A. Andreadis

发表

Tau is a candidate gene for chromosome 17 frontotemporal dementia

G. Schellenberg, E. Wijsman, T. Bird, 1998, Annals of neurology.

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

Ronald C. Petersen, Frank Owen, Stanley Fahn, 1998, Nature.

Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes.

B. Nadal-Ginard, A. Andreadis, R. Breitbart, 1987, Annual review of biochemistry.

Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21–22

M. Farrer, S. Lincoln, J. Hardy, 1997, Annals of neurology.

Tau gene polymorphisms and apolipoprotein E epsilon4 may interact to increase risk for Alzheimer's disease.

B. Winblad, L. Fratiglioni, M. Viitanen, 1999, Neuroscience letters.

A τ Promoter Region Without Neuronal Specificity

K. Kosik, B. Wagner, A. Andreadis, 1996 .

Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21.

L. Lannfelt, H. Basun, A. Andreadis, 1997, American journal of medical genetics.

SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations

A. Andreadis, Lei Gao, Junning Wang, 2007, Molecular and Cellular Neuroscience.

Tau gene polymorphisms and apolipoprotein E ε4 may interact to increase risk for Alzheimer’s disease

B. Winblad, L. Fratiglioni, M. Viitanen, 1999, Neuroscience Letters.

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

A. Andreadis, N. Lapointe, G. Pigino, 2012, Neurobiology of Aging.

Tau isoforms which contain the domain encoded by exon 6 and their role in neurite elongation

A. Andreadis, M. Leski, M. Luo, 2004, Journal of cellular biochemistry.

A tau promoter region without neuronal specificity.

K. Kosik, B. Wagner, A. Andreadis, 1996, Journal of neurochemistry.

Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy

L. Thal, R. Katzman., E. Masliah, 1998, Neuroscience Letters.

The expression of sarcomeric muscle-specific contractile protein genes in BC3H1 cells: BC3H1 cells resemble skeletal myoblasts that are defective for commitment to terminal differentiation

C. W. Smith, B. Nadal-Ginard, S. Izumo, 1989, The Journal of cell biology.

Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine

P. Schimmel, A. Andreadis, G. Kohlhaw, 1982, Cell.

An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia.

S. Stamm, A. Andreadis, Yan Wang, 2011, Gene.

Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons.

K. Kosik, A. Andreadis, J. Broderick, 1995, Nucleic acids research.

Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human‐specific allele influences Abl phosphorylation

C. Conrad, A. Andreadis, Yan Wang, 2011, Journal of cellular biochemistry.

Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro.

A. Andreadis, N. Lapointe, P. Horowitz, 2009, Biochemistry.

Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases.

A. Andreadis, 2005, Biochimica et biophysica acta.

The exon trapping assay partly discriminates against alternatively spliced exons.

K. Kosik, A. Andreadis, P. Watkins, 1993, Nucleic acids research.

Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease

G. V. Van Hoesen, R. Thangavel, A. Andreadis, 2004, The Journal of Neuroscience.

Generation of protein isoform diversity by alternative splicing: mechanistic and biological implications.

B. Nadal-Ginard, A. Andreadis, M. Gallego, 1987, Annual review of cell biology.

Alternative Splicing: Mechanistic and Biological Implications of Generating Multiple Proteins from a Single Gene

B. Nadal-Ginard, A. Andreadis, M. Gallego, 1987 .

Structure and novel exons of the human tau gene.

K. Kosik, A. Andreadis, W. M. Brown, 1992, Biochemistry.

A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse

U. Dräger, A. Andreadis, P. McCaffery, 2000, Mechanisms of Development.

Genetic evidence for the involvement of τ in progressive supranuclear palsy

L. Thal, J. Trojanowski, R. Katzman., 1997, Annals of neurology.

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

S. Stamm, R. Lafyatis, A. Andreadis, 2004, Journal of neurochemistry.

PROMOTER SELECTION AND ALTERNATIVE PRE-mRNA SPLICING ARE USED TO GENERATE COMPLEX CONTRACTILE PROTEIN PHENOTYPES

B. Nadal-Ginard, A. Andreadis, R. Breitbart, 1987 .

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2‐BETA1 changes in sporadic Alzheimer's disease

K. Jellinger, D. Rujescu, H. Möller, 2006, Journal of neurochemistry.

The STAR/GSG Family Protein rSLM-2 Regulates the Selection of Alternative Splice Sites*

A. Hartmann, S. Stamm, A. Andreadis, 2001, The Journal of Biological Chemistry.

Expression profiles of genes in DJ-1-knockdown and L166P DJ-1 mutant cells

K. Takahashi-Niki, T. Taira, S. Iguchi-Ariga, 2005, Neuroscience Letters.

The role and evolutionary development of retinoic-acid signalling in the eye

U. Dräger, A. Andreadis, P. McCaffery, 2000 .

Saitohin, Which Is Nested in the tau Locus and Confers Allele-specific Susceptibility to Several Neurodegenerative Diseases, Interacts with Peroxiredoxin 6*

C. Conrad, A. Andreadis, S. Tse, 2005, Journal of Biological Chemistry.

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

J. Julien, L. Engle, R. Nixon, 2002, The Journal of cell biology.

Misregulation of tau alternative splicing in neurodegeneration and dementia.

