Keiko Yamamoto

发表

Structural basis for the activation of PPARgamma by oxidized fatty acids.

J. Schwabe, T. Itoh, L. Fairall, 2008, Nature structural & molecular biology.

Functions of key residues in the ligand-binding pocket of vitamin D receptor: Fragment molecular orbital interfragment interaction energy analysis

Hiroaki Tokiwa, Kenji Yamagishi, Keiko Yamamoto, 2006 .

Flexible ligand recognition of peroxisome proliferator-activated receptor-gamma (PPARgamma).

Hiroaki Tokiwa, Yuji Mochizuki, Tatsuya Nakano, 2010, Bioorganic & medicinal chemistry letters.

Structural basis of species differences between human and experimental animal CYP1A1s in metabolism of 3,3',4,4',5-pentachlorobiphenyl.

H. Inui, Motoharu Suzuki, T. Itoh, 2011, Journal of biochemistry.

Intravenous and oral administrations of DD2 [7-Amino-2-(sulfanylmethyl)heptanoic acid] produce thrombolysis through inhibition of plasma TAFIa in rats with tissue factor-induced microthrombosis.

H. Yamazaki, K. Sugimoto, Keiko Yamamoto, 2012, Thrombosis research.

Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.

Keiko Yamamoto, S. Yamada, M. Shimizu, 2006, Bioorganic & medicinal chemistry.

New derivatives of 1α, 25-dihydroxy-19-norvitamin D3 with two substituents at C-2: synthesis and biological activity

Keiko Yamamoto, S. Yamada, M. Shimizu, 2005 .

Previtamin D3 with a trans-Fused Decalin CD-ring Has Pronounced Genomic Activity*

R. Bouillon, Keiko Yamamoto, G. Eelen, 2003, Journal of Biological Chemistry.

Stereoselective syntheses of (22R)- and (22S)-22-methyl-1.alpha.,25-dihydroxyvitamin D3: active vitamin D3 analogs with restricted side-chain conformation

H. DeLuca, Keiko Yamamoto, S. Yamada, 1993 .

Syntheses of 1-Alkyl-1,25-dihydroxyvitamin D3

Keiko Yamamoto, S. Yamada, M. Shimizu, 1995 .

On the side chain conformation of 1α,25-dihydroxyvitamin D3 responsible for binding to the receptor

H. DeLuca, Keiko Yamamoto, S. Yamada, 1995 .

2-Methylene 19-nor-25-dehydro-1alpha-hydroxyvitamin D3 26,23-lactones: synthesis, biological activities and molecular basis of passive antagonism.

M. Makishima, Y. Inaba, Keiko Yamamoto, 2008, Bioorganic & medicinal chemistry.

Type-Selective Vitamin D Receptor Modulators

M. Makishima, Y. Inaba, Keiko Yamamoto, 2007 .

Vitamin D3 Derivatives with Adamantane or Lactone Ring Side Chains are Cell Type-Selective Vitamin D Receptor Modulators

M. Makishima, Y. Inaba, Keiko Yamamoto, 2007, Molecular Pharmacology.

Potent Antiproliferative Effects of 25‐Hydroxy‐16‐ene‐23‐yne‐vitamin D3 That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1

J. Welsh, M. Uskoković, T. Itoh, 2014, Journal of cellular biochemistry.

Metabolism of vitamin D3 by cytochromes P450.

N. Kagawa, K. Inouye, Keiko Yamamoto, 2005, Frontiers in bioscience : a journal and virtual library.

The roles of cytochrome P450 enzymes in prostate cancer development and treatment.

Keiko Yamamoto, Tai-Chi Chen, T. Sakaki, 2012, Anticancer research.

17-OxoDHA Is a PPARα/γ Dual Covalent Modifier and Agonist.

T. Itoh, Keiko Yamamoto, Y. Akiyama, 2016, ACS chemical biology.

Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1.

