S. Clarke

发表

Cloning, expression, and fatty acid regulation of the human delta-5 desaturase.

H. P. Cho, M. Nakamura, S. Clarke, 1999, The Journal of biological chemistry.

Cloning, Expression, and Nutritional Regulation of the Mammalian Δ-6 Desaturase*

Manabu T. Nakamura, S. Clarke, Hyekyung P. Cho, 1999, The Journal of Biological Chemistry.

Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes.

O. MacDougald, S. Clarke, D. Jump, 1993, Proceedings of the National Academy of Sciences of the United States of America.

A novel 3 T 3L 1 preadipocyte variant that expresses PPAR g 2 and RXR a but does not undergo differentiation

S. Clarke, R. Baillie, X. Sha, 1998 .

Modification of fatty acid composition of membrane phospholipid in hepatocyte monolayer with n-3, n-6 and n-9 fatty acids and its relationship to triacylglycerol production.

S. Phinney, S. Clarke, R. Strum-Odin, 1987, Biochimica et biophysica acta.

Influence of dietary fatty acids on liver and adipose tissue lipogenesis and on liver metabolites in meal-fed rats.

G. Leveille, S. Clarke, D. Romsos, 1977, The Journal of nutrition.

Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats.

N. Ruderman, A. Saha, S. Clarke, 2005, Biochemical and biophysical research communications.

Omega-3 polyunsaturated fatty acid regulation of gene expression.

S. Clarke, C. Nelson, P. T. Price, 2000, Current opinion in lipidology.

Cellular lipid binding proteins: expression, function, and nutritional regulation 1

M. K. Armstrong, S. Clarke, M. K. Armstrong, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c.

S. Clarke, T. Gettys, T. Dreesen, 2007, The Biochemical journal.

Metabolism and functions of highly unsaturated fatty acids: An update

Manabu T. Nakamura, S. Clarke, Hyekyung P. Cho, 2001, Lipids.

Dietary fat, genes, and human health.

S. Clarke, D. Jump, A. Thelen, 1997, Advances in experimental medicine and biology.

Dietary polyunsaturated fatty acids interfere with the insulin/glucose activation of L-type pyruvate kinase gene transcription.

H. Towle, S. Clarke, D. Jump, 1994, Molecular endocrinology.

Fatty Acid Regulation of Gene Expression

D. Gašperíková, S. Clarke, A. Lapillonne, 2002 .

The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors

S. Clarke, 2004, Current opinion in lipidology.

Coordinate regulation of glycolytic and lipogenic gene expression by polyunsaturated fatty acids.

S. Clarke, D. Jump, A. Thelen, 1994, Journal of lipid research.

Specific effects of polyunsaturated fatty acids on gene expression.

S. Clarke, R. Baillie, D. Jump, 1996, Current opinion in lipidology.

Recent Advances in Nutritional Sciences Polyunsaturated Fatty Acid Regulation of Gene Transcription : A Molecular Mechanism to Improve the Metabolic Syndrome 1 , 2

S. Clarke, 2001 .

Suppliers of Energy: Carbohydrate—Fat Interrelationships

S. Clarke, D. Romsos, 1980 .

Nutritional control of rat liver fatty acid synthase and S14 mRNA abundance.

S. Clarke, D. Jump, M. K. Armstrong, 1990, The Journal of nutrition.

Dietary polyunsaturated fatty acid regulation of gene transcription.

S. Clarke, D. Jump, 1994, Annual review of nutrition.

Differential effects of dietary methyl esters of long-chain saturated and polyunsaturated fatty acids on rat liver and adipose tissue lipogenesis.

G. Leveille, S. Clarke, D. Romsos, 1977, The Journal of nutrition.

Plausible mechanisms for effects of long-chain polyunsaturated fatty acids on growth.

S. Clarke, A. Lapillonne, W. Heird, 2003, The Journal of pediatrics.

Polyunsaturated fatty acids regulate lipogenic and peroxisomal gene expression by independent mechanisms.

S. Clarke, D. Jump, Steven D. Clarke, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

Regulation of gene transcription by polyunsaturated fatty acids.

S. Clarke, D. Jump, 1993, Progress in lipid research.

Nutrient regulation of gene and protein expression.

S. Clarke, 1999, Current opinion in clinical nutrition and metabolic care.

Fatty Acid Regulation of Gene Expression Its Role in Fuel Partitioning and Insulin Resistance a

Manabu T. Nakamura, S. Clarke, D. Jump, 1997, Annals of the New York Academy of Sciences.

