A. Wardlaw

发表

Comparison of airway immunopathology of eosinophilic bronchitis and asthma

I. Pavord, S. Birring, F. Symon, 2003, Thorax.

Induced sputum inflammatory mediator concentrations in chronic cough.

I. Pavord, S. Birring, C. Brightling, 2004, American journal of respiratory and critical care medicine.

Clinical reviews in allergy and immunology

H. Ortega, H. Simon, G. Gauvreau, 2014 .

Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis

B. Hargadon, C. Brightling, J. Eastham‐Anderson, 2018, The Journal of allergy and clinical immunology.

Induced sputum eicosanoid concentrations in asthma.

I. Pavord, R. Dworski, J. Sheller, 1999, American journal of respiratory and critical care medicine.

Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood

Geoffrey L. Chupp, Andrew A. Hill, Andrew J. Wardlaw, 2011, PloS one.

Effector Cells of Allergy

H. Simon, C. Hawrylowicz, A. Wardlaw, 2006 .

Novel targeted therapies for eosinophilic disorders.

H. Ortega, H. Simon, G. Gauvreau, 2012, The Journal of allergy and clinical immunology.

Mast-cell infiltration of airway smooth muscle in asthma.

I. Pavord, F. Symon, S. Holgate, 2002, The New England journal of medicine.

Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis.

I. Pavord, C. Brightling, P. Bradding, 2007, The Journal of allergy and clinical immunology.

A comparison of the validity of different diagnostic tests in adults with asthma.

Christopher E Brightling, Andrew J Wardlaw, Ian D Pavord, 2002, Chest.

The safety and success rate of sputum induction using a low output ultrasonic nebuliser.

I. Pavord, A. Wardlaw, G. Woltmann, 1999, Respiratory medicine.

Non-eosinophilic cor ticosteroid unresponsive asthma

I. Pavord, C. Brightling, A. Wardlaw, 1999, The Lancet.

Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial

I. Pavord, B. Hargadon, C. Brightling, 2007, European Respiratory Journal.

Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma.

C. Brightling, P. Berger, P. Bradding, 2006, American journal of respiratory and critical care medicine.

Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma.

I. Pavord, F. Symon, A. Sousa, 2013, American journal of respiratory and critical care medicine.

Refining the definition of hypereosinophilic syndrome.

H. Simon, A. Wardlaw, M. Wechsler, 2010, The Journal of allergy and clinical immunology.

Efficacy and safety of mepolizumab in hypereosinophilic syndrome: Aphase III, randomized, placebo-controlled trial

S. Yancey, A. Wardlaw, M. Rothenberg, 2020 .

Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial

S. Yancey, A. Wardlaw, G. Gleich, 2020, Journal of Allergy and Clinical Immunology.

The causes of a peripheral blood eosinophilia in a secondary care setting

A. Wardlaw, S. Siddiqui, S. Shaffu, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Adiponectin: A Novel Link between Adipose Tissue and Chronic Obstructive Pulmonary Disease

J. Bousquet, J. Heinrich, J. Garcia-Aymerich, 2013 .

Fungal sensitization and its relationship to mepolizumab response in patients with severe eosinophilic asthma

F. Albers, E. Israel, P. Howarth, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma.

I. Pavord, S. Gupta, C. Brightling, 2010, The Journal of allergy and clinical immunology.

Laser-scanning cytometry

D. Rew, A. Wardlaw, G. Woltmann, 1999, The Lancet.

Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma

I. Pavord, D. Shaw, B. Hargadon, 2005, European Respiratory Journal.

Systemic Corticosteroids in Asthma

A. Wardlaw, R. Green, 2005 .

Differential expression of CCR3 and CXCR3 by human lung and bone marrow‐derived mast cells: implications for tissue mast cell migration

A. Morgan, C. Brightling, P. Berger, 2005, Journal of leukocyte biology.

Cluster analysis and clinical asthma phenotypes.

