S. Allan

N. Rothwell, M. Schwaninger, D. Vivien, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The interleukin-1 system: an attractive and viable therapeutic target in neurodegenerative disease.

S. Allan, E. Pinteaux, 2003, Current drug targets. CNS and neurological disorders.

Neuroinflammation in Parkinson’s patients and MPTP-treated mice is not restricted to the nigrostriatal system: Microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb

J. Relton, P. Cras, J. Bol, 2007, Experimental Gerontology.

Occult Cerebrovascular Disease and Late-Onset Epilepsy: Could Loss of Neurovascular Unit Integrity Be a Viable Model?

S. Allan, L. Parkes, H. Emsley, 2011, Cardiovascular psychiatry and neurology.

Interleukin‐1 as a pharmacological target in acute brain injury

N. Rothwell, D. Brough, S. Allan, 2015, Experimental physiology.

Value of dynamic clinical and biomarker data for mortality risk prediction in COVID-19: a multicentre retrospective cohort study

L. Bernardinelli, D. Brough, H. Patel, 2020, BMJ Open.

A luminescent probe containing a tuftsin targeting vector coupled to a terbium complex.

R. J. Aarons, R. Kauppinen, N. Spencer, 2006, Chemical communications.

Endogenous Oils Derived From Human Adipocytes Are Potent Adjuvants That Promote IL-1α–Dependent Inflammation

K. H. Mok, H. Roche, S. Allan, 2014, Diabetes.

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

D. Brough, S. Allan, E. Karran, 2018, Scientific Reports.

Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis

I. Lizasoain, N. Rothwell, E. Lo, 2016, Stroke.

Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathy

A. Simpson, M. Menon, S. Allan, 2020, medRxiv.

Regenerative Potential of Hydrogels for Intracerebral Hemorrhage: Lessons from Ischemic Stroke and Traumatic Brain Injury Research

J. M. Thomas, S. Allan, C. Lawrence, 2021, Advanced healthcare materials.

A Rapid and Transient Peripheral Inflammatory Response Precedes Brain Inflammation after Experimental Stroke

B. McColl, N. Rothwell, S. Allan, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation

N. Rothwell, S. Allan, Á. Dénes, 2010, Brain, Behavior, and Immunity.

Characterisation of microvessel blood velocity and segment length in the brain using multi-diffusion-time diffusion-weighted MRI

G. Parker, S. Allan, L. Parkes, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Influence of metabolic syndrome on post-stroke outcome, angiogenesis and vascular function in old rats determined by dynamic contrast enhanced MRI

I. Lizasoain, M. A. Moro, M. Ledesma-Carbayo, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice

S. Allan, C. Lawrence, M. Haley, 2019, Translational Stroke Research.

The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications.

N. Rothwell, S. Allan, S. Toulmond, 1997, The Journal of clinical investigation.

Late-Onset Epilepsy and Occult Cerebrovascular Disease

S. Allan, L. Parkes, M. Hanby, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro

N. Rothwell, S. Allan, C. Kielty, 2017, Stem Cell Research & Therapy.

Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways.

B. McColl, N. Rothwell, S. Allan, 2010, Current neurovascular research.

Systematic Review and Meta-Analysis of the Efficacy of Statins in Experimental Stroke

S. Allan, A. Vail, Craig J. Smith, 2012, International journal of stroke : official journal of the International Stroke Society.

Interleukin-1 receptor antagonist in animal models of stroke: a fair summing up?

B. McColl, A. Parry-Jones, S. Allan, 2010, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

ADAMTS-9 expression is up-regulated following transient middle cerebral artery occlusion (tMCAo) in the rat

S. Allan, M. Woodroofe, D. Buttle, 2009, Neuroscience Letters.

Improved reperfusion following alternative surgical approach for experimental stroke in mice.

S. Allan, C. Gibson, R. Wong, 2020, F1000Research.

Improved reperfusion following alternative surgical approach for experimental stroke in mice

S. Allan, C. Gibson, R. Wong, 2020, F1000Research.

Systemic inflammation and stroke: aetiology, pathology and targets for therapy.