Polyunsaturated fatty acid regulation of hepatic gene transcription

S. Clarke, D. Jump, 2007, Lipids.

Hepatocyte nuclear factor-4α contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase

Manabu T. Nakamura, S. Clarke, T. Gettys, 2006 .

Fatty Acid Structure and Synthesis

Manabu T. Nakamura, S. Clarke, 2013 .

Fatty Acid Regulation of Gene Expression : A Genomic Mechanism to Improve the Metabolic Syndrome

D. Gašperíková, S. Clarke, A. Lapillonne, 2006 .

Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription.

S. Clarke, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Coordinate induction of peroxisomal acyl-CoA oxidase and UCP-3 by dietary fish oil: a mechanism for decreased body fat deposition.

M. Nakamura, S. Clarke, R. Baillie, 1999, Prostaglandins, leukotrienes, and essential fatty acids.

Effect of in vivo somatotropin treatment of growing pigs on adipose tissue lipogenesis.

D. Bauman, S. Clarke, F. Dunshea, 1993, Journal of animal science.

Polyunsaturated fatty acids and gene expression

S. Clarke, A. Lapillonne, W. Heird, 2004, Current opinion in clinical nutrition and metabolic care.

Acute control of fatty acid synthesis by cyclic AMP in the chick liver cell: possible site of inhibition of citrate formation.

M. Lane, S. Clarke, P. Watkins, 1979, Journal of lipid research.

Nutrient-Gene Interactions Dietary Polyunsaturated Fats Regulate Rat Liver Sterol Regulatory Element Binding Proteins-1 and-2 in Three Distinct Stages and by Different Mechanisms 1

Jung H. Y. Park, S. Clarke, J. Xu, 2002 .

Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors 1-4

S. Clarke, R. Baillie, X. Sha, 1999 .

Effects of fatty acids on hepatic gene expression.

S. Clarke, D. Jump, A. Thelen, 1995, Prostaglandins, leukotrienes, and essential fatty acids.

Copper deficiency induces hepatic fatty acid synthase gene transcription in rats by increasing the nuclear content of mature sterol regulatory element binding protein 1.

S. Clarke, R. Baillie, J. H. Lee, 2000, The Journal of nutrition.

NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription.

Manabu T. Nakamura, T. Osborne, S. Clarke, 2002, Biochemical and biophysical research communications.

Suppression of renal γ-glutamylcysteine synthetase expression in dietary copper deficiency

S. Clarke, Sangbae Kim, K. Allen, 1996 .

Adipocyte fatty acid-binding protein: regulation of gene expression in vivo and in vitro by an insulin-sensitizing agent.

S. Clarke, P. Harris, R. Kletzien, 1992, Molecular pharmacology.

Porcine fatty acid synthase: cloning of a complementary DNA, tissue distribution of its mRNA and suppression of expression by somatotropin and dietary protein.

S. Clarke, A. M. Mildner, 1991, The Journal of nutrition.

Identification of a novel enhancer sequence in the distal promoter of the rat fatty acid synthase gene.

D. Gašperíková, M. Nakamura, S. Clarke, 1999, Biochemical and biophysical research communications.

Fatty acid regulation of gene expression: a genomic explanation for the benefits of the mediterranean diet.

D. Gašperíková, S. Clarke, A. Lapillonne, 2002, Annals of the New York Academy of Sciences.

Polyunsaturated fatty acid inhibition of fatty acid synthase transcription is independent of PPAR activation.

S. Clarke, D. Jump, S. Abraham, 1998, Zeitschrift fur Ernahrungswissenschaft.

Polyunsaturated fatty acid regulation of hepatic gene transcription.

S. Clarke, D. Jump, Steven D. Clarke, 1996, The Journal of nutrition.

Suppression of rat hepatic fatty acid synthase and S14 gene transcription by dietary polyunsaturated fat.

S. Clarke, W. L. Blake, 1990, The Journal of nutrition.

Coordinate suppression of liver acetyl-CoA carboxylase and fatty acid synthetase by polyunsaturated fat.

S. Clarke, M. Wilson, M. Toussant, 1981, The Journal of nutrition.

The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile.

S. Clarke, H. Mcardle, A. Finch, 2005, Reproduction.

Polyunsaturated Fatty Acids Suppress Hepatic Sterol Regulatory Element-binding Protein-1 Expression by Accelerating Transcript Decay*

Manabu T. Nakamura, Jung H. Y. Park, S. Clarke, 2001, The Journal of Biological Chemistry.

Sterol Regulatory Element Binding Protein-1 Expression Is Suppressed by Dietary Polyunsaturated Fatty Acids

Manabu T. Nakamura, S. Clarke, Hyekyung P. Cho, 1999, The Journal of Biological Chemistry.

