N. Asakawa

发表

Direct Injection Method for Quantitation of Endogenous Leukotriene E_4 in Human Urine by Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry with a Column-switching Technique

N. Kishi, N. Mano, N. Asakawa, 2001, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Correlation of octanol-water partition coefficients with capacity factors measured by micellar electrokinetic chromatography.

Y. Ishihama, Y. Oda, N. Asakawa, 1994, Chemical & pharmaceutical bulletin.

Evaluation of Solute Hydrophobicity by Microemulsion Electrokinetic Chromatography

Y. Ishihama, Y. Oda, N. Asakawa, 1995 .

Hydrophobicity of cationic solutes measured by electrokinetic chromatography with cationic microemulsions.

Y. Ishihama, Y. Oda, N. Asakawa, 1996, Analytical chemistry.

Effective on-line extraction of drugs from plasma using a restricted-access media column in column-switching HPLC equipped with a dilution system: application to the simultaneous determination of ER-118585 and its metabolites in canine plasma.

N. Mano, N. Asakawa, Takashi Kato, 2009, Journal of pharmaceutical and biomedical analysis.

Highly Selective Molecular Recognition of Biologically Active Substances Using Liquid Phase Separation

N. Mano, N. Asakawa, J. Goto, 2003 .

Improvement of dissolution and oral absorption of ER-34122, a poorly water-soluble dual 5-lipoxygenase/cyclooxygenase inhibitor with anti-inflammatory activity by preparing solid dispersion.

N. Asakawa, I. Kushida, Masaki Ichikawa, 2002, Journal of pharmaceutical sciences.

Structural analysis of N-linked carbohydrate chains of funnel web spider (Agelenopsis aperta) venom peptide isomerase.

N. Mano, N. Asakawa, Y. Shikata, 1998, Bioscience, biotechnology, and biochemistry.

Development of a flavoprotein column for chiral separation by high-performance liquid chromatography

Y. Oda, N. Mano, N. Asakawa, 1992 .

Sensitive determination of aspirin and its metabolites in plasma by LC-UV using on-line solid-phase extraction with methylcellulose-immobilized anion-exchange restricted access media.

N. Asakawa, Takashi Kato, E. Yamamoto, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

On-line determination and resolution of verapamil enantiomers by high-performance liquid chromatography with column switching

Y. Oda, N. Asakawa, Tadashi Sato, 1991 .

Surfactants usable for electrospray ionization mass spectrometry.

Y. Ishihama, N. Asakawa, H. Katayama, 2000, Analytical biochemistry.

Simultaneous determination of thromboxane B2, prostaglandin E2 and leukotriene B4 in whole blood by liquid chromatography/mass spectrometry

Y. Oda, N. Mano, N. Asakawa, 1995 .

Methylcellulose-immobilized Reversed-phase Precolumn for Direct Analysis of Drugs in Plasma by HPLC

Y. Ishihama, N. Asakawa, E. Yamamoto, 2001, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Direct determination of E2020 enantiomers in plasma by liquid chromatography-mass spectrometry and column-switching techniques.

Y. Oda, N. Asakawa, S. Tanaka, 1995, Journal of chromatography. A.

Stable cationic capillary coating with successive multiple ionic polymer layers for capillary electrophoresis.

Y. Ishihama, N. Asakawa, H. Katayama, 1998, Analytical chemistry.

Optical resolution by electrokinetic chromatography using ovomucoid as a pseudo-stationary phase

Y. Ishihama, Y. Oda, N. Asakawa, 1994 .

Column-Switching High-Performance Liquid Chromatography for On-Line Simultaneous Determination and Resolution of Enantiomers of Verapamil and Its Metabolites in Plasma

Y. Oda, N. Asakawa, Tadashi Sato, 1991, Pharmaceutical Research.

Development of Novel Capillary Coating Based on Physical Adsorption for Capillary Electrophoresis

Y. Ishihama, N. Asakawa, H. Katayama, 1998 .

Application of partially fluorinated carboxylic acids as ion-pairing reagents in LC/ESI-MS.

Y. Ishihama, N. Asakawa, E. Yamamoto, 2014, Talanta.

Novel methylcellulose-immobilized cation-exchange precolumn for on-line enrichment of cationic drugs in plasma.

N. Mano, N. Asakawa, E. Yamamoto, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Reliable on-line sample preparation of basic compounds from plasma using a reversed phase restricted access media in column-switching LC.

N. Asakawa, Takashi Kato, I. Kushida, 2006, Journal of pharmaceutical and biomedical analysis.

Resolution of 1-Benzyl-4-[(5, 6-dimethoxy-1-indanon)-2-yl] Methylpiperidine Hydrochloride Enantiomers in Plasma by High-Performance Liquid Chromatography with Direct Injection Into Avidin-Conjugated Column

Y. Oda, N. Asakawa, Tadashi Sato, 1992 .

Avidin protein-conjugated column for direct injection analysis of drug enantiomers in plasma by high-performance liquid chromatography.

