K. Gronert

K. Gronert, Vinidhra Mani, Kyle J. Seamon, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The protective role of omega-3 in eye disease: new insights

K. Gronert, 2011 .

Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells.

K. Gronert, B. Hurley, B. McCormick, 2011, American journal of physiology. Lung cellular and molecular physiology.

I NFL A MMA T ION : OMEGA-3 FATTY ACIDS AND THEIR HEALTH / DISEASE CONNECTION

K. Gronert, A. Carughi, 2010 .

Acid-Derived Protectin D 1 Renoprotective Docosahexaenoic Ischemic Renal Injury and Formation of Pronounced Impact on Survival following Polyunsaturated Fatty Acids Have a-6 ω-3 and ω Acute Changes in Dietary

K. Gronert, Iram R. Hassan, 2009 .

Acute Changes in Dietary ω-3 and ω-6 Polyunsaturated Fatty Acids Have a Pronounced Impact on Survival following Ischemic Renal Injury and Formation of Renoprotective Docosahexaenoic Acid-Derived Protectin D11

K. Gronert, Iram R. Hassan, 2009, The Journal of Immunology.

Acid-Derived Protectin D 1 Renoprotective Docosahexaenoic Injury and Formation of Survival following Ischemic Renal Acids Have a Pronounced Impact on and { omega }-6 Polyunsaturated Fatty Acute Changes in Dietary

K. Gronert, 2009 .

Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.

C. Clish, T. Takano, C. Serhan, 1998, The Journal of clinical investigation.

Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon γ and Inhibits Tumor Necrosis Factor α–induced IL-8 Release

C. Serhan, K. Gronert, J. Madara, 1998, The Journal of experimental medicine.

Identification of a human enterocyte lipoxin a receptor that is regulated by IL-13 and IFN-γ and inhibits TNF-α-induced IL-8 release

C. Serhan, K. Gronert, J. Madara, 1999 .

Interdependence of lipoxin A4 and heme‐oxygenase in counter‐regulating inflammation during corneal wound healing

K. Gronert, F. Seta, M. Laniado-Schwartzman, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.

M. Freeman, C. Clish, C. Serhan, 1999, The Journal of clinical investigation.

Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs.

C. Serhan, K. Gronert, N. Petasis, 1998, The Journal of clinical investigation.

Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells

C. Serhan, K. Gronert, P. Devchand, 2003, The Journal of Biological Chemistry.

Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo.

C. Clish, C. Serhan, K. Gronert, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Immunoregulatory role of 15‐lipoxygenase in the pathogenesis of bacterial keratitis

K. Gronert, A. Jerome, S. Suvas, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense

C. Serhan, K. Gronert, P. Devchand, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Lipid mediator class switching during acute inflammation: signals in resolution

Charles N. Serhan, Clary B. Clish, B. Levy, 2001, Nature Immunology.

Heme oxygenase-2 is a critical determinant for execution of an acute inflammatory and reparative response.

R. Rezzani, N. Abraham, K. Gronert, 2006, The American journal of pathology.

Transcellular regulation of eicosanoid biosynthesis.

C. Clish, C. Serhan, K. Gronert, 1999, Methods in molecular biology.

The role of pro-resolving lipid mediators in ocular diseases.

K. Gronert, Jessica Wei, 2017, Molecular aspects of medicine.

Reaping the benefits of renal protective lipid autacoids

K. Gronert, Iram R. Hassan, 2007 .

Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.

C. Serhan, N. Chiang, K. Gronert, 2001, The American journal of pathology.

Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators.

Hau D. Le, K. Gronert, B. Kalish, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury

J. Schwab, K. Gronert, Isaac Francos-Quijorna, 2017, The Journal of Neuroscience.

Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions

C. Clish, C. Serhan, N. Chiang, 2001 .

Short Communication Selectivity of Recombinant Human Leukotriene D 4 , Leukotriene B 4 , and Lipoxin A 4 Receptors with Aspirin-Triggered 15-epi-LXA 4 and Regulation of Vascular and Inflammatory Responses

C. Serhan, N. Chiang, K. Gronert, 2000 .

Resolvins

C. Serhan, K. Gronert, P. Devchand, 2002, The Journal of Experimental Medicine.

Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.

