M. K. Bach

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Slow-reacting substances (leukotrienes) contract human airway and pulmonary vascular smooth muscle in vitro

P. Paré, C. J. Hanna, M. K. Bach, 1981, Nature.

Inhibition of the leukotriene synthetase of rat basophil leukemia cells by diethylcarbamazine, and synergism between diethylcarbamazine and piriprost, a 5-lipoxygenase inhibitor.

M. K. Bach, J. R. Brashler, 1986, Biochemical pharmacology.

Auxins and their Effection the Growth of Unicellular Algae: Effect of Ethanol and Auxins on the Growth of Unicellular Algae

M. K. Bach, J. Fellig, 1958, Nature.

Inhibition by sulfasalazine of LTC synthetase and of rat liver glutathione S-transferases.

M. K. Bach, M. Johnson, J. R. Brashler, 1985, Biochemical pharmacology.

Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: a novel, particulate glutathione S-transferase.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, Archives of biochemistry and biophysics.

Leukotriene C synthetase, a special glutathione S-transferase: properties of the enzyme and inhibitor studies with special reference to the mode of action of U-60,257, a selective inhibitor of leukotriene synthesis.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, The Journal of allergy and clinical immunology.

Superoxide production by human eosinophils can be inhibited in an agonist-selective manner

M. K. Bach, M. Sanders, M. E. Sanders, 2005, Agents and Actions.

Pitfalls in the quantitative estimation of the secretion of granule proteins by eosinophils.

M. K. Bach, M. Sanders, M. Bienkowski, 1991, Journal of immunological methods.

Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma.

S. Holgate, M. K. Bach, C. Robinson, 1986, Thorax.

The activity of a new, novel inhibitor of leukotriene synthesis in rhesus monkey Ascaris reactors.

M. K. Bach, H. Smith, H. G. Johnson, 1983, International archives of allergy and applied immunology.

Inhibition of the presumably leukotriene-dependent component of antigen-induced bronchoconstriction in the guinea pig by piriprost (U-60,257).

M. K. Bach, R. Griffin, I. M. Richards, 1985, International archives of allergy and applied immunology.

Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro.

J. Shelhamer, M. Kaliner, M. K. Bach, 2015, The American review of respiratory disease.

Evidence that granulocyte/macrophage-colony-stimulating factor and interferon-gamma maintain the viability of human peripheral blood monocytes in part by their suppression of IL-10 production.

M. K. Bach, J. R. Brashler, 1995, International archives of allergy and immunology.

IgE immune complexes induce immediate and prolonged release of leukotriene C4 (LTC4) from rat alveolar macrophages.

P. Askenase, M. K. Bach, J. Rankin, 1984, Journal of immunology.

IgE-dependent release of leukotriene C4 from alveolar macrophages

P. Askenase, M. K. Bach, J. Rankin, 1982, Nature.

On the structure of slow reacting substance of anaphylaxis: evidence of biosynthesis from arachidonic acid.

M. K. Bach, R. Gorman, J. R. Brashler, 1977, Prostaglandins.

Determination of leukotriene C4 by radioimmunoassay with a specific antiserum generated from a synthetic hapten mimic.

M. K. Bach, F. Fitzpatrick, D. R. Morton, 1984, Analytical chemistry.

Slow reacting substances: comparison of some properties of human lung SRS-A and two distinct fractions from ionophore-induced rat mononuclear cell SRS.

M. K. Bach, J. R. Brashler, C. D. Brooks, 1979, Journal of immunology.

The Effects of Arachinoids and Leukotrienes on the Release of Mucus from Human Airways

J. Shelhamer, M. Kaliner, M. K. Bach, 1982 .

Hyperreactivity of airways smooth muscle produced in vitro by leukotrienes.

M. K. Bach, B. Creese, 1983, Prostaglandins, leukotrienes, and medicine.

Identification of leukotriene C-1 as a major component of slow-reacting substance from rat mononuclear cells.

B. Samuelsson, M. K. Bach, J. R. Brashler, 1980, Journal of immunology.

Identification of a component of rat mononuclear cell SRS as leukotriene D.

B. Samuelsson, M. K. Bach, J. R. Brashler, 1980, Biochemical and biophysical research communications.

Ionophore A 23187-induced production of slow reacting substance of anaphylaxis (SRS-A) by rat peritoneal cells in vitro: evidence for production by mononuclear cells.

