J. Boyce

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Cutting Edge: Interleukin 4-Dependent Mast Cell Proliferation Requires Autocrine/Intracrine Cysteinyl Leukotriene-Induced Signaling1

Yongfeng Jiang, Y. Kanaoka, Chunli Feng, 2006, The Journal of Immunology.

Eicosanoids in asthma, allergic inflammation, and host defense.

J. Boyce, 2008, Current molecular medicine.

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Fabian J Theis, D. Pe’er, A. Regev, 2020, Cell.

Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes.

J. Boyce, M. Collins, M. Rothenberg, 2004, The Journal of allergy and clinical immunology.

Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report.

Carol Byrd-Bredbenner, Jon M Hanifin, Sami L Bahna, 2010, The Journal of allergy and clinical immunology.

Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report.

B. Yawn, R. Simon, F. Simons, 2011, Journal of the American Academy of Dermatology.

Advances in mechanisms of asthma, allergy, and immunology in 2008.

D. Broide, J. Boyce, Kenji Matsumoto, 2009, The Journal of allergy and clinical immunology.

NIAID-Sponsored 2010 Guidelines for Managing Food Allergy: Applications in the Pediatric Population

A. Burks, H. Sampson, J. Boyce, 2011, Pediatrics.

Leukotriene E4–induced pulmonary inflammation is mediated by the P2Y12 receptor

S. Paruchuri, W. Xing, Yongfeng Jiang, 2009, The Journal of experimental medicine.

A trial of type 12 purinergic (P2Y12) receptor inhibition with prasugrel identifies a potentially distinct endotype of patients with aspirin‐exacerbated respiratory disease

E. Israel, J. Cui, J. Boyce, 2019, The Journal of allergy and clinical immunology.

Biology of Mast Cells and their Mediators

J. Boyce, F. Hsu, 2009 .

Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes.

N. Bhattacharyya, W. Xing, J. Boyce, 2012, Blood.

Leukotriene D4 Paradoxically Limits LTC4 Driven Platelet Activation and Lung Immunopathology.

Chunli Feng, J. Boyce, N. Barrett, 2020, The Journal of allergy and clinical immunology.

Cysteinyl Leukotriene Receptor 2 Drives Lung Immunopathology Through a Platelet and High Mobility Box 1-Dependent Mechanism

Y. Kanaoka, Chunli Feng, J. Boyce, 2019, Mucosal Immunology.

Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function.

J. Boyce, 2019, The Journal of allergy and clinical immunology.

Aspirin-exacerbated respiratory disease: Mediators and mechanisms of a clinical disease.

J. Boyce, K. Cahill, 2017, The Journal of allergy and clinical immunology.

Aspirin-Exacerbated Respiratory Disease--New Prime Suspects.

J. Boyce, T. Laidlaw, 2016, The New England journal of medicine.

Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein–coupled receptor, GPR99

K. Austen, Y. Kanaoka, J. Boyce, 2016, Proceedings of the National Academy of Sciences.

A Aspirin-Exacerbated Respiratory Disease Baseline B Aspirin Reaction

J. Boyce, T. Laidlaw, 2016 .

Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene–Driven IL-33–Mediated Mast Cell Activation Pathway

Y. Kanaoka, Chunli Feng, J. Boyce, 2015, The Journal of Immunology.

Platelets in patients with aspirin-exacerbated respiratory disease.

J. Boyce, T. Laidlaw, 2015, The Journal of allergy and clinical immunology.

Platelet-Driven Leukotriene C4–Mediated Airway Inflammation in Mice Is Aspirin-Sensitive and Depends on T Prostanoid Receptors

Chunli Feng, J. Boyce, T. Laidlaw, 2015, The Journal of Immunology.

Cysteinyl Leukotrienes and Disease

J. Boyce, L. Fanning, Laura B. Fanning, 2015 .

Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease.

Chunli Feng, J. Boyce, T. Laidlaw, 2014, The Journal of allergy and clinical immunology.