Y. Oda, N. Asakawa, Y. Yoshida, 1991, Journal of chromatography.

Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum

Fumitaka Osakada, S. Shimohama, A. Akaike, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A rapid method for pKa determination of drugs using pressure-assisted capillary electrophoresis with photodiode array detection in drug discovery.

Y. Ishihama, N. Asakawa, Masahiro Nakamura, 2002, Journal of pharmaceutical sciences.

Commercial Manufacture of Halaven®: Chemoselective Transformations En Route to Structurally Complex Macrocyclic Ketones

M. Kubota, N. Asakawa, Yongbo Hu, 2013, Synlett.

Enantiomeric separation by capillary electrophoresis with an electroosmotic flow-controlled capillary.

Y. Ishihama, N. Asakawa, H. Katayama, 2000, Journal of chromatography. A.

Stable capillary coating with successive multiple ionic polymer layers.

Y. Ishihama, N. Asakawa, H. Katayama, 1998, Analytical chemistry.

Migration order reversal of enantiomers in capillary electrophoretic separation

Y. Ishihama, N. Asakawa, H. Katayama, 1997 .

Characterization of lipophilicity scales using vectors from solvation energy descriptors.

Y. Ishihama, N. Asakawa, Yasushi Ishihama, 1999, Journal of pharmaceutical sciences.

Plasma direct injection high-performance liquid chromatographic method for simultaneously determining E3810 enantiomers and their metabolites by using flavoprotein-conjugated column.

Y. Oda, N. Mano, N. Asakawa, 1996, Journal of pharmaceutical sciences.

Studies of ovomucoid-, avidin-, conalbumin- and flavoprotein-conjugated chiral stationary phases for separation of enantiomers by high-performance liquid chromatography

Y. Oda, N. Mano, N. Asakawa, 1994 .

Resolution of 4-(4-chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4yl)-1(2H)-phthalazi none enantiomers in plasma with frit-FAB LC-MS using a conalbumin column.

Y. Oda, N. Mano, N. Asakawa, 1994, Journal of pharmaceutical and biomedical analysis.

Conalbumin-conjugated silica gel, a new chiral stationary phase for high-performance liquid chromatography.

Y. Oda, N. Mano, N. Asakawa, 1992, Journal of chromatography.

Drug‐plasma protein binding assay by electrokinetic chromatography‐frontal analysis

Y. Ishihama, N. Asakawa, T. Miwa, 2002, Electrophoresis.

Effective on-line purification for cationic compounds in rat bile using a column-switching LC technique.

N. Asakawa, I. Kushida, E. Yamamoto, 2006, Journal of pharmaceutical and biomedical analysis.

Direct, simultaneous measurement of liposome-encapsulated and released drugs in plasma by on-line SPE-SPE-HPLC.

N. Asakawa, H. Kikuchi, E. Yamamoto, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Direct analysis of drugs in plasma by column-switching liquid chromatography-mass spectrometry using a methylcellulose-immobilized reversed-phase pretreatment column.

N. Asakawa, E. Yamamoto, Shin-ichi Kawano, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Preparation and absolute configurations of optical isomers of sodium 2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole (E3810)

N. Asakawa, K. Hayashi, S. Souda, 1996 .

Development of a large-volume, membrane-based injection system for gradient elution micro-liquid chromatography.

N. Mano, N. Asakawa, K. Murata, 2006, Journal of chromatography. A.

Selective determination of potential impurities in an active pharmaceutical ingredient using HPLC-SPE-HPLC.

N. Asakawa, J. Niijima, E. Yamamoto, 2013, Journal of pharmaceutical and biomedical analysis.

Simultaneous quantitative determination method for sphingolipid metabolites by liquid chromatography/ionspray ionization tandem mass spectrometry.

Y. Oda, N. Mano, N. Asakawa, 1997, Analytical biochemistry.

[Determination of paeoniflorin in Paeony extract by high performance liquid chromatography (author's transl)].

N. Asakawa, T. Hattori, Y. Miyake, 1979, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Intelligent peptide-mapping method for recombinant human tissue-type plasminogen activator by lysyl-endopeptidase digestion

A. Koide, N. Asakawa, Y. Shikata, 1998 .

Liquid chromatography-mass spectrometry system using column-switching techniques

N. Asakawa, Tadashi Sato, H. Ohe, 1991 .

Structure-activity relationship of βagatoxin-TK, a peptide blocker of P/Q-type calcium channels

N. Asakawa, Tomohiro Watanabe, K. Nakajima, 1999 .

Role of d-ser46 in the P-type calcium channel blocker, ω-agatoxin-TK

N. Asakawa, Tomohiro Watanabe, K. Nakajima, 1997 .

Nano-Scale Monitoring of the Thermally-Induced Unfolding of Proteins Using Capillary Electrophoresis with In-Column Incubation

Y. Ishihama, Y. Oda, M. Iwakura, 1997 .

Selective retention of basic compounds by metal aquo-ion affinity chromatography.