B. McColl, N. Rothwell, S. Allan, 2007, Biochemical Society transactions.

Stroke: The past, present and future

S. Allan, I. Macrae, 2018, Brain and neuroscience advances.

The Acute-Phase Protein PTX3 is an Essential Mediator of Glial Scar Formation and Resolution of Brain Edema after Ischemic Injury

N. Rothwell, C. Garlanda, S. Allan, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Using Zebrafish Larvae to Study the Pathological Consequences of Hemorrhagic Stroke.

A. Parry-Jones, S. Allan, P. Kasher, 2019, Journal of visualized experiments : JoVE.

Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer’s disease

S. Love, S. Allan, D. Boche, 2021, Brain : a journal of neurology.

Studies on inflammation and stroke provide clues to pathomechanism of central nervous system involvement in COVID-19.

T. Hortobágyi, S. Allan, Á. Dénes, 2020, Free neuropathology.

Systematic review: Association between circulating microRNA expression & stroke

J. M. Thomas, S. Allan, L. Work, 2022, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer’s disease

M. Nelson, S. Allan, D. Hill-Eubanks, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Cardiovascular comorbidities, inflammation, and cerebral small vessel disease

S. Allan, A. Greenstein, Craig J. Smith, 2021 .

Platelet interleukin-1alpha drives cerebrovascular inflammation.

B. McColl, N. Rothwell, S. Allan, 2010, Blood.

Tuftsin derivatives of FITC, Tb-DOTA or Gd-DOTA as potential macrophage-specific imaging biomarkers.

R. Kauppinen, S. Allan, S. Faulkner, 2010, Contrast media & molecular imaging.

Emerging roles of the acute phase protein pentraxin-3 during central nervous system disorders

S. Allan, Á. Dénes, E. Pinteaux, 2016, Journal of Neuroimmunology.

Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease

A. Verkhratsky, S. Allan, C. Lawrence, 2012, Neurobiology of Aging.

Interleukin‐1‐induced neurotoxicity is mediated by glia and requires caspase activation and free radical release

N. Rothwell, S. Allan, R. Gibson, 2006, Journal of neurochemistry.

Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice

B. McColl, N. Rothwell, S. Allan, 2008, The Journal of Neuroscience.

Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα

N. Rothwell, B. Nieswandt, S. Allan, 2014, Annals of neurology.

Endotoxin , TNF , and ILI decrease cholesterol 7 a-hydroxylase mRNA levels and activity

Kenneth, C. Grunfeld, S. Allan, 2002 .

Acute high-fat feeding leads to disruptions in glucose homeostasis and worsens stroke outcome

I. Schiessl, S. Allan, C. Lawrence, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage*

D. Brough, S. Allan, M. Edye, 2015, The Journal of Biological Chemistry.

Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice

N. Rothwell, S. Allan, Á. Dénes, 2013, Disease Models & Mechanisms.

Neuroinflammatory changes in cerebral ischaemia and other central nervous system (CNS) diseases are driven by both activated glia and peripheral immune cells (Ransohoff and Brown, 2012; Denes

N. Rothwell, S. Allan, Á. Dénes, 2013 .

Interleukin-1 in Stroke: From Bench to Bedside.

N. Rothwell, A. Parry-Jones, S. Allan, 2016, Stroke.

Chitinase-like proteins promote IL-17-mediated neutrophilia in a trade-off between nematode killing and host damage

R. Maizels, B. Stockinger, S. Allan, 2014, Nature Immunology.

Surgical manipulation compromises leukocyte mobilization responses and inflammation after experimental cerebral ischemia in mice

N. Rothwell, S. Allan, C. Drake, 2014, Front. Neurosci..

Delayed Administration of Interleukin-1 Receptor Antagonist Reduces Ischemic Brain Damage and Inflammation in Comorbid Rats

B. McColl, N. Rothwell, S. Allan, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1.

N. Rothwell, A. A. Parsons, D. Harrison, 2001, Brain research. Molecular brain research.

Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome

D. Brough, S. Allan, Judith E. Allen, 2019, Stroke.

Caspase-1-independent Pathway Interleukin-1 Secretion via a Molecular Pattern ( DAMP )-induced Acidosis Drives Damage-associated Immunology :