Prostaglandin D 2 : A dominant mediator of aspirin-exacerbated respiratory disease

J. Boyce, T. Laidlaw, K. Cahill, 2022 .

Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes

J. Boyce, T. Laidlaw, H. Katz, 2013, Proceedings of the National Academy of Sciences.

Cutting Edge: Leukotriene C4 Activates Mouse Platelets in Plasma Exclusively through the Type 2 Cysteinyl Leukotriene Receptor

Y. Kanaoka, Chunli Feng, J. Boyce, 2013, The Journal of Immunology.

Lipid mediators and allergic diseases.

J. Boyce, L. Fanning, Laura B. Fanning, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pathogenesis of aspirin-exacerbated respiratory disease and reactions.

J. Boyce, T. Laidlaw, 2013, Immunology and allergy clinics of North America.

Activation of group 2 innate lymphoid cells: a new role for cysteinyl leukotrienes.

J. Boyce, N. Barrett, 2013, The Journal of allergy and clinical immunology.

Cysteinyl leukotriene receptors, old and new; implications for asthma

J. Boyce, T. Laidlaw, Tanya M. Laidlaw, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.

K. Austen, B. Lam, J. Penrose, 2001 .

T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–Dependent Cysteinyl Leukotriene Production by Human Cord Blood–Derived Mast Cells

K. Austen, B. Lam, J. Penrose, 2001, The Journal of experimental medicine.

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

M. Wadsworth, T. Hughes, S. Kazer, 2017, bioRxiv.

beta(2)-Microglobulin modified with advanced glycation end products delays monocyte apoptosis.

W. Owen, G. Chertow, T. Miyata, 2001, Kidney international.

Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation

J. Boyce, 2007, Immunological reviews.

Neonatal Mast Cells and Transplacental IgE Transfer: A Mechanism of Disease Inheritance or of Passive Infant Barrier Defense?

J. Boyce, D. Dwyer, Daniel F. Dwyer, 2021, The Journal of allergy and clinical immunology.

Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway

J. Boyce, S. K. Samuchiwal, B. Balestrieri, 2017, The Journal of Biological Chemistry.

Lysophosphatidic acid accelerates the development of human mast cells.

D. Friend, K. Austen, J. Boyce, 2004, Blood.

Role of lipid mediators and control of lymphocyte responses in type 2 immunopathology

J. Boyce, S. K. Samuchiwal, Sachin K. Samuchiwal, 2018, The Journal of allergy and clinical immunology.

Cysteinyl leukotrienes: an innate system for epithelial control of airway smooth muscle proliferation?

J. Boyce, N. Barrett, 2015, American journal of respiratory and critical care medicine.

Differential Regulation of Cysteinyl Leukotriene Receptor Signaling by Protein Kinase C in Human Mast Cells

S. Paruchuri, J. Boyce, C. Thodeti, 2013, PloS one.

Leukotriene E 4 – induced pulmonary inflammation is mediated by the P 2 Y 12 receptor

S. Paruchuri, W. Xing, Yongfeng Jiang, 2009 .

Leukotriene E4 Activates Peroxisome Proliferator-activated Receptor γ and Induces Prostaglandin D2 Generation by Human Mast Cells*

J. Plutzky, S. Paruchuri, Yongfeng Jiang, 2008, Journal of Biological Chemistry.

Immune and Inflammatory Responses Cellular Distribution and Function in Cysteinyl Leukotrienes and Their Receptors:

Y. Kanaoka, J. Boyce, 2004 .

Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors.

W. Owen, D. Friend, K. Austen, 1996, Blood.

Aminoguanidine inhibits advanced glycation end products formation on beta2-microglobulin.

W. Owen, G. Chertow, J. Boyce, 1998, Journal of the American Society of Nephrology : JASN.

Beta 2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts.

R. O. Stuart, W. Owen, G. Chertow, 1998, Kidney international.

cysteinyl leukotriene-dependent mitogenic responses of mast cells CysLT2 receptors interact with CysLT1 receptors and down-modulate

B. Bacskai, Yongfeng Jiang, Y. Kanaoka, 2013 .

Adenine Nucleotides Inhibit Cytokine Generation by Human Mast Cells through a Gs-Coupled Receptor1

Chunli Feng, J. Boyce, A. Mery, 2004, The Journal of Immunology.