N. Asakawa, E. Yamamoto, Y. Asakawa, 2014, Journal of separation science.

Electrophoretic mobility-assisted identification of proteins by nanoelectrospray capillary electrophoresis/mass spectrometry under methanolic conditions.

Y. Ishihama, Y. Oda, N. Asakawa, 2000, Rapid communications in mass spectrometry : RCM.

[Determination of curcumin content of turmeric by high performance liquid chromatography (author's transl)].

N. Asakawa, M. Tsuno, T. Hattori, 1981, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

The Retention of Lysozyme Chloride by Reversed Phase High Performance Liquid Chromatography

N. Asakawa, M. Tsuno, T. Hattori, 1981 .

Simplified gradient generator for micro- and nano-liquid chromatography.

Y. Ishihama, N. Mano, N. Asakawa, 2006, Journal of chromatography. A.

Investigation of Retention Behavior for Racemate Drugs on Avidin- and Modified Avidin-Column

Y. Oda, N. Mano, N. Asakawa, 1994 .

A hydrophobicity scale based on the migration index from microemulsion electrokinetic chromatography of anionic solutes

Y. Ishihama, Y. Oda, N. Asakawa, 1996 .

On-line determination and resolution of the enantiomers of ketoprofen in plasma using coupled achiral-chiral high-performance liquid chromatography.

Y. Oda, N. Asakawa, Y. Yoshida, 1992, Journal of pharmaceutical and biomedical analysis.

Suppression effects of carbonate on the interaction between stainless steel and phosphate groups of phosphate compounds in high-performance liquid chromatography and electrospray ionization mass spectrometry.

N. Asakawa, Y. Asakawa, Noriaki Tokida, 2008, Journal of chromatography. A.

Weak cation-exchange restricted-access material for on-line purification of basic drugs in plasma.

N. Asakawa, Takashi Kato, Yoshiaki Sato, 2008, Journal of chromatography. A.

On-line pretreatment using methylcellulose-immobilized cation-exchange restricted access media for direct liquid chromatography/mass spectrometric determination of basic drugs in plasma.

N. Asakawa, Shin-ichi Kawano, Takashi Hine, 2005, Rapid communications in mass spectrometry : RCM.

Investigation of Interactions Between Drug Enantiomers and Flavoprotein as a Chiral Selector by Affinity Capillary Electrophoresis

Y. Ishihama, Y. Oda, N. Mano, 1998 .

Relationship between the Association Constant and Enantioselectivity on the Flavoprotein-Conjugated Chiral Stationary Phase for High-Performance Liquid Chromatography

Y. Ishihama, Y. Oda, N. Mano, 1995 .

Comparison of Avidin and Ovomucoid as Chiral Selectors for the Resolution of Drug Enantiomers by High-Performance Liquid Chromatography

Y. Oda, N. Mano, N. Asakawa, 1993 .

Microscale determination of dissociation constants of multivalent pharmaceuticals by capillary electrophoresis.

Y. Ishihama, Y. Oda, N. Asakawa, 1994, Journal of pharmaceutical sciences.

Reduction of carry-over in column-switching HPLC/MS system with automated system washing procedure for highly sensitive direct analysis of donepezil in dog plasma.

N. Asakawa, Y. Asakawa, S. Kaneko, 2007, Journal of pharmaceutical and biomedical analysis.

Highly robust stainless steel tips as microelectrospray emitters.

Naoki Asakawa, Yoshiya Oda, Yasushi Ishihama, 2002, Rapid communications in mass spectrometry : RCM.

Development of an N-shaped cell for two-phase partitioning.

Y. Ishihama, N. Asakawa, K. Uchikawa, 2000 .

Enantioselective high-performance liquid chromatographic assay for determination of the enantiomers of a new anti-ulcer agent, E3810, in beagle dog plasma and rat plasma.

N. Mano, N. Asakawa, H. Nakata, 1995, Journal of chromatography. B, Biomedical applications.

Application of an ovomucoid-conjugated polymer column for the enantiospecific determination of chlorprenaline concentrations in plasma.

N. Asakawa, J. Haginaka, S. Sakashita, 1991, Journal of Chromatography A.

On-line Sample Preparation System Using Column-Switching HPLC for the Structure Elucidation of Compounds in Mixtures by NMR

N. Asakawa, Yumi Yokoyama, Naoya Kishi, 2000 .