B. O'connor

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Cellular profiles in asthmatic airways: a comparison of induced sputum, bronchial washings, and bronchoalveolar lavage fluid.

P. Barnes, V. Keatings, D. Evans, 1997, Thorax.

The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study.

M. Flashner, B. O'connor, N. Hanania, 2008, Pulmonary pharmacology & therapeutics.

The effects of the novel SHIP1 activator AQX‐1125 on allergen‐induced responses in mild‐to‐moderate asthma

F. Ali, P. Barnes, B. O'connor, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma

Dave Singh, B. O'connor, F. Pétavy, 2010, Respiratory research.

Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma.

K. Chung, P. Barnes, B. O'connor, 1998, American journal of respiratory and critical care medicine.

Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma.

S. Holgate, B. O'connor, H. Arshad, 2005, The Journal of allergy and clinical immunology.

CD8(+) T cell subsets and chronic obstructive pulmonary disease.

B. O'connor, D. Kemeny, L. Loh, 1999, American journal of respiratory and critical care medicine.

Hyperventilation and asymptomatic chronic asthma

W. Gardner, B. O'connor, C. Osborne, 2000, Thorax.

Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma.

K. Chung, P. Barnes, B. O'connor, 1999, American journal of respiratory and critical care medicine.

Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study.

D. Postma, A. Woodcock, R. Pauwels, 2003, American journal of respiratory and critical care medicine.

Induction of angiogenesis by airway smooth muscle from patients with asthma.

B. O'connor, C. Karner, Tak H. Lee, 2008, American journal of respiratory and critical care medicine.

Monocytes and macrophages – friend or foe?

C. Hawrylowicz, B. O'connor, C. Corrigan, 2001 .

The ideal inhaler: design and characteristics to improve outcomes.

B. O'connor, 2004, Respiratory medicine.

T cells in the lung

B. O'connor, D. Kemeny, 2000 .

The novel inhaled glucocorticoid receptor agonist GW870086X protects against adenosine-induced bronchoconstriction in asthma.

Dave Singh, P. Barnes, B. O'connor, 2015, The Journal of allergy and clinical immunology.

The 5‐lipoxygenase‐activating protein inhibitor, GSK2190915, attenuates the early and late responses to inhaled allergen in mild asthma

B. O'connor, Z. Diamant, V. Norris, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Rapid effects of extrafine beclomethasone dipropionate/formoterol fixed combination inhaler on airway inflammation and bronchoconstriction in asthma: a randomised controlled trial

P. Barnes, B. O'connor, B. Leaker, 2011, BMC pulmonary medicine.

Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients.

B. O'connor, C. Corrigan, T. Loke, 2006, The Journal of allergy and clinical immunology.

A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma.

K. Chung, P. Barnes, D. Evans, 1997, The New England journal of medicine.

A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma.

R. Pauwels, P. O'Byrne, B. O'connor, 2000, American journal of respiratory and critical care medicine.

Setipiprant, a selective CRTH2 antagonist, reduces allergen‐induced airway responses in allergic asthmatics

M. Silkey, B. O'connor, B. Leaker, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Zileuton added to low-dose inhaled beclomethasone for the treatment of moderate to severe persistent asthma.

C. Cairns, L. Boulet, B. O'connor, 2007, Respiratory medicine.

Hydrofluoroalkane-134a beclomethasone dipropionate extrafine aerosol provides equivalent asthma control to chlorofluorocarbon beclomethasone dipropionate at approximately half the total daily dose.

B. O'connor, P. Stampone, R. Davies, 1998, Respiratory medicine.

Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract.

K. Chung, P. Barnes, D. Evans, 1996, American journal of respiratory and critical care medicine.

Allergen-induced early and late asthmatic responses are not affected by inhibition of endogenous nitric oxide.

P. Barnes, B. O'connor, D. Taylor, 1998, American journal of respiratory and critical care medicine.

Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide.

P. Barnes, D. Evans, B. O'connor, 1995, American journal of respiratory and critical care medicine.

Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5′-monophosphate in asthma

P. Barnes, B. O'connor, D. Taylor, 1998, Thorax.

Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma.

A. Woodcock, Dave Singh, Richard Graham Knowles, 2007, American journal of respiratory and critical care medicine.

Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum.