Syncytial Virus Infection Il-4 Expression Induced by Respiratory Stat1 Negatively Regulates Lung Basophil Stat1 Negatively Regulates Lung Basophil Il-4 Expression Induced by Respiratory Syncytial Virus Infection Il-4 Contributes to Immunopathology Induced in Mice by Primary Respiratory Syncytial Vir

Vrajesh V. Parekh, L. Kaer, D. Mitchell, 2022 .

STAT1 Negatively Regulates Lung Basophil IL-4 Expression Induced by Respiratory Syncytial Virus Infection1

Vrajesh V. Parekh, D. Mitchell, J. Boyce, 2009, The Journal of Immunology.

Interaction between β2-microglobulin and advanced glycation end products in the development of dialysis related-amyloidosis

W. Owen, G. Chertow, J. Boyce, 1997 .

Chemokine Generation by Human Mast Cells for Lysophosphatidic Acid-Mediated IL-4 Regulates MEK Expression Required

J. Boyce, D. Lin, D. A. Lin, 2005 .

IL-4 Regulates MEK Expression Required for Lysophosphatidic Acid-Mediated Chemokine Generation by Human Mast Cells1

J. Boyce, D. Lin, D. A. Lin, 2005, The Journal of Immunology.

Thymic Stromal Lymphopoietin Controls Prostaglandin D2 Generation in Aspirin-Exacerbated Respiratory Disease

E. Israel, N. Bhattacharyya, Chunli Feng, 2016 .

Characterization of a novel human mast cell line that responds to stem cell factor and expresses functional FcεRI.

J. Steinke, L. Borish, S. Paruchuri, 2011, The Journal of allergy and clinical immunology.

T Helper Cell Type 2 Cytokine–Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro

H. Ochi, D. Friend, K. Austen, 1999, The Journal of experimental medicine.

No audible wheezing

K. Austen, J. Boyce, K. Frank, 2005, The Journal of experimental medicine.

9 – Lipid Mediators of Hypersensitivity and Inflammation

J. Boyce, R. Peebles, 2014 .

Eicosanoid mediators of mast cells: receptors, regulation of synthesis, and pathobiologic implications.

J. Boyce, 2005, Chemical immunology and allergy.

Mast cells: beyond IgE.

J. Boyce, 2003, The Journal of allergy and clinical immunology.

CCR3 Is Required for Tissue Eosinophilia and Larval Cytotoxicity After Infection with Trichinella spiralis1

D. Friend, K. Austen, J. Boyce, 2002, The Journal of Immunology.

Lysophospholipids as mediators of immunity.

J. Boyce, D. Lin, D. A. Lin, 2006, Advances in immunology.

Human mast cells express multiple EP receptors for prostaglandin E2 that differentially modulate activation responses.

Chunli Feng, J. Boyce, S. Bagga, 2006, Blood.

Asthma 2005-2006: bench to bedside.

J. Boyce, 2006, The Journal of allergy and clinical immunology.

recruitment of mast cell progenitors to the inflamed lung Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for

K. Austen, J. Boyce, J. Abonia, 2013 .

Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung.

R. Flavell, K. Austen, J. Boyce, 2006, Blood.

No audible wheezing : nuggets and conundrums from mouse asthma models

K. Austen, J. Boyce, 2005 .

The role of mast cells in asthma.

J. Boyce, 2003, Prostaglandins, leukotrienes, and essential fatty acids.

Human Peripheral Blood Eosinophils Express a Functional c-kit Receptor for Stem Cell Factor that Stimulates Very Late Antigen 4 (VLA-4)–mediated Cell Adhesion to Fibronectin and Vascular Cell Adhesion Molecule 1 (VCAM-1)

M. Heidtman, D. Friend, K. Austen, 1997, The Journal of experimental medicine.

Advances in mechanisms of asthma, allergy, and immunology in 2011.