G. López-Castejón, D. Brough, S. Allan, 2013 .

IL‐1α and inflammasome‐independent IL‐1β promote neutrophil infiltration following alum vaccination

S. Allan, E. Lavelle, Claire H A Hearnden, 2016, The FEBS journal.

ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes

S. Allan, M. Woodroofe, D. Buttle, 2006, Brain Research.

Targeting the IL33–NLRP3 axis improves therapy for experimental cerebral malaria

A. Craig, D. Brough, D. Golenbock, 2018, Proceedings of the National Academy of Sciences.

IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells

N. Rothwell, S. Allan, C. Lawrence, 2003, Journal of Neuroimmunology.

Platelet interleukin-1 (cid:1) drives cerebrovascular inﬂammation

B. McColl, N. Rothwell, S. Allan, 2010 .

Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat.

N. Rothwell, S. Allan, G. Luheshi, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Selective brain entry of lipid nanoparticles in haemorrhagic stroke is linked to biphasic blood-brain barrier disruption

A. Parry-Jones, S. Allan, Kostas Kostarelos, 2022, Theranostics.

Peripheral administration of interleukin-1β exacerbates ischaemic brain damage after transient focal ischaemia in mice

B. McColl, N. Rothwell, S. Allan, 2005 .

Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage.

A. Parry-Jones, S. Allan, A. Hurlstone, 2018, F1000Research.

Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage

A. Parry-Jones, S. Allan, A. Hurlstone, 2018, F1000Research.

Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti- microbial defence [version 2; peer review: 2 approved]

B. McColl, S. Allan, Craig J. Smith, 2021 .

Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence.

B. McColl, S. Allan, Craig J. Smith, 2019, F1000Research.

Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence

B. McColl, S. Allan, Craig J. Smith, 2019, bioRxiv.

Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo

N. Rothwell, S. Allan, M. Craighead, 2000, Brain Research.

Isolation and Cultivation of Primary Brain Endothelial Cells from Adult Mice.

T. Walther, M. Schwaninger, S. Allan, 2017, Bio-protocol.

Pentraxin 3 regulates neutrophil infiltration to the brain during neuroinflammation

S. Allan, E. Pinteaux, R. Wong, 2019, AMRC open research.

Pragmatic target discovery from novel gene to functionally defined drug target: the interleukin-1 story.

S. Allan, 2005, Methods in molecular medicine.

Anti-inflammatory modulators in stroke

D. Anthony, S. Allan, M. O'Neill, 2004 .

Generation of Human Mesenchymal Stem Cell 3D Spheroids Using Low-binding Plates.

S. Allan, E. Pinteaux, S. Cain, 2018, Bio-protocol.

Systemic innate myeloid responses to acute ischaemic and haemorrhagic stroke

S. Allan, J. Grainger, Craig J. Smith, 2022, Seminars in Immunopathology.

Decondensed DNA Release of Proteases Associated with Triggers Rapid Neurotoxicity through Neutrophil Cerebrovascular Transmigration

N. Rothwell, S. Allan, M. Monestier, 2012 .

Circulating Cytokines and Alarmins Associated with Placental Inflammation in High-Risk Pregnancies

C. Sibley, S. Allan, A. Heazell, 2014, American journal of reproductive immunology.

Interleukin‐1 in the Brain

S. Allan, H. Boutin, H. C. Patel, 2003 .

Interleukin-1 in the brain: mechanisms of action in acute neurodegeneration.

S. Allan, H. Boutin, H. C. Patel, 2003, Annals of the New York Academy of Sciences.

Do Concentration or Activity of Selenoproteins Change in Acute Stroke Patients? A Systematic Review and Meta-Analyses

S. Allan, S. Rhodes, J. Grainger, 2022, Cerebrovascular Diseases.

Letter by McColl et al regarding article, "influenza virus infection aggravates stroke outcome".

B. McColl, S. Allan, Á. Dénes, 2011, Stroke.

SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke): A Randomized Controlled Phase 2 Trial

N. Rothwell, A. Parry-Jones, S. Allan, 2018, Stroke.

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Eric E. Smith, J. Schneider, A. Toga, 2019, Alzheimer's & Dementia.

