S. Dewhurst

发表

Platelet-activating Factor Receptor Activation

Y. Hannun, L. Epstein, G. Dbaibo, 1998, The Journal of Biological Chemistry.

Zinc Pyrithione Improves the Antibacterial Activity of Silver Sulfadiazine Ointment

D. Krysan, S. Dewhurst, R. A. Wozniak, 2016, mSphere.

Mathematical Modeling of Ultradeep Sequencing Data Reveals that Acute CD8+ T-Lymphocyte Responses Exert Strong Selective Pressure in Simian Immunodeficiency Virus-Infected Macaques but Still Fail To Clear Founder Epitope Sequences

Tanzy M. T. Love, S. Dewhurst, H. Y. Lee, 2010, Journal of Virology.

Transient overexpression of κ and μ opioid receptors using recombinant adenovirus vectors

S. Dewhurst, J. Bidlack, B. Bradel-Tretheway, 2004, Journal of Neuroscience Methods.

Valproic acid enhances gene expression from viral gene transfer vectors.

S. Dewhurst, B. Bradel-Tretheway, S. Ramirez, 2005, Journal of virological methods.

Effects of zidovudine use during pregnancy on resistance and vertical transmission of human immunodeficiency virus type 1.

S. Dewhurst, L. Demeter, R. Reichman, 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The New Small-Molecule Mixed-Lineage Kinase 3 Inhibitor URMC-099 Is Neuroprotective and Anti-Inflammatory in Models of Human Immunodeficiency Virus-Associated Neurocognitive Disorders

M. Tremblay, Shao-ming Lu, E. Muly, 2013, The Journal of Neuroscience.

Human herpesvirus 6

S. Dewhurst, D. Skrincosky, N. Van Loon, 1997, Expert Reviews in Molecular Medicine.

Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells.

J. Schlesinger, S. Dewhurst, Ramil E. Sapinoro, 2008, Virology.

PA Residues in the 2009 H1N1 Pandemic Influenza Virus Enhance Avian Influenza Virus Polymerase Activity in Mammalian Cells

H. Bussey, Baek Kim, S. Dewhurst, 2011, Journal of Virology.

Stringent structural and sequence requirements of the human herpesvirus 6B lytic-phase origin of DNA replication.

C Dykes, S. Dewhurst, C. Dykes, 1997, The Journal of general virology.

Identification of a lytic-phase origin of DNA replication in human herpesvirus 6B strain Z29

P. Pellett, S. Dewhurst, T. Dambaugh, 1993, Journal of virology.

Molecular Testing for HHV-6 Infection

S. Dewhurst, B. Bradel-Tretheway, 2006 .

Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo.

D. Benoit, S. Dewhurst, S. Arany, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal

S. Perry, S. Dewhurst, H. Gelbard, 2004, Journal of neuroscience research.

Human Herpesvirus 6 A Coding Content and Comparison with Human Herpesvirus 6 B Genome Sequence :

N. Inoue, S. Dewhurst, T. Dambaugh, 1999 .

Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens.

S. Dewhurst, S. Ramirez, C. Maguire, 2006, Vaccine.

Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform.

S. Dewhurst, Matthew G. Brewer, Jonelle L. Mattiacio, 2017, Methods in molecular biology.

Dense display of HIV-1 envelope spikes on the lambda phage scaffold does not result in the generation of improved antibody responses to HIV-1 Env.

S. Walter, S. Dewhurst, William Domm, 2011, Vaccine.

Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure

R. Frisina, J. Walton, S. Dewhurst, 2010, Hearing Research.

Chronic Central Nervous System Expression of HIV‐1 Tat Leads to Accelerated Rarefaction of Neocortical Capillaries and Loss of Red Blood Cell Velocity Heterogeneity

Jharon N. Silva, S. Dewhurst, C. Feng, 2014, Microcirculation.

Expression of glial fibrillary acidic protein in human glioma cell lines as detected by molecular hybridization

S. Dewhurst, D. Volsky, R. Mccomb, 1987, Acta Neuropathologica.

Development of a Mouse-Adapted Live Attenuated Influenza Virus That Permits In Vivo Analysis of Enhancements to the Safety of Live Attenuated Influenza Virus Vaccine

Steven F. Baker, S. Dewhurst, A. Nogales, 2014, Journal of Virology.

Epitope mapping of human herpesvirus-7 gp65 using monoclonal antibodies

P. Mirandola, S. Dewhurst, X. Wang, 2001, Archives of Virology.

A Novel Antipathogenic Agent for Nonwoven Fabric

S. Dewhurst, B. Bal, R. Bock, 2022, Biomedical Materials & Devices.

Leucine-Rich Repeat Kinase 2 Modulates Neuroinflammation and Neurotoxicity in Models of Human Immunodeficiency Virus 1-Associated Neurocognitive Disorders

Shao-ming Lu, S. Dewhurst, H. Gelbard, 2015, The Journal of Neuroscience.