F. Finkelman, J. Boyce, M. Rothenberg, 2012, The Journal of allergy and clinical immunology.

Cysteinyl leukotrienes: biosynthesis and receptors

K. Austen, B. Lam, Y. Kanaoka, 2004 .

The Role of Mast Cells in Innate Immunity

K. Austen, J. Boyce, 2003 .

Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells

K. Austen, J. Boyce, A. Maekawa, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R

K. Austen, J. Boyce, J. Lora, 2003, Proceedings of the National Academy of Sciences of the United States of America.

COX‐1 mediates IL‐33–induced extracellular signal‐regulated kinase activation in mast cells: Implications for aspirin sensitivity

J. Boyce, S. K. Samuchiwal, H. Raff, 2019, The Journal of allergy and clinical immunology.

Coordinated Involvement of Mast Cells and T Cells in Allergic Mucosal Inflammation: Critical Role of the CC Chemokine Ligand 1:CCR8 Axis

C. Martínez-A, Q. Hamid, J. Villeval, 2007, The Journal of Immunology.

CCR 8 Axis Critical Role of the CC Chemokine Ligand Cells in Allergic Mucosal Inflammation : Coordinated Involvement of Mast Cells and

Kolbeck, Q. Hamid, J. Villeval, 2007 .

Biochemical and Functional Characterization of Human Transmembrane Tryptase (TMT)/Tryptase γ

P. Foster, J. Boyce, G. W. Wong, 2002, The Journal of Biological Chemistry.

Nasal polyp IgE and IgG4 levels are elevated in aspirin-exacerbated respiratory disease

N. Bhattacharyya, J. Boyce, T. Laidlaw, 2018 .

Mast cell lineage development and phenotypic regulation.

K. Austen, J. Boyce, 2001, Leukemia research.

Prostaglandin E2 Exerts Homeostatic Regulation of Pulmonary Vascular Remodeling in Allergic Airway Inflammation

S. Akira, W. Xing, Chunli Feng, 2009, The Journal of Immunology.

Novel Treatments for Airway Disease.

E. Israel, J. Boyce, K. Cahill, 2017, The New England journal of medicine.

The translational repressor T-cell intracellular antigen-1 (TIA-1) is a key modulator of Th2 and Th17 responses driving pulmonary inflammation induced by exposure to house dust mite.

P. Anderson, G. Giannattasio, W. Xing, 2012, Immunology letters.

Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report.

B. Yawn, R. Simon, F. Simons, 2011, Nutrition.

Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell.

J. Boyce, M. Gurish, 2006, The Journal of allergy and clinical immunology.

The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated

J. Drazen, D. Beier, K. Ackerman, 2011, Proceedings of the National Academy of Sciences.

Ras Guanine Nucleotide-releasing Protein-4 (RasGRP4) Involvement in Experimental Arthritis and Colitis*

P. Anderson, J. Boyce, P. Nigrovic, 2012, The Journal of Biological Chemistry.

Mast cell growth, differentiation, and death

J. Boyce, M. Gurish, 2002, Clinical reviews in allergy & immunology.

Mast Cells, Basophils, and Mastocytosis

J. Boyce, L. Fanning, Laura B. Fanning, 2019, Clinical Immunology.

LPA5 Is Abundantly Expressed by Human Mast Cells and Important for Lysophosphatidic Acid Induced MIP-1β Release

J. Boyce, A. Lundequist, 2011, PloS one.

CCR 3 Is Required for Tissue Eosinophilia and Larval Cytotoxicity After Infection with Trichinella spiralis 1

D. Friend, K. Austen, J. Boyce, 2002 .

Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.

E. Israel, N. Bhattacharyya, Chunli Feng, 2016, The Journal of allergy and clinical immunology.

Addition of mycophenolate mofetil to tacrolimus is associated with decreases in food-specific IgE levels in a pediatric patient with liver transplantation-associated food allergy.

J. Boyce, J. Cardet, 2013, The journal of allergy and clinical immunology. In practice.

LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma

E. Israel, Usha Govindarajulu, P. Ivester, 2014, SpringerPlus.

The Purinergic G Protein-Coupled Receptor 6 Inhibits Effector T Cell Activation in Allergic Pulmonary Inflammation

G. Giannattasio, W. Xing, J. Boyce, 2011, The Journal of Immunology.

Allergic Pulmonary Inflammation 6 Inhibits Effector T Cell Activation in The Purinergic G Protein-Coupled Receptor

G. Giannattasio, J. Boyce, S. Ohta, 2011 .

6 Inhibits Effector T Cell Activation in The Purinergic G Protein-Coupled Receptor

G. Giannattasio, J. Boyce, S. Ohta, 2011 .

Prostaglandin D2: A dominant mediator of aspirin exacerbated respiratory disease

J. Boyce, K. Cahill, Jillian Bensko, 2015 .

The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications.