C. Clish, T. Takano, C. Serhan, 2000, American journal of respiratory and critical care medicine.

Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17Sâ•’hydroxyâ•’DHA

V. Arroyo, J. Rodés, K. Gronert, 2006 .

Leukotriene and Lipoxin Biosynthesis

B. Levy, C. Clish, C. Serhan, 2020 .

Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions.

C. Clish, C. Serhan, N. Chiang, 2000, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.

C. Clish, T. Takano, C. Serhan, 1999, Advances in experimental medicine and biology.

ω-3 Tear Film Lipids Correlate With Clinical Measures of Dry Eye

A. Galor, K. Gronert, R. Levitt, 2016, Investigative ophthalmology & visual science.

Multidrug Resistance-Associated Transporter 2 Regulates Mucosal Inflammation by Facilitating the Synthesis of Hepoxilin

R. Mrsny, K. Gronert, H. Shi, 2008 .

Multidrug Resistance-Associated Transporter 2 Regulates Mucosal Inflammation by Facilitating the Synthesis of Hepoxilin A31

R. Mrsny, K. Gronert, H. Shi, 2008, The Journal of Immunology.

Facilitating the Synthesis of Hepoxilin A 2 Regulates Mucosal Inflammation by Multidrug Resistance-Associated Transporter

R. Mrsny, K. Gronert, H. Shi, 2008 .

Biosynthesis of thromboxane by snake (Elaphe obsoleta) erythrocytes and the requirement of eicosanoid production for blood clotting.

K. Gronert, C. Herman, X. Wang, 1997, Biochimica et biophysica acta.

Thrombocytes are the predominant source of endogenous sulfidopeptide leukotrienes in the American bullfrog (Rana catesbeiana).

K. Gronert, C. Herman, S. Virk, 1995, Biochimica et biophysica acta.

Endogenous sulfidopeptide leukotriene synthesis and 12-lipoxygenase activity in bullfrog (Rana catesbeiana) erythrocytes.

K. Gronert, C. Herman, S. Virk, 1995, Biochimica et biophysica acta.

Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase–Dependent Inflammation

K. Gronert, J. Leong, E. B. Ghanem, 2013, The Journal of Immunology.

Identiﬁcation of a Human Enterocyte Lipoxin A 4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon (cid:103) and Inhibits Tumor Necrosis Factor (cid:97) –induced IL-8 Release

C. Serhan, K. Gronert, J. Madara, 1998 .

Silicone hydrogel contact lenses retain and document ocular surface lipid mediator profiles

S. Joslin, K. Gronert, Arnav P Modi, 2022, Clinical & experimental optometry.

Local TNFR1 Signaling Licenses Murine Neutrophils for Increased TLR-Dependent Cytokine and Eicosanoid Production

G. Barton, K. Gronert, Roman Barbalat, 2017, The Journal of Immunology.

Transepithelial Bacterial-Induced Neutrophil Are Used To Coordinate 4 Leukotriene B and 3 Distinct Cellular Sources of Hepoxilin A

K. Gronert, C. Morisseau, L. Yonker, 2014 .

Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration

J. Bonventre, K. Gronert, L. Yonker, 2017, PLoS pathogens.

Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

J. Bonventre, K. Gronert, L. Yonker, 2017 .

Faculty Opinions recommendation of 12/15-Lipoxygenase regulates the inflammatory response to bacterial products in vivo.

Elvira L. Liclican, K. Gronert, 2009 .

Tissue distribution, elimination and metabolism of [3H]-leukotriene C4 in the American bullfrog, Rana catesbeiana.

K. Gronert, C. Herman, C. Pfeifer, 1993, Prostaglandins.

A Role for the Mouse 12/15-Lipoxygenase Pathway in Promoting Epithelial Wound Healing and Host Defense*

N. Maheshwari, K. Gronert, M. Dunn, 2005, Journal of Biological Chemistry.

Lipid autacoids in inflammation and injury responses: a matter of privilege.

K. Gronert, 2008, Molecular interventions.

Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy.

S. Sharma, K. Gronert, Qiong Qin, 2008, Prostaglandins, leukotrienes, and essential fatty acids.

Lipoxins and novel 15‐epi‐lipoxin analogs display potent anti‐inflammatory actions after oral administration

C. Serhan, K. Gronert, P. Devchand, 2004, British journal of pharmacology.

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

S. Leppla, K. Gronert, Charles R. Brown, 2012, Nature.

Resolvins

C. Serhan, K. Gronert, P. Devchand, 2002, The Journal of experimental medicine.

Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.