Interleukin-1β and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes

N. Rothwell, S. Allan, C. Lawrence, 1998, Molecular Psychiatry.

Characterization of a conditional interleukin‐1 receptor 1 mouse mutant using the Cre/LoxP system

N. Rothwell, A. Waisman, Werner Müller, 2016, European journal of immunology.

The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications.

N. Rothwell, S. Allan, S. Toulmond, 1997, The Journal of clinical investigation.

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia

N. Rothwell, S. Allan, H. Boutin, 2017, Brain, Behavior, and Immunity.

Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis

B. McColl, N. Rothwell, D. Crossman, 2012, Journal of the American Heart Association.

A novel genotyping method to determine copy number in a mouse line commonly used for inducible transgene expression in brain and spinal cord

S. Rollinson, S. Pickering-Brown, S. Allan, 2020, F1000Research.

An Endovascular Perforation Model of Subarachnoid Haemorrhage in Rat Produces Heterogeneous Infarcts that Increase with Blood Load

N. Rothwell, S. Allan, A. Greenhalgh, 2012, Translational Stroke Research.

Treatment with IgM‐enriched intravenous immunoglobulins enhances clearance of stroke‐associated bacterial lung infection

B. McColl, S. Allan, J. Grainger, 2022 .

Proliferating Resident Microglia after Focal Cerebral Ischaemia in Mice

R. Kauppinen, B. McColl, S. Allan, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Re-directing nanomedicines to the spleen: A potential technology for peripheral immunomodulation.

S. Allan, Z. Al-Ahmady, Satinderdeep Kaur, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Interleukin-1 and neuronal injury

N. Rothwell, S. Allan, P. Tyrrell, 2005, Nature Reviews Immunology.

Boron-Based Inhibitors of the NLRP3 Inflammasome

N. Rothwell, D. Brough, S. Allan, 2017, Cell chemical biology.

A quantitative brain map of experimental cerebral malaria pathology

A. Craig, J. Schwartz, D. Milner, 2017, PLoS pathogens.

Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms

B. McColl, N. Rothwell, S. Allan, 2007, The Journal of Neuroscience.

Cytokines and acute neurodegeneration

N. Rothwell, S. Allan, 2001, Nature Reviews Neuroscience.

High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology

S. Allan, C. Lawrence, E. Knight, 2014, Neurobiology of Aging.

Mechanisms of Comorbidities Associated With the Metabolic Syndrome: Insights from the JCR:LA-cp Corpulent Rat Strain

W. Pierce, S. Allan, S. Proctor, 2016, Front. Nutr..

Beyond Antoni: A Surgeon's Guide to the Vestibular Schwannoma Microenvironment

D. Brough, S. Allan, S. Rutherford, 2020, Journal of Neurological Surgery Part B: Skull Base.

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

A. Verkhratsky, Jose Julio Rodriguez, F. LaFerla, 2008, PloS one.

Brevican and phosphacan expression and localization following transient middle cerebral artery occlusion in the rat.

B. Sharrack, S. Allan, M. Woodroofe, 2007, Biochemical Society transactions.

Microglia and Macrophages Differentially Modulate Cell Death After Brain Injury Caused by Oxygen-Glucose Deprivation in Organotypic Brain Slices

Sylvie Girard, David Brough, G. López-Castejón, 2013, Glia.

In vivo methods for imaging blood–brain barrier function and dysfunction

I. Schiessl, R. Hinz, S. Allan, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons

N. Rothwell, A. Waisman, M. Schwaninger, 2019, Brain, Behavior, and Immunity.

A brain in flame; do inflammasomes and pyroptosis influence stroke pathology?