P. Barnes, V. Keatings, B. O'connor, 1997, The Journal of allergy and clinical immunology.

Contrasting effects of allergen challenge on airway responsiveness to cysteinyl leukotriene D4 and methacholine in mild asthma

M. W. Jensen, M. D’Amato, B. O'connor, 2002, Thorax.

Expression and Cellular Provenance of Thymic Stromal Lymphopoietin and Chemokines in Patients with Severe Asthma and Chronic Obstructive Pulmonary Disease1

B. O'connor, C. Corrigan, Tak H. Lee, 2008, The Journal of Immunology.

Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.

P. Barnes, D. Evans, B. O'connor, 1996, Thorax.

Effects of a potent platelet-activating factor antagonist, SR27417A, on allergen-induced asthmatic responses.

P. Barnes, D. Evans, B. O'connor, 1997, American journal of respiratory and critical care medicine.

Priming of circulating human eosinophils following late response to allergen challenge.

M. Lindsay, P. Barnes, D. Evans, 1996, The European respiratory journal.

Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.

K. Chung, P. Barnes, B. O'connor, 1994, American journal of respiratory and critical care medicine.

Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease.

B. O'connor, C. Corrigan, Tak H. Lee, 2005, Journal of immunology.

Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects.

K. Chung, P. Barnes, B. O'connor, 1991, The American review of respiratory disease.

Effect of an inhaled histamine H3-receptor agonist on airway responses to sodium metabisulphite in asthma.

P. Barnes, B. O'connor, J. Lecomte, 1993, British journal of clinical pharmacology.

Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease.

P. Barnes, M. Belvisi, J. Mak, 1995, Life sciences.

Extracellular matrix regulates enhanced eotaxin expression in asthmatic airway smooth muscle cells.

A. Greenough, B. O'connor, J. Burgess, 2006, American journal of respiratory and critical care medicine.

Tolerance to the Nonbronchodilator Effects of Inhaled β2-Agonists in Asthma

P. Barnes, B. O'connor, S. Aikman, 1992 .

Selective airway responsiveness in asthma.

B. O'connor, J. Costello, J. Morley, 1999, Trends in pharmacological sciences.

Greater effect of inhaled budesonide on adenosine 5'-monophosphate-induced than on sodium-metabisulfite-induced bronchoconstriction in asthma.

P. Barnes, B. O'connor, R. Fuller, 1992, The American review of respiratory disease.

Prolonged effect of tiotropium bromide on methacholine-induced bronchoconstriction in asthma.

P. Barnes, B. O'connor, L. Towse, 1996, American journal of respiratory and critical care medicine.

271 The comparative effect of Zileuton, a 5-lipoxygenase inhibitori, plus low dose inhaled beclomethasone vs higher dose beclomethasone for asthma

L. Dubé, B. O'connor, L. Swanson, 1996 .

Effect of acetazolamide and amiloride against sodium metabisulphite-induced bronchoconstriction in mild asthma.

K. Chung, P. Barnes, B. O'connor, 1994, Thorax.

Sputum induction in corticosteroid-dependant asthmatics: risks and airway cellular profile.

M. D’Amato, B. O'connor, N. Barnes, 2005, Asian Pacific journal of allergy and immunology.

Premenstrual asthma: still poorly understood.

B. O'connor, 1997, Thorax.

Effect of inhaled corticosteroids on peripheral blood eosinophil counts and density profiles in asthma.

K. Chung, P. Barnes, B. O'connor, 1993, The Journal of allergy and clinical immunology.

Expression of prostaglandin E(2) receptor subtypes on cells in sputum from patients with asthma and controls: effect of allergen inhalational challenge.

B. O'connor, C. Corrigan, Tak H. Lee, 2004, The Journal of allergy and clinical immunology.

Dose-ranging study of mometasone furoate dry powder inhaler in the treatment of moderate persistent asthma using fluticasone propionate as an active comparator.

T. Haahtela, B. O'connor, B. Lutsky, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Albuterol does not antagonize the inhibitory effect of dexamethasone on monocyte cytokine release.

I. Adcock, P. Barnes, B. O'connor, 1998, American journal of respiratory and critical care medicine.

Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma.

M. W. Jensen, P. Barnes, B. O'connor, 1997, American journal of respiratory and critical care medicine.

Nonbronchodilator effects of inhaled beta 2 agonists. Greater protection against adenosine monophosphate- than methacholine-induced bronchoconstriction in asthma.