M. K. Bach, J. R. Brashler, 1978, Journal of immunology.

Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.

M. K. Bach, F. Fitzpatrick, B. Creese, 1984, European journal of pharmacology.

6 – Inhibitors of Leukotriene Synthesis and Action

M. K. Bach, 1984 .

Leukotriene-C4 enhances mucus production from submucosal glands in canine trachea in vivo.

J. Nadel, M. K. Bach, A. Chow, 1983, International journal of immunopharmacology.

Preparation of large numbers of highly purified normodense human eosinophils from leukapheresis.

M. K. Bach, M. Sanders, J. R. Brashler, 1990, Journal of immunological methods.

Release of leukotrienes from guinea pig lung stimulated by C5ades Arg anaphylatoxin.

M. K. Bach, C. Bloor, T. Hugli, 1982, Journal of immunology.

Generation of lipoxygenase metabolites of arachidonic acid by monolayer cultures of tracheal epithelial cells and intact tracheal segments from rabbits.

M. K. Bach, J. R. Brashler, S. Alpert, 1990, Experimental lung research.

Prospects for the inhibition of leukotriene synthesis.

M. K. Bach, 1984, Biochemical pharmacology.

Chapter 22. Immediate Hypersensitivity: Laboratory Models and Experimental Findings

M. K. Bach, 1972 .

A molecular theory to explain the mechanisms of allergic histamine release.

M. K. Bach, 1974, Journal of theoretical biology.

6,9-deepoxy-6,9,-(phenylimino)-delta 6,8-prostaglandin I1, (U-60,257), a new inhibitor of leukotriene C and D synthesis: in vitro studies.

M. K. Bach, F. Fitzpatrick, F. Sun, 1982, Prostaglandins.

The synthesis of 6,9-deepoxy-6,9-N-phenylimino-delta 6,8-prostaglandin I1. A novel inhibitor of leukotriene C and D synthesis.

M. K. Bach, M. Wasserman, A. Harrison, 1982, Prostaglandins.

IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS

K. Austen, M. K. Bach, K. Bloch, 1971, The Journal of experimental medicine.

Biochemical and genetic studies of a mutant strain of mouse leukemia L1210 resistant to 1-beta-D-arabinofuranosylcytosine (Cytarabine).

M. K. Bach, 1969, Cancer research.

Mediators of anaphylaxis and inflammation.

M. K. Bach, 1982, Annual review of microbiology.

On the nature of the presumed receptor for IgE on mast cells. I. The effect of sialidase and phospholipase C treatment on the capacity of rat peritoneal cells to participate in IgE-mediated, antigen-induced histamine release in vitro.

M. K. Bach, J. R. Brashler, 1973, Journal of immunology.

Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells.

S. Galli, M. K. Bach, J. R. Brashler, 1987, Biochemical pharmacology.

Immediate hypersensitivity : modern concepts and developments

M. K. Bach, 1978 .

In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis.

M. K. Bach, F. Fitzpatrick, F. Sun, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

New Approaches to the Therapy of Allergic Diseases

M. K. Bach, H. G. Johnson, G. J. White, 1981 .

Two rat mononuclear cell-derived slow reacting substances: kinetic evidence that the peripheral airways-selective spasmogen is derived from a nonselectively acting precursor.

J. Drazen, M. K. Bach, M. Johnson, 1980, Immunopharmacology.

A family of calcium ionophore-induced slow reacting substances produced by rat mononuclear cells: enhancement of production with different mercaptans results in formation of different products.

M. K. Bach, J. R. Brashler, 1979, International journal of immunopharmacology.

Prevention of calcium ionophore-induced release of histamine in rat mast cells by disodium cromoglycate.

M. K. Bach, H. G. Johnson, 1975, Journal of immunology.

Solubilization and initial biochemical characterization of an IgE-destroying enzyme on rat peritoneal mast cells.

M. K. Bach, M. Johnson, K. Ishizaka, 1982, Molecular immunology.

Armed human monocytes challenged with a sensitizing cancer extract release substances pharmacologically similar to leukotrienes

M. K. Bach, D. Thomson, K. Phelan, 1982, International journal of cancer.

Studies with Inhibitors of Leukotriene Biosynthesis with Special Reference to Piriprost (U-60,257)

M. K. Bach, 1985 .

M. K. Bach, M. Sanders, T. Ishizaka, 1990, International archives of allergy and applied immunology.

On the nature of the presumed receptor for IgE on mast cells. V. Enhanced binding of 125I-labeled IgE to cell-free particulate fractions in the presence of protease inhibitors.