N. Kagawa, S. Kato, K. Inouye, 2006, Biochemistry.

Identification of the Amino Acid Residue of CYP27B1 Responsible for Binding of 25-Hydroxyvitamin D3 Whose Mutation Causes Vitamin D-dependent Rickets Type 1*

N. Kagawa, S. Kato, K. Inouye, 2005, Journal of Biological Chemistry.

Structure-Function Analysis of Vitamin D 24-Hydroxylase (CYP24A1) by Site-Directed Mutagenesis: Amino Acid Residues Responsible for Species-Based Difference of CYP24A1 between Humans and Rats

K. Inouye, Keiko Yamamoto, S. Yamada, 2006, Molecular Pharmacology.

Mild oxidation of aldehydes to the corresponding carboxylic acids and esters: alkaline iodine oxidation revisited

Keiko Yamamoto, S. Yamada, D. Morizono, 1992 .

Development of novel lithocholic acid derivatives as vitamin D receptor agonists.

N. Ito, T. Ikura, H. Kagechika, 2019, Bioorganic & medicinal chemistry.

Mammalian Cytochrome P450-Dependent Metabolism of Polychlorinated Dibenzo-p-dioxins and Coplanar Polychlorinated Biphenyls

H. Inui, S. Ikushiro, T. Itoh, 2014, International journal of molecular sciences.

Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1

S. Kato, S. Ikushiro, Keiko Yamamoto, 2007, Drug Metabolism and Disposition.

Role of Gln 85 of human CYP27A1 in 25-hydroxyvitamin D(3)-binding and protein folding.

K. Inouye, S. Ikushiro, Keiko Yamamoto, 2007, Biochemical and biophysical research communications.

Activation of testicular orphan receptor 4 by fatty acids.

Pawan Gupta, H. Kagechika, Keiko Yamamoto, 2009, Biochimica et biophysica acta.

Construction of a series of intermediates in the β-oxidation pathway from THA to EPA via DHA in free acid form.

T. Itoh, Keiko Yamamoto, H. Ishida, 2018, Bioorganic & medicinal chemistry.

Gram scale synthesis of specialized pro-resolving mediator 17(S)-HDHA using lipoxygenase enhanced by water-soluble reducing agent TCEP.

T. Itoh, Keiko Yamamoto, Yoshinori Yamamoto, 2016, Bioorganic & medicinal chemistry letters.

Structural Basis for the Activation of Pparg by Oxidised Fatty Acids

J. Schwabe, T. Itoh, L. Fairall, 2008 .

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells

N. LeBrasseur, J. Flanagan, T. Itoh, 2011, The Journal of Steroid Biochemistry and Molecular Biology.

Structure-Function Analysis of Vitamin D 24-Hydroxylase ( CYP 24 A 1 ) by Site-Directed Mutagenesis : Amino Acid Residues Responsible for Species-Based Difference of CYP 24 A 1 between Humans and Rats

K. Inouye, Keiko Yamamoto, S. Yamada, 2006 .

Selective inhibition of methoxyflavonoids on human CYP1B1 activity.

T. Itoh, Keiko Yamamoto, K. Shimoi, 2010, Bioorganic & medicinal chemistry.

Differences in Enantioselective Hydroxylation of 2,2',3,6-Tetrachlorobiphenyl (CB45) and 2,2',3,4',6-Pentachlorobiphenyl (CB91) by Human and Rat CYP2B Subfamilies.

H. Inui, T. Itoh, Keiko Yamamoto, 2022, Environmental science & technology.

1&agr;,25-Dihydroxyvitamin D3 and Its Potent Synthetic Analogs Downregulate Tissue Factor and Upregulate Thrombomodulin Expression in Monocytic Cells, Counteracting the Effects of Tumor Necrosis Factor and Oxidized LDL

Keiko Yamamoto, T. Koyama, S. Hirosawa, 2000, Circulation.

Helix12-Stabilization Antagonist of Vitamin D Receptor.

T. Itoh, Keiko Yamamoto, Y. Anami, 2016, Bioconjugate chemistry.

Ligand recognition by vitamin D receptor: total alanine scanning mutational analysis of the residues lining the ligand binding pocket of vitamin D receptor.

Keiko Yamamoto, S. Yamada, 2006, Current topics in medicinal chemistry.

