B. Fitzsimmons

发表

Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord

Edward A. Dennis, Tony L. Yaksh, E. Dennis, 2010, Journal of neurochemistry.

Intrathecal neurosteroids and a neurosteroid antagonist: Effects on inflammation-evoked thermal hyperalgesia and tactile allodynia

B. Fitzsimmons, T. Yaksh, Elin Svensson, 2013, Neuroscience Letters.

Descending serotonergic facilitation of spinal ERK activation and pain behavior

C. Svensson, B. Fitzsimmons, X. Hua, 2006, FEBS letters.

Spinal p38β isoform mediates tissue injury‐induced hyperalgesia and spinal sensitization

C. Svensson, B. Fitzsimmons, X. Hua, 2005, Journal of neurochemistry.

Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug–unresponsive hyperalgesia in male rats

A. Jadhav, E. Dennis, A. Simeonov, 2018, Pain.

Systematic analysis of rat 12/15‐lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia

E. Dennis, D. Dumlao, Matthew W Buczynski, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Intrathecal minocycline attenuates peripheral inflammation‐induced hyperalgesia by inhibiting p38 MAPK in spinal microglia

C. Svensson, B. Fitzsimmons, X. Hua, 2005, The European journal of neuroscience.

Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a TNF dependent mechanism

Arpita, B. Fitzsimmons, Jae-Hang Shim, 2012 .

kinase isoform reduces neuropathic and postoperative pain and TLR 4-induced pain in male mice

B. Fitzsimmons, N. Terrando, R. Ji, 2017 .

Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice

B. Fitzsimmons, R. Ji, Lin-lin Zhang, 2017, Brain, Behavior, and Immunity.

Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats.

A. Jadhav, E. Dennis, A. Simeonov, 2018 .

Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain

B. Fitzsimmons, H. Kordasiewicz, E. Swayze, 2018, Pain.

In Vivo Gene Knockdown in Rat Dorsal Root Ganglia Mediated by Self-Complementary Adeno-Associated Virus Serotype 5 Following Intrathecal Delivery

B. Fitzsimmons, X. Hua, A. Miyanohara, 2012, PloS one.

Inhibition of spinal cytosolic phospholipase A2 expression by an antisense oligonucleotide attenuates tissue injury-induced hyperalgesia

D. H. Kim, C. Svensson, B. Monia, 2008, Neuroscience.

Spinal astrocytes produce and secrete dynorphin neuropeptides

B. Fitzsimmons, T. Yaksh, Lydiane Funkelstein, 2013, Neuropeptides.

Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors

Edward A Dennis, B. Taylor, E. Dennis, 2012, Proceedings of the National Academy of Sciences.

Role of spinal p38α and β MAPK in inflammatory hyperalgesia and spinal COX-2 expression

C. Svensson, B. Fitzsimmons, X. Hua, 2010, Neuroreport.

Inhibition of spinal constitutive NOS‐2 by 1400W attenuates tissue injury and inflammation‐induced hyperalgesia and spinal p38 activation

C. Svensson, B. Fitzsimmons, X. Hua, 2007, The European journal of neuroscience.

Evaluation of spinal toxicity and long-term spinal reflex function following intrathecal levobupivacaine in the neonatal rat

B. Fitzsimmons, 2015 .

Evaluation of Spinal Toxicity and Long-term Spinal Reflex Function after Intrathecal Levobupivaciane in the Neonatal Rat

S. Walker, M. Grafe, B. Fitzsimmons, 2013, Anesthesiology.

Spinal Phosphinositide 3-Kinase–Akt–Mammalian Target of Rapamycin Signaling Cascades in Inflammation-Induced Hyperalgesia

A. Newton, B. Fitzsimmons, X. Hua, 2011, The Journal of Neuroscience.

Development of a simple, rapid, and robust intrathecal catheterization method in the rat

F. Kamme, B. Fitzsimmons, C. Mazur, 2017, Journal of Neuroscience Methods.

Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Prostaglandin E2 Release

E. Dennis, C. Svensson, D. Hadjipavlou-Litina, 2006, Journal of Pharmacology and Experimental Therapeutics.

Mechanisms of antinociception of spinal galanin: how does galanin inhibit spinal sensitization?

I. Kondo, B. Fitzsimmons, X. Hua, 2005, Neuropeptides.

Galanin Acts at GalR1 Receptors in Spinal Antinociception: Synergy with Morphine and AP-5

T. Bártfai, Ű. Langel, B. Fitzsimmons, 2004, Journal of Pharmacology and Experimental Therapeutics.

Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a tumor necrosis factor-dependent mechanism

B. Fitzsimmons, Jae-Hang Shim, X. Hua, 2012, Neuroscience.

Spinal release of tumour necrosis factor activates c-Jun N-terminal kinase and mediates inflammation-induced hypersensitivity

S. Codeluppi, B. Fitzsimmons, S. Abdelmoaty, 2014, European journal of pain.

Design of the First-in-Human Study of IONIS-MAPTRx, a Tau-lowering Antisense Oligonucleotide, in Patients With Alzheimer Disease (S2.006)

L. Mignon, B. Fitzsimmons, D. Norris, 2018 .

Convective forces increase rostral delivery of intrathecal radiotracers and antisense oligonucleotides in the cynomolgus monkey nervous system

Jenna M. Sullivan, J. Hoppin, Nicolas Currier, 2020, Journal of Translational Medicine.

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

C. Mummery, J. Rinne, M. Jonsson, 2023, Nature Medicine.

Systemic and intrathecal effects of a novel series of phospholipase A 2 inhibitors on hyperalgesia and spinal PGE 2 release

E. Dennis, C. Svensson, D. Hadjipavlou-Litina, 2005 .

Convective forces increase rostral delivery of intrathecal antisense oligonucleotides in the cynomolgus monkey nervous system

Jenna M. Sullivan, J. Hoppin, Nicolas Currier, 2020, bioRxiv.

Acetaminophen prevents hyperalgesia in central pain cascade

B. Fitzsimmons, X. Hua, T. Yaksh, 2008, Neuroscience Letters.

Role of spinal p38α and β MAPK in inflammatory hyperalgesia and spinal COX-2 expression

C. Svensson, B. Fitzsimmons, X. Hua, 2010, Neuroreport.