B. Levy, C. Clish, C. Serhan, 2000, Ernst Schering Research Foundation workshop.

Lipoxin and Aspirin-Triggered 15-epi-Lipoxin Cellular Interactions Anti-Inflammatory Lipid Mediators

C. Clish, T. Takano, C. Serhan, 1999, Clinical chemistry and laboratory medicine.

Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression*

Song‐Pyo Hong, C. Serhan, N. Bazan, 2003, Journal of Biological Chemistry.

Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury

J. Sivak, K. Gronert, I. Livne-bar, 2017, The Journal of clinical investigation.

Gender differences in re-epithelialisation time in fungal corneal ulcers

K. Gronert, J. Keenan, T. Lietman, 2011, British Journal of Ophthalmology.

Selective activation of the prostaglandin E2 circuit in chronic injury-induced pathologic angiogenesis.

Elvira L. Liclican, K. Gronert, Aaron B. Sullivan, 2010, Investigative ophthalmology & visual science.

A Molecular Defect in Intracellular Lipid Signaling in Human Neutrophils in Localized Aggressive Periodontal Tissue Damage1

B. Levy, C. Clish, J. A. Badwey, 2004, The Journal of Immunology.

PGD2 and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection

P. Sethupathy, K. Gronert, S. Smita, 2021, The Journal of experimental medicine.

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

Rachel B. Brem, R. Brem, G. Barton, 2019, bioRxiv.

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

C. Clish, C. Serhan, N. Chiang, 2000, The Journal of experimental medicine.

Distinct Cellular Sources of Hepoxilin A3 and Leukotriene B4 Are Used To Coordinate Bacterial-Induced Neutrophil Transepithelial Migration

K. Gronert, C. Morisseau, L. Yonker, 2015, The Journal of Immunology.

Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation.

C. Serhan, K. Gronert, S. Colgan, 1998, The Journal of pharmacology and experimental therapeutics.

NAIP‐NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL‐18 Release via Activation of Caspase‐1 and ‐8

I. Brodsky, K. Gronert, R. Vance, 2017, Immunity.

Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch

D. Julius, M. Rosenblum, K. Gronert, 2018, Proceedings of the National Academy of Sciences.

Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense

K. Gronert, S. Stanley, M. Knight, 2018, PLoS pathogens.

Aggressive Periodontal Tissue Damage Signaling in Human Neutrophils in Localized A Molecular Defect in Intracellular Lipid

B. Levy, J. A. Badwey, C. Serhan, 2004 .

Eicosanoid and Specialized Proresolving Mediator Regulation of Lymphoid Cells.

K. Gronert, Jessica Wei, 2019, Trends in biochemical sciences.

Molecular Circuits of Resolution in the Eye

Elvira L. Liclican, K. Gronert, 2010, TheScientificWorldJournal.

Distinct Isoforms of Phospholipase A2 Mediate the Ability of Salmonella enterica Serotype Typhimurium and Shigella flexneri To Induce the Transepithelial Migration of Neutrophils

K. Gronert, B. Hurley, B. McCormick, 2008, Infection and Immunity.

5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of ω-3 Polyunsaturated Fatty Acids

Elvira L. Liclican, Lois E. H. Smith, J. Sangiovanni, 2011, Science Translational Medicine.

Resolution, the grail for healthy ocular inflammation.

K. Gronert, 2010, Experimental eye research.

The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase

J. Mekalanos, C. Serhan, K. Gronert, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Fairweather Friends: Evidence of Lipoxin Dysregulation in Neurodegeneration.

J. Sivak, K. Gronert, Changmo Kim, 2019, Molecular nutrition & food research.

Dietary DHA amplifies LXA4 circuits in tissues and lymph node PMN and is protective in immune-driven dry eye disease

K. Gronert, Di Wu, John Su, 2018, Mucosal Immunology.

Effect of Omega-3 Fatty Acid Supplementation on Cardiovascular Risk Factors and Inflammatory Markers

Elvira L. Liclican, Smith, K. Gronert, 2014 .

Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension

K. Gronert, S. Karnam, J. G. Flanagan, 2023, bioRxiv.