S. Allan, E. Lemarchand, Jack Barrington, 2017, Brain pathology.

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

D. Brough, P. Paszek, J. Bagnall, 2016, Nature Communications.

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

P. Flecknell, M. Macleod, B. McColl, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke

S. Allan, Catriona J Cunningham, E. Redondo‐Castro, 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A Multi-Model Pipeline for Translational Intracerebral Haemorrhage Research

A. Parry-Jones, S. Allan, P. Kasher, 2020, Translational Stroke Research.

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease

M. Z. Cader, Colin Smith, H. Markus, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Experimental Intracerebral Hemorrhage: Avoiding Pitfalls in Translational Research

A. Parry-Jones, S. Allan, M. Kirkman, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Therapeutic potential of extracellular vesicles in preclinical stroke models: a systematic review and meta-analysis

J. M. Thomas, S. Allan, C. Lawrence, 2020, BMJ Open Science.

Varied actions of proinflammatory cytokines on excitotoxic cell death in the rat central nervous system

S. Allan, 2002, Journal of neuroscience research.

Decreased haemodynamic response and decoupling of cortical gamma-band activity and tissue oxygen perfusion after striatal interleukin-1 injection

I. Schiessl, Myles Jones, J. Berwick, 2016, Journal of Neuroinflammation.

Systemic infection, inflammation and acute ischemic stroke

B. McColl, N. Rothwell, S. Allan, 2009, Neuroscience.

Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

N. Rothwell, D. Brough, S. Allan, 2012, Disease Models & Mechanisms.

Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat

N. Rothwell, S. Allan, R. Grundy, 1999, Brain Research.

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings

Gillian L. Currie, M. Good, P. Kehoe, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice

S. Allan, C. Lawrence, J. Konkel, 2019, International journal of stroke : official journal of the International Stroke Society.

Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

D. Brough, S. Allan, T. Tzeng, 2020, Immunology.

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Seth Love, Jason Berwick, Jozien Goense, 2016, Clinical science.

Microglial Priming as Trained Immunity in the Brain

D. Brough, S. Allan, J. Quintin, 2017, Neuroscience.

The Role of Pro‐ and Antiinflammatory Cytokines in Neurodegeneration

S. Allan, 2000, Annals of the New York Academy of Sciences.

Interleukin-1 and acute brain injury

A. Parry-Jones, S. Allan, Katie N. Murray, 2015, Front. Cell. Neurosci..

Revisiting promising preclinical intracerebral hemorrhage studies to highlight repurposable drugs for translation

A. Parry-Jones, S. Allan, P. Kasher, 2020, International journal of stroke : official journal of the International Stroke Society.

Interleukin‐1β and the interleukin‐1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat

N. Rothwell, S. Allan, C. Lawrence, 1998, The European journal of neuroscience.

Targeting neuronal homeostasis to prevent seizures

A. Trevelyan, S. Allan, R. Baines, 2022, bioRxiv.

Inflammation in central nervous system injury.

N. Rothwell, S. Allan, 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages

D. Brough, S. Allan, E. Lemarchand, 2022, Immunology.

Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer’s Disease

S. Allan, C. Lawrence, J. Rivers-Auty, 2016, Journal of Alzheimer's disease : JAD.

Maternal High-Fat Diet Worsens Memory Deficits in the Triple-Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease

S. Allan, C. Lawrence, Stuart M. Allan, 2014, PloS one.

S. Allan, C. Lawrence, T. Brown, 2012, Disease Models & Mechanisms.

S. Allan, C. Lawrence, T. Brown, 2012 .

The localization of Amyloid beta in mice brain

S. Allan, 2010 .

Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection

S. Allan, Ruth Forman, K. Else, 2017, Journal of Neuroinflammation.

Characterization of a mutant samhd1 zebrafish model implicates dysregulation of cholesterol biosynthesis in Aicardi-Goutières syndrome

S. Allan, G. Rice, T. Briggs, 2023, Frontiers in Immunology.

A dual role for interleukin-1 in LTP in mouse hippocampal slices

Fiona M. Ross, Nancy J. Rothwell, N. Rothwell, 2003, Journal of Neuroimmunology.

Translational models for vascular cognitive impairment: a review including larger species

M. Moss, R. Kalaria, A. Hainsworth, 2017, BMC Medicine.

Selective Liposomal Transport Through Blood Brain Barrier Disruption in Ischaemic Stroke Reveals Two Distinct Therapeutic Opportunities

I. Schiessl, S. Allan, Kostas Kostarelos, 2019, bioRxiv.

Neurodegenerative actions of interleukin‐1 in the rat brain are mediated through increases in seizure activity

N. Rothwell, S. Allan, L. Heenan, 2006, Journal of neuroscience research.

Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming.

