Toward a systematic understanding of mRNA 3' untranslated regions.

D. Erle, D. Blagev, Joshua L. Pollack, 2011, Proceedings of the American Thoracic Society.

Systemically dispersed innate IL-13–expressing cells in type 2 immunity

David J. Erle, R. Locksley, D. Erle, 2010, Proceedings of the National Academy of Sciences.

Large Differences in Small RNA Composition Between Human Biofluids

T. Patel, S. Fisher, R. Price, 2018, bioRxiv.

A global map of RNA binding protein occupancy guides functional dissection of post-transcriptional regulation of the T cell transcriptome

N. Zaitlen, K. Ansel, D. Erle, 2018, bioRxiv.

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01

Xiaomin Wang, M. Holtgrewe, D. Beule, 2021, EClinicalMedicine.

Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells

Michael T. McManus, Mark S. Anderson, G. Passos, 2015, PloS one.

Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands 1

N. Killeen, D. Erle, A. Barczak, 2009, The Journal of Immunology.

Inactivation of the Integrin [36 Subunit Gene Reveals a Role of Epithelial Integrins in Regulating Inflammation in the Lungs and Skin

Robert V Farese, S. Young, D. Sheppard, 2002 .

Epithelial miR-141 regulates IL-13–induced airway mucus production

A. Marson, K. Ansel, Theodore L. Roth, 2021, JCI insight.

Steps toward Cell Therapy for Cystic Fibrosis

D. Erle, Kyung Duk Koh, 2020, American journal of respiratory cell and molecular biology.

Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.

Yuanyuan Xiao, David Jablons, Kirk Jones, 2007, The Journal of clinical investigation.

Global absence and targeting of protective immune states in severe COVID-19

Chun Jimmie Ye, A. Rao, M. Wilson, 2021, Nature.

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

D. Sheppard, D. Erle, Yanli Wang, 2012, The Journal of clinical investigation.

Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

B. Rollins, D. Erle, Madeleine W Rodriguez, 2004, Respiratory research.

A tissue checkpoint regulates type 2 immunity

Chun Jimmie Ye, R. Locksley, A. Marson, 2016, Nature Immunology.

Comparison of Reproducibility, Accuracy, Sensitivity, and Specificity of miRNA Quantification Platforms

D. Galas, L. Laurent, Saumya Das, 2019, Cell reports.

Comparison of miRNA profiling methods using synthetic miRNA pools and standardized exRNA samples reveals substantial performance differences

L. Laurent, Saumya Das, D. Erle, 2019, bioRxiv.

The Type 2 Asthma Mediator IL-13 Inhibits SARS-CoV-2 Infection of Bronchial Epithelium.

D. Erle, P. Woodruff, W. Eckalbar, 2022, American journal of respiratory cell and molecular biology.

Integrin β6 Mediates Phospholipid and Collectin Homeostasis by Activation of Latent TGF-β1

D. Sheppard, D. Erle, D. G. Morris, 2007 .

Correction: Delayed Goblet Cell Hyperplasia, Acetylcholine Receptor Expression, and Worm Expulsion in SMC-Specific IL-4Rα–Deficient Mice

F. Finkelman, G. Owens, D. Erle, 2007, PLoS Pathogens.

Influenza Virus Infection Causes Global Respiratory Tract B Cell Response Modulation via Innate Immune Signals1

D. Erle, Yuanyuan Xiao, N. Baumgarth, 2007, The Journal of Immunology.

Modulation via Innate Immune Signals Respiratory Tract B Cell Response Influenza Virus Infection Causes Global

D. Erle, Yuanyuan Xiao, N. Baumgarth, 2007 .

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

Yasuhiro Nakagami, Sung-Woo Park, Andrea J Barczak, 2009, Proceedings of the National Academy of Sciences.

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19

Mark S. Anderson, Chun Jimmie Ye, Yun S. Song, 2021, Science Translational Medicine.

Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19

Mark S. Anderson, Chun Jimmie Ye, Yun S. Song, 2021, bioRxiv.

Whole Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.

Kevin L. Keys, G. Abecasis, H. Kang, 2020, American journal of respiratory and critical care medicine.

