R. Godemann

发表

The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease.

E. Mandelkow, E. Mandelkow, U. Preuss, 1998, Molecular biology of the cell.

Fragment-based discovery of BACE1 inhibitors using functional assays.

R. Godemann, T. Hesterkamp, A. Cesura, 2009, Biochemistry.

Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease

E. Mandelkow, S. Illenberger, K. Stamer, 1998, The Journal of cell biology.

Phosphorylation of tau protein by recombinant GSK‐3β: pronounced phosphorylation at select Ser/Thr‐Pro motifs but no phosphorylation at Ser262 in the repeat domain

E. Mandelkow, J. Biernat, R. Godemann, 1999, FEBS letters.

Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease

A. Drzezga, R. Godemann, M. Schoor, 2009, PloS one.

Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity

E. Mandelkow, E. Mandelkow, K. Stamer, 2000 .

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K).

Adam R. Johnson, Jianwen A. Feng, Brandon J. Bravo, 2017, Journal of medicinal chemistry.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase.

Jianwen A. Feng, P. McEwan, Lawren C. Wu, 2018, Journal of medicinal chemistry.

The multiple roles of computational chemistry in fragment-based drug design

Mark Whittaker, Ole Andersen, Richard Law, 2009, J. Comput. Aided Mol. Des..

Filling a nick in NIK: extending the half-life of a NIK inhibitor through structure-based drug design.

Matthew L Landry, P. McEwan, Adam Johnson, 2023, Bioorganic & medicinal chemistry letters.

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.

E. Mandelkow, E. Mandelkow, S. Illenberger, 1998, European journal of biochemistry.

Fragment-based discovery and optimization of BACE1 inhibitors.

Joachim Kraemer, Thomas Hesterkamp, Robert Godemann, 2010, Bioorganic & medicinal chemistry letters.

Structure Based Design of Potent Selective Inhibitors of Protein Kinase D1 (PKD1).

Jianwen A. Feng, P. McEwan, R. Godemann, 2019, ACS medicinal chemistry letters.

Phosphorylation of tau protein by recombinant GSK‐3β: pronounced phosphorylation at select Ser/Thr‐Pro motifs but no phosphorylation at Ser262 in the repeat domain

E. Mandelkow, J. Biernat, R. Godemann, 1999, FEBS letters.