P. Barnes, B. O'connor, R. Fuller, 1994, American journal of respiratory and critical care medicine.

Inhibition of sodium metabisulphite induced bronchoconstriction by frusemide in asthma: role of cyclooxygenase products.

K. Chung, P. Barnes, B. O'connor, 1994, Thorax.

A novel technique to explore the functions of bronchial mucosal T cells in chronic obstructive pulmonary disease: application to cytotoxicity and cytokine immunoreactivity

C. Hawrylowicz, B. O'connor, D. Kemeny, 2010, Clinical and experimental immunology.

A dose-dependent effect of the novel inhaled corticosteroid ciclesonide on airway responsiveness to adenosine-5'-monophosphate in asthmatic patients.

M. W. Jensen, P. Barnes, B. O'connor, 1999, American journal of respiratory and critical care medicine.

Platelets are essential for leukocyte recruitment in allergic inflammation.

B. O'connor, C. Page, D. Spina, 2003, The Journal of allergy and clinical immunology.

role of cyclooxygenase products . bronchoconstriction by frusemide in asthma : Inhibition of sodium metabisulphite induced

K. Chung, P. Barnes, B. O'connor, 2004 .

Effect of neutral endopeptidase inhibitor on airway function and bronchial responsiveness in asthmatic subjects

K. Chung, P. Barnes, B. O'connor, 2004, European Journal of Clinical Pharmacology.

Protective effect of loop diuretics, piretanide and frusemide, against sodium metabisulphite-induced bronchoconstriction in asthma.

K. Chung, P. Barnes, B. O'connor, 1992, The European respiratory journal.

Effect of allergen challenge on airway responsiveness to histamine and sodium metabisulphite in mild asthma.

D. Evans, B. O'connor, L. J. Coulby, 1996, Thorax.

Expression of RANTES mRNA and protein in airways of patients with mild asthma.

K. Chung, P. Barnes, B. O'connor, 1996, American journal of respiratory and critical care medicine.

Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma.

D. Yates, K. Chung, P. Barnes, 1995, American journal of respiratory and critical care medicine.

Use of a fixed combination beta 2-agonist and steroid dry powder inhaler in asthma.

P. Barnes, B. O'connor, 1995, American journal of respiratory and critical care medicine.

M. W. Jensen, B. O'connor, D. Spina, 2002, European Respiratory Journal.

Advances in the understanding and future therapy of COPD

S. Rennard, L. Fabbri, B. O'connor, 2002 .

Airway hyperresponsiveness: relation to asthma and inflammation?

B. O'connor, D. Rogers, 1993, Thorax.

Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma.

M. W. Jensen, B. O'connor, A. Wright, 2002, The Journal of allergy and clinical immunology.

Inhaled endotoxin in healthy human subjects: a dose-related study on systemic effects and peripheral CD4+ and CD8+ T cells.

B. O'connor, D. Kemeny, L. Loh, 2006, Respiratory medicine.

Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects

B. O'connor, C. Page, D. Spina, 2008, European Respiratory Journal.

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response

K. Chung, P. Sterk, R. Djukanović, 2000, The Lancet.

Circulating autoantibodies to recombinant lipocortin-1 in asthma.

K. Chung, P. Barnes, R. Flower, 1991, Respiratory medicine.

Heparin and structurally related polymers attenuate eotaxin‐1 (CCL11) release from human airway smooth muscle

B. O'connor, C. Karner, C. Page, 2008, British journal of pharmacology.

A biochemical and functional assessment of monocyte phosphodiesterase activity in healthy and asthmatic subjects.

B. O'connor, C. Page, D. Spina, 2000, Pulmonary pharmacology & therapeutics.

Bronchoprotection with formoterol via dry powder and metered-dose inhalers in patients with asthma.

A. Morice, B. Lipworth, B. O'connor, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Proangiogenic activity in bronchoalveolar lavage fluid from patients with asthma.

B. O'connor, Tak H. Lee, G. Clarke, 2007, American journal of respiratory and critical care medicine.

Pro-Angiogenic Activity is Increased in Bronchoalveolar Lavage Fluid (BALf) from Asthmatics

B. O'connor, G. Clarke, S. Hirst, 2006 .

Elevated levels of exhaled nitric oxide in bronchiectasis.

D M Hansell, D. Hansell, P. Barnes, 1995, American journal of respiratory and critical care medicine.

