F. Ujjainwalla

发表

Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein

Jilly F. Evans, Shihua Xu, A. Ferguson, 2007, Science.

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

B. Hawes, K. O'neill, J. Lisnock, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Design and syntheses of melanocortin subtype-4 receptor agonists: evolution of the pyridazinone archetype.

F. Ujjainwalla, L. V. D. van der Ploeg, C. Rosenblum, 2003, Bioorganic & medicinal chemistry letters.

Discovery of phenyl acetamides as potent and selective GPR119 agonists.

V. Hornak, A. Woods, A. Stamford, 2017, Bioorganic & Medicinal Chemistry Letters.

Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects.

Michael F. Finley, John J. Cummings, A. Crespo, 2016, Bioorganic & medicinal chemistry letters.

Leukotriene B4 Strongly Increases Monocyte Chemoattractant Protein-1 in Human Monocytes

Jilly F. Evans, M. Struthers, F. Ujjainwalla, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.

J. Huber, F. Ujjainwalla, L. V. D. van der Ploeg, 2008, Bioorganic & medicinal chemistry letters.

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists.

F. A. Romero, F. Ujjainwalla, A. Howard, 2018, ACS medicinal chemistry letters.

Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes.

F. Ujjainwalla, E. Sherer, R. Nargund, 2016, Bioorganic & medicinal chemistry letters.

Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors.

Jilly F. Evans, L. Chu, F. Ujjainwalla, 2012, Bioorganic & medicinal chemistry letters.

Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors.

Jilly F. Evans, A. Ferguson, Shihua Xu, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Madin-Darby Canine Kidney II Cells: A Pharmacologically Validated System for NPC1L1-Mediated Cholesterol Uptake

F. Ujjainwalla, M. Braun, Y. S. Tang, 2008, Molecular Pharmacology.

Taxane diterpenes 4: Autoxidation, epimerization and isomerization for the introduction of functionality into the taxane ABC ring system

V. Lynch, N. Westwood, F. Ujjainwalla, 1998 .

Taxane diterpenes 1. Control of relative and absolute stereochemistry in intramolecular pyrylium ylide-alkene cyclizations for the synthesis of taxol precursors

James G. Tarrant, William Bauta, F. Ujjainwalla, 1996 .

Isomerization, autoxidation and epimerization for the introduction of C-1 to C-5 functionality into the taxane ABC ring system

V. Lynch, N. Westwood, F. Ujjainwalla, 1996 .

Fragment-Based Lead Discovery of a Novel Class of Small Molecule Inhibitors of Neuropeptide B/W Receptor Subtype 1 (GPR7).

Zhiqian Guo, N. Hastings, F. Ujjainwalla, 2020, Bioorganic & medicinal chemistry letters.

Synthesis of 5-, 6- and 7-azaindoles via palladium-catalyzed heteroannulation of internal alkynes

F. Ujjainwalla, Daniel Warner, 1998 .

Total syntheses of 6- and 7-azaindole derived GnRH antagonists

F. Ujjainwalla, T. F. Walsh, 2001 .

Steric and electronic effects in the synthesis of biaryls and their heterocyclic congeners using intramolecular free radical [1,5] ipso substitution reactions

F. Ujjainwalla, W. Motherwell, M. L. E. N. Mata, 1997 .

Observations on the nature of the tethering chain in the synthesis of biaryls and heterobiaryls via intramolecular free radical ipso substitution reactions.

F. Ujjainwalla, W. Motherwell, M. L. E. N. Mata, 1997 .

Tri-n-butylstannyl radical induced rearrangement of homopropargyl (but-3-ynyl) arenesulfonates: a route to novel 4-aryl-5,6-dihydro-1,2-oxathiin 2,2-dioxides

F. Ujjainwalla, W. Motherwell, A. Pennell, 1992 .

A convergent synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists

F. Ujjainwalla, M. Goulet, Jonathan R. Young, 2001 .

New strategy for the synthesis of the taxane diterpenes: Formation of the BC-rings of taxol via a [5+2]-pyrylium ylide-alkene cyclization, ring expansion strategy

James G. Tarrant, William Bauta, F. Ujjainwalla, 1995 .

Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: discovery of the dihydropyridazinone motif.

F. Ujjainwalla, L. V. D. van der Ploeg, R. Tang, 2005, Bioorganic & medicinal chemistry letters.

Observations on the nature of the tethering chain in the synthesis of biaryls and heterobiaryls via intramolecular free radical ipso substitution reactions.

F. Ujjainwalla, W. Motherwell, M. L. E. N. Mata, 1997 .

A concise approach towards the synthesis of steganone analogues

F. Ujjainwalla, W. Motherwell, Adrian Bradley, 1999 .

New strategy for the synthesis of the taxane diterpenes: Formation of the A-ring and introduction of the C-1 hydroxyl group

James G. Tarrant, F. Ujjainwalla, P. Magnus, 1995 .

Synthesis of biaryls via intramolecular free radical ipso-substitution reactions

S. Vázquez, F. Ujjainwalla, C. Escolano, 2015 .

A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor.

R. DeVita, F. Ujjainwalla, D. Macintyre, 2001, Journal of medicinal chemistry.

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.

R. DeVita, F. Ujjainwalla, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the BC-Rings of Taxol via a (5 + 2) Pyrylium Ylide-Alkene Cyclization, Ring Expansion Strategy.

James G. Tarrant, William Bauta, F. Ujjainwalla, 1995 .

Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia.

C. Chiu, J. Metzger, Liming Yang, 2018, ACS medicinal chemistry letters.

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes.

F. Ujjainwalla, E. Sherer, A. Howard, 2016, ACS medicinal chemistry letters.

Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with in Vivo Activity in Rodents.

Charles L. Jayne, F. Ujjainwalla, T. Akiyama, 2017, ACS medicinal chemistry letters.

The discovery of potent antagonists of NPBWR1 (GPR7).

Zhiqian Guo, N. Hastings, F. Ujjainwalla, 2012, Bioorganic & medicinal chemistry letters.

Small molecule ligands of the human melanocortin-4 receptor.

F. Ujjainwalla, I. Sebhat, 2007, Current topics in medicinal chemistry.

Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists.

A. Crespo, E. Tozzo, F. Ujjainwalla, 2017, ACS medicinal chemistry letters.

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.

R. DeVita, F. Ujjainwalla, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension.

M. Struthers, D. Macneil, D. Cully, 2017, Bioorganic & medicinal chemistry letters.

Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant Hypertension.

M. Struthers, D. Macneil, D. Cully, 2017, ACS medicinal chemistry letters.