Targeting a central feature of asthma using a cell type-selective IL-13-responsive enhancer

N. Ahituv, D. Erle, Ofer Yizhar-Barnea, 2021, bioRxiv.

Hands-on Workshops as An Effective Means of Learning Advanced Technologies Including Genomics, Proteomics and Bioinformatics

Katerina Kechris, Alexey I. Nesvizhskii, Richard Reisdorph, 2013, Genom. Proteom. Bioinform..

The cell biology of asthma

D. Sheppard, D. Erle, 2014, The Journal of cell biology.

Massively parallel analysis of human 3′ UTRs reveals that AU-rich element length and registration predict mRNA destabilization

N. Zaitlen, D. Erle, A. Biton, 2020, bioRxiv.

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

Michael T. McManus, K. Ansel, D. Erle, 2016, Immunity.

Massively parallel functional annotation of 3' untranslated regions

Michael T. McManus, Noah Zaitlen, David J. Erle, 2014, Nature Biotechnology.

Increased DNA microarray hybridization specificity using sscDNA targets

K. Hanspers, J. Yang, D. Erle, 2005, BMC Genomics.

COVID-19–associated Lung Microvascular Endotheliopathy: A “From the Bench” Perspective

M. Matthay, D. Erle, P. Woodruff, 2022, American journal of respiratory and critical care medicine.

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients.

S. Gabrielsson, M. Svartengren, Å. Wheelock, 2013, The Journal of allergy and clinical immunology.

IL-4 Receptor Signaling in Clara Cells Is Required for Allergen-Induced Mucus Production1

D. Erle, F. Brombacher, Louis T. Nguyenvu, 2005, The Journal of Immunology.

A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization

K. Ansel, H. Goodarzi, D. Erle, 2019, Genome research.

Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease

O. Brand, Yifan Cheng, P. Wolters, 2014, Science Translational Medicine.

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

E. Butcher, C. Rüegg, A. Postigo, 1992, The Journal of cell biology.

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

M. Ott, D. Jablons, M. Matthay, 2021 .

The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile

K. Shokat, D. Erle, R. Barbeau, 2011, Proceedings of the National Academy of Sciences.

Intelectin contributes to allergen-induced IL-25, IL-33 and TSLP expression and type 2 response in asthma and atopic dermatitis

D. Erle, Jianping Zhao, G. Zhen, 2017, Mucosal Immunology.

miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis

H. Collard, J. Golden, K. Jones, 2016, PloS one.

Secondary Lymphoid-Tissue Chemokine (SLC) Stimulates Integrin α4β7-Mediated Adhesion of Lymphocytes to Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1) Under Flow

D. Erle, M. Gunn, R. Pachynski, 1998, The Journal of Immunology.

A conserved immune trajectory of recovery in hospitalized COVID-19 patients

Stanley J Tamaki, M. Spitzer, K. Ansel, 2022, bioRxiv.

The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epithelium

D. Erle, P. Woodruff, W. Eckalbar, 2021, bioRxiv.

The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses

Mark S. Anderson, M. Waterfield, D. Erle, 2019, The Journal of experimental medicine.

Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study

Jordan L. Metcalf, Ruth R. Montgomery, Matthew C. Altman, 2021, Science immunology.

Efficient RNP-directed human gene targeting reveals SPDEF is required for IL-13-induced mucostasis

D. Erle, P. Woodruff, W. Finkbeiner, 2019, bioRxiv.

CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4+ Thymocytes and Supports Development of Natural Regulatory T Cells

D. Erle, R. Barbeau, A. Barczak, 2018, The Journal of Immunology.

Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling

Ryan M Spengler, D. Galas, L. Laurent, 2018, Nature Biotechnology.

Impaired antibacterial immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19

N. Neff, J. Derisi, S. Darmanis, 2021, medRxiv.

Integrative approach identifies corticosteroid response variant in diverse populations with asthma

P. Kwok, E. Burchard, M. Pino-Yanes, 2019, Journal of Allergy and Clinical Immunology.

Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.

Y. Tanaka, D. Erle, K. Horgan, 1993, Journal of immunology.

Dissecting asthma using focused transgenic modeling and functional genomics.

