N. Chiang

发表

Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.

M. Sanak, B. Levy, C. Clish, 2000, The European respiratory journal.

Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

A. Sher, C. Serhan, N. Chiang, 2005, The Journal of experimental medicine.

Resolvin E1 Selectively Interacts with Leukotriene B4 Receptor BLT1 and ChemR23 to Regulate Inflammation1

Charles N. Serhan, Makoto Arita, C. Serhan, 2007, The Journal of Immunology.

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

Charles N. Serhan, Thomas E. Van Dyke, C. Serhan, 2008, Nature Reviews Immunology.

Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.

C. Serhan, N. Chiang, G. Fredman, 2012, The American journal of pathology.

The Concise Guide to Pharmacology 2013/14: Overview

Adam J Pawson, Stephen P. H. Alexander, A. A. Khan, 2013, British journal of pharmacology.

Formylpeptide receptors in GtoPdb v.2021.2

Jilly F. Evans, S. Dahlén, M. Parmentier, 2021 .

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

S. Marullo, M. Perretti, C. Serhan, 2002, Nature Medicine.

Plasticity of leukocytic exudates in resolving acute inflammation is regulated by MicroRNA and proresolving mediators.

C. Serhan, N. Chiang, R. Baron, 2013, Immunity.

The role of N-glycosylation of human thromboxane A2 receptor in ligand binding.

H. Tai, N. Chiang, 1998, Archives of biochemistry and biophysics.

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions.

X. de la Rosa, C. Serhan, N. Chiang, 2019, The Journal of clinical investigation.

Resolvin E1 and Chemokine-like Receptor 1 Mediate Bone Preservation

D. Faibish, C. Serhan, N. Chiang, 2013, The Journal of Immunology.

A novel rat lipoxin A4 receptor that is conserved in structure and function

T. Takano, C. Serhan, N. Chiang, 2003, British journal of pharmacology.

Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

C. Serhan, N. Bazan, N. Chiang, 2022, Progress in lipid research.

Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

C. Serhan, N. Chiang, H. Arnardottir, 2015, Infection and Immunity.

Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

C. Serhan, N. Chiang, J. Dalli, 2014, Proceedings of the National Academy of Sciences.

Aspirin Has A Gender-Dependent Impact on Antiinflammatory 15-Epi-Lipoxin A4 Formation: A Randomized Human Trial

P. Ridker, C. Serhan, N. Chiang, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A4.

C. Serhan, N. Chiang, J. Clària, 1999, American journal of physiology. Cell physiology.

Novel anti-inflammatory--pro-resolving mediators and their receptors.

C. Serhan, N. Chiang, S. Krishnamoorthy, 2011, Current topics in medicinal chemistry.

Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation

C. Serhan, N. Chiang, K. Gronert, 2000, The Journal of experimental medicine.

Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).

C. Serhan, N. Chiang, J. Clària, 1999, The American journal of physiology.

Resolvin D1 and Aspirin-Triggered Resolvin D1 Regulate Histamine-stimulated Conjunctival Goblet Cell Secretion

C. Serhan, N. Chiang, Jianwei Jiao, 2013, Mucosal Immunology.

Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators.

R. Dana, C. Serhan, N. Chiang, 2009, Investigative ophthalmology & visual science.

Mediate Bone Preservation Resolvin E1 and Chemokine-like Receptor 1

D. Faibish, C. Serhan, N. Chiang, 2022 .

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.

M. Freeman, C. Clish, C. Serhan, 1999, The Journal of clinical investigation.

Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells 1

C. Serhan, N. Chiang, N. Petasis, 2003, The Journal of Immunology.

Resolution phase lipid mediators of inflammation: agonists of resolution.

C. Serhan, N. Chiang, Chia Nan, 2013, Current opinion in pharmacology.

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

C. Serhan, N. Chiang, Rong Yang, 2010, Proceedings of the National Academy of Sciences.

counterregulates leukocytes and platelets Resolvin E1, an EPA-derived mediator in whole blood, selectively

J. Schwab, C. Serhan, N. Chiang, 2008 .

Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets.

