Philip D. Compton

发表

Extensive Crosstalk Between O-GlcNAcylation and Phosphorylation Regulates Cytokinesis

J. Shabanowitz, D. Hunt, G. Hart, 2010, Science Signaling.

Mapping Intact Protein Isoforms in Discovery Mode Using Top Down Proteomics

Richard D. LeDuc, Bryan P. Early, N. Kelleher, 2011, Nature.

Spinning up mass spectrometry for whole protein complexes

N. Kelleher, Philip D. Compton, 2012, Nature Methods.

Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics*

N. Kelleher, Philip D. Compton, L. Fornelli, 2016, Molecular & Cellular Proteomics.

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts*

David Fenyö, Henry Rodriguez, Paul M Thomas, 2015, Molecular & Cellular Proteomics.

An informatic framework for decoding protein complexes by top-down mass spectrometry

Mikhail E. Belov, Neil L. Kelleher, Richard D. LeDuc, 2015, Nature Methods.

Multiplexed Mass Spectrometry of Individual Ions Improves Measurement of Proteoforms and Their Complexes

Danielle Tullman-Ercek, Neil L. Kelleher, Ryan T. Fellers, 2020, Nature Methods.

Spectrum of Apolipoprotein AI and Apolipoprotein AII Proteoforms and Their Associations With Indices of Cardiometabolic Health: The CARDIA Study

Richard D. LeDuc, N. Kelleher, D. Jacobs, 2021, Journal of the American Heart Association.

Optimizing capillary electrophoresis for top‐down proteomics of 30–80 kDa proteins

Neil L. Kelleher, N. Kelleher, Ioanna Ntai, 2014, Proteomics.

Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top Down Mass Spectrometry.

Neil L. Kelleher, Luis F. Schachner, M. Senko, 2020, Journal of proteome research.

Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions.

Neil L. Kelleher, Luis F. Schachner, N. Kelleher, 2020, Journal of the American Society for Mass Spectrometry.

On the scalability and requirements of whole protein mass spectrometry.

Leonid Zamdborg, Neil L. Kelleher, N. Kelleher, 2011, Analytical chemistry.

Autopilot: An Online Data Acquisition Control System for the Enhanced High-Throughput Characterization of Intact Proteins

Neil L. Kelleher, Ryan T. Fellers, N. Kelleher, 2014, Analytical chemistry.

STORI Plots Enable Accurate Tracking of Individual Ion Signals

Neil L. Kelleher, Bryan P. Early, Vlad Zabrouskov, 2019, Journal of The American Society for Mass Spectrometry.

Estimating the Distribution of Protein Post-Translational Modification States by Mass Spectrometry.

J. Gunawardena, N. Kelleher, Philip D. Compton, 2018, Journal of proteome research.

Standard Proteoforms and Their Complexes for Native Mass Spectrometry

Luis F. Schachner, N. Kelleher, Philip D. Compton, 2019, Journal of The American Society for Mass Spectrometry.

Optimization of electron transfer dissociation via informed selection of reagents and operating parameters.

J. Shabanowitz, D. Hunt, Philip D. Compton, 2012, Analytical chemistry.

A Novel Interface for High-Throughput Analysis of Biotherapeutics by Electrospray Mass Spectrometry.

G. A. Lazar, N. Kelleher, G. Lazar, 2019, Analytical chemistry.

Targeted detection and quantitation of histone modifications from 1,000 cells

Francine E. Garrett-Bakelman, N. Kelleher, A. Melnick, 2020, PloS one.

Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics*

Bryan P. Early, Joseph B. Greer, Chad R. Weisbrod, 2019, Molecular & Cellular Proteomics.

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques.

Ryan T. Fellers, N. Kelleher, R. Fellers, 2018, Analytical chemistry.

Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics

N. Kelleher, R. Mutharasan, P. Thomas, 2015, EuPA open proteomics.

The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics

Philip D. Compton, L. Fornelli, R. Julian, 2017, Journal of The American Society for Mass Spectrometry.

Voltage Rollercoaster Filtering of Low-Mass Contaminants During Native Protein Analysis.

M. Senko, N. Kelleher, G. McAlister, 2020, Journal of the American Society for Mass Spectrometry.

From protein complexes to subunit backbone fragments: a multi-stage approach to native mass spectrometry.

N. Kelleher, A. Makarov, E. Denisov, 2013, Analytical chemistry.

Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry

Richard D. LeDuc, Ryan T. Fellers, Bryan P. Early, 2017, Journal of The American Society for Mass Spectrometry.