Neuronal Fractalkine Expression in HIV-1 Encephalitis: Roles for Macrophage Recruitment and Neuroprotection in the Central Nervous System1

Sandra A. Kinnear, H. Gendelman, T. Schall, 2000, The Journal of Immunology.

Human Dendritic Cells Transduced with Herpes Simplex Virus Amplicons Encoding Human Immunodeficiency Virus Type 1 (HIV-1) gp120 Elicit Adaptive Immune Responses from Human Cells Engrafted into NOD/SCID Mice and Confer Partial Protection against HIV-1 Challenge

H. Gendelman, H. Federoff, S. Dewhurst, 2005, Journal of Virology.

9G4 Autoreactivity Is Increased in HIV-Infected Patients and Correlates with HIV Broadly Neutralizing Serum Activity

D. Montefiori, C. Labranche, S. Dewhurst, 2012, PloS one.

Identification and Analysis of a Novel Heparin-Binding Glycoprotein Encoded by Human Herpesvirus 7

B. Chandran, P. Secchiero, S. Dewhurst, 2000, Journal of Virology.

Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells.

S. Dewhurst, P. Sime, D. Topham, 2010, Virology.

CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

H. Gendelman, S. Dewhurst, C. Gebhart, 2010, The Journal of Immunology.

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2−/−γc−/− Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2006, Journal of Virology.

Inhibition of HIV type 1 replication using lentiviral-mediated delivery of mutant tRNA(Lys3)A58U.

R. Bambara, S. Dewhurst, V. Planelles, 2004, AIDS research and human retroviruses.

Advances in HIV microbicide development.

S. Dewhurst, David Easterhoff, J. Olsen, 2011, Future medicinal chemistry.

Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS

S. Dewhurst, Yuanan Lu, Yongbo Yang, 2011, Journal of Neuroinflammation.

Semen-Derived Enhancer of Viral Infection (SEVI) Binds Bacteria, Enhances Bacterial Phagocytosis by Macrophages, and Can Protect against Vaginal Infection by a Sexually Transmitted Bacterial Pathogen

Jharon N. Silva, S. Dewhurst, C. Feng, 2013, Antimicrobial Agents and Chemotherapy.

Oligovalent amyloid-binding agents reduce SEVI-mediated enhancement of HIV-1 infection.

S. Dewhurst, Jerry Yang, J. Olsen, 2012, Journal of the American Chemical Society.

Inhibition of the enhancement of infection of human immunodeficiency virus by semen-derived enhancer of virus infection using amyloid-targeting polymeric nanoparticles.

S. Dewhurst, Jerry Yang, Lauren R Brooks, 2015, ACS nano.

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2-/- Î3c-/- Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2019 .

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB / cRag 2 / c / Mice

H. Gendelman, S. Dewhurst, J. Sharp, 2017 .

Human Immunodeﬁciency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2 Mice (cid:1)

H. Gendelman, S. Dewhurst, J. Sharp, 2007 .

Proteasome blockers inhibit TNF-α release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia

L. Epstein, S. Dewhurst, H. Gelbard, 1999, Journal of Neuroimmunology.

Amyloid-binding Small Molecules Efficiently Block SEVI (Semen-derived Enhancer of Virus Infection)- and Semen-mediated Enhancement of HIV-1 Infection*

R. Srivastava, S. Dewhurst, B. Nilsson, 2010, The Journal of Biological Chemistry.

Pathogenesis of simian immunodeficiency virus infection.

S. Dewhurst, L. Whetter, F. Novembre, 1999, The Journal of general virology.

Neuropathogenesis of AIDS.

S. Dewhurst, H. Gelbard, S. Fine, 1996, Molecular medicine today.

H. Gendelman, H. Federoff, S. Dewhurst, 2019 .

Expression of the T4 molecule (AIDS virus receptor) by human brain‐derived cells

S. Dewhurst, D. Volsky, M. Stevenson, 1987, FEBS letters.

Activation of glycogen synthase kinase 3 beta (GSK‐3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons

S. Dewhurst, H. Gelbard, S. Maggirwar, 2001, The European journal of neuroscience.

Adenovirus type 7 penton

R. Ruigrok, G. Schoehn, S. Dewhurst, 2000 .

MLK3 regulates fMLP-stimulated neutrophil motility.

S. Dewhurst, H. Gelbard, Minsoo Kim, 2014, Molecular immunology.

Classification of HHV-6A and HHV-6B as distinct viruses

H. Agut, U. Gompels, P. Pellett, 2014, Archives of Virology.

Murine Cytomegalovirus Abortively Infects Human Dendritic Cells, Leading to Expression and Presentation of Virally Vectored Genes

S. Dewhurst, M. Messerle, Xia Jin, 2003, Journal of Virology.

Resources for HIV/AIDS on the Internet.

D. M. Sander, S. Dewhurst, J. Sgro, 1996, Molecular medicine today.

A Live Attenuated Influenza Vaccine Elicits Enhanced Heterologous Protection When the Internal Genes of the Vaccine Are Matched to Those of the Challenge Virus

S. Dewhurst, D. Topham, A. Nogales, 2019, Journal of Virology.

Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection

D. Mathews, T. Mariani, J. Thakar, 2022, bioRxiv.

A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells.