Mike Thomas, Pranab Haldar, Ian D. Pavord, 2008, American journal of respiratory and critical care medicine.

Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract.

A. Wardlaw, M. Rothenberg, D. Simon, 2010, The Journal of allergy and clinical immunology.

Refractory asthma phenotypes and the response to sputum eosinophil directed therapy

I. Pavord, A. Wardlaw, R. Green, 2006 .

Categorising the asthma phenotype: Results of a factor analysis

I. Pavord, A. Wardlaw, R. Green, 2005 .

Evidence of a role of tumor necrosis factor alpha in refractory asthma.

I. Pavord, D. Shaw, B. Hargadon, 2006, The New England journal of medicine.

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma

I. Pavord, D. Shaw, C. Brightling, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Exacerbations of severe asthma in patients treated with mepolizumab

I. Pavord, S. Yancey, B. Hargadon, 2018, European Respiratory Journal.

Airway hyperresponsiveness is dissociated from airway wall structural remodeling.

I. Pavord, A. Morgan, C. Brightling, 2008, The Journal of allergy and clinical immunology.

Asthma exacerbations and sputum eosinophil counts

I. Pavord, C. Brightling, A. Wardlaw, 2003, The Lancet.

Asthma exacerbations and sputum eosinophil counts. Authors' reply

B. Lipworth, C. Brightling, A. Wardlaw, 2003 .

Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis.

I. Pavord, A. Morgan, C. Brightling, 2004, The Journal of allergy and clinical immunology.

Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.

J. Sheikh, J. Ring, H. Simon, 2009, The Journal of allergy and clinical immunology.

The influence of age on induced sputum differential cell counts in normal subjects.

I. Pavord, S. Birring, C. Brightling, 2004, Chest.

Aspergillus fumigatus during stable state and exacerbations of COPD

I. Pavord, C. Brightling, A. Wardlaw, 2013, European Respiratory Journal.

Biological Mechanism Associated with Asthma Exacerbation Attack as Revealed By Gene Expression Patterns of Peripheral Blood Mononuclear Cells

U. Bjornsdottir, P. Thompson, S. Holgate, 2009 .

Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

I. Pavord, D. Shaw, B. Hargadon, 2007, Chest.

Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: a 12-month follow-up analysis.

I. Pavord, H. Ortega, S. Gupta, 2014, The Journal of allergy and clinical immunology.

Hypereosinophilic syndromes: A multicenter, retrospective analysis of clinical characteristics and response to therapy

J. Sheikh, H. Simon, T. Nutman, 2010 .

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment

I. Pavord, C. Brightling, R. Smallwood, 2019, Science Translational Medicine.

Development of irreversible airflow obstruction in a patient with eosinophilic bronchitis without asthma.

I. Pavord, C. Brightling, A. Wardlaw, 1999, The European respiratory journal.

Human Lung Mast Cells Adhere to Human Airway Smooth Muscle, in Part, via Tumor Suppressor in Lung Cancer-11

C. Brightling, Y. Okayama, P. Bradding, 2006, The Journal of Immunology.

A placebo controlled comparison of formoterol, montelukast or higher dose of inhaled corticosteroids in subjects with symptomatic asthma despite treatment with low dose inhaled corticosteroids

I. Pavord, B. Hargadon, C. Brightling, 2002 .

Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV1.