Top-down characterization of endogenous protein complexes with native proteomics

Neil L Kelleher, Luca Fornelli, Luis F Schachner, 2017, Nature chemical biology.

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry.

Ryan T. Fellers, N. Kelleher, M. Abecassis, 2016, Journal of proteomics.

Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression

Ryan T. Fellers, M. Senko, N. Kelleher, 2015 .

Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.

Paul M Thomas, Neil L Kelleher, Bryan P. Early, 2012, Journal of proteome research.

Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin

N. Kelleher, R. V. Van Duyne, G. Schatz, 2017, Analytical chemistry.

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer.

Ryan T Fellers, Richard D LeDuc, Neil L Kelleher, 2017, Journal of proteome research.

Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression*

Ryan T. Fellers, M. Senko, N. Kelleher, 2015, Molecular & Cellular Proteomics.

Front-end electron transfer dissociation: a new ionization source.

J. Shabanowitz, D. Hunt, Philip D. Compton, 2013, Analytical chemistry.

Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry

Kristie L. Rose, J. Shabanowitz, D. Hunt, 2008, Nature Protocols.

Deep and quantitative top-down proteomics in clinical and translational research

Richard D. LeDuc, N. Kelleher, R. LeDuc, 2014, Expert review of proteomics.

Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry.

N. Kelleher, Philip D. Compton, L. Fornelli, 2015, International journal of mass spectrometry.

A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity.

Neil L Kelleher, Luca Fornelli, C Shad Thaxton, 2018, Journal of proteome research.

Measurement of Individual Ions Sharply Increases the Resolution of Orbitrap Mass Spectra of Proteins.

M. Senko, N. Kelleher, A. Makarov, 2019, Analytical chemistry.

Analysing protein post-translational modform regions by linear programming

Bryan P. Early, J. Gunawardena, N. Kelleher, 2018, bioRxiv.

Isotopic Resolution of Protein Complexes up to 466 kDa Using Individual Ion Mass Spectrometry.

M. Senko, N. Kelleher, Philip D. Compton, 2020, Analytical chemistry.

Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire

Richard D. LeDuc, Ryan T. Fellers, Bryan P. Early, 2021, Journal of proteome research.

Next-generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire

Bryan P. Early, N. Kelleher, R. LeDuc, 2021, medRxiv.

Fragmentation of Integral Membrane Proteins in the Gas Phase

Bryan P. Early, N. Kelleher, P. Thomas, 2014, Analytical chemistry.

Top down proteomics of human membrane proteins from enriched mitochondrial fractions.

Paul M Thomas, Neil L Kelleher, Bryan P. Early, 2013, Analytical chemistry.

A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies

Luis F. Schachner, N. Kelleher, W. Klein, 2019, Journal of neurochemistry.

Chromatographic efficiency and selectivity in top-down proteomics of histones.

N. Kelleher, Philip D. Compton, M. Wirth, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Multiplexed Mass Spectrometry of Individual Ions Improves Measurement of Proteoforms and Their Complexes

Ryan T. Fellers, Bryan P. Early, M. Senko, 2020, Nature Methods.

New Interface for Faster Proteoform Analysis: Immunoprecipitation Coupled with SampleStream-Mass Spectrometry.

N. Kelleher, J. Wilkins, Philip D. Compton, 2021, Journal of the American Society for Mass Spectrometry.

Online matrix removal platform for coupling gel-based separations to whole protein electrospray ionization mass spectrometry.

N. Kelleher, Philip D. Compton, J. C. Tran, 2015, Journal of proteome research.

Optimizing capillary electrophoresis for top‐down proteomics of 30–80 kDa proteins

N. Kelleher, Ioanna Ntai, Philip D. Compton, 2014, Proteomics.

Native GELFrEE: a new separation technique for biomolecular assemblies.

N. Kelleher, P. Havugimana, Philip D. Compton, 2015, Analytical chemistry.

Multiplexed Single Ion Mass Spectrometry Improves Measurement of Proteoforms and Their Complexes

Ryan T. Fellers, Bryan P. Early, M. Senko, 2019, bioRxiv.

High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry.

Philip D. Compton, A. M. Ovacik, Rachel Liuqing Shi, 2023, Analytical chemistry.

Deep and quantitative top-down proteomics in clinical and translational

P. Thomas, Ioanna Ntai, Philip D. Compton, 2014 .