S. Dewhurst, L. Whetter, Shikha Chakraborty-Sett, 2003, European journal of biochemistry.

Human herpesvirus-6 infection in children. A prospective study of complications and reactivation.

L. Epstein, S. Dewhurst, C. Hall, 1994, The New England journal of medicine.

Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.

H. Gendelman, G. Schifitto, S. Dewhurst, 2007, Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.

U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture.

A. Gonelli, S. Dewhurst, A. Rotola, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Dendritic Cell-Targeted Phage Vectors for Breast Cancer Vaccine Development

S. Dewhurst, 2002 .

Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag.

H. Federoff, S. Dewhurst, W. Bowers, 2007, Vaccine.

Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14.

S. Dewhurst, H. Gelbard, L. Whetter, 1998, Virology.

Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy.

L. Epstein, S. Dewhurst, C. Hall, 1995, Journal of neurovirology.

Phenotypic and genetic polymorphisms among human herpesvirus-6 isolates from North American infants.

B. Chandran, S. Dewhurst, C. Hall, 1992, Virology.

Identification and analysis of a lytic-phase origin of DNA replication in human herpesvirus 7

S. Dewhurst, C. Dykes, J. Nicholas, 1997, Journal of virology.

Telomeric sequences from human herpesvirus 6 do not mediate nuclear retention of episomal DNA in human cells

S. Dewhurst, M. Calos, G. H. Bulboaca, 1998, Archives of Virology.

Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14.

S. Dewhurst, H. Gelbard, S. Gummuluru, 1996, Virology.

Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier.

S. Dewhurst, J. McGrath, W. Bowers, 2011, Vaccine.

Luciferase: a sensitive and quantitative probe for blood-brain barrier disruption

L. Epstein, H. Federoff, S. Dewhurst, 1998, Journal of Neuroscience Methods.

HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime.

H. Federoff, S. Dewhurst, W. Bowers, 2007, Vaccine.

Costimulatory Pathways in Lymphocyte Proliferation Induced by the Simian Immunodeficiency Virus SIVsmmPBj14

S. Dewhurst, L. Whetter, S. Gummuluru, 1998, Journal of Virology.

Human herpesvirus-6 strain groups: a nomenclature

H. Agut, L. Montagnier, B. Chandran, 1993, Archives of Virology.

Use of bacteriophage particles displaying influenza virus hemagglutinin for the detection of hemagglutination-inhibition antibodies.

Steven F. Baker, J. Treanor, S. Dewhurst, 2014, Journal of virological methods.

9G4+ Antibodies Isolated from HIV-Infected Patients Neutralize HIV-1 and Have Distinct Autoreactivity Profiles

S. Dewhurst, C. Dykes, I. Sanz, 2013, PloS one.

Human herpesvirus 6.

S. Dewhurst, M. Caserta, L. Strausbaugh, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The Human Herpesvirus 6 G Protein-Coupled Receptor Homolog U51 Positively Regulates Virus Replication and Enhances Cell-Cell Fusion In Vitro

S. Dewhurst, J. Bidlack, B. Bradel-Tretheway, 2005, Journal of Virology.

A live-attenuated influenza vaccine (LAIV) elicits enhanced heterologous protection when the internal genes of the vaccine are matched to the challenge virus

S. Dewhurst, A. Nogales, L. Martínez-Sobrido, 2019 .

In vivo gene delivery and expression by bacteriophage lambda vectors

S. Dewhurst, C. Capella, K. Santos, 2007, Journal of applied microbiology.

G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells

R. Bambara, S. Dewhurst, S. Maggirwar, 2020, Cell cycle.

Tumor Necrosis Factor α Inhibits Glutamate Uptake by Primary Human Astrocytes

J. Rothstein, L. Epstein, S. Perry, 1996, The Journal of Biological Chemistry.

Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine

R. Albrecht, A. García-Sastre, S. Dewhurst, 2022, Microbiology spectrum.

Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.

H. Gendelman, S. Dewhurst, J. Sharp, 2007, Journal of virology.

Ganciclovir Inhibits Human Adenovirus Replication and Pathogenicity in Permissive Immunosuppressed Syrian Hamsters

R. Buller, S. Dewhurst, W. Wold, 2014, Antimicrobial Agents and Chemotherapy.

Human Salivary Glands Immunohistochemical Assessment of Fractalkine, Inflammatory Cells, and Human Herpesvirus 7 in

S. Dewhurst, H. Gelbard, L. Latchney, 2013 .

Immunohistochemical Assessment of Fractalkine, Inflammatory Cells, and Human Herpesvirus 7 in Human Salivary Glands

S. Dewhurst, H. Gelbard, L. Latchney, 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Functional Identification and Analysis ofcis-Acting Sequences Which Mediate Genome Cleavage and Packaging in Human Herpesvirus 6

H. Deng, S. Dewhurst, 1998, Journal of Virology.

HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells

Jason R. Myers, S. Dewhurst, J. Ashton, 2017, ACS chemical biology.