Kinetic Studies of 25-Hydroxy-19-nor-vitamin D 3 and 1 (cid:1) ,25-Dihydroxy-19-nor-vitamin D 3 Hydroxylation by CYP27B1 and CYP24A1

S. Kato, S. Ikushiro, Keiko Yamamoto, 2007 .

Stereoselective synthesis and structural establishment of (25S)-24,24-difluoro-1α,25,26-trihydroxyvitamin D3, a major metabolite of 24,24-difluoro-1α,25-dihydroxyvitamin D3

Keiko Yamamoto, Y. Miyamoto, S. Yamada, 1998 .

Possibility of application of cytochrome P450 to bioremediation of dioxins

S. Ikushiro, Keiko Yamamoto, T. Sakaki, 2013, Biotechnology and applied biochemistry.

HNF4α Is a Covalent Bond-Forming Receptor.

T. Itoh, Keiko Yamamoto, N. Ohashi, 2021, Journal of nutritional science and vitaminology.

Metabolism of vitamin D3 by cytochromes P450.

N. Kagawa, K. Inouye, Keiko Yamamoto, 2005, Frontiers in bioscience : a journal and virtual library.

CYP24A1 as a potential target for cancer therapy.

K. Yasuda, Keiko Yamamoto, Tai-Chi Chen, 2014, Anti-cancer agents in medicinal chemistry.

17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist

T. Itoh, Keiko Yamamoto, Y. Akiyama, 2016 .

Efficient Synthesis of the Very-Long-Chain n-3 Fatty Acids, Tetracosahexaenoic Acid (C24:6n-3) and Tricosahexaenoic Acid (C23:6n-3)

T. Itoh, Keiko Yamamoto, Ayako Tomiyasu, 2011, Lipids.

1α,25-Dihydroxyvitamin D3-24-Hydroxylase (CYP24) Hydroxylates the Carbon at the End of the Side Chain (C-26) of the C-24-fluorinated Analog of 1α,25-Dihydroxyvitamin D3 *

Keiko Yamamoto, Y. Miyamoto, S. Yamada, 1997, The Journal of Biological Chemistry.

Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands.

T. Itoh, Keiko Yamamoto, N. Yoshimoto, 2018, Journal of medicinal chemistry.

Synthesis and determination of the stereochemistry of 23,25-dihydroxy-24-oxovitamin D3, a major metabolite of 24(R),25-dihydroxyvitamin D3

A. Itai, Keiko Yamamoto, S. Yamada, 1989 .

Synthesis and structure-activity relationships of 16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes.

H. DeLuca, N. Udagawa, Keiko Yamamoto, 2008, Bioorganic & medicinal chemistry.

Inclusion complexation of (cyclo)alkanes and (cyclo) alkanols with 6-O-modified cyclodextrins

Keiko Yamamoto, Y. Inoue, T. Wada, 1998 .

Three-Component Regioselective Synthesis of Tetrahydrofuro[2,3-d]oxazoles and Their Efficient Conversion to Oxazoles

T. Itoh, Keiko Yamamoto, A. Saito, 2017 .

Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2‐arachidonoyl‐glycerol and its congeners in human myeloid leukocytes

L. Boulet, A. Veilleux, N. Flamand, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

New photoisomerization of provitamin D caused by hydroxylation at C(1)

Keiko Yamamoto, S. Yamada, Hiroki Ishida, 1995 .

4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor gamma agonist alleviates the symptoms of DSS-induced colitis.

Y. Okazaki, N. Petrovsky, T. Itoh, 2008, Biochemical and biophysical research communications.

22S-Butyl-1α,24R-dihydroxyvitamin D3: Recovery of vitamin D receptor agonistic activity

N. Ito, T. Ikura, T. Itoh, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.

N. Ito, T. Ikura, Y. Inaba, 2009, Journal of medicinal chemistry.

Palladium-catalyzed coupling reaction of chloropyrazines with indole

Keiko Yamamoto, A. Inoue, M. Shimizu, 1985 .

Inclusion-Enhanced Optical Yield and E/Z Ratio in Enantiodifferentiating Photoisomerization of Cyclooctene Included and Sensitized by .beta.-Cyclodextrin Monobenzoate

Keiko Yamamoto, Y. Inoue, A. Tai, 1995 .