M. K. Bach, K. Ishizaka, T. Ishizaka, 1973, International archives of allergy and applied immunology.

Hydrazine and biological nitrogen fixation.

M. K. Bach, 1957, Biochimica et biophysica acta.

Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: a novel, particulate glutathione S-transferase.

M. K. Bach, D. R. Morton, J. R. Brashler, 1984, Archives of biochemistry and biophysics.

A Sugar‐Containing Basal Medium for Vitamin B12‐Assay with Euglena; Application to Body Fluids*

M. K. Bach, S. Hutner, G. T. Ross, 1956 .

Inhibition of rat liver glutathione S-transferases by piriprost: kinetics of the inhibition and preliminary evidence that piriprost may be a poor alternative substrate for these enzymes.

M. K. Bach, M. Johnson, J. O'Brien, 1985, Research communications in chemical pathology and pharmacology.

1,4-Dihydronaphthoquinones, hydroindoloquinones, benzofurans, and benzothiophenes as inhibitors of 5-lipoxygenase. Synthesis and structure-activity studies.

M. K. Bach, R. Schaub, M. Holm, 1990, Journal of medicinal chemistry.

Some Studies on the Antimutagenic Action of Polyamines

M. K. Bach, H. G. Johnson, 1971 .

Metabolites of 2,4-dichlorophenoxyacetic acid from bean stems.

M. K. Bach, 1961, Plant physiology.

Mechanism of stimulation of respiration by purines: I. Inhibitor studies.

M. K. Bach, 1961, Plant physiology.

Metabolism of Carboxyl-14C-labelled 2,4-Dichlorophenoxyacetic Acid by Bean Stems: Heterogeneity of the Ethanol-soluble, Ether-insoluble Products

M. K. Bach, J. Fellig, 1961, Nature.

Correlation between inactivation of 2,4-dichlorophenoxyacetic acid & cessation of callus growth in bean stem sections.

M. K. Bach, J. Fellig, 1961, Plant physiology.

Stimulation of the Respiration of Chlorella Vulgaris by Purines and Purine Analogues.

M. K. Bach, J. Fellig, 1960, Plant Physiology.

Apparent Reversal of Xanthine Oxidase Action in Chlorella vulgaris starved of Nitrogen

M. K. Bach, 1961, Nature.

Ubiquity of stimulation of endogenous respiration by purines & purine analogs.

M. K. Bach, J. Fellig, 1961, Plant physiology.

Isolation of subpopulations of lymphocytic cells by the use of isotonically balanced solutions of Ficoll. I. Development of methods and demonstration of the existence of a large but finite number of subpopulations.

M. K. Bach, J. R. Brashler, 1970, Experimental Cell Research.

Subpopulations within "short-lived" and "long-lived" lymphocytes resolved by isopycnic sedimentation in Ficoll solutions coupled with a double radioisotopic labeling technique.

M. K. Bach, J. R. Brashler, 1970, Experimental cell research.

Uptake and subcellular localization of tritiated spermine in Escherichia coli.

M. K. Bach, H. G. Johnson, 1968, Archives of biochemistry and biophysics.

The isolation and characterization of a novel microsome fraction from washed and detergent-treated nuclei of HeLa cells by the use of solutions containing deoxyribonucleic acid.

M. K. Bach, H. G. Johnson, 1967, Biochemistry.

Inhibition of IgE and compound 48/80-induced histamine release by lectins.

M. K. Bach, J. R. Brashler, 1975, Immunology.

Biochemical and Genetic Studies of a Mutant Strain of Mouse Leukemia Resistant to 1..p-D-Arabinofuranosylcytosine (Cytarabine)

M. K. Bach, 2006 .

Apparent antimutagenic activity of quinacrine hydrochloride in Detroit-98 human sternal marrow cells grown in culture.

M. K. Bach, H. G. Johnson, 1969, Cancer research.

BIOCHEMICAL STUDIES ON THE ANTIVIRAL ACTIVITIES OF THE ISATIN‐β‐THIOSEMICARBAZONES *

M. K. Bach, W. E. Magee, M. K. Bach, 1965, Annals of the New York Academy of Sciences.

The quantitative determination of spermine with platinic iodide.