N. Rothwell, D. Brough, S. Allan, 2018, ACS nano.

Preceding infection and risk of stroke: An old concept revived by the COVID-19 pandemic

B. McColl, S. Allan, Mitchell S. V. Elkind, 2020, International journal of stroke : official journal of the International Stroke Society.

Systemic inflammation affects reperfusion following transient cerebral ischaemia

I. Schiessl, S. Allan, C. Lawrence, 2016, Experimental Neurology.

Systemic immune activation shapes stroke outcome

S. Allan, Á. Dénes, Katie N. Murray, 2013, Molecular and Cellular Neuroscience.

Delayed reperfusion deficits after experimental stroke account for increased pathophysiology

Natasha Bray, Ingo Schiessl, I. Schiessl, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Does previous stroke modify the relationship between inflammatory biomarkers and clinical endpoints in CKD patients?

S. Allan, P. Kalra, A. Odudu, 2022, BMC Nephrology.

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice

S. Allan, C. Lawrence, M. Haley, 2019, Translational Stroke Research.

Cytokines in stroke.

S. Allan, C. Stock, 2004, Ernst Schering Research Foundation workshop.

Cardiovascular co-morbidities, inflammation and cerebral small vessel disease.

S. Allan, A. Greenstein, Craig J. Smith, 2021, Cardiovascular research.

Systemic conditioned medium treatment from interleukin-1 primed mesenchymal stem cells promotes recovery after stroke

S. Allan, E. Pinteaux, R. Wong, 2020, Stem Cell Research & Therapy.

Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast‐Enhanced MRI

G. Parker, D. Brough, R. Hinz, 2018, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

Anakinra in COVID-19: important considerations for clinical trials

D. Brough, H. Patel, S. Allan, 2020, The Lancet Rheumatology.

Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke

C. Garlanda, S. Allan, E. Pinteaux, 2018, Journal of Molecular Medicine.

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

Stephen H. Bell, M. Abramowicz, S. Allan, 2023, bioRxiv.

Zebrafish drug screening identifies candidate therapies for neuroprotection after spontaneous intracerebral haemorrhage

C. Anderson, A. Parry-Jones, S. Allan, 2022, Disease models & mechanisms.

Variations in inflammation-related genes may be associated with childhood febrile seizure susceptibility

J. Lamb, R. Appleton, S. Allan, 2014, Seizure.

Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming

S. Allan, E. Pinteaux, H. Brown, 2018, Stem Cell Research & Therapy.

Boron-Based Inhibitors of the NLRP 3 Inflammasome Graphical Abstract Highlights

N. Rothwell, D. Brough, S. Allan, 2022 .

Experimental Stroke-Induced Changes in the Bone Marrow Reveal Complex Regulation of Leukocyte Responses

B. McColl, N. Rothwell, S. Allan, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro

N. Rothwell, S. Allan, C. Kielty, 2017, Stem Cell Research & Therapy.

Neutrophil infiltration to the brain is platelet‐dependent, and is reversed by blockade of platelet GPIbα

B. McColl, B. Nieswandt, S. Allan, 2018, Immunology.

Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity

B. McColl, N. Rothwell, S. Allan, 2014, European journal of immunology.

Regulation of interleukin-1 in acute brain injury.

D. Brough, S. Allan, P. Tyrrell, 2011, Trends in pharmacological sciences.

Systemic Inflammation Impairs Tissue Reperfusion Through Endothelin-Dependent Mechanisms in Cerebral Ischemia

S. Williams, A. Parry-Jones, S. Allan, 2014, Stroke.

Itaconate and fumarate derivatives exert a dual inhibitory effect on canonical NLRP3 activation in macrophages and microglia

D. Brough, S. Allan, E. Lemarchand, 2021, bioRxiv.

A hyperacute immune map of ischaemic stroke patients reveals alterations to circulating innate and adaptive cells

S. Allan, J. Grainger, S. Hulme, 2020, Clinical and experimental immunology.

Long-term functional recovery and compensation after cerebral ischemia in rats

N. Rothwell, S. Allan, G. Metz, 2014, Behavioural Brain Research.

Development & automation of a novel [18F]F prosthetic group, 2-[18F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

D. Allsop, M. Taylor, S. Allan, 2016, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Assessing the contribution of inflammation in models of Alzheimer's disease.