J. Schwab, U. V. von Andrian, C. Serhan, 2008, Blood.

Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling

C. Serhan, N. Chiang, F. Welty, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Design and synthesis of novel prostaglandin E2 ethanolamide and glycerol ester probes for the putative prostamide receptor(s).

S. Nikas, C. Serhan, N. Chiang, 2015, Tetrahedron letters.

Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents.

C. Serhan, N. Chiang, N. Petasis, 2013, Chemistry & biology.

Oxidoreductases in Lipoxin A4 Metabolic Inactivation

B. Levy, C. Clish, H. Tai, 2000, The Journal of Biological Chemistry.

Molecular circuits of resolution: formation and actions of resolvins and protectins

Charles N. Serhan, Makoto Arita, C. Serhan, 2005, The Journal of Immunology.

Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.

C. Clish, H. Tai, T. Takano, 1998, The Journal of pharmacology and experimental therapeutics.

The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo

Takao Shimizu, Charles N. Serhan, G. Enrico Rovati, 2006, Pharmacological Reviews.

Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A4 (ATL)

N. Chiang, J. Clària, E. Titos, 1999 .

Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.

C. Serhan, N. Chiang, K. Gronert, 2001, The American journal of pathology.

Infection Regulates Pro-Resolving Mediators that Lower Antibiotic Requirements

Charles N. Serhan, F. Bäckhed, C. Serhan, 2012, Nature.

Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation

X. de la Rosa, C. Serhan, N. Chiang, 2021, Proceedings of the National Academy of Sciences.

Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA.

C. Serhan, N. Chiang, T. Hansen, 2018, Chemistry.

Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent.

C. Serhan, N. Chiang, R. Colas, 2015, American journal of physiology. Lung cellular and molecular physiology.

Translational Research in Acute Lung Injury and Pulmonary Fibrosis Proresolving actions of a new resolvin D 1 analog mimetic qualifies as an immunoresolvent

C. Serhan, N. Chiang, R. Colas, 2015 .

Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.

C. Piantadosi, B. Kraft, C. Serhan, 2014, American journal of physiology. Lung cellular and molecular physiology.

Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.

C. Piantadosi, B. Kraft, C. Serhan, 2014, American journal of physiology. Lung cellular and molecular physiology.

Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits

C. Serhan, N. Chiang, Augustine M. K. Choi, 2013, The Journal of Immunology.

Formylpeptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Marc Parmentier, Charles N. Serhan, Takao Shimizu, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

Charles N. Serhan, Makoto Arita, J. Schwab, 2007, Nature.

Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair.

Mansher Singh, E. Eriksson, Xiaofeng Li, 2018, The Journal of investigative dermatology.

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

C. Serhan, B. Spur, N. Chiang, 2016, Proceedings of the National Academy of Sciences.

New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses

C. Serhan, B. Spur, N. Chiang, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions

C. Clish, C. Serhan, N. Chiang, 2001 .

Short Communication Selectivity of Recombinant Human Leukotriene D 4 , Leukotriene B 4 , and Lipoxin A 4 Receptors with Aspirin-Triggered 15-epi-LXA 4 and Regulation of Vascular and Inflammatory Responses

C. Serhan, N. Chiang, K. Gronert, 2000 .

Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.

C. Clish, T. Takano, C. Serhan, 2000, American journal of respiratory and critical care medicine.

Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2

C. Serhan, N. Chiang, A. Koh, 2014, The Journal of Immunology.

Cell-cell interaction in the transcellular biosynthesis of novel omega-3-derived lipid mediators.

C. Serhan, N. Chiang, Chia Nan, 2006, Methods in molecular biology.

Putting the brakes on neutrophils

C. Serhan, N. Chiang, 2006 .

Cutting Edge: Nociceptin Stimulates Neutrophil Chemotaxis and Recruitment: Inhibition by Aspirin-Triggered-15-Epi-Lipoxin A41

C. Serhan, N. Chiang, I. Fierro, 2001, The Journal of Immunology.

Aspirin-Triggered-15-Epi-Lipoxin A Inhibition by Neutrophil Chemotaxis and Recruitment : Cutting Edge : Nociceptin Stimulates

C. Serhan, N. Chiang, I. Fierro, 2001 .

Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions.