Biomimetic total synthesis of (+/-)-8-oxoerymelanthine.

T. Itoh, Keiko Yamamoto, K. Mohri, 2009, The Journal of organic chemistry.

Diastereoselectivity and Mechanism of Conjugate Addition of Organocuprates to γ-Chiral Acyclic Enones and Enoates

Keiko Yamamoto, S. Yamada, 1999 .

Stereochemical and Mechanistic Studies on Conjugate Addition of Organocuprates to Acyclic Enones and Enoates: Simple Rule for Diastereofacial Selectivity

Keiko Yamamoto, S. Yamada, H. Ogura, 1998 .

Molecular Recognition Study on a Supramolecular System. 10.1 Inclusion Complexation of Modified β-Cyclodextrins with Amino Acids: Enhanced Enantioselectivity for l/d-Leucine

Yu Liu, Keiko Yamamoto, A. Qi, 1997 .

Oligoarginine-Conjugated Peptide Foldamers Inhibiting Vitamin D Receptor-Mediated Transcription

T. Kurohara, Keiko Yamamoto, Y. Kanda, 2022, ACS omega.

SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity.

T. Itoh, Keiko Yamamoto, Y. Anami, 2017, Bioorganic & medicinal chemistry.

Analysis of structural features of bis-quaternary ammonium antimicrobial agents 4,4′-(α,ω-Polymethylenedithio)bis (1-alkylpyridinium iodide)s using computational simulation

H. Nagamune, K. Ohkura, T. Maeda, 2003 .

Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.

T. Itoh, Y. Inaba, Keiko Yamamoto, 2013, Journal of medicinal chemistry.

Comparison of Metabolism of Sesamin and Episesamin by Drug-Metabolizing Enzymes in Human Liver

K. Yasuda, S. Ikushiro, T. Itoh, 2012, Drug Metabolism and Disposition.

Microsoft Word-74863913-file00

K. Yasuda, S. Ikushiro, T. Itoh, 2012 .

Design and synthesis of selective CYP1B1 inhibitor via dearomatization of α-naphthoflavone.

T. Itoh, Keiko Yamamoto, M. Kubo, 2019, Bioorganic & medicinal chemistry.

High-performance capillary zone electrophoresis of carbohydrates in the presence of alkaline earth metal ions

Susumu Honda, Keiko Yamamoto, Shigeo Suzuki, 1991 .

Capillary zone electrophoresis of reducing mono- and oligo-saccharides as the borate complexes of their 3-methyl-1-phenyl-2-pyrazolin-5-one derivatives

Susumu Honda, Keiko Yamamoto, Shigeo Suzuki, 1991 .

Synthesis of docosahexaenoic acid derivatives designed as novel PPARgamma agonists and antidiabetic agents.

T. Itoh, Keiko Yamamoto, Kazuyoshi Yoshikai, 2006, Bioorganic & medicinal chemistry.

Identification of putative metabolites of docosahexaenoic acid as potent PPARgamma agonists and antidiabetic agents.

T. Itoh, Keiko Yamamoto, S. Yamada, 2005, Bioorganic & medicinal chemistry letters.

A 3D Model of CYP1B1 Explains the Dominant 4-Hydroxylation of Estradiol

Keiko Yamamoto, Toshimasa Itoh, Hitomi Takemura, 2010, J. Chem. Inf. Model..

Geometrical Isomerism of Phenylhydrazones of α-Keto Esters. II. p-Substituted Phenylhydrazones of Ethyl Pyruvate and 2,4-Dinitrophenylhydrazones of Some α-Keto Esters

Keiko Yamamoto, Y. Kitagawa, A. Matsuoka, 1986 .

A study of synthetic approaches to 2-acyl DHA lysophosphatidic acid.

T. Itoh, Keiko Yamamoto, Yoshinori Yamamoto, 2017, Organic & biomolecular chemistry.

Phagocytic cells metabolize 25‐hydroxyvitamin D3 to 10‐oxo‐19‐nor‐25‐hydroxyvitamin D3 and a new metabolite, 8α,25‐dihydroxy‐9, 10‐seco‐4,6,10(19)‐cholestatrien‐3‐one

Hirofumi Tanaka, Keiko Yamamoto, S. Yamada, 1987, FEBS letters.