S. Allan, H. Boutin, Stuart M Allan, 2011, Biochemical Society transactions.

AmpliTaq Gold DNA Polymerase The Most Referenced Brand of DNA Polymerase in the World Date : 2005-05

D. Harrison, S. Allan, 2005 .

SUBCUTANEOUS INTERLEUKIN-1 RECEPTOR ANTAGONIST IN ISCHEMIC STROKE (SCIL-STROKE): A RANDOMIZED CONTROLLED PHASE 2 TRIAL

N. Rothwell, A. Parry-Jones, S. Allan, 2018 .

Robust Thrombolytic and Anti-Inflammatory Action of a Constitutively Active ADAMTS13 Variant in Murine Stroke Models.

I. Schiessl, S. Allan, G. Coutts, 2021, Blood.

Glyceryl trinitrate for the treatment of ischaemic stroke: Determining efficacy in rodent and ovine species for enhanced clinical translation

I. Schiessl, S. Allan, P. Bath, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity

N. Rothwell, S. Allan, E. Pinteaux, 2008, Molecular and Cellular Neuroscience.

An Endovascular Perforation Model of Subarachnoid Haemorrhage in Rat Produces Heterogeneous Infarcts that Increase with Blood Load

N. Rothwell, S. Allan, A. Greenhalgh, 2012, Translational Stroke Research.

Site-specific actions of interleukin-1 on excitotoxic cell death in the rat striatum

N. Rothwell, S. Allan, R. Grundy, 2002, Brain Research.

State of Play Review on Haemorrhagic Stroke Basic science of intracerebral haemorrhage

S. Allan, 2014 .

Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming

S. Allan, E. Pinteaux, H. Brown, 2018, Stem Cell Research & Therapy.

Cortical Death Caused by Striatal Administration of AMPA and Interleukin-1 is Mediated by Activation of Cortical NMDA Receptors

N. Rothwell, S. Allan, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Use of interference reflection microscopy to monitor exocytosis and endocytosis in the presynaptic terminal of bipolar cells from the goldfish retina

N. Rothwell, S. Allan, A. Llobet, 2002 .

Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection

S. Allan, Ruth Forman, K. Else, 2017, Journal of Neuroinflammation.

Cytokines and acute neurodegeneration

N. Rothwell, S. Allan, N J Rothwell, 1997, Molecular Psychiatry.

Improved reperfusion following alternative surgical approach for experimental stroke in mice.

S. Allan, C. Gibson, Melissa Trotman-Lucas, 2020, F1000Research.

Pro-inflammatory cytokine interleukin-1β affects synaptic plasticity in mouse hippocampal slices

N. Rothwell, S. Allan, A. Verkhratsky, 2002 .

The Neurovascular Unit and the Key Role of Astrocytes in the Regulation of Cerebral Blood Flow

S. Allan, 2006, Cerebrovascular Diseases.

Preconditioning with interleukin-1 alpha is required for the neuroprotective properties of mesenchymal stem cells after ischaemic stroke in mice.

S. Allan, E. Pinteaux, Craig J. Smith, 2023, Journal of Cerebral Blood Flow and Metabolism.

Experimental Intracerebral Hemorrhage: Avoiding Pitfalls in Translational Research

A. Parry-Jones, S. Allan, M. Kirkman, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Inflammatory responses in the rat brain in response to different methods of intra-cerebral administration

S. Campbell, D. Anthony, S. Allan, 2008, Journal of Neuroimmunology.

Brain inflammation is induced by co-morbidities and risk factors for stroke

K. Herholz, B. McColl, N. Rothwell, 2011, Brain, Behavior, and Immunity.