C. Clish, C. Serhan, N. Chiang, 2000, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection

C. Serhan, N. Chiang, J. Dalli, 2016 .

Resolvin T-series reduce neutrophil extracellular traps

D. Irimia, C. Serhan, B. Spur, 2021, Blood.

Expression of rat steroid 5α-reductase (isozyme-1) in Spodoptera Frugiperda, SF21, insect cells: Expression of rat steroid 5α-reductase

H. Tai, A. Bhattacharyya, N. Chiang, 1997, Steroids.

Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug.

C. Serhan, N. Chiang, 2004, Discovery medicine.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

Arthur Christopoulos, Christopher Southan, Stephen PH Alexander, 2017, British journal of pharmacology.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Stephen P. H. Alexander, Leigh A. Stoddart, Kalyan C. Tirupula, 2021, British journal of pharmacology.

Leukotriene receptors (version 2020.3) in the IUPHAR/BPS Guide to Pharmacology Database

Jilly F. Evans, J. Drazen, S. Dahlén, 2020 .

Leukotriene receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Jilly F. Evans, J. Drazen, S. Dahlén, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Macrophages and the Entrance of Resolution Phase Lipid Mediators

C. Serhan, N. Chiang, J. Dalli, 2014 .

Endogenous pro‐resolving and anti‐inflammatory lipid mediators: a new pharmacologic genus

C. Serhan, N. Chiang, C. Serhan, 2008, British journal of pharmacology.

Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX.

C. Serhan, N. Chiang, M. Arita, 2005, Prostaglandins, leukotrienes, and essential fatty acids.

Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics.

C. Serhan, N. Chiang, 2004, Rheumatic diseases clinics of North America.

Lipoxins and resolvins: Local mediators in endogenous anti-inflammation and resolution

C. Serhan, N. Chiang, 2004 .

Specialized pro-resolving mediator network: an update on production and actions.

C. Serhan, N. Chiang, Chia Nan, 2020, Essays in biochemistry.

Frontline Science: Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation

X. de la Rosa, C. Serhan, N. Chiang, 2018, Journal of leukocyte biology.

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration.

C. Serhan, N. Chiang, J. Dalli, 2017, Molecular aspects of medicine.

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

O. Werz, X. de la Rosa, Markus Werner, 2018, Nature Communications.

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors.

C. Serhan, N. Chiang, Chia Nan, 2017, Molecular aspects of medicine.

Novel Resolvin D2 Receptor Axis in Infectious Inflammation

X. de la Rosa, C. Serhan, N. Chiang, 2017, The Journal of Immunology.

Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation

C. Serhan, N. Chiang, R. Colas, 2016, The Journal of Immunology.

Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3

C. Serhan, B. Spur, N. Chiang, 2016, PloS one.

Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

C. Serhan, N. Chiang, N. Petasis, 2016, Scientific Reports.

This information is current as Infectious Inflammation Novel Resolvin D 2 Receptor Axis in

C. Serhan, N. Chiang, S. Libreros, 2016 .

The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide.

C. Piantadosi, D. Hess, B. Kraft, 2015, American journal of respiratory cell and molecular biology.

Identification of resolvin D2 receptor mediating resolution of infections and organ protection

C. Serhan, N. Chiang, R. Colas, 2015, The Journal of experimental medicine.

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

C. Serhan, N. Chiang, J. Dalli, 2015, Nature Medicine.

The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution.

C. Serhan, N. Chiang, J. Dalli, 2015, Seminars in immunology.

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome.

C. Serhan, N. Chiang, R. Colas, 2015, Biochimica et biophysica acta.

Proresolving Lipid Mediator Profiles in Baboon Pneumonia are Regulated by Inhaled Carbon Monoxide

C. Piantadosi, D. Hess, B. Kraft, 2015 .

Lipid mediators in the resolution of inflammation.