Insights into PPARγ phosphorylation and its inhibition mechanism.

A. Heck, A. Paiardini, A. Grottesi, 2020, Journal of medicinal chemistry.

The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor.

C. Morimoto, Keiko Yamamoto, S. Yamada, 2005, Molecular endocrinology.

Structural basis for the activation of PPARγ by oxidized fatty acids

J. Schwabe, T. Itoh, L. Fairall, 2008, Nature Structural &Molecular Biology.

Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases

Keiko Yamamoto, S. Yamada, T. Shinki, 2006, Steroids.

Homology modeling of human 25-hydroxyvitamin D3 1α-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5

Hiroyuki Masuno, K. Inouye, Keiko Yamamoto, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Design and characterization of a selenium-containing inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa), a zinc-containing metalloprotease.

K. Sugimoto, Keiko Yamamoto, N. Yoshimoto, 2012, Journal of medicinal chemistry.

Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group.

T. Itoh, Keiko Yamamoto, N. Yoshimoto, 2018, Bioorganic & medicinal chemistry letters.

Three-dimensional structure-function relationship of vitamin D and vitamin D receptor model

Keiko Yamamoto, S. Yamada, Mihwa Choi, 2001, Steroids.

Vitamin D receptor.

Keiko Yamamoto, S. Yamada, M. Shimizu, 2003, Endocrine development.

Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics.

M. Ikeguchi, Toru Ekimoto, N. Shimizu, 2016, Journal of medicinal chemistry.

Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.

N. Ito, T. Ikura, T. Itoh, 2015, Bioorganic & medicinal chemistry.

Structure–function relationships of vitamin D including ligand recognition by the vitamin D receptor

Keiko Yamamoto, S. Yamada, M. Shimizu, 2003, Medicinal research reviews.

Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.

N. Ito, H. Kagechika, Keiko Yamamoto, 2020, Journal of medicinal chemistry.

Synthesis of Oxidized Fatty Acid Derivatives via an Iodolactonization Reaction

T. Itoh, Keiko Yamamoto, N. Yoshimoto, 2010 .

Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands.

N. Ito, T. Itoh, Y. Inaba, 2012, Journal of medicinal chemistry.

Potent antagonist for the vitamin D receptor: vitamin D analogues with simple side chain structure.

Y. Inaba, Keiko Yamamoto, N. Yoshimoto, 2010, Journal of medicinal chemistry.

Vitamin D Analogues with a p-Hydroxyphenyl Group at the C25 Position: Crystal Structure of Vitamin D Receptor Ligand-Binding Domain Complexed with the Ligand Explains the Mechanism Underlying Full Antagonistic Action.

T. Itoh, Keiko Yamamoto, H. Ishida, 2017, Journal of medicinal chemistry.

A mixed population of antagonist and agonist binding conformers in a single crystal explains partial agonism against vitamin D receptor: active vitamin D analogues with 22R-alkyl group.

T. Itoh, Keiko Yamamoto, N. Yoshimoto, 2014, Journal of medicinal chemistry.

The synthesis of oligosaccharide-branched cyclodextrins and their interaction with concanavalin A

Keiko Yamamoto, K. Hattori, T. Inazu, 1996 .

Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass Spectrometry.

T. Itoh, Keiko Yamamoto, N. Ohashi, 2023, Journal of medicinal chemistry.

Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins.

H. Kojima, T. Itoh, Keiko Yamamoto, 2020, Cell chemical biology.

On-site reaction for PPARγ modification using a specific bifunctional ligand.

H. Kojima, T. Itoh, Keiko Yamamoto, 2017, Bioorganic & medicinal chemistry.

Metabolic enhancement of 2,3',4,4',5-pentachlorobiphenyl (CB118) using cytochrome P450 monooxygenase isolated from soil bacterium under the presence of perfluorocarboxylic acids (PFCAs) and the structural basis of its metabolism.

H. Inui, O. Shoji, T. Itoh, 2018, Chemosphere.

Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3).

