D. Wisniewski

发表

Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein

Jilly F. Evans, Shihua Xu, A. Ferguson, 2007, Science.

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease

E. Scolnick, J. Hermes, R. Cummings, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Anthrax lethal factor inhibition

E. Scolnick, A. Woods, D. Zaller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Functional analysis of sites within PCSK9 responsible for hypercholesterolemias⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of one figure. Published, JLR Papers in Press, March 19, 2008.

R. Cummings, D. Wisniewski, S. Wright, 2008, Journal of Lipid Research.

The nuclear membrane organization of leukotriene synthesis

Jilly F. Evans, Phillip B. Jones, B. Hyman, 2008, Proceedings of the National Academy of Sciences.

Assay for IκB Kinases Using an in Vivo Biotinylated IκB Protein Substrate

P. Lograsso, D. Wisniewski, J. Calaycay, 1999 .

Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors.

Jilly F. Evans, A. Ferguson, Shihua Xu, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

The membrane organization of leukotriene synthesis.

Jilly F. Evans, B. Hyman, B. Bacskai, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cell-Based Assays to Detect Inhibitors of Fungal mRNA Capping Enzymes and Characterization of Sinefungin as a Cap Methyltransferase Inhibitor

S. A. Parent, G. Chrebet, D. Wisniewski, 2005, Journal of biomolecular screening.

PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.

Yang Li, Li Zhang, Guy Harris, 2008, Chemistry & biology.

Elucidation of DnaE as the Antibacterial Target of the Natural Product, Nargenicin.

B. Nare, F. Vicente, D. Wisniewski, 2015, Chemistry & biology.

Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin®.

J. Hermes, G. Scapin, N. Sharma, 2014, Bioorganic & medicinal chemistry letters.

Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation*

R. De Francesco, R. Cummings, D. Wisniewski, 2007, Journal of Biological Chemistry.

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

M. Erion, D. Kemp, S. Prahalada, 2017, Science.

Mechanism of activation for Zap-70 catalytic activity.

P. Lograsso, L. Frank, J. Hawkins, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Time-resolved Forster resonance energy transfer assays for the binding of nucleotide and protein substrates to p38alpha protein kinase.

J. Lisnock, P. Lograsso, R. Cummings, 2005, Analytical biochemistry.

Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712.

J. Hermes, G. Scapin, N. Sharma, 2011, Bioorganic & medicinal chemistry letters.

An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes

N. Geoghagen, L. Mitnaul, D. Johns, 2012, International journal of biological sciences.

Utilizing HaloTag Technology to Track the Fate of PCSK9 from Intracellular vs. Extracellular Sources

D. Wisniewski, B. Hubbard, O. Palyha, 2012, Current chemical genomics.

A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]

Lora Hamuro, Jayne Chin, L. Mitnaul, 2011, Journal of Lipid Research.

A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake

J. Condra, M. Bottomley, R. Cummings, 2010, The Journal of Biological Chemistry.

In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa

D. Wisniewski, M. Motyl, N. Murgolo, 2019, BMC Microbiology.

High-yield expression, refolding, and purification of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus strain 27R.

J. Hermes, L. Frank, D. Wisniewski, 1995, Protein expression and purification.

Assay for IkappaB kinases using an in vivo biotinylated IkappaB protein substrate.

P. Lograsso, D. Wisniewski, J. Calaycay, 1999, Analytical biochemistry.

C-terminal Loop Mutations Determine Folding and SecretionProperties of PCSK9

D. Johns, T. Vogt, D. Wisniewski, 2016 .