K. Austen, Y. Kanaoka, J. Boyce, 2009, The Journal of allergy and clinical immunology.

Receptors Interact with CysLT 1 Receptors and Down-Modulate Cysteinyl Leukotriene-Dependent Mitogenic Responses of Mast Cells

B. Bacskai, Yongfeng Jiang, Y. Kanaoka, 2007 .

Leukotriene-Induced Signaling Autocrine / Intracrine Cysteinyl Cell Proliferation Requires Cutting Edge : Interleukin 4-Dependent

Yongfeng Jiang, Y. Kanaoka, Chunli Feng, 2006 .

Mast Cells May be Commandeered for Staphylococcal Pathogenicity in Chronic Rhinosinusitis with Nasal Polyposis.

J. Boyce, 2019, The Journal of allergy and clinical immunology.

Successful treatment of cold-induced urticaria/anaphylaxis with anti-IgE.

J. Boyce, 2006, The Journal of allergy and clinical immunology.

Human mast cell progenitors use alpha4-integrin, VCAM-1, and PSGL-1 E-selectin for adhesive interactions with human vascular endothelium under flow conditions.

F. Luscinskas, J. Boyce, Y. Lim, 2002, Blood.

Group V Secretory Phospholipase A2 Reveals Its Role in House Dust Mite-Induced Allergic Pulmonary Inflammation by Regulation of Dendritic Cell Function

D. Fujioka, G. Giannattasio, W. Xing, 2010, The Journal of Immunology.

Dendritic Cell Function Pulmonary Inflammation by Regulation of Its Role in House Dust Mite-Induced Allergic Reveals 2 Group V Secretory Phospholipase A

D. Fujioka, G. Giannattasio, W. Xing, 2010 .

Routine total skin examination to detect malignant melanoma

J. Boyce, J. Bernhard, 2007, Journal of General Internal Medicine.

Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.

S. Paruchuri, J. Boyce, C. Thodeti, 2016, The Journal of allergy and clinical immunology.

Group V Secretory Phospholipase A2 Is Involved in Macrophage Activation and Is Sufficient for Macrophage Effector Functions in Allergic Pulmonary Inflammation

W. Xing, J. Boyce, M. Imamura, 2013, The Journal of Immunology.

in Allergic Pulmonary Inflammation Sufficient for Macrophage Effector Functions Involved in Macrophage Activation and Is Is 2 Group V Secretory Phospholipase A

W. Xing, J. Boyce, M. Imamura, 2013 .

Updates on immune mechanisms in aspirin-exacerbated respiratory disease.

J. Boyce, T. Laidlaw, 2022, The Journal of allergy and clinical immunology.

Cysteinyl-maresin 3 inhibits IL-13 induced airway hyperresponsiveness through alternative activation of the CysLT1 receptor.

S. Dahlén, C. Wheelock, J. Boyce, 2022, European journal of pharmacology.

Generation of a novel stem cell factor-dependent mast cell progenitor.

D. Friend, K. Austen, J. Boyce, 1998, Journal of immunology.

Cell Factor-Dependent Mast Cell Progenitor Cutting Edge: Generation of a Novel Stem

D. Friend, K. Austen, J. Boyce, 1998 .

Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis.

J. Boyce, D. Dwyer, Daniel F. Dwyer, 2022, The Journal of allergy and clinical immunology.

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

S. Raychaudhuri, M. Gutierrez-Arcelus, R. Bergmark, 2022, bioRxiv.

FcepsilonRI-dependent gene expression in human mast cells is differentially controlled by T helper type 2 cytokines.

J. Boyce, J. Gutiérrez-Ramos, K. Price, 2003, The Journal of allergy and clinical immunology.

Human Mast Cell Progenitors Can Be Infected by Macrophagetropic Human Immunodeficiency Virus Type 1 and Retain Virus with Maturation In Vitro

J. Sodroski, H. Ochi, N. Bannert, 2001, Journal of Virology.

Mast cell biology in evolution.

D. Metcalfe, J. Boyce, 2006, The Journal of allergy and clinical immunology.

The pathobiology of eosinophilic inflammation.