False‐positive enzyme‐linked immunosorbent assay reactions for antibody to human immunodeficiency virus in a population of midwestern patients with congenital bleeding disorders

S. Dewhurst, D. Volsky, Douglas M. Smith, 1987, Transfusion.

Testing for antibodies to AIDS‐associated retrovirus (HTLV‐III/LAV) by indirect fixed cell immunofluorescence: Specificity, sensitivity, and applications

S. Dewhurst, D. Volsky, F. Sinangil, 1986, Journal of medical virology.

HIV-1 Tat Induces Neuronal Death via Tumor Necrosis Factor-α and Activation of Non-N-methyl-d-aspartate Receptors by a NFκB-Independent Mechanism*

L. Epstein, S. Dewhurst, H. Gelbard, 1998, The Journal of Biological Chemistry.

A tractable method for simultaneous modifications to the head and tail of bacteriophage lambda and its application to enhancing phage-mediated gene delivery

S. Dewhurst, B. Bradel-Tretheway, Ramil E. Sapinoro, 2007, Nucleic acids research.

Prevalence of AIDS-associated retrovirus and antibodies among male homosexuals at risk for AIDS in Greenwich Village.

S. Dewhurst, D. Volsky, F. Sinangil, 1984, AIDS research.

Neomycin Sulfate Improves the Antimicrobial Activity of Mupirocin-Based Antibacterial Ointments

S. Dewhurst, P. Dunman, Catlyn Blanchard, 2015, Antimicrobial Agents and Chemotherapy.

A simple method for the production of specific antiserum to the second nuclear antigen (EBNA-2) of Epstein-Barr virus (EBV).

S. Dewhurst, D. Volsky, 1986, Journal of immunological methods.

13 – Simian Immunodeficiency Virus (SIV) from Old World Monkeys

J. Mullins, C. Contag, S. Dewhurst, 1991 .

Evaluating the Antimicrobial Properties of Commercial Hand Sanitizers

S. Dewhurst, P. Dunman, M. Chojnacki, 2021, mSphere.

Human papillomavirus-like particles mediate functional delivery of plasmid DNA to antigen presenting cells in vivo.

C. Malboeuf, S. Dewhurst, H. Lankes, 2007, Vaccine.

Tumor Necrosis Factor (cid:97) Inhibits Glutamate Uptake by Primary Human Astrocytes FOR PATHOGENESIS OF HIV-1

J. Rothstein, L. Epstein, S. Perry, 2022 .

The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate.

Baek Kim, S. Dewhurst, C. Hergott, 2009, Biochemistry.

Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A.

L. Epstein, S. Dewhurst, C. Hall, 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The tyrosine-17 residue of Nef in SIVsmmPBj14 is required for acute pathogenesis and contributes to replication in macrophages.

H. McClure, S. Dewhurst, F. Novembre, 1998, Virology.

Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine

S. Dewhurst, L. Frenkel, L M Frenkel, 1995, Journal of clinical microbiology.

Pharmacologic Inhibition of MLK3 Kinase Activity Blocks the In Vitro Migratory Capacity of Breast Cancer Cells but Has No Effect on Breast Cancer Brain Metastasis in a Mouse Xenograft Model

S. Dewhurst, H. Gelbard, C. Feng, 2014, PloS one.

Neurotrophins prevent HIV Tat‐induced neuronal apoptosis via a nuclear factor‐κB (NF‐κB)‐dependent mechanism

S. Dewhurst, H. Gelbard, S. Maggirwar, 2001 .

Nerve Growth Factor-Dependent Activation of NF-κB Contributes to Survival of Sympathetic Neurons

R. Freeman, S. Dewhurst, S. Maggirwar, 1998, The Journal of Neuroscience.

Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors.

T. Foster, H. Federoff, S. Dewhurst, 2007, Human gene therapy.

Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants

S. Dewhurst, C. Hall, K. Schnabel, 1993, Journal of clinical microbiology.

Enhanced responsiveness to nuclear factor kappa B contributes to the unique phenotype of simian immunodeficiency virus variant SIVsmmPBj14

P. Fultz, S. Dewhurst, S. Gummuluru, 1994, Journal of virology.

Molecular clones from a non-acutely pathogenic derivative of SIVsmmPBj14: characterization and comparison to acutely pathogenic clones.

J. Mullins, P. Fultz, S. Dewhurst, 1992, AIDS research and human retroviruses.

Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14

J. Mullins, P. Fultz, S. Dewhurst, 1990, Nature.

Adenoviral Vector Driven by a Minimal Rad51 Promoter Is Selective for p53-Deficient Tumor Cells

A. Seluanov, V. Gorbunova, S. Dewhurst, 2011, PloS one.

Human immunodeficiency virus‐encoded Tat activates glycogen synthase kinase‐3β to antagonize nuclear factor‐κB survival pathway in neurons

S. Dewhurst, H. Gelbard, M. Potash, 2006 .

Establishment of human glial cell lines chronically infected with the human immunodeficiency virus.

