Douglas K. Miller

发表

Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein

Jilly F. Evans, Shihua Xu, A. Ferguson, 2007, Science.

Identification and isolation of a membrane protein necessary for leukotriene production

Jilly F. Evans, Jacques Yves Gauthier, Irving S. Sigal, 1990, Nature.

Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood

Geoffrey L. Chupp, Andrew A. Hill, Andrew J. Wardlaw, 2011, PloS one.

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

K. O. Elliston, Jayne Chin, J. Weidner, 1992, Nature.

The IL‐1β Converting Enzyme as a Therapeutic Target

N. Thornberry, S. Molineaux, Douglas K. Miller, 1993 .

The Interleukin-1 Receptor-associated Kinase Is Degraded by Proteasomes following Its Phosphorylation*

Douglas K. Miller, T. Yamin, Ting-Ting Yamin, 1997, The Journal of Biological Chemistry.

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Patrick R. Griffin, Y. Lazebnik, P. Griffin, 1995, Nature.

The interleukin‐1β converting enzyme family of cysteine proteases

Douglas K. Miller, J. W. Becker, J. Myerson, 1997 .

CPP32/Apopain Is a Key Interleukin 1 Converting Enzyme-like Protease Involved in Fas-mediated Apoptosis (*)

S. Orrenius, N. Thornberry, Douglas K. Miller, 1996, The Journal of Biological Chemistry.

Interleukin-1β-converting enzyme and related proteases as potential targets in inflammation and apoptosis

N. Thornberry, Douglas K. Miller, D. Nicholson, 1995 .

Molecular Cloning and Pro-apoptotic Activity of ICErelII and ICErelIII, Members of the ICE/CED-3 Family of Cysteine Proteases (*)

S. Molineaux, Douglas K. Miller, T. Yamin, 1995, The Journal of Biological Chemistry.

IL-13 as a therapeutic target for respiratory disease.

Douglas K. Miller, M. Kasaian, 2008, Biochemical pharmacology.

Actin cleavage by CPP-32/apopain during the development of apoptosis

T. Tsuruo, M. Naito, T. Mashima, 1997, Oncogene.

The nuclear membrane organization of leukotriene synthesis

Jilly F. Evans, Phillip B. Jones, B. Hyman, 2008, Proceedings of the National Academy of Sciences.

Entry of Enveloped Viruses into Cells

Douglas K. Miller, J. Lenard, 1983 .

Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.

D. Zaller, Amjad Ali, Douglas K. Miller, 2004, Journal of medicinal chemistry.

Leukotrienes and Asthma

R. Dixon, J. Metzger, D. Riendeau, 1992 .

Biological Mechanism Associated with Asthma Exacerbation Attack as Revealed By Gene Expression Patterns of Peripheral Blood Mononuclear Cells

U. Bjornsdottir, P. Thompson, S. Holgate, 2009 .

Skin-Specific Caspase-1-Transgenic Mice Show Cutaneous Apoptosis and Pre-Endotoxin Shock Condition with a High Serum Level of IL-181

H. Okamura, R. Black, T. Kupper, 2000, The Journal of Immunology.

Therapeutic potential of 5-lipoxygenase inhibitors: the discovery and development of MK-886, a novel-mechanism leukotriene inhibitor

R. Dixon, C. Yoakim, C. Rouzer, 1992 .

Processing proIL-1β decreases detection by a proIL-1β specific ELISA but increases detection by a conventional ELISA

Douglas K. Miller, M. Wewers, H. Pope, 1993 .

Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy.

D. Zaller, Amjad Ali, Douglas K. Miller, 2005, Bioorganic & Medicinal Chemistry Letters.

Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors.

Jilly F. Evans, A. Ferguson, Shihua Xu, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

The membrane organization of leukotriene synthesis.

Jilly F. Evans, B. Hyman, B. Bacskai, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Development of a high-capacity homogeneous fluorescent assay for the measurement of leukotriene B4.

R. Cummings, Douglas K. Miller, T. Yamin, 2006, Analytical biochemistry.

Serum Level of IL-18 Pre-Endotoxin Shock Condition with a High Show Cutaneous Apoptosis and Skin-Specific Caspase-1-Transgenic Mice

H. Okamura, R. Black, T. Kupper, 2000 .

Characterization and Quantitation of NF-κB Nuclear Translocation Induced by Interleukin-1 and Tumor Necrosis Factor-α

Douglas K. Miller, R. Boltz, A. Gough, 1998, The Journal of Biological Chemistry.

Uncoating of enveloped viruses

Douglas K. Miller, J. Lenard, 1982, Cell.

Chapter 26. Regulation of Apoptosis by Members of the ICE Family and the Bcl-2 Family

Douglas K. Miller, 1996 .

Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experiments.

D. Zaller, Amjad Ali, Douglas K. Miller, 2007, Bioorganic & medicinal chemistry letters.

Activation of Apoptosis and Its Inhibition

Douglas K. Miller, 1999, Annals of the New York Academy of Sciences.

Activation of the Native 45-kDa Precursor Form of Interleukin-1-converting Enzyme*

Douglas K. Miller, T. Yamin, J. Ayala, 1996, The Journal of Biological Chemistry.

Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity.

Scott K. Smith, D. Zaller, Amjad Ali, 2005, Bioorganic & Medicinal Chemistry Letters.

Sequential activation of three distinct ICE‐like activities in Fas‐ligated Jurkat cells

D. K. Miller, Douglas K. Miller, T. Yamin, 1996, FEBS letters.

Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

R. Dixon, R. Diehl, J. Evans, 1990, Nature.

Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.

D. K. Miller, Douglas K. Miller, A. Rosen, 1994, The Journal of biological chemistry.

The role of the Caspase family of cysteine proteases in apoptosis.

Douglas K. Miller, D. K. Miller, 1997, Seminars in immunology.

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy

J. Weidner, Douglas K. Miller, K. Chapman, 1995, The Journal of experimental medicine.

IL-1 beta-converting enzyme is present in monocytic cells as an inactive 45-kDa precursor.

Douglas K. Miller, T. Yamin, J. Chin, 1994, Journal of immunology.