J. Boyce, 1997, Allergy and asthma proceedings.

Risk factors for hospitalization, intensive care, and mortality among patients with asthma and COVID-19

J. Boyce, D. Bates, Li Zhou, 2020, Journal of Allergy and Clinical Immunology.

Regulation of Th9-type pulmonary immune responses: a new role for COX-2.

J. Boyce, R. Peebles, 2013, American journal of respiratory and critical care medicine.

Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel

A. Togias, A. Muraro, H. Sampson, 2017, Allergy, Asthma & Clinical Immunology.

Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–sponsored expert panel

A. Togias, A. Muraro, H. Sampson, 2017, Journal of Allergy and Clinical Immunology.

Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors

W. Owen, D. Friend, K. Austen, 1996 .

Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease.

E. Israel, J. Boyce, T. Laidlaw, 2019, The Journal of allergy and clinical immunology.

A new spin on mast cells and cysteinyl leukotrienes: Leukotriene E4 activates mast cells in vivo.

J. Boyce, L. Bankova, 2018, The Journal of allergy and clinical immunology.

Constitutive production of granulocyte/macrophage colony-stimulating factor by hypodense mononuclear eosinophils developed in vitro from hybrid eosinophil/basophil granulocytes.

W. Owen, D. Friend, K. Austen, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–sponsored expert panel

A. Togias, A. Muraro, H. Sampson, 2017, Journal of pediatric nursing.

Advances in mechanisms of allergy and clinical immunology in 2012.

F. Finkelman, J. Boyce, M. Rothenberg, 2013, The Journal of allergy and clinical immunology.

Olfactory microvillar tuft cells direct neurogenesis during allergic inflammation

Adam L. Haber, J. Boyce, Rachel E. Roditi, 2022 .

Legends of allergy and immunology: K. Frank Austen

J. Boyce, 2020, Allergy.

Coupled ReceptorsG Generation by Human Mast Cells through a Adenine Nucleotides Inhibit Cytokine

Chunli Feng, J. Boyce, A. Mery, 2004 .

Differentiation in vitro of hybrid eosinophil/basophil granulocytes: autocrine function of an eosinophil developmental intermediate

W. Owen, D. Friend, K. Austen, 1995, The Journal of experimental medicine.

Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts

Y. Kanaoka, J. Boyce, 2014, Allergy, asthma & immunology research.

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.

Carol Byrd-Bredbenner, Jon M Hanifin, Sami L Bahna, 2010, The Journal of allergy and clinical immunology.

Mechanisms of allergic diseases

D. Strachan, M. Moffatt, F. Finkelman, 2013 .

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Fabian J Theis, Alison Yu, Alex K. Shalek, 2020, Cell.

Prolonged anticonvulsant hypersensitivity syndrome related to lamotrigine in a patient with human immunodeficiency virus.

J. Boyce, Thomas C Beller, 2002, Allergy and Asthma Proceedings.

Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report.

Carol Byrd-Bredbenner, Jon M Hanifin, Sami L Bahna, 2011, Nutrition research.

Allergic inflammatory memory in human respiratory epithelial progenitor cells

Alex K. Shalek, Joshua A. Boyce, Travis K. Hughes, 2018, Nature.

Gene‐by‐environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma

J. Boyce, S. Bunyavanich, B. Raby, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation

Adam L. Haber, J. Boyce, I. Matsumoto, 2021, bioRxiv.

Type 2 Cysteinyl Leukotriene Receptors Drive IL-33–Dependent Type 2 Immunopathology and Aspirin Sensitivity

Y. Kanaoka, Chunli Feng, J. Boyce, 2018, The Journal of Immunology.

Prostaglandin D₂: a dominant mediator of aspirin-exacerbated respiratory disease.

J. Boyce, T. Laidlaw, K. Cahill, 2015, The Journal of allergy and clinical immunology.

Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics

E. Israel, Usha Govindarajulu, P. Ivester, 2013, Lipids in Health and Disease.

P2Y6 Receptors Require an Intact Cysteinyl Leukotriene Synthetic and Signaling System to Induce Survival and Activation of Mast Cells1

B. Bacskai, Yongfeng Jiang, Y. Kanaoka, 2009, The Journal of Immunology.

CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.