S. Dewhurst, D. Volsky, K. Sakai, 1988, Virology.

Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA

H. Gendelman, L. Epstein, S. Perry, 1995, Molecular and cellular biology.

Persistent productive infection of human glial cells by human immunodeficiency virus (HIV) and by infectious molecular clones of HIV

S. Dewhurst, D. Volsky, M. Stevenson, 1987, Journal of virology.

Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro

I. Harris, S. Dewhurst, J. Munger, 2020, bioRxiv.

Human Herpesvirus 6B Genome Sequence: Coding Content and Comparison with Human Herpesvirus 6A

N. Inoue, P. Pellett, S. Dewhurst, 1999, Journal of Virology.

Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus

R. Bambara, S. Dewhurst, R. Lanier, 2018, Antimicrobial Agents and Chemotherapy.

Efficient gene transfer into human monocyte-derived macrophages using defective lentiviral vectors.

S. Dewhurst, V. Planelles, L. Zeng, 2003, Cellular and molecular biology.

Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: A therapeutic strategy based on modulation of mixed lineage kinase

H. Gendelman, S. Dewhurst, H. Gelbard, 2010, Neurotherapeutics.

Pathogenesis and treatment of HIV-1 infection: recent developments (Y2K update).

S. Dewhurst, L. Whetter, R. L. da Cruz, 2000, Frontiers in bioscience : a journal and virtual library.

Pathogenesis and treatment of HIV-1 infection: recent developments.

S. Dewhurst, L. Whetter, 1997, Frontiers in bioscience : a journal and virtual library.

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

Pauline E. Chugh, Baek Kim, S. Dewhurst, 2008, Retrovirology.

Neuroinvasion and persistence of human herpesvirus 6 in children.

L. Epstein, S. Dewhurst, C. Hall, 1994, The Journal of infectious diseases.

Human herpesvirus type 6 and human herpesvirus type 7 infections of the central nervous system.

S. Dewhurst, 2004, Herpes : the journal of the IHMF.

Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual

S. Dewhurst, D. Volsky, K. Sakai, 1988, Journal of virology.

Proviral DNA Cloning

J. Mullins, J. Overbaugh, S. Dewhurst, 1990 .

Nef gene evolution from a single transmitted strain in acute SIV infection

Pauline E. Chugh, A. Almudevar, D. O’Connor, 2009, Retrovirology.

Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini

S. Dewhurst, D. Gray, B. Thomson, 1994, Journal of virology.

Amplicons as vaccine vectors.

S. Dewhurst, C. Duke, K. Santos, 2006, Current gene therapy.

Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia1

G. Schifitto, S. Dewhurst, H. Gelbard, 2007, The Journal of Immunology.

Implications in HIV Type 1 Dementia and HIV-1 Tat Contributes to Inflammation: Functional Synergy between CD40 Ligand

G. Schifitto, S. Dewhurst, H. Gelbard, 2007 .

Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity

M. Reitz, P. Secchiero, V. Ruvolo, 1995, Journal of virology.

Influenza A Virus Attenuation by Codon Deoptimization of the NS Gene for Vaccine Development

Steven F. Baker, S. Dewhurst, D. Topham, 2014, Journal of Virology.

Engineered Fibronectin Type III Domain with a RGDWXE Sequence Binds with Enhanced Affinity and Specificity to Human αvβ3 Integrin

A. Koide, S. Koide, S. Dewhurst, 2003 .

Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6.

M. Mcdermott, S. Dewhurst, C. Hall, 2006, The Journal of infectious diseases.

Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7).

M. Mcdermott, S. Dewhurst, C. Hall, 2004, The Journal of pediatrics.

Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children.

M. Mcdermott, S. Dewhurst, C. Hall, 2004, The Journal of pediatrics.

Detection of Human Herpesvirus 6 by Reverse Transcription-PCR

S. Dewhurst, C. Hall, M. Caserta, 1999, Journal of Clinical Microbiology.

Expression of Human Immunodeficiency Virus Type 1 gp120 from Herpes Simplex Virus Type 1-Derived Amplicons Results in Potent, Specific, and Durable Cellular and Humoral Immune Responses

R. D. Wiley, H. Federoff, S. Dewhurst, 2002, Journal of Virology.

Humoral Immune Responses Potent , Specific , and Durable Cellular and Virus Type 1-Derived Amplicons Results in Virus Type 1 gp 120 from Herpes Simplex Expression of Human Immunodeficiency

R. D. Wiley, H. Federoff, S. Dewhurst, 2002 .

Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase*

R. Bambara, Baek Kim, S. Dewhurst, 2004, Journal of Biological Chemistry.

Mechanistic Understanding of an Altered Fidelity Simian Immunodeficiency Virus Reverse Transcriptase Mutation, V148I, Identified in a Pig-tailed Macaque*

R. Bambara, Baek Kim, S. Dewhurst, 2003, Journal of Biological Chemistry.

Enhancement of HIV-1 infectivity by simple, self-assembling modular peptides.