M. K. Bach, 1966, Analytical biochemistry.

Biochemical Effects of Isatin β-Thiosemicarbazone on Development of Vaccinia Virus

M. K. Bach, W. E. Magee, 1962, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Reduction in the frequency of mutation to resistance to cytarabine in L1210 murine leukemic cells by treatment with quinacrine hydrochloride.

M. K. Bach, 1969, Cancer research.

Acyl cartines are potent inhibitors of mediator release

M. K. Bach, H. G. Johnson, 1980 .

IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS

K. Austen, M. K. Bach, K. Bloch, 1971, The Journal of experimental medicine.

Activity of mouse reaginic antibodies in the rat: passive cutaneous anaphylaxis and in vitro passive histamine release.

M. K. Bach, J. R. Brashler, 1973, Immunological communications.

The antimutagenic action of polyamines: suppression of the mutagenic action of an E. coli mutator gene and of 2-aminopurine.

M. K. Bach, H. G. Johnson, 1966, Proceedings of the National Academy of Sciences of the United States of America.

Mass Culture of Euglena gracilis

M. K. Bach, 1960 .

THE INHIBITION OF DEOXYRIBONUCLEOTIDYL TRANSFERASE, DNAASE AND RNAASE BY SODIUM POLY ETHENESULFONIC ACID. EFFECT OF THE MOLECULAR WEIGHT OF THE INHIBITOR.

M. K. Bach, 1964, Biochimica et Biophysica Acta.

Translocation of Photosynthetic Products to Soybean Nodules and Their Role in Nitrogen Fixation.

M. K. Bach, R. Burris, W. E. Magee, 1958, Plant physiology.

1,4-Dihydronaphthoquinones as water-soluble inhibitors of 5-lipoxygenase.

M. K. Bach, R. Schaub, M. Holm, 1990, Prostaglandins, leukotrienes, and essential fatty acids.

Activation of human eosinophils by platelet-derived growth factor.

M. K. Bach, M. Sanders, M. Bienkowski, 1992, International archives of allergy and immunology.

Platelet-derived growth factor can activate purified primate, phorbol myristate acetate-primed eosinophils.

M. K. Bach, M. Sanders, H. G. Johnson, 1991, International archives of allergy and applied immunology.

Lipid mediators of hypersensitivity.

M. K. Bach, 1988, Progress in allergy.

Formation of leukotrienes C and D and Pharmacologic modulation of their synthesis.

M. Kaliner, M. K. Bach, T. Hugli, 1982, Advances in prostaglandin, thromboxane, and leukotriene research.

A comparison of the leukotriene synthesizing ability of subfractions of rat liver glutathione S-transferases.

M. K. Bach, J. R. Brashler, 1985, Prostaglandins Leukotrienes and Medicine.

In vivo and in vitro production of a slow reacting substance in the rat upon treatment with calcium ionophores.

M. K. Bach, J. R. Brashler, 1974, Journal of immunology.

Stimulated production of slow reacting substances by mercaptans from ionophore A 23187-induced mononuclear cells: mercaptan structure-activity studies.

M. K. Bach, J. R. Brashler, 1978, Life sciences.

Polysomes on a Nuclear Membrane Fraction as Intermediates in the Transfer of Ribonucleic Acid from the Nucleus to the Cytoplasm

M. K. Bach, H. G. Johnson, 1966, Nature.

The effect of enzyme digestions on the activity of eosinophil chemotactic factor of anaphylaxis (EFC-A).

A. Kay, M. K. Bach, D. G. Jones, 1975, Immunology.

Isolation of hapten-specific antibodies from reagin-rich rat sera and their use for the preparation of rat peritoneal cells for antigen-mediated histamine release.

M. K. Bach, D. Stechschulte, J. R. Brashler, 1973, Immunochemistry.

AND PURINE ANALOGUJES

M. K. Bach, J. Fellig, Carbide Chemicals, 2016 .

IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS

K. Austen, M. K. Bach, K. Bloch, 1971, The Journal of experimental medicine.

On the nature of the presumed receptor for IgE on mast cells. II. Demonstration of the specific binding of IgE to cell-free particulate preparations from rat peritoneal mast cells.

M. K. Bach, J. R. Brashler, 1973, Journal of immunology.