B. Bacskai, Yongfeng Jiang, Y. Kanaoka, 2007, Blood.

Cysteinyl Leukotrienes and Their Receptors: Cellular Distribution and Function in Immune and Inflammatory Responses1

Y. Kanaoka, J. Boyce, 2004, The Journal of Immunology.

Cysteinyl Leukotrienes and Uridine Diphosphate Induce Cytokine Generation by Human Mast Cells Through an Interleukin 4–regulated Pathway that Is Inhibited by Leukotriene Receptor Antagonists

K. Austen, J. Boyce, E. A. Mellor, 2002, The Journal of experimental medicine.

Interaction between beta 2-microglobulin and advanced glycation end products in the development of dialysis related-amyloidosis.

W. Owen, G. Chertow, J. Boyce, 1997, Kidney international.

The biology of the mast cell.

J. Boyce, 2004, Allergy and asthma proceedings.

Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation

K. Austen, J. Boyce, D. Dwyer, 2020, The Journal of experimental medicine.

Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel.

A. Togias, A. Muraro, H. Sampson, 2017, Journal of the Academy of Nutrition and Dietetics.

Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease.

A. Baccarelli, N. Bhattacharyya, H. Byun, 2016, American journal of respiratory cell and molecular biology.

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma

Allison Crosby-Thompson, E. Israel, S. Erzurum, 2017, The New England journal of medicine.

The role of 15 lipoxygenase 1 in asthma comes into focus

J. Boyce, 2022, The Journal of clinical investigation.

Macrophage P2Y6 Receptor Signaling Selectively Activates NFATC2 and Suppresses Allergic Lung Inflammation.

J. Boyce, J. Nagai, Junrui Lin, 2022, Journal of immunology.

P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation.

M. Idzko, P. Brennan, J. Boyce, 2019, The Journal of clinical investigation.

Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation

T. Hughes, A. Shalek, M. Nawijn, 2021, Science Immunology.

Macrophages regulate lung ILC2 activation via Pla2g5-dependent mechanisms

J. Boyce, O. Quehenberger, Munehiro Yamaguchi, 2017, Mucosal Immunology.

Lymphoplasmacytic Cells and Mast Cells Are Targets for Imatinib Mesylate (Gleevec, Glivec) in Waldenstrom’s Macroglobulinemia.

S. Treon, Z. Hunter, E. Hatjiharissi, 2004 .

Mast cells in Waldenstrom's macroglobulinemia support lymphoplasmacytic cell growth through CD154/CD40 signaling.

J. Kutok, S. Treon, Y. Tai, 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.

A. Togias, A. Muraro, H. Sampson, 2017, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Tuft cell–produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation

Adam L. Haber, J. Boyce, N. Barrett, 2021, Science Immunology.

Leukotriene E 4 Activates Peroxisome Proliferator-activated Receptor and Induces Prostaglandin D 2 Generation by

J. Plutzky, S. Paruchuri, Yongfeng Jiang, 2008 .

TRPM5+ microvillous tuft cells regulate neuroepithelial intrinsic olfactory stem cell proliferation

Adam L. Haber, J. Boyce, I. Matsumoto, 2023, bioRxiv.

FcεRI-dependent gene expression in human mast cells is differentially controlled by T helper type 2 cytokines

J. Boyce, J. Gutiérrez-Ramos, K. Price, 2003 .

Prostaglandin E2 Exerts Homeostatic Regulation of Pulmonary Vascular Remodeling in Allergic Airway Inflammation

S. Akira, W. Xing, Chunli Feng, 2009, The Journal of Immunology.

Development Of An Immortalized Stem Cell Factor (SCF)-independent Mast Cell Line Displaying High Concentrations Of FcɛRI

J. Steinke, L. Borish, S. Paruchuri, 2009 .

Addendum guidelines for the prevention of peanut allergy in the United States

A. Togias, A. Muraro, H. Sampson, 2017, Pediatric dermatology.

Key advances in mechanisms of asthma, allergy, and immunology in 2009.

F. Finkelman, J. Boyce, D. Vercelli, 2010, The Journal of allergy and clinical immunology.

Addendum guidelines for the prevention of peanut allergy in the United States.