J. DiMaio, S. Dewhurst, B. Nilsson, 2011, Biophysical journal.

Methamphetamine causes sustained depression in cerebral blood flow

Changyong Feng, Berislav Zlokovic, Stephen Dewhurst, 2011, Brain Research.

Display of the HIV envelope protein at the yeast cell surface for immunogen development

M. Piepenbrink, S. Dewhurst, M. Dumont, 2018, PloS one.

Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation.

G. Schifitto, S. Dewhurst, S. Maggirwar, 2020, Blood advances.

ANTIBODIES TO HTLV-III/LAV AMONG ABORIGINAL AMAZONIAN INDIANS IN VENEZUELA

S. Dewhurst, D. Volsky, F. Sinangil, 1985, The Lancet.

Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV)

S. Dewhurst, D. Volsky, M. Stevenson, 1987, FEBS letters.

HIV‐1‐based defective lentiviral vectors efficiently transduce human monocytes‐derived macrophages and suppress replication of wild‐type HIV‐1

Stephen Dewhurst, Lingbing Zeng, Vicente Planelles, 2006, The journal of gene medicine.

A simple method for displaying recalcitrant proteins on the surface of bacteriophage lambda

S. Dewhurst, H. Lankes, B. Bradel-Tretheway, 2005, Nucleic acids research.

CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

H. Gendelman, S. Dewhurst, C. Gebhart, 2010, The Journal of Immunology.

Activation of nuclear factor kB in brains from children with HIV‐I encephalitis

S. Dewhurst, S. Dollard, L. Sharer, 1995 .

Inhibition of Mixed Lineage Kinase 3 Prevents HIV-1 Tat-Mediated Neurotoxicity and Monocyte Activation1

G. Schifitto, S. Dewhurst, H. Gelbard, 2006, The Journal of Immunology.

Monocyte Activation Prevents HIV-1 Tat-Mediated Neurotoxicity Inhibition of Mixed Lineage Kinase 3

G. Schifitto, S. Dewhurst, H. Gelbard, 2006 .

Neuroprotective Mechanisms of Lithium in Murine Human Immunodeficiency Virus-1 Encephalitis

H. Xiong, H. Gendelman, S. Dewhurst, 2005, The Journal of Neuroscience.

Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death

S. Dewhurst, N. Jin, S. Maggirwar, 2005, Neuropharmacology.

HIV‐1 Tat‐Mediated Activation of Glycogen Synthase Kinase‐3β Contributes to Tat‐Mediated Neurotoxicity

S. Dewhurst, H. Gelbard, S. Maggirwar, 1999, Journal of neurochemistry.

Proteasome inhibitors enhance bacteriophage lambda (λ) mediated gene transfer in mammalian cells

S. Dewhurst, Ketna Volcy, 2008, Virology.

Neuroprotective Activities of Sodium Valproate in a Murine Model of Human Immunodeficiency Virus-1 Encephalitis

H. Gendelman, S. Dewhurst, H. Gelbard, 2003, The Journal of Neuroscience.

HIV-1 Transactivator of Transcription Protein Induces Mitochondrial Hyperpolarization and Synaptic Stress Leading to Apoptosis1

S. Perry, S. Dewhurst, H. Gelbard, 2005, The Journal of Immunology.

Hydrophobic Nanoparticles Reduce the β-Sheet Content of SEVI Amyloid Fibrils and Inhibit SEVI-Enhanced HIV Infectivity.

C. Kubiak, S. Dewhurst, Jerry Yang, 2017, Langmuir : the ACS journal of surfaces and colloids.

Title Hydrophobic Nanoparticles Reduce the β-Sheet Content of SEVI Amyloid Fibrils and Inhibit SEVI-Enhanced HIV Infectivity Permalink

S. Dewhurst, Jerry Yang, Lauren R Brooks, 2017 .

A single amino acid substitution in PB1 of pandemic H1N1 with A/Ann Arbor/6/60 master donor virus mutations as a novel live-attenuated influenza virus vaccine

R. Albrecht, A. García-Sastre, S. Dewhurst, 2022, bioRxiv.

The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit

Baek Kim, S. Dewhurst, B. Bradel-Tretheway, 2008, The Journal of general virology.

Infection of Human Immunodeficiency Virus and Intracellular Viral Tat Protein Exert a Pro-survival Effect in a Human Microglial Cell Line

Pauline E. Chugh, Baek Kim, S. Dewhurst, 2006, Journal of Molecular Biology.

Selective Modification of Adenovirus Replication Can Be Achieved through Rational Mutagenesis of the Adenovirus Type 5 DNA Polymerase

Baek Kim, S. Dewhurst, C. Capella, 2012, Journal of Virology.

Biochemical Characterization of Enzyme Fidelity of Influenza A Virus RNA Polymerase Complex

Baek Kim, S. Dewhurst, B. Bradel-Tretheway, 2010, PloS one.

Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk?

Stephen Dewhurst, Seth W. Perry, Harris A. Gelbard, 2011, Journal of NeuroVirology.

Sequential Shrinkage and Swelling Underlie P2X7-Stimulated Lymphocyte Phosphatidylserine Exposure and Death1

C. Higgins, J. Elliott, S. Dewhurst, 2008, The Journal of Immunology.

Theoretical model of critical issues in informed consent in HIV vaccine trials

S. Dewhurst, J. McMahon, A. Alio, 2014, AIDS care.

Effects of codon-optimization on protein expression by the human herpesvirus 6 and 7 U51 open reading frame.

S. Dewhurst, B. Bradel-Tretheway, Z. Zhen, 2003, Journal of virological methods.

Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway.

S. Dewhurst, S. Ramirez, Tatiana M. Garcia, 2004, Brain research. Molecular brain research.

Nanoparticles decorated with viral antigens are more immunogenic at low surface density.

S. Dewhurst, A. Sant, C. Feng, 2017, Vaccine.

Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3.

D. Todd, S. Dewhurst, H. Gelbard, 2013, Journal of medicinal chemistry.

Natural Seminal Amyloids as Targets for Development of Synthetic Inhibitors of HIV Transmission.

S. Dewhurst, Jerry Yang, Daniel A. Sheik, 2017, Accounts of chemical research.

Fluorescence detection of cationic amyloid fibrils in human semen.

J. DiMaio, S. Dewhurst, B. Nilsson, 2013, Bioorganic & medicinal chemistry letters.

The semen enhancer of viral infection ( SEVI ) binds bacteria , enhances 1 bacterial phagocytosis by macrophages , and can protect against 2 vaginal infection by a sexually transmitted bacterial pathogen

Jharon N. Silva, S. Dewhurst, C. Feng, 2013 .

Seminal Plasma Accelerates Semen-derived Enhancer of Viral Infection (SEVI) Fibril Formation by the Prostatic Acid Phosphatase (PAP248–286) Peptide*

J. DiMaio, S. Dewhurst, B. Nilsson, 2012, The Journal of Biological Chemistry.

Comprehensive Proteomic Analysis of Influenza Virus Polymerase Complex Reveals a Novel Association with Mitochondrial Proteins and RNA Polymerase Accessory Factors

M. Katze, S. Dewhurst, B. Bradel-Tretheway, 2011, Journal of Virology.

Cellular mono(ADP‐ribosyl) transferase inhibits protein synthesis

S. Dewhurst, W. Iglewski, 1991, FEBS letters.

Anti-idiotypic monobodies derived from a fibronectin scaffold.

S. Dewhurst, I. Sanz, William Domm, 2013, Biochemistry.

Postinoculation PMPA Treatment, but Not Preinoculation Immunomodulatory Therapy, Protects against Development of Acute Disease Induced by the Unique Simian Immunodeficiency Virus SIVsmmPBj

H. McClure, S. Dewhurst, Daniel C. Anderson, 1999, Journal of Virology.

Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment

H. Gendelman, G. Schifitto, J. Zhong, 2009, Journal of NeuroVirology.

A Mutated PB1 Residue 319 Synergizes with the PB2 N265S Mutation of the Live Attenuated Influenza Vaccine to Convey Temperature Sensitivity

Baek Kim, S. Dewhurst, D. Levenson, 2020, Viruses.

Leading to Apoptosis Hyperpolarization and Synaptic Stress Protein Induces Mitochondrial HIV-1 Transactivator of Transcription

S. Perry, S. Dewhurst, H. Gelbard, 2005 .

Biochemical Impact of the Host Adaptation-associated PB2 E627K Mutation on the Temperature-dependent RNA Synthesis Kinetics of Influenza A Virus Polymerase Complex*

Baek Kim, S. Dewhurst, T. Takimoto, 2011, The Journal of Biological Chemistry.

HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

E. Masliah, K. L. de Mesy Bentley, S. Perry, 2008, PloS one.

Functional Interplay Between Nuclear Factor‐κB and c‐Jun Integrated by Coactivator p300 Determines the Survival of Nerve Growth Factor‐Dependent PC12 Cells

S. Dewhurst, H. Gelbard, S. Maggirwar, 2000, Journal of neurochemistry.

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines

Baek Kim, S. Dewhurst, D. Topham, 2019, Viruses.

Effect of Dolutegravir and Sertraline on the Blood Brain Barrier (BBB)

G. Schifitto, S. Dewhurst, R. Aalinkeel, 2020, Journal of Neuroimmune Pharmacology.

Effect of Dolutegravir and Sertraline on the Blood Brain Barrier (BBB)

G. Schifitto, S. Dewhurst, R. Aalinkeel, 2020, Journal of Neuroimmune Pharmacology.

Directional histogram ratio at random probes: A local thresholding criterion for capillary images

Hulin Wu, Na Lu, Hongyu Miao, 2013, Pattern Recognit..