I. Pavord, B. Hargadon, C. Brightling, 2012 .

Routine processing procedures for isolating filamentous fungi from respiratory sputum samples may underestimate fungal prevalence

C. Brightling, A. Wardlaw, M. Bafadhel, 2011, Medical mycology.

Vascular remodelling is a feature of asthma and non-asthmatic eosinophilic bronchitis

I. Pavord, B. Hargadon, C. Brightling, 2006 .

Clinicians should be proactive in testing for asthma

I. Pavord, A. Wardlaw, 1999, BMJ.

Mast cell localization within the airway smooth muscle: relationship to airway hyperresponsiveness and other asthma phenotypes

I. Pavord, C. Brightling, P. Bradding, 2004 .

Objective quantitative analysis of eosinophils and bronchial epithelial cells in induced sputum by laser scanning cytometry

I. Pavord, F. Symon, D. Rew, 1999, Thorax.

The correlation between exhaled nitric oxide and sputum eosinophil counts in patients with airways disease

I. Pavord, D. Shaw, C. Brightling, 2007 .

Refining the definition of hypereosinophilic syndrome The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

H. Simon, A. Wardlaw, M. Wechsler, 2012 .

Rostrum Refining the definition of hypereosinophilic syndrome

H. Simon, A. Wardlaw, M. Wechsler, 2011 .

Bronchoalveolar lavage invariant natural killer T cells are not increased in asthma.

C. Guillén, C. Brightling, D. Thickett, 2007, The Journal of allergy and clinical immunology.

A case of cough, lymphocytic bronchoalveolitis and coeliac disease with improvement following a gluten free diet

I. Pavord, F. Symon, C. Brightling, 2002, Thorax.

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

I. Pavord, C. Brightling, A. Wardlaw, 2000, The Lancet.

Improvement in health status following bronchopulmonary hygiene physical therapy in patients with bronchiectasis.

I. Pavord, S. Birring, A. Wardlaw, 2008, Respiratory medicine.

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

I. Pavord, C. Brightling, A. Wardlaw, 2002, Thorax.

Lymphocytic bronchoalveolitis in idiopathic chronic cough

I. Pavord, S. Birring, F. Symon, 2002 .

Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability.

I. Pavord, C. Brightling, M. Morgan, 2001, Respiratory medicine.

S91 Aspergillus fumigatus sensitisation in patients with chronic obstructive pulmonary disease

I. Pavord, C. Brightling, A. Wardlaw, 2011, Thorax.

P174 Identifying non-adherence with asthma medication and the relationship to clinical outcomes amongst adults with difficult-to-control asthma

I. Pavord, C. Brightling, P. Bradding, 2010, Thorax.

Changes in airway wall geometry of the apical segmental bronchus in non-eosinophilic asthma

I. Pavord, C. Brightling, G. Cruse, 2006 .

Effectiveness of voriconazole in the treatment of Aspergillus fumigatus-associated asthma (EVITA3 study).

I. Pavord, B. Hargadon, C. Brightling, 2014, The Journal of allergy and clinical immunology.

Heterogeneity in refractory asthma: The use of cluster analysis to identify distinct cohorts

I. Pavord, A. Wardlaw, R. Green, 2005 .

Mepolizumab in refractory eosinophilic asthma

I. Pavord, P. Bradding, A. Wardlaw, 2010, Thorax.

Multiple inflammatory hits and the pathogenesis of severe airway disease

I. Pavord, C. Brightling, A. Wardlaw, 2006, European Respiratory Journal.

Revisiting the NIH Taskforce on the Research needs of Eosinophil‐Associated Diseases (RE‐TREAD)

H. Simon, A. Wardlaw, M. Wechsler, 2018, Journal of leukocyte biology.

Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial

S. Yancey, A. Wardlaw, G. Gleich, 2020, The Journal of allergy and clinical immunology.

Qualitative analysis of high-resolution CT scans in severe asthma.

I. Pavord, S. Gupta, C. Brightling, 2009, Chest.

Late-breaking abstract: Phase 2a randomized placebo-controlled trial of the oral prostaglandin D2 receptor (DP2/ CRTh2) antagonist QAWo39 in eosinophilic asthma

I. Pavord, C. Brightling, A. Wardlaw, 2014 .

Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis.

I. Pavord, C. Brightling, A. Wardlaw, 2000, The European respiratory journal.

The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle.