Polyunsaturated fatty acid regulation of gene transcription: a mechanism to improve energy balance and insulin resistance

S. Clarke, 2000, British Journal of Nutrition.

Polymer-protomer transition of acetyl-CoA carboxylase as a regulator of lipogenesis in rat liver.

S. Clarke, B. A. Clarke, 1982, Archives of biochemistry and biophysics.

Polymer-protomer transition of acetyl-CoA carboxylase occurs in vivo and varies with nutritional conditions.

S. Clarke, W. S. Fillers, B. A. Ashcraft, 1980, The Journal of biological chemistry.

Polyunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome.

S. Clarke, S D Clarke, 2001, The Journal of nutrition.

Induction of adipose fatty acid binding protein (a-FABP) by insulin-like growth factor-1 (IGF-1) in 3T3-L1 preadipocytes.

S. Clarke, W. L. Blake, 1990, Biochemical and biophysical research communications.

Regulation of Hepatic Δ-6 Desaturase Expression and Its Role in the Polyunsaturated Fatty Acid Inhibition of Fatty Acid Synthase Gene Expression in Mice

Manabu T. Nakamura, S. Clarke, Hyekyung P. Cho, 2000 .

Cytosolic and nuclear distribution of PPARgamma2 in differentiating 3T3-L1 preadipocytes.

S. Clarke, R. Baillie, X. Sha, 1998, Journal of lipid research.

A novel 3T3-L1 preadipocyte variant that expresses PPARγ2 and RXRα but does not undergo differentiation

S. Clarke, R. Baillie, X. Sha, 1998 .

Gene expression: nutrient control of pre‐ and posttranscriptional events 1

S. Clarke, S. Abraham, 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Limits of medium-chain and long-chain triacylglycerol utilization by neonatal piglets.

S. Clarke, J. Pettigrew, S. Chiang, 1990, Journal of animal science.

Cloning, Expression, and Fatty Acid Regulation of the Human Δ-5 Desaturase*

Manabu T. Nakamura, S. Clarke, Hyekyung P. Cho, 1999, The Journal of Biological Chemistry.

Regulation of gene expression by dietary fat.

S. Clarke, D. Jump, 1999, Annual review of nutrition.

Dietary polyunsaturated fats uniquely suppress rat liver fatty acid synthase and S14 mRNA content.

M. K. Armstrong, S. Clarke, D. Jump, 1990, The Journal of nutrition.

Time sequence of changes in hepatic fatty acid synthesis in rats meal-fed polyunsaturated fatty acids.

G. Leveille, S. Clarke, D. Romsos, 1977, The Journal of nutrition.

Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element.

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2003, Journal of lipid research.

The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids.

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2002, Biochemical and biophysical research communications.

Dietary polyunsaturated fatty acid regulation of gene transcription.

S. Clarke, D. Jump, A. Thelen, 1996, Progress in lipid research.

Role of sterol carrier protein in cholesterol metabolism.

H. Towle, S. Clarke, A. Mcmahon, 1985, Chemistry and physics of lipids.

A newly discovered member of the fatty acid desaturase gene family: a non-coding, antisense RNA gene to delta5-desaturase.

S. Clarke, T. Gettys, T. Dreesen, 2006, Prostaglandins, leukotrienes, and essential fatty acids.

Enhancement of adipocyte differentiation by an insulin-sensitizing agent.

R. Ulrich, S. Clarke, R. Kletzien, 1992, Molecular pharmacology.

Inhibition of triiodothyronine's induction of rat liver lipogenic enzymes by dietary fat.

S. Clarke, J. Hembree, 1990, The Journal of nutrition.

Polyunsaturated fatty acid suppression of fatty acid synthase ( FASN ) : evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1 c

S. Clarke, T. Gettys, T. Dreesen, 2007 .

Involvement of a Unique Carbohydrate-responsive Factor in the Glucose Regulation of Rat Liver Fatty-acid Synthase Gene Transcription*

Manabu T. Nakamura, S. Koo, H. Towle, 2001, The Journal of Biological Chemistry.

Potency of polyunsaturated and saturated fats as short-term inhibitors of hepatic lipogenesis in rats.

S. Clarke, M. Wilson, W. L. Blake, 1990, The Journal of nutrition.

Dietary polyunsaturated fats regulate rat liver sterol regulatory element binding proteins-1 and -2 in three distinct stages and by different mechanisms.

J. Xu, J. Park, S. Clarke, 2002, The Journal of nutrition.

Suppression of rat liver fatty acid synthesis by eicosa-5,8,11,14-tetraynoic acid without a reduction in lipogenic enzymes.