Antibodies to HTLV-III/LAV in Venezuelan patients with acute malarial infections.

S. Dewhurst, D. Volsky, F. Sinangil, 1986, The New England journal of medicine.

Poor Aerobic Fitness May Contribute to Cognitive Decline in HIV-infected Older Adults.

Hongmei Yang, M. Mapstone, S. Dewhurst, 2013, Aging and disease.

Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection

D. Mathews, T. Mariani, J. Thakar, 2023, mBio.

Neuroprotective Activities of CEP-1347 in Models of NeuroAIDS

H. Gendelman, G. Schifitto, S. Dewhurst, 2009, The Journal of Immunology.

HIV-1 Tat-Induced Microgliosis and Synaptic Damage via Interactions between Peripheral and Central Myeloid Cells

Shao-Ming Lu, Stephen Dewhurst, Harris A. Gelbard, 2011, PloS one.

Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism.

S. Dewhurst, H. Gelbard, S. Maggirwar, 2001, Journal of neurochemistry.

HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism.

L. Epstein, S. Dewhurst, H. Gelbard, 1998, The Journal of biological chemistry.

Glycogen Synthase Kinase 3 Beta (GSK-3β) as a Therapeutic Target in NeuroAIDS

H. Gendelman, G. Schifitto, S. Dewhurst, 2007, Journal of Neuroimmune Pharmacology.

Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons.

S. Dewhurst, H. Gelbard, M. Potash, 2006, The European journal of neuroscience.

High prevalence and high titers of LAV/HTLV-III antibodies in healthy hemophiliacs in the midwestern United States.

S. Dewhurst, D. Volsky, J. Goldsmith, 1986, The American journal of medicine.

Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5

Jharon N. Silva, K. Kasischke, S. Dewhurst, 2012, Journal of Neuroinflammation.

Expression of pro‐ and anti‐apoptosis gene products in brains from paediatric patients with HIV‐1 encephalitis

H. Gendelman, John Calvin Reed, S. Krajewski, 1997, Neuropathology and applied neurobiology.

Enhanced transduction of dendritic cells by FcγRI‐targeted adenovirus vectors

S. Dewhurst, C. Maguire, Ramil E. Sapinoro, 2007 .

Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells

T. Mariani, J. Thakar, M. Pavelka, 2023, PloS one.

SIVsmm infection of macaque and mangabey monkeys: correlation between in vivo and in vitro properties of different isolates.

J. Mullins, P. Fultz, H. McClure, 1990, Developments in biological standardization.

Utilization and Impact of Symptomatic and Exposure SARS-CoV-2 Testing in K-12 Schools.

M. Brookhart, M. Zand, S. Dewhurst, 2023, Pediatrics.

Antibodies to acquired immune deficiency syndrome (AIDS)-associated virus (HTLV-III/LAV) in Venezuelan populations.

S. Dewhurst, D. Volsky, F. Sinangil, 1986, AIDS research.

Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence

Jharon N. Silva, K. Kasischke, S. Dewhurst, 2012, Journal of visualized experiments : JoVE.

Direct sequence analysis of human herpesvirus 6 (HHV-6) sequences from infants and comparison of HHV-6 sequences from mother/infant pairs.

S. Dewhurst, C. Hall, S. Gummuluru, 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

SIVsmmPBj14 induces expression of a mucosal integrin on macaque lymphocytes.

S. Dewhurst, S. Gummuluru, B. Seshi, 1996, Virology.

Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming.

R. D. Wiley, H. Federoff, S. Dewhurst, 2003, Vaccine.

Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis.

L. Epstein, S. Dewhurst, H. Gelbard, 1995, Neuropathology and applied neurobiology.

Endogenous tumor necrosis factor-alpha contributes to lymphoproliferation induced by simian immunodeficiency virus variant, SIVsmmPBj14.

S. Dewhurst, F. Novembre, S. Hodge, 1998, Immunology letters.

Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients

H. Gendelman, G. Schifitto, S. Dewhurst, 2013, Journal of NeuroVirology.

A Single Mutation at PB1 Residue 319 Dramatically Increases the Safety of PR8 Live Attenuated Influenza Vaccine in a Murine Model without Compromising Vaccine Efficacy

S. Dewhurst, Andrew Cox, 2015, Journal of Virology.

Semen-Derived Enhancer of Viral Infection (SEVI) Binds Bacteria, Enhances Bacterial Phagocytosis by Macrophages, and Can Protect against Vaginal Infection by a Sexually Transmitted Bacterial Pathogen

Jharon N. Silva, S. Dewhurst, C. Feng, 2013, Antimicrobial Agents and Chemotherapy.

Development of a New, More Effective Live-Attenuated Influenza Vaccine: An Essential Platform for Future Pandemic Protection

S. Dewhurst, 2019 .

Testing for Antibodies to AIDS-Associated Retrovirus (HTLVWLAV) by Indirect Fixed Cell

S. Dewhurst, D. Volsky, F. Sinangil, 2005 .