A. Andreadis, 2006, Progress in molecular and subcellular biology.

Tau Exons 2 and 10, Which Are Misregulated in Neurodegenerative Diseases, Are Partly Regulated by Silencers Which Bind a SRp30c·SRp55 Complex That Either Recruits or Antagonizes htra2β1*

S. Stamm, R. Lafyatis, A. Andreadis, 2005, Journal of Biological Chemistry.

Modulation of the membrane-binding domain of tau protein: splicing regulation of exon 2.

A. Andreadis, M. Arikan, Karen Li, 2003, Brain research. Molecular brain research.

Modulation of the membrane-binding projection domain of tau protein: splicing regulation of exon 3.

S. Stamm, G. Screaton, R. Lafyatis, 2002, Brain research. Molecular brain research.

C 6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1

Manjula., Sunkara, S. Stamm, 2019 .

Tau splicing and the intricacies of dementia

A. Andreadis, 2012, Journal of Cellular Physiology.

DARPP-32 binds to tra2-beta1 and influences alternative splicing.

J. Girault, S. Stamm, C. Becker, 2010, Biochimica et biophysica acta.

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17.

D. Geschwind, G. Schellenberg, J. Trojanowski, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The splicing determinants of a regulated exon in the axonal MAP tau reside within the exon and in its upstream intron.

G. Screaton, A. Andreadis, J. Memmott, 2000, Brain research. Molecular brain research.

Complex Regulation of Tau Exon 10, Whose Missplicing Causes Frontotemporal Dementia

S. Stamm, G. Screaton, R. Lafyatis, 2000, Journal of neurochemistry.

Regulation of Alternative Splicing of Human Tau Exon 10 by Phosphorylation of Splicing Factors

D. Rujescu, A. Hartmann, S. Stamm, 2001, Molecular and Cellular Neuroscience.

Novel isoforms of tau that lack the microtubule‐binding domain

A. Andreadis, J. Memmott, S. Tse, 2004, Journal of neurochemistry.

Splicing of a Regulated Exon Reveals Additional Complexity in the Axonal Microtubule‐Associated Protein Tau

A. Andreadis, M. Wei, 1998, Journal of neurochemistry.

Heterogeneous nuclear ribonucleoprotein E3 modestly activates splicing of tau exon 10 via its proximal downstream intron, a hotspot for frontotemporal dementia mutations.

A. Andreadis, Yan Wang, S. Tse, 2010, Gene.

Transgenic Mouse Model of Tauopathies with Glial Pathology and Nervous System Degeneration

J. Trojanowski, V. Lee, M. Higuchi, 2002, Neuron.

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

A. Andreadis, N. Lapointe, G. Pigino, 2011, The Journal of Neuroscience.

Tau exon 6 is regulated by an intricate interplay of trans factors and cis elements, including multiple branch points

A. Andreadis, S. Tse, Junning Wang, 2007, Journal of neurochemistry.

Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product.

P. Schimmel, A. Andreadis, M. Hermodson, 1984, The Journal of biological chemistry.

Transcriptional regulation of the mouse microtubule-associated protein tau.

A. Andreadis, K. L. Tucker, Lei Gao, 2005, Biochimica et biophysica acta.

Heterogeneous nuclear ribonucleoprotein E2 binds to tau exon 10 and moderately activates its splicing.

A. Andreadis, J. Broderick, Junning Wang, 2004, Gene.

Tau Protects Microtubules in the Axon from Severing by Katanin

L. Qiang, A. Andreadis, P. Baas, 2006, The Journal of Neuroscience.

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport Through a Tau-Dependent Mechanism Involving Activation of Axonal

A. Andreadis, N. Lapointe, G. Pigino, 2012 .

Brain Expression of Presenilins in Sporadic and Early-onset, Familial Alzheimer’s Disease

P. Fraser, T. Bird, C. Hulette, 2000, Molecular medicine.

Brain-specific change in alternative splicing of Tau exon 6 in myotonic dystrophy type 1.

T. Cooper, L. Buée, N. Sergeant, 2006, Biochimica et biophysica acta.

ETR‐3 represses Tau exons 2/3 inclusion, a splicing event abnormally enhanced in myotonic dystrophy type I

A. Delacourte, L. Buée, N. Sergeant, 2006, Journal of neuroscience research.

Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain.

S. Stamm, A. Andreadis, J. Broderick, 2005, Gene.

C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1

S. Stamm, M. Bollen, J. Adams, 2011, Nucleic acids research.

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

J. Julien, L. Engle, R. Nixon, 2002, The Journal of cell biology.

Short communication Transcriptional regulation of the mouse microtubule-associated protein tau

A. Andreadis, Lei Gao, Kerry L. Tucker, 2005 .