Y. H. Yang, D. Erle, P. Woodruff, 2005, The Journal of allergy and clinical immunology.

AGR2 is induced in asthma and promotes allergen-induced mucin overproduction.

D. Erle, G. Zhen, Louis T. Nguyenvu, 2012, American journal of respiratory cell and molecular biology.

Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes.

D. Sheppard, C. Rüegg, D. Erle, 1991, The Journal of biological chemistry.

Library Preparation for small RNA sequencing using 4N adapters: In house 4N Protocol C

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

Modified TruSeq Small RNA Library Prep using Randomized 4N Adapters: In house 4N Protocol D

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

An Engineered Cardiac Reporter Cell Line Identifies Human Embryonic Stem Cell-Derived Myocardial Precursors

D. Erle, Carissa Ritner, S. Mihardja, 2011, PloS one.

Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking

D. Littman, N. Killeen, D. Erle, 2009, PloS one.

Abstract B65: Dissecting the tumor myeloid compartment reveals rare activating antigen presenting cells, critical for T cell immunity

D. Barber, D. Wolf, A. Daud, 2015 .

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

A. Sigal, I. Nazarenko, M. Ott, 2023, Stem Cell Reports.

Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

V. Quaranta, D. Sheppard, D. Erle, 1990, The Journal of biological chemistry.

Distinct Roles of FOXA2 and FOXA3 in Allergic Airway Disease.

D. Erle, Louis T. Nguyenvu, C. Eisley, 2009, ATS 2009.

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Mark S. Anderson, M. Waterfield, D. Erle, 2014, Nature Immunology.

Differences In Exosomal Micrornas In Bronchoalveolar Lavage Fluid From Asthmatics And Healthy Individuals

S. Gabrielsson, M. Svartengren, Å. Wheelock, 2011, ATS 2011.

Effect of exercise rate and route of inhalation on sulfur-dioxide-induced bronchoconstriction in asthmatic subjects.

H. Boushey, J. Nadel, D. Erle, 2015, The American review of respiratory disease.

Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

Susumu Goto, Åsa M Wheelock, Craig E Wheelock, 2012, BMC Medical Genomics.

Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19

N. Neff, J. Derisi, S. Darmanis, 2021, Research square.

Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19

Chun Jimmie Ye, A. Rao, M. Wilson, 2021, Nature.

Presentation of Integrins on Leukocyte Microvilli: A Role for the Extracellular Domain in Determining Membrane Localization

Mark Tidswell, David J. Erle, D. Erle, 1997, The Journal of cell biology.

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

M. Ott, D. Jablons, M. Matthay, 2021, bioRxiv.

Differential gene expression by integrin β7+ and β7- memory T helper cells

Yee Hwa Yang, David J Erle, Y. H. Yang, 2004, BMC Immunology.

Asthma investigators begin to reap the fruits of genomics

Y. H. Yang, D. Erle, 2003, Genome Biology.

COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and may be modified by dexamethasone

J. Derisi, M. Sirota, A. Pisco, 2021, medRxiv.

Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program

G. Abecasis, H. Kang, H. Hakonarson, 2020, PloS one.

Role ofIntegrina4ß7/a4ßPinLymphocyteAdherenceto Fibronectin and VCAM4 and inHomotypicCellClustering

E. Butcher, D. Erle, Antonio A. Pbstigo, 1992 .

Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1.

D. Sheppard, D. Erle, D. G. Morris, 2007, American journal of respiratory cell and molecular biology.

Novel integrin alpha and beta subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction.

D. Sheppard, C. Rüegg, J. Breuss, 1991, American journal of respiratory cell and molecular biology.

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS

Kenneth T. Hu, Kamir J. Hiam, N. Neff, 2021, Nature Communications.

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity [published erratum appears in J Exp Med 1997 May 5;185(9):1715]

R. Locksley, D. Corry, H. Folkesson, 1996, The Journal of experimental medicine.

Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19

D. Erle, P. Woodruff, W. Eckalbar, 2023, Research square.

Comprehensive multi-center assessment of accuracy, reproducibility and bias of small RNA-seq methods for quantitative miRNA profiling

Ryan M Spengler, D. Galas, L. Laurent, 2018, Nature Biotechnology.

rNA-seq methods for quantitative mirNA profiling

Ryan M Spengler, D. Galas, L. Laurent, 2018 .

Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

E. Seeley, M. Matthay, D. Erle, 2015, American journal of physiology. Lung cellular and molecular physiology.

Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD

C. Wheelock, Mingxing Yang, S. Snowden, 2017, European Respiratory Journal.

Singling out Th2 cells in eosinophilic esophagitis.

D. Erle, W. Eckalbar, 2019, The Journal of clinical investigation.

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

A. Sigal, M. Ott, D. Jablons, 2023, Stem cell reports.

Stem Cell Repor ts

A. Sigal, A. Rao, I. Nazarenko, 2023 .

Stem Cell Repor ts

A. Sigal, A. Rao, I. Nazarenko, 2022 .

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Mark S. Anderson, M. Waterfield, D. Erle, 2014, Nature Immunology.

Intraepithelial Lymphocytes: Scratching the surface

D. Erle, D. Erle, 1995, Current Biology.

An integrated nano-scale approach to profile miRNAs in limited clinical samples.

R. Djukanović, K. Ansel, R. Blelloch, 2012, American journal of clinical and experimental immunology.

The cell biology of asthma

D. Sheppard, D. Erle, 2014, The Journal of cell biology.

Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma.

D. Erle, W. Finkbeiner, L. Zlock, 2016, The Journal of clinical investigation.

Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.

D. Erle, G. Zhen, Zhen-xiang Zhang, 2010, American journal of physiology. Lung cellular and molecular physiology.

CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS

E. Seeley, M. Matthay, D. Erle, 2015 .

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients.

S. Gabrielsson, M. Svartengren, Bettina Levänen, 2013, The Journal of allergy and clinical immunology.

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.

D. Barber, D. Wolf, A. Daud, 2014, Cancer cell.

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

Nikita A. Sakhanenko, Michael T. McManus, Andrew R. Jackson, 2019, Cell.

Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.

P. Rosenthal, J. Cyster, D. Erle, 2013, The Journal of clinical investigation.

Stem Cell Repor ts

A. Sigal, D. Jablons, D. Erle, 2023 .

Stem Cell Repor ts

A. Sigal, D. Jablons, D. Erle, 2023 .

Stem Cell Repor ts

A. Sigal, D. Jablons, D. Erle, 2023 .

Expression of IL-4 Receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma

D. Erle, F. Brombacher, A. Lopata, 2010 .

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity [published erratum appears in J Exp Med 1997 May 5;185(9):1715]

R. Locksley, J. Erie, D. Corry, 1996, The Journal of experimental medicine.

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

D. Sheppard, D. Erle, Yanli Wang, 2012, The Journal of clinical investigation.

Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD

S. Dahlén, D. Balgoma, Å. Wheelock, 2016, European Respiratory Journal.

inflammation and

Robert V Farese, S. Young, D. Sheppard, 2002 .

Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

B. Pulendran, H. van Bakel, O. Levy, 2024, Nature communications.

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Mark S. Anderson, Chun Jimmie Ye, P. Gregersen, 2022, Science Immunology.

Global Absence and Targeting of Protective Immune States in Severe COVID-19.

D. Erle, C. Calfee, M. Looney, 2020, Research square.

Immediate myeloid depot for SARS-CoV-2 in the human lung

D. Erle, P. Woodruff, C. Calfee, 2024, Science advances.

GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

K. Ansel, D. Erle, K. Taylor, 2023, Genome Biology.

Massively Parallel Analysis of Human 3 (cid:48) UTRs Reveals that AU-Rich Element Length and Registration Predict mRNA Destabilization

N. Zaitlen, D. Erle, ∗. DavidA.Siegel, 2022 .

CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS

D. Erle, C. Calfee, K. Kangelaris, 2015 .

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering.

D. Erle, R. Pytela, E. Sikorski, 2002 .

Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia

Katrina L Kalantar, D. Erle, C. Calfee, 2024, Nature communications.