B. Levy, C. Serhan, N. Chiang, 2015, Cold Spring Harbor perspectives in biology.

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue.

C. Serhan, N. Chiang, M. Shinohara, 2014, American journal of physiology. Cell physiology.

Metabolomics‐Lipidomics of Eicosanoids and Docosanoids Generated by Phagocytes

C. Serhan, N. Chiang, Rong Yang, 2011, Current protocols in immunology.

Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins

C. Serhan, N. Chiang, Chia Nan, 2002, TheScientificWorldJournal.

Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.

B. Levy, C. Clish, C. Serhan, 2000, Ernst Schering Research Foundation workshop.

Lipoxin and Aspirin-Triggered 15-epi-Lipoxin Cellular Interactions Anti-Inflammatory Lipid Mediators

C. Clish, T. Takano, C. Serhan, 1999, Clinical chemistry and laboratory medicine.

Resolvin E 1 and Protectin D 1 Activate Inflammation-Resolution Programs

J. Schwab, C. Serhan, N. Chiang, 2009 .

Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial.

P. Ridker, C. Serhan, N. Chiang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA

C. Serhan, N. Chiang, G. Fredman, 2012, Scientific Reports.

Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression*

Song‐Pyo Hong, C. Serhan, N. Bazan, 2003, Journal of Biological Chemistry.

Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins1

C. Serhan, N. Chiang, M. Arita, 2005, The Journal of Immunology.

Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions.

M. Ferrer, Noel Southall, Xin Hu, 2019, Cell chemical biology.

Novel tail and head group prostamide probes.

S. Nikas, C. Serhan, N. Chiang, 2015, Bioorganic & medicinal chemistry letters.

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

L. Zon, C. Serhan, N. Chiang, 2018, Proceedings of the National Academy of Sciences.

MicroRNAs in resolution of acute inflammation: identification of novel resolvin Dl‐miRNA circuits

Sriram Krishnamoorthy, C. Serhan, N. Chiang, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

C. Clish, C. Serhan, N. Chiang, 2000, The Journal of experimental medicine.

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

O. Werz, X. de la Rosa, Markus Werner, 2018, Nature Communications.

RvE1 protects from local inflammation and osteoclastmediated bone destruction in periodontitis

B. Levy, C. Serhan, N. Chiang, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Anesthetics Impact the Resolution of Inflammation

J. Schwab, C. Serhan, N. Chiang, 2008, PloS one.

Resolvins and Cysteinyl-containing Pro-Resolving Mediators Activate Resolution of Infectious Inflammation and Tissue Regeneration.

C. Serhan, N. Chiang, Chia Nan, 2023, Prostaglandins & other lipid mediators.

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration.

X. de la Rosa, C. Serhan, B. Spur, 2018, The American journal of pathology.

Oxidoreductases in Lipoxin A4 Metabolic Inactivation. A Novel Role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in Inflammation

B. Levy, C. Clish, H. Tai, 2000 .

A cluster of immunoresolvents links coagulation to innate host defense in human blood

C. Serhan, N. Chiang, Paul C. Norris, 2017, Science Signaling.

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

X. de la Rosa, C. Serhan, N. Chiang, 2023, The Journal of clinical investigation.

New mechanism for an old drug Aspirin triggers anti-inflammatory lipid mediators with gender implications

C. Serhan, N. Chiang, Chia Nan, 2006, Comprehensive therapy.

Aspirin-triggered 15-epi-lipoxin A4 biosynthesis in rat liver cells.

C. Serhan, N. Chiang, J. Clària, 2002, Advances in experimental medicine and biology.

Leukotriene receptors in GtoPdb v.2023.1 Leukotriene receptors in GtoPdb v.2023.1

J. Drazen, S. Dahlén, C. Serhan, 2023 .

Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators.

R. Dana, C. Serhan, N. Chiang, 2009, Investigative ophthalmology & visual science.