C. Brightling, A. Ammit, P. Bradding, 2005, American journal of respiratory and critical care medicine.

Inflammatory cell infiltration into proximal airway smooth muscle bundles in subjects with and without chronic obstructive pulmonary disease

I. Pavord, C. Brightling, A. Wardlaw, 2006 .

Allergic Fungal Airway Disease Is a Distinct Endotype of Difficult-to-Treat Asthma.

A. Wardlaw, 2021, The journal of allergy and clinical immunology. In practice.

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes

I. Pavord, S. Gupta, C. Brightling, 2010, Thorax.

DNA analysis of outdoor air reveals a high degree of fungal diversity, temporal variability, and genera not seen by spore morphology.

R. Free, A. Wardlaw, A. Fairs, 2012, Fungal biology.

Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma

I. Pavord, A. Morgan, D. Shaw, 2007, Thorax.

Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial

I. Pavord, B. Hargadon, C. Brightling, 2002, The Lancet.

Fungi and allergic lower respiratory tract diseases.

Andrew J Wardlaw, Anupma Dixit, H. Vijay, 2012, The Journal of allergy and clinical immunology.

Guidelines on ambient intramural airborne fungal spores.

A. Wardlaw, A. Fairs, C. Pashley, 2010, Journal of investigational allergology & clinical immunology.

Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV1

I. Pavord, B. Hargadon, C. Brightling, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Allergic fungal airways disease (AFAD): an under-recognised asthma endotype

A. Wardlaw, C. Pashley, 2021, Mycopathologia.

Allergic Fungal Airway Disease.

A. Wardlaw, K. Woolnough, C. Pashley, 2016, Journal of investigational allergology & clinical immunology.

IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma.

I. Pavord, B. Hargadon, C. Brightling, 2010, American journal of respiratory and critical care medicine.

Increased sputum and bronchial biopsy IL-13 expression in severe asthma.

I. Pavord, A. Morgan, C. Brightling, 2008, The Journal of allergy and clinical immunology.

The Chemokine CXCL16 is Highly and Constitutively Expressed by Human Bronchial Epithelial Cells

C. Guillén, A. Wardlaw, Rashmika Patel, 2009, Experimental lung research.

Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma.

C. Brightling, A. Wardlaw, J. Bankart, 2010, The Journal of allergy and clinical immunology.

Eosinophilic bronchitis is an important cause of chronic cough.

A J Wardlaw, I. Pavord, C. Brightling, 1999, American journal of respiratory and critical care medicine.

Mepolizumab and exacerbations of refractory eosinophilic asthma.

Ana Sousa, Christopher E Brightling, Peter Bradding, 2009, The New England journal of medicine.

Management of asthma in adults: current therapy and future directions

I. Pavord, C. Brightling, A. Wardlaw, 2003, Postgraduate medical journal.

The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial.

I. Pavord, D. Shaw, C. Brightling, 2007, American journal of respiratory and critical care medicine.

Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial.

I. Pavord, C. Brightling, A. Wardlaw, 2016, The Lancet. Respiratory medicine.

Phenotyping airways disease: an A to E approach

I. Pavord, V. Raj, A. Wardlaw, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study.

Surinder S Birring, Christopher E Brightling, Peter Bradding, 2002, American journal of respiratory and critical care medicine.

NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma

C. Brightling, P. Andrew, A. Wardlaw, 2016, Chest.

The relationship between clinical outcomes and medication adherence in difficult-to-control asthma

Christopher E Brightling, Peter Bradding, Andrew J Wardlaw, 2012, Thorax.

Real-time multi-marker measurement of organic compounds in human breath: towards fingerprinting breath

Andrew M Ellis, Andrew J Wardlaw, Rebecca Cordell, 2013, Journal of breath research.