S. Clarke, B. A. Clarke, 1982, The Journal of nutrition.

Digestion and absorption of fish oil by neonatal piglets.

S. Clarke, J. Pettigrew, S. Chiang, 1989, Journal of NutriLife.

Regulation of hepatic delta-6 desaturase expression and its role in the polyunsaturated fatty acid inhibition of fatty acid synthase gene expression in mice.

H. P. Cho, M. Nakamura, S. Clarke, 2000, The Journal of nutrition.

Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors.

S. Clarke, R. Baillie, X. Sha, 1999, The American journal of clinical nutrition.

Somatotropin-dependent decrease in fatty acid synthase mRNA abundance in 3T3-F442A adipocytes is the result of a decrease in both gene transcription and mRNA stability.

S. Clarke, T. Etherton, J. L. Peters, 1998, The Biochemical journal.

Fatty Acid Synthesis and its Regulation

S. Clarke, Steven D. Clarke, 2004 .

Rapid changes in chick liver acetyl-CoA carboxylase indicative of phosphorylation control.

S. Clarke, 1983, Biochemical and biophysical research communications.

Fetal growth and fetal lung phospholipid content in rats fed safflower oil, menhaden oil, or hydrogenated coconut oil.

S. Phinney, S. Clarke, L. Benjamin, 1988, The American journal of clinical nutrition.

Hepatic fatty acid synthase gene transcription is induced by a dietary copper deficiency.

S. Clarke, R. Baillie, K. Allen, 1997, The American journal of physiology.

Essentiality of dietary carbohydrate for maintenance of liver lipogenesis in the chick.

S. Clarke, P. Lundin, B. Hillard, 1980, The Journal of nutrition.

Specific inhibition of hepatic fatty acid synthesis exerted by dietary linoleate and linolenate in essential fatty acid adequate rats

G. Leveille, S. Clarke, D. Romsos, 1976, Lipids.

Free fatty acid inhibition of the insulin induction of glucose-6-phosphate dehydrogenase in rat hepatocyte monolayers

S. Clarke, B. Adkins-Finke, L. M. Salati, 2006, Lipids.

Resistance of lung fatty acid synthesis to inhibition by dietary fat in the meal-fed rat.

S. Clarke, M. Wilson, T. Ibnoughazala, 1984, The Journal of nutrition.

Hepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase.

Manabu T. Nakamura, S. Clarke, T. Gettys, 2006, The Biochemical journal.

Arachidonic acid suppression of fatty acid synthase gene expression in cultured rat hepatocytes.

S. Clarke, W. L. Blake, M. K. Armstrong, 1991, Biochemical and biophysical research communications.

Studies of the effect of dietary cholesterol on hepatic protein synthesis, reduced glutathione levels and serine dehydratase activity in the rat.

G. Leveille, S. Clarke, W. Bergen, 1976, The Journal of nutrition.

Regulation of fatty acid synthase gene expression: an approach for reducing fat accumulation.

S. Clarke, 1993, Journal of animal science.

Inhibition of liver lipogenesis by dietary polyunsaturated fat in severely diabetic rats.

S. Clarke, M. Wilson, R. Hays, 1986, The Journal of nutrition.

Fatty acid inhibition of hormonal induction of acetyl-coenzyme A carboxylase in hepatocyte monolayers.

S. Clarke, L. M. Salati, 1986, Archives of biochemistry and biophysics.

Regulation of human Δ-6 desaturase gene transcription Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.M200195-JLR200

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2003, Journal of Lipid Research.

Type of dietary fat alters rat liver cell responsiveness to vasopressin

S. Clarke, W. L. Blake, 1991 .

Molecular methodologies in nutrition research.

S. Clarke, S D Clarke, S K Kim, 1998, The Journal of nutrition.

Hormonal triggering of the diurnal variation of sterol carrier protein.

S. Clarke, M. Dempsey, P. Hargis, 1986, The Journal of biological chemistry.

Thermogenesis secondary to transdermal water loss causes growth retardation in essential fatty acid-deficient rats.

L. Moldawer, G. Blackburn, S. Phinney, 1993, Metabolism: clinical and experimental.

Suppression of hepatocyte fatty acid synthesis by albumin-bound linoleate involves depolymerization of acetyl-CoA carboxylase filaments

S. Clarke, Bruce L. Hillard, 1981, Lipids.

Transcriptional regulation of fatty acid synthase gene by somatotropin in 3 T 3F 442 A adipocytes 1

S. Clarke, T. Etherton, D. Yin, 2001 .