P. Horne

发表

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.

P. S. St George-Hyslop, D. Westaway, P. Fraser, 2000, Nature.

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695*

S. Turner, D. Westaway, G. Carlson, 2001, The Journal of Biological Chemistry.

In vivo reduction of amyloid-beta by a mutant copper transporter.

P. S. St George-Hyslop, D. Westaway, G. Carlson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

An Aggregate-Inducing Peripherin Isoform Generated through Intron Retention Is Upregulated in Amyotrophic Lateral Sclerosis and Associated with Disease Pathology

M. Strong, Yuxin Fan, P. Horne, 2008, The Journal of Neuroscience.

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS

A. Chakrabartty, P. Horne, D. Cleveland, 2007, Nature Medicine.

Lack of evidence of monomer/misfolded superoxide dismutase‐1 in sporadic amyotrophic lateral sclerosis

E. Rogaeva, E. Pioro, M. Strong, 2009, Annals of neurology.

Aβ vaccination of a genetic model of Alzheimer's disease

D. Westaway, P. Fraser, P. George-Hyslop, 2003 .

Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis

D. Westaway, P. Fraser, P. George-Hyslop, 2002, Nature Medicine.

Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation.

P. S. St George-Hyslop, D. Westaway, G. Carlson, 2006, The American journal of pathology.

Evidence That TDP-43 is Not the Major Ubiquitinated Target Within the Pathological Inclusions of Amyotrophic Lateral Sclerosis

L. Zinman, P. Horne, J. Bilbao, 2007, Journal of neuropathology and experimental neurology.

Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS

E. Pioro, M. Strong, P. Horne, 2007, Neuroscience Letters.

Dissociated phenotypes in presenilin transgenic mice define functionally distinct γ-secretases

R. Rozmahel, C. Ebeling, D. Westaway, 2005 .

In vivo reduction of amyloid-β by a mutant copper transporter

D. Westaway, G. Carlson, P. George-Hyslop, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

David S. Park, Suneil K. Kalia, H. Anisman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections

Bob Strome, Gerold Schmitt-Ulms, Patrick Horne, 2007, The EMBO journal.

The in Vivo Brain Interactome of the Amyloid Precursor Protein*S

P. S. St George-Hyslop, D. Westaway, P. Fraser, 2008, Molecular & Cellular Proteomics.

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

Ralph A. Nixon, Paul M. Mathews, Patrick Horne, 2000, Nature.

Amyloid β and impairment in multiple memory systems in older transgenic APP TgCRND8 mice

C. Eckman, C. Janus, P. Horne, 2009, Genes, brain, and behavior.

Mouse models of Alzheimer's disease: The long and filamentous road

D. Westaway, C. Janus, P. Horne, 2003, Neurological research.

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

P. S. St George-Hyslop, D. Westaway, P. Fraser, 2002, Nature medicine.

Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.

R. Rozmahel, P. S. St George-Hyslop, C. Ebeling, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A b peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer ' s disease

D. Westaway, P. Fraser, P. George-Hyslop, 2022 .

Assembly of Alzheimer's amyloid-beta fibrils and approaches for therapeutic intervention.

D. Westaway, L. Serpell, P. Fraser, 2001, Amyloid: Journal of Protein Folding Disorders.

The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections

D. Westaway, G. Carlson, Rebecca Young, 2007, The EMBO journal.

An Aggregate-Inducing Peripherin Isoform Generated through Intron Retention Is Upregulated in Amyotrophic Lateral Sclerosis and Associated with Disease Pathology

M. Strong, Yuxin Fan, P. Horne, 2008, Journal of Neuroscience.

Lack of evidence of monomer/misfolded superoxide dismutase‐1 in sporadic amyotrophic lateral sclerosis

E. Rogaeva, E. Pioro, M. Strong, 2009, Annals of neurology.