Body Mass and Fat Mass in Refractory Asthma: An Observational 1 Year Follow-Up Study

I. Pavord, B. Hargadon, C. Brightling, 2010, Journal of allergy.

Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis

I. Pavord, S. Birring, F. Symon, 2003, Thorax.

Fibrocyte localization to the airway smooth muscle is a feature of asthma.

C. Brightling, P. Bradding, A. Wardlaw, 2009, The Journal of allergy and clinical immunology.

Reproducibility between counts of airborne allergenic pollen from two cities in the East Midlands, UK

A. Wardlaw, J. Corden, A. Fairs, 2009 .

IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis

Salman Siddiqui, Christopher Brightling, C. Brightling, 2009, BMC pulmonary medicine.

Association of beta‐2‐adrenoceptor polymorphisms and pulmonary function in patients with chronic obstructive pulmonary disease

A. Wheatley, S. Parker, A. Wardlaw, 2006 .

Characterization of the migration of lung and blood T cells in response CXCL12 in a three-dimensional matrix

C. Guillén, A. Wardlaw, G. Willars, 2010, Immunology.

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes

I. Pavord, S. Gupta, C. Brightling, 2010, Thorax.

Associations in asthma between quantitative computed tomography and bronchial biopsy-derived airway remodelling

A. Sousa, S. Gupta, C. Brightling, 2017, European Respiratory Journal.

Vocal cord paralysis in association with pulmonary emboli.

A. Wardlaw, K. J. Thomson, 1986, British journal of diseases of the chest.

Expression of CXCR6 and its ligand CXCL16 in the lung in health and disease

I. Pavord, A. Morgan, C. Guillén, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Eosinophils in asthma and other allergic diseases.

A J Wardlaw, G Woltmann, I. Pavord, 2000, British medical bulletin.

Mechanical stretch has contrasting effects on mediator release from bronchial epithelial cells, with a rho-kinase-dependent component to the mechanotransduction pathway.

B. Williams, A. Wardlaw, J. Norman, 2006, Respiratory medicine.

Mechanisms of eosinophil and basophil migration

F. Symon, A. Wardlaw, G. Walsh, 1994, Allergy.

Breathing exercises for asthma: a randomised controlled trial

I. Pavord, D. Price, D. Shaw, 2008, Thorax.

Multi‐dimensional phenotyping: towards a new taxonomy for airway disease

I. Pavord, A. Wardlaw, A. Wardlaw, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Sputum Inflammatory Mediators Are Increased in Aspergillus fumigatus Culture-Positive Asthmatics

C. Brightling, A. Wardlaw, L. Rapley, 2016, Allergy, asthma & immunology research.

Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease

I. Sayers, B. Beghé, A. Wardlaw, 2010, Allergy.

Isolation of Aspergillus fumigatus from sputum is associated with elevated airborne levels in homes of patients with asthma.

B. Hargadon, A. Wardlaw, A. Fairs, 2013, Indoor air.

What is severe asthma?

A. Wardlaw, A. Wardlaw, J. Blakey, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Allergie Bronchopulmonary Aspergillosis: A Review

A. Wardlaw, D. Geddes, A. Wardlaw, 1992, Journal of the Royal Society of Medicine.

New insights into the relationship between airway inflammation and asthma.

I. Pavord, A. Wardlaw, C. Brightling, 2002, Clinical science.

The A to E of airway disease

A. Wardlaw, I. Pavord, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Interleukin‐4 and ‐13 expression is co‐localized to mast cells within the airway smooth muscle in asthma

I. Pavord, F. Symon, S. Holgate, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Comparison of airway immunopathology of eosinophilic bronchitis and asthma

I. Pavord, S. Birring, F. Symon, 2003, Thorax.

Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract.

A. Wardlaw, M. Rothenberg, D. Simon, 2010, The Journal of allergy and clinical immunology.

What is severe asthma?

A. Wardlaw, J. Blakey, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Observational study of the natural history of eosinophilic bronchitis

I. Pavord, D. Shaw, B. Hargadon, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.