A. Togias, A. Muraro, H. Sampson, 2017, JAAPA : official journal of the American Academy of Physician Assistants.

Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation

Chunli Feng, W. Xing, Chunli Feng, 2012, Proceedings of the National Academy of Sciences.

Glucagon‐like peptide‐1 receptor agonist use is associated with lower serum periostin

E. Karlson, P. Beeler, J. Cui, 2023, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

CC chemokine receptor 3 mobilizes to the surface of human mast cells and potentiates immunoglobulin E-dependent generation of interleukin 13.

D. Friend, J. Boyce, K. Price, 2003, American journal of respiratory cell and molecular biology.

IL-4 and -5 prime human mast cells for different profiles of IgE-dependent cytokine production.

H. Ochi, K. Austen, J. Boyce, 2000, Proceedings of the National Academy of Sciences of the United States of America.

CCR3 Is Required for Tissue Eosinophilia and Larval Cytotoxicity After Infection with Trichinella spiralis

D. Friend, K. Austen, J. Boyce, 2002, Journal of Immunology.

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-Exacerbated Respiratory Disease: A Prospective Trial.

E. Israel, J. Cui, J. Boyce, 2019, American journal of respiratory and critical care medicine.

ILC2 Are Activated By Macrophages through Pla2g5-Dependent Generation of Linoleic Acid and Oleic Acid

J. Boyce, Jannatul Firdous, Munehiro Yamaguchi, 2017 .

Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-depen

P. Foster, J. Boyce, G. W. Wong, 2002, The Journal of biological chemistry.

IL-5Rα marks nasal polyp IgG4 and IgE-secreting cells in aspirin-exacerbated respiratory disease

A. Shalek, N. Bhattacharyya, J. Boyce, 2019, bioRxiv.

IL-5Rα marks nasal polyp IgG4 and IgE-expressing cells in aspirin-exacerbated respiratory disease.

A. Shalek, N. Bhattacharyya, J. Boyce, 2020, The Journal of allergy and clinical immunology.

Samter's Immunologic Diseases

J. Schroeder, S. Holland, K. Austen, 2001 .

Title : IL-5 Rα marks nasal polyp IgG 4 and IgE-secreting cells in aspirin-exacerbated respiratory disease

A. Shalek, N. Bhattacharyya, J. Boyce, 2019 .

Systems Approaches to Treatment Response to Imatinib in Severe Asthma: A Pilot Study

E. Israel, S. Baek, J. Boyce, 2021, Journal of personalized medicine.

Group V Secretory Phospholipase A2 Is Involved in Macrophage Activation and Is Sufficient for Macrophage Effector Functions in Allergic Pulmonary Inflammation

W. Xing, J. Boyce, M. Imamura, 2013, The Journal of Immunology.

Gene‐by‐environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma

J. Boyce, S. Bunyavanich, B. Raby, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Lipid mediators and allergic diseases.

J. Boyce, Laura B. Fanning, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pathogenesis of aspirin-exacerbated respiratory disease and reactions.

J. Boyce, T. Laidlaw, 2013, Immunology and allergy clinics of North America.

Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.

E. Israel, N. Bhattacharyya, Chunli Feng, 2016, The Journal of allergy and clinical immunology.

Regulation of Th9-type pulmonary immune responses: a new role for COX-2.

J. Boyce, R. Peebles, 2013, American journal of respiratory and critical care medicine.

Total skin examination: patient reactions.

J. Boyce, J. Bernhard, 1986, Journal of the American Academy of Dermatology.

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.

B. Yawn, R. Simon, F. Simons, 2010, The Journal of allergy and clinical immunology.

Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.

S. Paruchuri, J. Boyce, C. Thodeti, 2016, The Journal of allergy and clinical immunology.

T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–dependent Cysteinyl Leukotriene Production by Human Cord Blood–derived Mast Cells: Profound Induction of Leukotriene C 4 Synthase Expression by Interleukin 4

B. Lam, J. Penrose, J. Boyce, 2001 .

Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35.

K. Austen, K. Xu, B. Lam, 1996, The Journal of biological chemistry.

Patient characteristics associated with reactions to Mrgprx2-activating drugs in an electronic health record-linked biobank.

Matthew Wien, E. Karlson, P. Brennan, 2022, Journal of Allergy and Clinical Immunology: In Practice.