Pharmacokinetic and pharmacodynamic profile following oral administration of the phosphodiesterase (PDE)4 inhibitor V11294A in healthy volunteers.

B. O'connor, C. Page, D. Spina, 2002, British journal of clinical pharmacology.

The changes in airway inflammatory cells following inhalation of lipopolysaccharide (LPS)

M. W. Jensen, B. O'connor, D. Kemeny, 2002 .

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

Sun Ying, Charlotta Karner, C. G. McVicker, 2009, Proceedings of the National Academy of Sciences.

Cytokine mRNA profiles of normal and asthmatic peripheral blood cells and endobronchial biopsies.

I. Adcock, K. Chung, P. Barnes, 1996, Biochemical Society transactions.

Thymic Stromal Lymphopoietin Expression Is Increased in Asthmatic Airways and Correlates with Expression of Th2-Attracting Chemokines and Disease Severity1

D. Robinson, B. O'connor, C. Corrigan, 2005, The Journal of Immunology.

Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma.

Stephen R Durham, S. Durham, B. O'connor, 2007, The Journal of allergy and clinical immunology.

Transcription of Ig Germline Genes in Single Human B Cells and the Role of Cytokines in Isotype Determination1

G. Felsenfeld, B. O'connor, H. Gould, 2004, The Journal of Immunology.

Superiority of “triple” therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD

B. O'connor, A. Cahn, D. Singh, 2008, Thorax.

Isotype Determination Human B Cells and the Role of Cytokines in Transcription of Ig Germline Genes in Single

B. O'connor, H. Gould, D. Fear, 2013 .

A role for mitogen kinase kinase 3 in pulmonary inflammation validated from a proteomic approach.

B. O'connor, M. Marber, C. Page, 2014, Pulmonary pharmacology & therapeutics.

Efficacy and safety of ciclesonide in patients with severe asthma: a 12-week, double-blind, randomized, parallel-group study with long-term (1-year) follow-up

B. O'connor, J. Ayres, D. Cheung, 2010, Expert opinion on pharmacotherapy.

Effects of montelukast compared to double dose budesonide on airway inflammation and asthma control.

I. Pavord, F. Hargreave, P. Corris, 2007, Respiratory medicine.

Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma.

K. Chung, P. Barnes, B. O'connor, 1995, American journal of respiratory and critical care medicine.

Cold Air and Exercise Challenge—Influence of Minute Ventilation

A. Greenough, K. Sylvester, G. Rafferty, 2007, The Journal of asthma : official journal of the Association for the Care of Asthma.

Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma.

P. Barnes, B. O'connor, S. Aikman, 1992, The New England journal of medicine.

Phosphodiesterase (PDE) 7 in inflammatory cells from patients with asthma and COPD.

M. Pruniaux, C. Bertrand, B. O'connor, 2007, Pulmonary pharmacology & therapeutics.

Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects

B. O'connor, J. Allen, C. Page, 2001, British journal of pharmacology.

Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response

Stephen T Holgate, S. Holgate, P. Barnes, 2000, The Lancet.

Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography

T. Jones, C. Rhodes, B. O'connor, 1996, The Lancet.

Some structural determinants of the antiproliferative effect of heparin‐like molecules on human airway smooth muscle

B. O'connor, C. Page, S. Hirst, 2005, British journal of pharmacology.

Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways.

N. Pedemonte, B. O'connor, L. Bini, 2005, American journal of respiratory and critical care medicine.

Expression and activation of protein kinase C-ζ in eosinophils after allergen challenge.

M. Lindsay, P. Barnes, B. Webb, 1999, American journal of physiology. Lung cellular and molecular physiology.

Expression and activation of protein kinase C-zeta in eosinophils after allergen challenge.

M. Lindsay, P. Barnes, B. Webb, 1999, The American journal of physiology.

Lack of neutrophil degranulation in low-dose endotoxin inhalation based on a novel intracellular assay.

W. Lo, B. O'connor, L. Loh, 2006, Asian Pacific journal of allergy and immunology.

Comparison of incremental and bolus dose inhaled allergen challenge in asthmatic patients

B. O'connor, Taylor, Harris, 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.

P. Barnes, D. Evans, B. O'connor, 1996, Thorax.

Airway Structure in Asthma: A Role for Confocal Microscopy?

P. Rigby, B. O'connor, C. Page, 1998 .