H. DeLuca, M. Makishima, Keiko Yamamoto, 2007, Archives of biochemistry and biophysics.

Characterization of covalent bond formation between PPARγ and oxo-fatty acids.

T. Itoh, Keiko Yamamoto, D. Egawa, 2015, Bioconjugate chemistry.

Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand

T. Itoh, Keiko Yamamoto, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Structural determinants for vitamin D receptor response to endocrine and xenobiotic signals.

M. Makishima, I. Shimomura, D. Mangelsdorf, 2004, Molecular endocrinology.

Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists

N. Ito, T. Ikura, H. Kagechika, 2019 .

From the Cover: Structural Determinants of the Position of 2,3',4,4',5-Pentachlorobiphenyl (CB118) Hydroxylation by Mammalian Cytochrome P450 Monooxygenases.

H. Inui, T. Itoh, Keiko Yamamoto, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor.

H. DeLuca, Y. Inaba, Keiko Yamamoto, 2007, Journal of medicinal chemistry.

Rational design, synthesis, and biological activity of novel conformationally restricted vitamin D analogues, (22R)- and (22S)-22-ethyl-1,25-dihydroxy-23,24-didehydro-24a,24b-dihomo-20-epivitamin D(3).

Keiko Yamamoto, S. Yamada, T. Shinki, 2002, Journal of medicinal chemistry.

Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.

H. DeLuca, M. Makishima, D. Mangelsdorf, 2003, Chemistry & biology.

Two-dimensional alanine scanning mutational analysis of the interaction between the vitamin D receptor and its ligands: studies of A-ring modified 19-norvitamin D analogs

Keiko Yamamoto, S. Yamada, M. Shimizu, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Ligand recognition by the vitamin D receptor.

Keiko Yamamoto, S. Yamada, K. Nakashima, 2001, Bioorganic & medicinal chemistry.

Highly diastereoselective conjugate addition of organocuprate to acyclic E- and Z-enones: Reversal Stereoselectivity under kinetic and thermodynamic conditions

Keiko Yamamoto, S. Yamada, K. Yamaguchi, 1992 .

Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.

N. Udagawa, Keiko Yamamoto, M. Takami, 2006, Bioorganic & medicinal chemistry.

Vitamin D receptor: ligand recognition and allosteric network.

M. Makishima, Keiko Yamamoto, N. Yoshimoto, 2006, Journal of medicinal chemistry.

Syntheses of 1‐Alkyl‐1,25‐dihydroxyvitamin D3.

Keiko Yamamoto, S. Yamada, M. Shimizu, 1995 .

Structure–function relationships of vitamin D including ligand recognition by the vitamin D receptor

Keiko Yamamoto, S. Yamada, M. Shimizu, 2003, Medicinal research reviews (Print).

Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position.

H. DeLuca, Keiko Yamamoto, S. Yamada, 2007, Bioorganic & medicinal chemistry.

Stereoselective Syntheses of (22R)‐ and (22S)‐22‐Methyl‐1α,25‐ dihydroxyvitamin D3: Active Vitamin D3 Analogs with Restricted Side Chain Conformation.

H. DeLuca, Keiko Yamamoto, S. Yamada, 1993 .

Biomimetic oxidation of vitamin D by iron-sulfur model cluster and dioxygen system

Keiko Yamamoto, S. Yamada, Y. Imae, 1990 .

Highly Diastereoselective Conjugate Addition of Organocuprate to Acyclic E- and Z-Enones: Reversal Stereoselectivity Under Kinetic and Thermodynamic Conditions.

Keiko Yamamoto, S. Yamada, K. Yamaguchi, 1993 .

Conformationally Restricted Analogues of 1α,25‐Dihydroxyvitamin D3 and Its 20‐Epimer: Compounds for Study of the Three‐Dimensional Structure of Vitamin D Responsible for Binding to the Receptor.

H. DeLuca, Keiko Yamamoto, S. Yamada, 1996 .

Alanine scanning mutational analysis of the ligand binding pocket of the human Vitamin D receptor

Keiko Yamamoto, S. Yamada, M. Shimizu, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics.

M. Ikeguchi, Toru Ekimoto, N. Shimizu, 2016, Journal of medicinal chemistry.